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Pregnant With a Rare Vasculitis: How to Treat Pregnant With a Rare Vasculitis: How to Treat
Dr Stephen Paget reviews the case of a 40-year-old woman with Takayasu arteritis being treated with prednisone.Hospital for Special Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2017 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

The psychiatric hospital discharge database (RIM-P): an essential tool for the surveillance of hospitalization after a suicide attempt - Chan Chee C, Paget LM.
BACKGROUND: Epidemiological surveillance of suicide attempts is essential for monitoring indicator trends in the evaluation of prevention actions. As part of this surveillance, analysis of data from hospitalization for suicide attempts is particularly usef... (Source: SafetyLit)
Source: SafetyLit - September 13, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Nurses hoping to encourage staff flu jabs with new game
Nurse innovators at James Paget Hospitals NHS Foundation Trust are hoping to create a “buzz” about flu vaccination this winter with a new online game featuring a flu-fighting bee. (Source: Nursing Times)
Source: Nursing Times - August 15, 2017 Category: Nursing Source Type: news

Under fire: the Falklands War and the revival of naval gunfire support - Paget S.
The provision of naval gunfire support was an important aspect of the Falklands War. By the end of the 1970s, naval gunfire support appeared to be doomed, but its vital role during the Falklands War led to a timely reappraisal. Indeed, the use of naval gun... (Source: SafetyLit)
Source: SafetyLit - August 15, 2017 Category: International Medicine & Public Health Tags: Commentary Source Type: news

Mylan Launches Generic Reclast(R) Injection
HERTFORDSHIRE, England and PITTSBURGH, June 2, 2017 -- (Healthcare Sales & Marketing Network) -- Mylan N.V. (NASDAQ, TASE: MYL) today announced the U.S. launch of Zoledronic Acid Injection, 5 mg/100 mL Single Dose Vial, a generic version of Novartis' Recl... Biopharmaceuticals, Generics, FDA, Product Launch Mylan, Zoledronic Acid, Reclast, Paget's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 2, 2017 Category: Pharmaceuticals Source Type: news

Handheld Microscopy May Help Detect Recurrent Extramammary Paget Disease Handheld Microscopy May Help Detect Recurrent Extramammary Paget Disease
Handheld reflectance confocal microscopy (HRCM) may help diagnose recurrent extramammary Paget disease (EMPD) and guide biopsy decision making, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - May 18, 2017 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Tingling, Pain, Rash, and Fatigue: Crack the Case Tingling, Pain, Rash, and Fatigue: Crack the Case
Rheumatologist Dr Stephen Paget presents a complicated case of a 35-year-old patient with an array of multisystem symptoms.Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 15, 2017 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Kissing Goodbye Sepsis at James Paget University Hospital
This article outlines a sepsis project at the James Paget University Hospital. The aim was to try to improve Sepsis outcomes at the Trust. They realised that that the key to succeed was to simplify and make it easy for frontline to identify Sepsis. They scrapped all paperwork and were left with just one simple tick box form that staff can complete in less than 30 seconds. They also empowered their specialist Nurses by launching a PGD for them to be able to administer first dose of antibiotics in special circumstances where the doctor is not available immediately. In 9 months the amount of patients given antibiotics inside ...
Source: Current Awareness Service for Health (CASH) - April 20, 2017 Category: Consumer Health News Source Type: news

Methods of data selection from the french medical information system program for trauma patient's analysis: burns and traumatic brain injuries - Paget LM, Dupont A, P édrono G, Lasbeur L, Thelot B.
BACKGROUND: Data from the French medical information system program in medicine, surgery, obstetrics and dentistry can be adapted in some cases and under certain conditions, to account for hospitalizations for injuries. Two areas have been explored: burn a... (Source: SafetyLit)
Source: SafetyLit - April 11, 2017 Category: Global & Universal Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Sodium citrate spray could temporarily restore sense of smell
(University of East Anglia) A substance commonly used to treat bladder issues could temporarily treat people who have lost their sense of smell, according to research published in the journal Clinical Otolaryngology.A study by the University of East Anglia (UEA) with the Smell& Taste clinic at the James Paget University Hospital showed sodium citrate nasal spray could offer temporary improvement in the ability to smell for patients suffering from anosmia or hyposmia- - the loss of smell -- in cases caused by a virus or other non-obstructive causes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2017 Category: Global & Universal Source Type: news

