Safety and Efficacy of Surgical Implantation of Intrathecal Drug Delivery Pumps in Patients With Cancer With Refractory Pain
CONCLUSION: Our study demonstrates that ITP implantation for the treatment of cancer-related pain is a safe and effective method of pain palliation with a low complication rate. Future prospective studies are required to determine the optimal timing of ITP implantation.PMID:38700319 | DOI:10.1227/neu.0000000000002978 (Source: Cancer Control)
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Graham M Winston Jeffrey H Zimering Christopher W Newman Anne S Reiner Noel Manalil Natasha Kharas Amitabh Gulati Neal Rakesh Ilya Laufer Mark H Bilsky Ori Barzilai Source Type: research
Distribution of Nerve Fibers in Abdominal Wall Endometriosis and Their Clinical Significance
CONCLUSION: This study demonstrated an increased immunoreactive nerve fiber density located in AWE lesions compared to normal abdominal wall scars. Further high-quality studies are needed to investigate the mechanisms responsible for pain in women with endometriosis.PMID:38699067 | PMC:PMC11063460 | DOI:10.2147/JPR.S453148 (Source: Cancer Control)
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Chenyu Zhang Yi Dai Junji Zhang Xiaoyan Li Shuangzheng Jia Jinghua Shi Jinhua Leng Source Type: research
Conversion ratios: Why is it so challenging to construct opioid conversion tables?
J Opioid Manag. 2024 Mar-Apr;20(2):169-179. doi: 10.5055/jom.0853.ABSTRACTStandardizing opioid management is challenging due to the absence of a ceiling dose, the unknown ideal therapeutic plasma level, and the lack of an clear relationship between dose and therapeutic response. Opioid rotation or conversion, which is switching from one opioid, route of administration, or both, to another, to improve therapeutic response and reduce toxicities, occurs in 20-40 percent of patients treated with opioids. Opioid conversion is often needed when there are adverse effects, toxicities, or inability to tolerate a certain opioid form...
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Mellar P Davis Mary Lynn McPherson Akhila Reddy Amy A Case Source Type: research
Claims data analysis of provider-to-provider tele-mentoring program impact on opioid prescribing in Missouri
CONCLUSIONS: Pain Management ECHO supports PCPs with needed education and skills to provide specialty care in the management of pain conditions and safe prescribing of opioid medications.PMID:38700394 | DOI:10.5055/jom.0825 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Olabode B Ogundele Xing Song Praveen Rao Tracy Greever-Rice Suzanne A Boren Karen Edison Douglas Burgess Mirna Becevic Source Type: research
Opioid use and disposal at 2 weeks post-surgery: Brief communication regarding excess opioids and disposal habits
CONCLUSION: Two-thirds of the patients reported having excess opioids, highlighting the issue of an overabundance of unused prescription opioids in America. Utilization of opioid-free pain management strategies and drug disposal kits should be explored to reduce the number of unused and improperly disposed opioids.PMID:38700391 | DOI:10.5055/jom.0854 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Henry Kuechly Sarah Kurkowski John Bonamer Brian Newyear Brian Johnson Brian Grawe Source Type: research
The Gluteus Deep Investing Fascia Compartment Block: A Novel Technique for Posterior Femoral Cutaneous Nerve Block
CONCLUSION: The GDIF block appears to be a promising technique for anesthetic management, alone or as part of the CLEFT block. Further research with a larger patient population is necessary to validate these findings.PMID:38699287 | PMC:PMC11064292 | DOI:10.2147/LRA.S455702 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - May 3, 2024 Category: Anesthesiology Authors: Majaliwa Shabani Seydina Alioune Beye Abdoulaye Traore Pablo Echave Xavier Raingeval Daouda Coulibaly Sophie Crespo Source Type: research
Enhanced Recovery After Surgery (ERAS) Spine Pathways and the Role of Perioperative Checklists
Adv Tech Stand Neurosurg. 2024;49:73-94. doi: 10.1007/978-3-031-42398-7_5.ABSTRACTEnhanced recovery after surgery (ERAS) proposes a multimodal, evidence-based approach to perioperative care. ERAS pathways have been shown to help reduce complications, hospital length of stay (LOS), 30-day readmission rates, pain scores, and ultimately surgical costs, while improving patient satisfaction scores and outcomes in multiple surgical subspecialties [1-6]. Numerous specialties have implemented ERAS programs across the globe, providing a foundation for spine surgeons to begin the process themselves. Over the last few years, a signif...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Scott C Robertson Source Type: research
Identification of Key Genes and Pathways in Oxaliplatin-Induced Neuropathic Pain Through Bioinformatic Analysis
