Relationship of Serum Soluble Klotho Levels and Echocardiographic Parameters in Patients on Maintenance Hemodialysis
Conclusions: The present study showed that patients with lower circulating s-Klotho levels were more often associated with larger IVST and greater ratios of IVST and PWT. There was an independent association between s-Klotho and IVST, and lower s-Klotho levels seem to be a potential risk factor of uremic cardiomyopathy in MHD patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

Intensive versus Usual Control of Hypertension in the Prevention of Cardiovascular and Renal Outcomes: A Cumulative Meta-Analysis of Randomized Controlled Trials
Conclusion: The findings of this study suggest that IBP control plays a beneficial role in the prevention of some major cardiovascular events, including myocardial infarction, stroke, and albuminuria.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

5-Hydroxyhexanoic Acid Predicts Early Renal Functional Decline in Type 2 Diabetes Patients with Microalbuminuria
Conclusion: We have identified urine metabolites and shown that 5-hydroxyhexanoic acid can be used as a predictor of progression of ERFD in T2D patients with MA. This finding provides the new perspective that 5-hydroxyhexanoic acid may be useful to identify T2D patients with MA who are at risk of ERFD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

Genetic Variations rs859, rs4646, and rs372883 in the 3 ′-Untranslated Regions of Genes Are Associated with a Risk of IgA Nephropathy
Conclusion: Our results suggested that theIL-16 rs859,CYP19A1 rs4646, andBACH1 rs372883 polymorphisms have potential roles in the genetic susceptibility to IgAN in Chinese Han population.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

Oral Sodium Bicarbonate Supplementation Does Not Affect Serum Calcification Propensity in Patients with Chronic Kidney Disease and Chronic Metabolic Acidosis
Conclusion: Oral sodium bicarbonate supplementation showed no effect on T50-time in acidotic CKD patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

WNT4 Expression in Primary and Secondary Kidney Diseases: Dependence on Staging
Conclusions: Our results suggest that alteredWNT4 gene expression in patients with different types of glomerular diseases and patients at different stages of CKD may play a role in kidney tissue disorganization as well as disease development and progression.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

Conservative Care, Dialysis Withdrawal, and Palliative Care: Results from a Survey of a Non-Profit Dialysis Provider in Germany
Conclusion: Compared to international numbers, in Germany, proportion of CRC and DW reported by non-profit renal centers is in the lower range. Center practice of palliative care management varies and is driven by availability of local palliative care resources and presumably by attitudes of the renal teams. Quality of palliative care and the decision-making process need further evaluation.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 5, 2019 Category: Urology & Nephrology Source Type: research

Relationships of Chronic Kidney Disease and Thyroid Dysfunction in Non-Dialysis Patients: A Pilot Study
Conclusion: CKD patients have a high morbidity of ESS, mainly low T3 syndrome. Anemia, inflammation, and malnutrition may contribute to ESS in CKD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 25, 2019 Category: Urology & Nephrology Source Type: research

Comparison of Solute Clearance, Hospitalization Rate, and Aortic Arch Calcification between Online Hemodiafiltration and High-Flux Hemodialysis: A 6-Year Observational Study
Conclusion: Hospitalization rates and AAC were observed to be equal for HDF and HFHD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 16, 2019 Category: Urology & Nephrology Source Type: research

N-Acetylcysteine and Sulodexide Reduce the Prothrombotic Effect of Uremic Serum on the Venous Endothelial Cells
Conclusions: Uremic serum induces prothrombotic changes in VEC, which may cause a predisposition to thrombotic disorders in patients with renal failure. NAC and SUL reduce the effects of the uremic serum in VEC, which suggests their potential therapeutic application in uremic patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 16, 2019 Category: Urology & Nephrology Source Type: research

The SGLT2 Inhibitor Empagliflozin Might Be a New Approach for the Prevention of Acute Kidney Injury
Three randomized control trials (Canagliflozin Cardiovascular Assessment Study, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients [EMPA-REG OUTCOME], and Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 58 [DECLARE-TIMI 58]) showed that the sodium-glucose co-transporter 2 (SGLT2) inhibitors, originally developed as glucose-lowering drugs, are associated with a lower rate of adverse renal outcomes, such as need for renal replacement therapy, doubling of serum creatinine, and loss of glomerular filtration rate (GFR) compared to those in placebo groups. Be...
Source: Kidney and Blood Pressure Research - April 3, 2019 Category: Urology & Nephrology Source Type: research

Involvement of STAT3 Signaling in High Glucose-Induced Epithelial Mesenchymal Transition in Human Peritoneal Mesothelial Cell Line HMrSV5
Conclusion: Our results revealed a critical role for STAT3 signaling in high glucose-induced EMT in HMrSV5 cells, and suggested that inhibition of STAT3 might be a treatment for high glucose-induced fibrogenesis in PF.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 3, 2019 Category: Urology & Nephrology Source Type: research

Baseline Serum Magnesium Level and Its Variability in Maintenance Hemodialysis Patients: Associations with Mortality
Conclusions: The lower baseline serum magnesium level was associated with all-cause and cardiovascular mortality in MHD patients. However, the variability of magnesium level was not independently associated with the risk of death and further studies need to be conducted.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 31, 2019 Category: Urology & Nephrology Source Type: research

Association of Intraoperative Hypotension with Acute Kidney Injury after Noncardiac Surgery in Patients Younger than 60 Years Old
Conclusion: There was a considerably increased risk of postoperative AKI when intraoperative MAP was less than 55 mm Hg for more than 10 min. Strict blood pressure management is recommended even for patients younger than 60 years old.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 31, 2019 Category: Urology & Nephrology Source Type: research