Researchers identify potential treatment for type of muscle and brain degenerative disease
In fruit flies modeled with IBMPFD disease, mitochondria (red circles) are severely disrupted. Treatment of VCP inhibitors in these diseased flies reversed  mitochondrial damage (green circles). FINDINGSUCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD. Using both genetically engineered fruit flies that have the fly equivalent of the disease gene as well as cells from people with IBMPFD, the researchers discovered how mutations carried by those with IBMPFD cau...
Source: UCLA Newsroom: Health Sciences - March 21, 2017 Category: Universities & Medical Training Source Type: news

Paget's Disease
Title: Paget's DiseaseCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/28/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 28, 2017 Category: Rheumatology Source Type: news

Intensive Bisphosphonate Therapy Questioned in Paget's Disease Intensive Bisphosphonate Therapy Questioned in Paget's Disease
The clinical benefit of long-term suppression of bone turnover with bisphosphonates in Paget's disease is questioned by extension findings from PRISM.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - February 14, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Insights on optimal treatment of Paget's disease of bone
In a study of patients with Paget's disease of bone -- a common skeletal disorder that can lead to bone deformity, fractures, osteoarthritis, and bone pain -- long-term intensive bisphosphonate therapy conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 8, 2017 Category: Science Source Type: news

Study provides insights on optimal treatment of Paget's disease of bone
(Wiley) In a study of patients with Paget's disease of bone--a common skeletal disorder that can lead to bone deformity, fractures, osteoarthritis, and bone pain -- long-term intensive bisphosphonate therapy conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 8, 2017 Category: Global & Universal Source Type: news

' Why I Went Into Rheumatology'' Why I Went Into Rheumatology '
The practice of rheumatology demands extraordinary clinical and investigative skills, but if you are up to this challenge, you will never regret it, says Dr Stephen Paget.Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 7, 2017 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Portuguese man says staff forced him to stay in hospital
Adriano Guedes was admitted to the James Paget Hospital in Norfolk following a stroke in August 2014. But he was removed after the hospital obtained a court order on January 10 this year. (Source: the Mail online | Health)
Source: the Mail online | Health - January 24, 2017 Category: Consumer Health News Source Type: news

'I was forced to stay': Man hits back after eviction
Adriano Guedes was admitted to the James Paget Hospital in Norfolk following a stroke in August 2014. But he was removed after the hospital obtained a court order on January 10 this year. (Source: the Mail online | Health)
Source: the Mail online | Health - January 24, 2017 Category: Consumer Health News Source Type: news

James Paget Hospital patient evicted after two years
A hospital patient who occupied a bed for more than years was evicted after a hospital applied for a court order. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 20, 2017 Category: Consumer Health News Source Type: news

Hospital takes legal action to evict bed blocker
The patient arrived at the James Paget University Hospital in Norfolk in August 2014 and remained there until this year. But he was deemed 'fit for discharge', according to the BBC. (Source: the Mail online | Health)
Source: the Mail online | Health - January 20, 2017 Category: Consumer Health News Source Type: news

Norfolk hospital trust appoints director of nursing
Julia Hunt has been appointed as the new director of nursing at James Paget University Hospitals NHS Foundation Trust in Norfolk. (Source: Nursing Times)
Source: Nursing Times - January 5, 2017 Category: Nursing Source Type: news

Severe Testicular Pain: Crack the Case Severe Testicular Pain: Crack the Case
Dr Stephen Paget reviews the case of a 32-year-old man with severe testicular pain for 2 years.Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 3, 2017 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

A Painful, Red Wrist: Crack the Case A Painful, Red Wrist: Crack the Case
Infection? Pseudogout? Both? Dr Paget discusses the interesting case of a 76-year-old man with pain and swelling in his wrist.Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 23, 2016 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Choosing a Management Strategy in RA Choosing a Management Strategy in RA
Drs Paget and Bykerk discuss the current data on treatment timing, disease modification, and comorbidities in rheumatoid arthritis.Hospital for Special Surgery eAcademy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 30, 2016 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Comorbidities in Inflammatory Joint Disease Comorbidities in Inflammatory Joint Disease
Drs Paget and Schwartzman discuss both rare and common comorbidities, and the latest strategies to prevent their damaging effects.Hospital for Special Surgery eAcademy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 30, 2016 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Bristol runner who blamed sports bra for rash is devastated to be told she has breast cancer
Sarah Lang, 32, from Bristol, was diagnosed with news she had Paget's disease of the nipple, a rare type of cancer. She has now undergone a full mastectomy and will start chemotherapy shortly. (Source: the Mail online | Health)
Source: the Mail online | Health - August 17, 2016 Category: Consumer Health News Source Type: news

