Three-dimensional gingival morphology in the aesthetic zone of maxillary anterior teeth: a cone-beam CT analysis
CONCLUSIONS: There were significant differences in the measuring results of GT, KGW, and SGT in the maxillary anterior region under different gingival biotypes, and individualized treatment strategies can be formulated based on gingival biotypes.PMID:37154000 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - May 8, 2023 Category: Dentistry Authors: Wen-Li Wang Ya-Ting Fu Hua Liu Xiao Ma Source Type: research
Mechanistic studies on the effect of easy degradable carbon on pharmaceuticals removal in intermittently fed Moving Bed Biofilm Reactors
This study was conducted to provide for the first time systematic data on how intermittent feeding with carbon (ethanol) affects the kinetics of pharmaceuticals degradation in a moving bed biofilm reactor (MBBR). The relationship between the degradation rate constants (K) of 36 pharmaceuticals and the length of famine was tested with 12 different feast-famine ratios: For 17 pharmaceuticals, intermittent feeding increased K with a factor of 3-17, while for six other pharmaceuticals, it decreased K. Concerning intermittent loading, three dependencies were detected: 1) for some compounds (e.g., valsartan, ibuprofen, iohexol),...
Source: Bioresource Technology - April 26, 2023 Category: Biotechnology Authors: Sif Svendsen Lucas Rebien J ørgensen Chuanzhou Liang Pedro N Carvalho Sille Bendix Larsen Kai Bester Source Type: research
Mechanistic studies on the effect of easy degradable carbon on pharmaceuticals removal in intermittently fed Moving Bed Biofilm Reactors
This study was conducted to provide for the first time systematic data on how intermittent feeding with carbon (ethanol) affects the kinetics of pharmaceuticals degradation in a moving bed biofilm reactor (MBBR). The relationship between the degradation rate constants (K) of 36 pharmaceuticals and the length of famine was tested with 12 different feast-famine ratios: For 17 pharmaceuticals, intermittent feeding increased K with a factor of 3-17, while for six other pharmaceuticals, it decreased K. Concerning intermittent loading, three dependencies were detected: 1) for some compounds (e.g., valsartan, ibuprofen, iohexol),...
Source: Bioresource Technology - April 26, 2023 Category: Biotechnology Authors: Sif Svendsen Lucas Rebien J ørgensen Chuanzhou Liang Pedro N Carvalho Sille Bendix Larsen Kai Bester Source Type: research
Nitric Oxide Precursors and Dimethylarginines as Risk Markers for Accelerated Measured GFR Decline in the General Population
CONCLUSIONS: Associations between NO precursors and the outcomes suggest that NO metabolism plays a significant role in the pathogenesis of age-related GFR decline and the development of CKD in middle-aged people.PMID:37069987 | PMC:PMC10105054 | DOI:10.1016/j.ekir.2023.01.015 (Source: Atherosclerosis)
Source: Atherosclerosis - April 18, 2023 Category: Cardiology Authors: Nikoline B Rinde Inger Therese Enoksen Toralf Melsom Ole Martin Fuskev åg Bj ørn Odvar Eriksen Jon Viljar Norvik Source Type: research
Halved contrast medium dose in lower limb dual-energy computed tomography angiography —a randomized controlled trial
ConclusionsHalf iodine-load SDCT lower limb CTA at 40 keV achieved higher VA than the control. CNR, SNR, noise, and SEQ were higher at 40 keV, while 50 keV showed lower noise.Clinical relevance statementSpectral detector CT with low-energy virtual monoenergetic imaging performed halved iodine contrast medium (CM) lower limb CT-angiography with sustained objective and subjective quality. This facilitates CM reduction, improvement of low CM-dosage examinations, and examination of patients with more severe kidney impairment.Trial registrationRetrospectively registered 5 August 2022 at clinicaltrials.gov NCT05488899.Key Po...
