Management of Paget-Schroetter Syndrome: a Systematic Review and Meta-Analysis
CONCLUSION: Non-operative management of PSS with AC alone results in persistent symptoms in 46% of patients, while 96% of patients managed with CDT + FFR are symptom free at end of follow up. Superiority of CDT + FRR compared with AC, CDT + AC, and AC + FRR was confirmed by meta-analysis. The overall quality of included reports was moderate, and the level of certainty was "very low".PMID:37678659 | DOI:10.1016/j.ejvs.2023.08.065 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - September 7, 2023 Category: Surgery Authors: Frank Hoexum Max Hoebink Hans M E Coveliers Willem Wisselink Vincent Jongkind Kak Khee Yeung Source Type: research
Pulmonary Embolism following an undiagnosed Paget-Schroetter Syndrome: a case report and review of the literature
Phys Sportsmed. 2023 Sep 7. doi: 10.1080/00913847.2023.2256642. Online ahead of print.ABSTRACTPaget-Schroetter Syndrome (PSS) is a rare condition characterized as a spontaneous thrombosis of the axillary-subclavian vein that occurs predominantly in young athletes engaged with repetitive overhead upper extremity motion, for instance weightlifting, swimming, baseball, and tennis. PSS is usually a consequence of chronic repetitive microtrauma to the vein intima due to compression of the axillary-subclavian vein by the thoracic outlet structures. This chronic injury can then be acutely exacerbated by vigorous exercise done ove...
Source: The Physician and Sportsmedicine Online - September 7, 2023 Category: Sports Medicine Authors: Alexandre Negr ão Pantaleão Guillaume Goudot Luca Becari Vinicius Jeunon Guilherme Andrade Bello Alice Gallo Case Reportde Moraes Source Type: research
Management of Paget-Schroetter Syndrome: a Systematic Review and Meta-Analysis
CONCLUSION: Non-operative management of PSS with AC alone results in persistent symptoms in 46% of patients, while 96% of patients managed with CDT + FFR are symptom free at end of follow up. Superiority of CDT + FRR compared with AC, CDT + AC, and AC + FRR was confirmed by meta-analysis. The overall quality of included reports was moderate, and the level of certainty was "very low".PMID:37678659 | DOI:10.1016/j.ejvs.2023.08.065 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - September 7, 2023 Category: Surgery Authors: Frank Hoexum Max Hoebink Hans M E Coveliers Willem Wisselink Vincent Jongkind Kak Khee Yeung Source Type: research
Management of Paget-Schroetter Syndrome: a Systematic Review and Meta-Analysis
Currently, there is no consensus on the optimal management of Paget-Schroetter syndrome (PSS). Our objective was to summarise current evidence for management of PSS with explicit attention to the clinical outcomes of different management strategies. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - September 5, 2023 Category: Surgery Authors: Frank Hoexum, Max Hoebink, Hans M.E. Coveliers, Willem Wisselink, Vincent Jongkind, Kak Khee Yeung Tags: Systematic Review Source Type: research
Woven bone formation and mineralization by rat mesenchymal stromal cells imply increased expression of the intermediate filament desmin
ConclusionImmunocytochemical and morphometric studies coupled with proteomic and bioinformatic analysis support the concept that DES may act as an upstream signal for the skeletogenic commitment of rBMSCs. Thus, we suggest that altered metabolism of osteoblasts, woven bone, and mineralization by dysfunctional BMSCs might early be revealed by changes in DES expression//levels. Non-union fractures and endocrine – metabolic bone disorders like fibrous dysplasia and Paget disease of bone might take advantage of this molecular evidence for their early diagnosis and follow-up. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - September 4, 2023 Category: Endocrinology Source Type: research
Non-surgical treatment of Vulvar Paget disease
Asian J Surg. 2023 Aug 30:S1015-9584(23)01267-8. doi: 10.1016/j.asjsur.2023.08.113. Online ahead of print.NO ABSTRACTPMID:37657980 | DOI:10.1016/j.asjsur.2023.08.113 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - September 1, 2023 Category: Surgery Authors: Kai-Ge Pei Jia-Wen Zhang Source Type: research
Po118
We describe our clinical workflow, dosimetry and initial clinical outcome of treating extramammary Paget's disease (EMPD) using SMBT with 3D printed custom applicator. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2023 Category: Cancer & Oncology Authors: Moti Raj Paudel, Elizabeth A. Barnes, Mohammad Kazem, Amandeep S. Taggar Source Type: research
A clinicopathological and immunohistochemical profile of primary extra mammary paget & #39;s Disease in skin of colour: A case series
Subhra Dhar, Divya Gupta, Aditi Chakraborty, Rajib Malakar, Sandipan DharIndian Journal of Dermatology 2023 68(4):488-488
Extramammary Paget's disease is an intraepithelial neoplasm, usually found in areas rich in apocrine gland concentration. The clinical features, histopathology, immunohistochemistry and management details of five patients (F = 3, M = 2) have been described here. While a well-defined persistent plaque with crusting and erosion was the most common presentation, hyperpigmentation, hypopigmentation and depigmentation were also observed in two patients. Characteristic Paget&...