A Tricky Case of Arm Pain and a Swollen Ear A Tricky Case of Arm Pain and a Swollen Ear
A 52-year-old woman's symptoms initially suggest polychondritis, but a viral infection could be to blame. Dr Stephen Paget shares the case details. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 27, 2016 Category: Consumer Health News Tags: Rheumatology Clinical Case Source Type: news

Another Vacation, Another Bout of Back Pain: A Case Another Vacation, Another Bout of Back Pain: A Case
Dr Stephen Paget shares the details of a patient who, for the second time in as many years, was rendered almost incapacitated during international travel. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 20, 2016 Category: Consumer Health News Tags: Rheumatology Clinical Case Source Type: news

Factors associated with suicide attempts by sexual minorities: Results from the 2011 Gay and Lesbian Survey - Paget LM, Chan Chee C, Sauvage C, Saboni L, Beltzer N, Velter A.
BACKGROUND: Since the 1990s, several studies have found higher rates of suicide attempts in homosexuals and bisexuals than in heterosexuals. The current challenge is to identify risk factors for targeting prevention. The aim of this paper was to determine,... (Source: SafetyLit)
Source: SafetyLit - May 28, 2016 Category: Global & Universal Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

Mohs with CK-7 staining: 98% 5-year cure rate for extramammary Paget disease
ORLANDO – Mohs surgery with cytokeratin-7 immunohistochemistry staining effected complete removal of extramammary Paget disease and resulted in a 5-year, 95% recurrence-free cure rate. The results are significantly better than the often-cited 77% cure rate seen with Mohs surgery alone, Dr. Ali... (Source: Skin and Allergy News)
Source: Skin and Allergy News - April 28, 2016 Category: Dermatology Source Type: news

Your NEJM Group Today: Paget Disease of Bone, Acute Liver Failure Outcomes, Montana Internist Opportunity (FREE)
By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today: NEJM Clinical Practice Center: Image in Clinical … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 4, 2016 Category: Primary Care Source Type: news

'This is not what I signed up for'
  Anger, betrayal, and a drain of talent overseas — that’s what an imposed contract would mean for the junior doctors taking a third period of industrial action. Doctors in Southampton said they were strongly committed to the NHS and its values, but those values were being put under severe threat by the Government’s plans. Portsmouth specialty trainee 1 in radiology Mohamed Ismail said he chose to train in the NHS because he loves its ethos. As an Irish national, who studied medicine in Sudan (where his family is from), he applied to England to get training that he believed would be excellent, in a ...
Source: BMA News - March 9, 2016 Category: UK Health Source Type: news

Scans reveal cyst on woman's ovary after doctors blamed pain on being obese
Doctors at James Paget Hospital in Norfolk discovered that a 'morbidly obese' 22-year-old woman had a huge cyst on her ovaries filled with six liters of blood-like fluid - that her GP thought was just fat. (Source: the Mail online | Health)
Source: the Mail online | Health - February 12, 2016 Category: Consumer Health News Source Type: news

Bowel and Brain Symptoms: What's the Connection? Bowel and Brain Symptoms: What's the Connection?
Dr Stephen Paget shares a case in which a patient with inflammatory bowel disease begins manifesting neurologic symptoms, challenging initial assumptions regarding her diagnosis. Medscape Rheumatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 26, 2016 Category: Gastroenterology Tags: Rheumatology Clinical Case Source Type: news

Improving the quality of initial management of self harm and suicide patients in A+E at the James Paget Hospital - Cracknell B.
Our objective was to improve the initial management and documentation of suicide risk assessment in the notes of patients attending A+E with a suicide attempt or self harm. An initial audit was carried out in 2012 looking at the notes of 50 patients who at... (Source: SafetyLit)
Source: SafetyLit - January 18, 2016 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

When Is 'Sarcoidosis' Not Sarcoidosis?When Is 'Sarcoidosis' Not Sarcoidosis?
Dr Stephen Paget discusses a case that illustrates the importance of a thorough differential diagnosis when assessing for sarcoidosis. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 13, 2016 Category: Consumer Health News Tags: Rheumatology Clinical Case Source Type: news