Source: European Radiology - April 18, 2023 Category: Radiology Source Type: research
Novel metabolites to improve glomerular filtration rate estimation
Conclusion: We screened out the metabolites that increased or decreased with mGFR decline in CKD patients from the Chinese population, and 10 of them were highly correlated. They are potential novel metabolites to improve GFR estimation. (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 10, 2023 Category: Urology & Nephrology Source Type: research
A comparison of the use of contrast media with different iodine concentrations for enhanced computed tomography
Conclusion: When a similar IDR and the same iodine load are used, CT images with different concentrations of contrast media have the same subjective and objective quality, and can meet the diagnostic needs. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 30, 2023 Category: Physiology Source Type: research
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis
ConclusionThe immune system and inflammation are key factors in DI-AKI. We discovered the immunological and inflammatory-related genes TLR4, AOC3, IRF4, and TNFAIP6, which may be promising specific biomarkers and essential hub genes for the prevention and identification of DI-AKI. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 29, 2023 Category: Allergy & Immunology Source Type: research
A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction
ConclusionThe hybrid model proposed significantly improved isavuconazole AUC estimation over MAP-BE based on the sole C24h and may improve dose adjustment.Graphical Abstract (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - March 29, 2023 Category: Drugs & Pharmacology Source Type: research
Gastroparesis after video-assisted thoracic surgery: A case report
CONCLUSION: Although gastroparesis is a rare perioperative complication following VATS, clinicians should be on the alert when patients complain about gastrointestinal discomfort. When surgeons resect paraesophageal lymph nodes with electrocautery, excessive ambient heat and compression of paraesophageal hematoma might induce vagal nerve dysfunction.PMID:36969994 | PMC:PMC10037284 | DOI:10.12998/wjcc.v11.i8.1862 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 27, 2023 Category: Cancer & Oncology Authors: Hang An Yu-Cun Liu Source Type: research
Gastroparesis after video-assisted thoracic surgery: A case report
CONCLUSION: Although gastroparesis is a rare perioperative complication following VATS, clinicians should be on the alert when patients complain about gastrointestinal discomfort. When surgeons resect paraesophageal lymph nodes with electrocautery, excessive ambient heat and compression of paraesophageal hematoma might induce vagal nerve dysfunction.PMID:36969994 | PMC:PMC10037284 | DOI:10.12998/wjcc.v11.i8.1862 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 27, 2023 Category: Cancer & Oncology Authors: Hang An Yu-Cun Liu Source Type: research
GSE227970 Identification and Validation of Hub Genes in Drug Induced Acute Kidney Injury Basing on Integrated Transcriptomic Analysis
In this study, RNA-seq was used to detect mRNA changes in DI-AKI cell models induced by three drugs (Iohexol, cisplatin and vancomycin), and was analyzed and validated to screen key hub genes and specific biomarkers for DI-AKI. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 27, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Gold cluster encapsulated liposomes: theranostic agent with stimulus triggered release capability
AbstractCancer is a major cause of death worldwide. Cancer-resistant to chemo or radiotherapy treatment is a challenge that could be overcome by a nanotechnology approach. Providing a theranostic nano-platform for different cancer treatment strategies could be revolutionary. Here we introduce a multifunctional theranostic nanostructure which has the capacity for improving cancer diagnosis and treatment through better chemo and radiotherapy and current x-ray imaging systems through co-encapsulation of a small gold cluster and anticancer drug doxorubicin. 2 nm gold clusters represent good heating under radio frequency elec...
Source: Medical Oncology - March 24, 2023 Category: Cancer & Oncology Source Type: research
Best Practice Recommendations for Stroke Vascular Imaging During Iodinated Contrast Shortage
GE Healthcare© announced on April 19, 2022, that their main factory and distributor of iodinated contrast had experienced a temporary shutdown because of COVID-19 outbreak in Shanghai, China. This, along with other supply chain issues, led to a worldwide shortage of iodinated contrast agents, Omnipaque and Visipaque. Our Comprehensive Stroke Center was confronted with the cascading effect of this iodinated contrast material shortage. We took immediate steps to revise our protocols and processes to continue to provide high-quality care to our stroke patients. A multidisciplinary working group comprised of representativ...
Source: Neurology Clinical Practice - March 3, 2023 Category: Neurology Authors: Bhole, R., Solenski, N. J., Donahue, J. H., Kellogg, R. T., Roach, N. N., Chapman, S. N., Worrall, B. B., Evans, A. J., Patel, S. H., Mukherjee, S., Park, M. S., Southerland, A. M. Tags: Decision analysis, Medical care, All Cerebrovascular disease/Stroke, All Practice Management Commentary Source Type: research