(Source: Journal of Pain Research)
Source: Journal of Pain Research - May 3, 2024 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Randomised controlled trial of tourniquet associated pain generated in lower limb after exsanguination by Esmarch bandage versus limb elevation
This study was designed to compare what effect pre-tourniquet Esmarch bandage exsanguination has on pain... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - May 3, 2024 Category: Orthopaedics Authors: Alexander Mitrichev, John Maunder, Aiden Jabur, Prince Singh, Deborah Lees, Levi Morse and Benjamin Parkinson Tags: Research article Source Type: research
Effects of hand-press pellet on pain and daily life of elders with chronic lower back pain: randomized controlled trial
For elderly people with chronic lower back pain who need long-term management, there is a need for a nursing intervention study that is effective, is easy to perform, and applies complementary and alternative ... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - May 3, 2024 Category: Complementary Medicine Authors: Hyojung Park and Hyejin Lee Tags: Research Source Type: research
Modified botulinum toxin type A injections improve symptoms associated with interstitial cystitis/bladder pain syndrome in women: a retrospective cohort study
To investigate the efficacy and safety of modified botulinum toxin type A (BoNT-A) injections (with additional periurethral injection [PUI] of BoNT-A) for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). (Source: Urology)
Source: Urology - May 3, 2024 Category: Urology & Nephrology Authors: Yang Wang, Jianyi Zheng, Zeyu Li, Yuanhong Jiang, Jiazheng Yu, Shijie Li, Xiaonan Chen Source Type: research
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis
We previously reported that enhanced corticotropin-releasing factor (CRF) signaling in the bed nucleus of the stria terminalis (BNST) caused the aversive responses during acute pain and suppressed the brain re... (Source: Molecular Brain)
Source: Molecular Brain - May 3, 2024 Category: Neuroscience Authors: Ryoko Uchida, Yasutaka Mukai, Taiju Amano, Kenji Sakimura, Keiichi Itoi, Akihiro Yamanaka and Masabumi Minami Tags: Micro report Source Type: research
Decision Making of the In-season Athlete with Anterior Shoulder Instability
In-season management of anterior shoulder instability in athletes is a complex problem. Athletes often wish to play through their current season, though recurrent instability rates are high, particularly in contact sports. Athletes are generally considered safe to return to play when they are relatively pain-free, and their strength and range of motion match the uninjured extremity. If an athlete is unable to progress toward recovering strength and range of motion, surgical management is an option, though this is often a season-ending decision. (Source: Clinics in Sports Medicine)
Source: Clinics in Sports Medicine - May 3, 2024 Category: Sports Medicine Authors: Garrett V. Christensen, Olivia C. O ’Reilly, Brian R. Wolf Source Type: research
Complete Cam Resection Results in Best Outcomes After Hip Arthroscopy for Femoroacetabular Impingement
An aspherical hip can mechanically damage the joint and lead to chondrolabral injury, functional pain, and potentially arthritis. Hip arthroscopy to address femoroacetabular impingement (FAI) and make the hip spherical, with treatment of concomitant labral pathology, can result in excellent outcomes in patients with this pathology. The goal is complete cam resection. Cam pathology comes in many shapes, locations, and sizes — from smaller, anterolaterally located lesions to larger, pistol group lesions that extend more superiorly and lateral. (Source: Arthroscopy - Journal of Arthroscopic and Related Surgery)
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - May 3, 2024 Category: Surgery Authors: Stephen K. Aoki, Ameen Z. Khalil Tags: Editorial Commentary Source Type: research
Hip Arthroscopy in Patients with Spine Pain: Outcomes Vary Compared to Patients with Isolated Hip Pathology, but Many Hip-Spine Patients Do Just as Well
Low back pain present concurrently with hip impingement or labral pathology is frustrating for both patient and surgeon. It is difficult to distinguish true hip pathology from secondary low back symptoms, even with the use of diagnostic injections, cross-sectional imaging, electromyography, and/or nerve conduction studies. In addition, even properly indicated hip arthroscopy can exacerbate sciatic nerve dysfunction, a known complication from traction, and altered gait in the early postoperative period can aggravate sacroiliac and lumbar pathology. (Source: Arthroscopy - Journal of Arthroscopic and Related Surgery)
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - May 3, 2024 Category: Surgery Authors: Elizabeth J. Scott Tags: Editorial Commentary Source Type: research