Source: Indian Journal of Dermatology - August 31, 2023 Category: Dermatology Authors: Subhra Dhar Divya Gupta Aditi Chakraborty Rajib Malakar Sandipan Dhar Source Type: research
Elevated Risk of Visceral Malignant Neoplasm in EMPD
This cross-sectional study evaluates the incidence and types of cancers that develop years after an extramammary Paget disease (EMPD) diagnosis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 30, 2023 Category: Dermatology Source Type: research
Role of androgen signaling in androgen receptor-positive extramammary Paget's disease: establishment of organoids and their biological analysis as a novel therapeutic target
Extramammary Paget ’s disease (EMPD) is a rare intraepithelial adenocarcinoma that mainly affects the anogenital and axillary regions. Although its etiology has not been fully elucidated, there is evidence that androgen receptors (AR) are expressed in most cases of EMPD. However, the role of androgen signaling in th e pathogenesis of EMPD remains unclear. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 29, 2023 Category: Dermatology Authors: Yoshio Nakamura, Hayase Mizukami, Keiji Tanese, Takayuki Fusumae, Ikuko Hirai, Masayuki Amagai, Reika Takamatsu, Kohei Nakamura, Hiroshi Nishihara, Tetsuya Takimoto, Masaru Ueno, Hideyuki Saya, Takeru Funakoshi Source Type: research
Maladie osseuse de Paget
CMAJ. 2023 Aug 28;195(33):E1138. doi: 10.1503/cmaj.230164-f.NO ABSTRACTPMID:37640400 | DOI:10.1503/cmaj.230164-f (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - August 28, 2023 Category: General Medicine Authors: Reza Pishdad Kendall F Moseley Source Type: research
Maladie osseuse de Paget
CMAJ. 2023 Aug 28;195(33):E1138. doi: 10.1503/cmaj.230164-f.NO ABSTRACTPMID:37640400 | DOI:10.1503/cmaj.230164-f (Source: cmaj)
Source: cmaj - August 28, 2023 Category: General Medicine Authors: Reza Pishdad Kendall F Moseley Source Type: research
Maladie osseuse de Paget
CMAJ. 2023 Aug 28;195(33):E1138. doi: 10.1503/cmaj.230164-f.NO ABSTRACTPMID:37640400 | PMC:PMC10462407 | DOI:10.1503/cmaj.230164-f (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - August 28, 2023 Category: General Medicine Authors: Reza Pishdad Kendall F Moseley Source Type: research
Maladie osseuse de Paget
CMAJ. 2023 Aug 28;195(33):E1138. doi: 10.1503/cmaj.230164-f.NO ABSTRACTPMID:37640400 | PMC:PMC10462407 | DOI:10.1503/cmaj.230164-f (Source: cmaj)
Source: cmaj - August 28, 2023 Category: General Medicine Authors: Reza Pishdad Kendall F Moseley Source Type: research
Maladie osseuse de Paget
CMAJ. 2023 Aug 28;195(33):E1138. doi: 10.1503/cmaj.230164-f.NO ABSTRACTPMID:37640400 | PMC:PMC10462407 | DOI:10.1503/cmaj.230164-f (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - August 28, 2023 Category: General Medicine Authors: Reza Pishdad Kendall F Moseley Source Type: research