Which children and young people are excluded from school? Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) - Paget A, Parker C, Henley W, Heron J, Ford T, Emond A.
BACKGROUND: School exclusion is a disciplinary method used to remove a child from the school environment. It is known to affect certain groups disproportionately, including boys, some ethnic minorities, children in care, children in poverty, and children w... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 11, 2015 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Rock climbing-related subclavian vein thrombosis - Lutter C, Monasterio E, Schöffl V.
Paget-Schroetter syndrome, also known as upper extremity deep venous thrombosis (UEDVT), is a rare condition, characterised by a (sub-) total occlusion of the axillary-subclavian venous system due to thrombosis. UEDVT is the most common vascular condition ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 11, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Low Back Pain and GI Symptoms on the Swiss AlpsLow Back Pain and GI Symptoms on the Swiss Alps
Dr Paget discusses a recent patient of his who presented with a 5-year history of recurrent severe low back pain and gastrointestinal symptoms. Medscape Rheumatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 26, 2015 Category: Gastroenterology Tags: Rheumatology Commentary Source Type: news

Pain, Papular Lesions, a Trip to Pakistan: Crack the CasePain, Papular Lesions, a Trip to Pakistan: Crack the Case
Dr Paget discusses one of his recent patients who returned from a trip to Pakistan 5 years ago and since then has never been the same. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 19, 2015 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

Joint Pain, Inflammation, and a Caribbean Vacation: A CaseJoint Pain, Inflammation, and a Caribbean Vacation: A Case
Dr Paget discusses a recent patient of his who returned from a cruise in the Caribbean with severe joint pain and inflammation. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - August 15, 2015 Category: Rheumatology Tags: Rheumatology Commentary Source Type: news

Biosimilars: Unanswered QuestionsBiosimilars: Unanswered Questions
Dr Paget discusses the potential impact of biosimilars in rheumatology and some of the unanswered questions about their use. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - August 7, 2015 Category: Rheumatology Tags: Rheumatology Commentary Source Type: news

Using Lab Tests to Guide Anti-TNF Treatment in RAUsing Lab Tests to Guide Anti-TNF Treatment in RA
Dr Paget discusses some of the challenges of anti-TNF therapy in RA therapy as well as the utility of measuring serum drug levels and testing for neutralizing antibodies. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 4, 2015 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

James Paget University Hospitals Foundation Trust
Best Places to Work 2015 - Acute Trusts (Source: HSJ)
Source: HSJ - July 9, 2015 Category: UK Health Source Type: news

James May 'perished because on-call doctors failed to answer calls'
James May, 76, from Great Yarmouth died at the James Paget Hospital when 'chaos' descended on A&E and the on-call consultants refused to come into the hospital to help when called, an inquest has heard. (Source: the Mail online | Health)
Source: the Mail online | Health - May 20, 2015 Category: Consumer Health News Source Type: news

'Study medical notes carefully', urge family of man given do not resuscitate notice without consent
Grandfather Michael Richardson was so ill that existence of do not resuscitate order approved without family consultation did not cause his death, coroner concludes (Source: Telegraph Health)
Source: Telegraph Health - March 18, 2015 Category: Consumer Health News Tags: Michael Richardson DNR Norfolk Great Yarmouth James Paget University Do not rescucitate Source Type: news

Norfolk hospital staff 'played God' with DNR notice
Widow claims NHS staff put unrequested do not resuscitate notice on Michael Richardson before he died at James Paget University Hospital in Gorleston (Source: Telegraph Health)
Source: Telegraph Health - March 16, 2015 Category: Consumer Health News Tags: Michael Richardson DNR Norfolk Great Yarmouth James Paget University Do not rescucitate Source Type: news

A Puzzling Case of Painful Sclerotic Pelvic LesionsA Puzzling Case of Painful Sclerotic Pelvic Lesions
A woman is diagnosed with probable cancer, but all biopsies are negative. Dr Paget explains how he arrived at the correct diagnosis. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2015 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

6 Penis Problems That Happen With Age
SPECIAL FROM Grandparents.com You’d like to think that at least some areas of our bodies will be spared the indignities of aging, but one day you realize: Mr. Happy gets older, too. “You don’t wake up one morning and realize it is different. It’s a gradual process, but starting around age 40, the changes become more noticeable,” says Madeleine Castellanos, M.D., author of "Penis Problems: A Man's Guide." So what does it mean when a penis looks and acts different? Color Atherosclerosis, a common problem of aging, restricts blood flow, affecting heart, brain, and penis. With less blo...
Source: Healthy Living - The Huffington Post - January 15, 2015 Category: Consumer Health News Source Type: news