Association of Lean Body Mass Index and Peritoneal Protein Clearance in Peritoneal Dialysis Patients
Conclusion: Higher LBMI was independently associated with higher , indicating that better nutritional status dominates peritoneal protein metabolism in PD patients.Kidney Blood Press Res 2019;44:94 –102 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 15, 2019 Category: Urology & Nephrology Source Type: research

Effects of Vitamin D Supplementation on Renal Function, Inflammation and Glycemic Control in Patients with Diabetic Nephropathy: a Systematic Review and Meta-Analysis
Conclusion: In patients with DN, VD supplementation provides beneficial effects on 24-hour urine protein and inflammation indexes, but not on SCr, eGFR or glycemic control indexes. More RCTs that comprehensively evaluate the impact of VD supplementation on indexes of renal function, inflammation and glycemic control in DN atients are required in order to reach conclusive results.Kidney Blood Press Res 2019;44:72 –87 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells
Conclusion: Interestingly, cytosolic sensors of viral RNA were found to be involved in IL-6 production via TLR3 signaling in GECs. Regional activation of TLR3/IFN- β/ MDA5/RIG-I/IL-6 axis due to viral and “pseudoviral” infections is involved in innate immunity and inflammatory reactions in GECs. We believe this signaling pathway also plays a pivotal role in the development of some forms of GN.Kidney Blood Press Res 2019;44:62 –71 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Association Between the Lipid Profile and Renal Dysfunction in the Heart Failure Patients
Conclusion: Among the lipid profile of TC, triglyceride, LDL-C, HDL-C, apo A1 and apo B, the HDL-C is the only lipid factor significantly associated with renal dysfunction in hospitalized heart failure patients.Kidney Blood Press Res 2019;44:52 –61 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Hemodialysis Experience of a Large Group of Syrian Refugees in Turkey: All Patients Deserve Effective Treatment
Conclusion: This study with the largest number of Syrian refugees undergoing maintenance hemodialysis showed good dialysis practices, acceptable values for dialysis adequacy and biochemical parameters along with lower mortality compared to native HD population of Turkey. Longer follow up will enrich the knowledge related to care of refugee population in all over the world.Kidney Blood Press Res 2019;44:43 –51 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Clinical Significance of Crescent Formation in IgA Nephropathy – a Multicenter Validation Study
Conclusion: The C score in the Oxford classification is a valid predictive parameter for IgAN prognosis. Additional clinical attention is necessary for IgAN patients with identified cellular or fibrocellular crescents.Kidney Blood Press Res 2019;44:22 –32 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

A Fast Decline of Residual Renal Function in the First Year is a Predictor for Early Withdrawal from Peritoneal Dialysis in Non-Diabetic Patients
Conclusion: A faster RRF decline in the first year was a predictor for all-cause mortality and conversion to HD in non-diabetic PD patients, mainly in the first three year. For patients with faster RRF decline, increasing PD dose was effective to improve survival.Kidney Blood Press Res 2019;44:12 –21 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Paternal Programming of Liver Function and Lipid Profile Induced by a Paternal Pre-Conceptional Unhealthy Diet: Potential Association with Altered Gut Microbiome Composition
Conclusion: Taken together, our findings suggested that a paternal pre-conceptional unhealthy diet predisposes the offspring to mild liver function alterations and alterations of gut microbiota in later life. Effects on lipids were sex-specific and only seen in male offspring.Kidney Blood Press Res 2019;44:133 –148 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser < sup > 40 < /sup > : An Alternative Route for Dopamine Synthesis and Modulation of Na < sup > + < /sup > /K < sup > + < /sup > -ATPase in Kidney Cells
Conclusion: The results indicate that DA formed mainly from luminal L-tyr or L-dopa uptake by LAT2, can inhibit the Na+/K+-ATPase. In addition, our results showed for the very first time that TH activity is also significantly increased when the cells were exposed to L-tyr.Kidney Blood Press Res 2019;44:1 –11 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Increased Microalbuminuria Risk in Male Cigarette Smokers: Results from the “Olivetti Heart Study” after 8 Years Follow-Up
Conclusion: In a selected male adult population sample, cigarette smoke was independently associated with the development of higher levels of albuminuria over time.Kidney Blood Press Res 2019;44:33 –42 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Influence of Hemofiltration on Intradialytic Plasma Volume Decrease
Conclusion: Online mode hemofiltration, in either pre-dilution mode or post-dilution mode, performed in combination with hemodialysis has no preventive effect on IPVD.Kidney Blood Press Res 2019;44:88 –93 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

The Association of Echocardiographic Peak Systolic Strain Rate with Cardiovascular Outcomes in Haemodialysis Patients
Conclusion: SR demonstrates association with outcome in this population and highlights the consideration that such sub-clinical cardiac changes should be routinely sought when referring haemodialysis patients for cardiac assessments.Kidney Blood Press Res 2018;43:1935 –1942 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Association of Geriatric Nutritional Risk Index with Mortality in Hemodialysis Patients: A Meta-Analysis of Cohort Studies
Conclusion: Our findings supported the hypothesis that the low GNRI is associated with an increased risk of all-cause and cardiovascular mortality in chronic hemodialysis patients. Based on our literature review, GNRI has been found to be an effective tool for identifying patients with nutrition-related risk of all-cause and cardiovascular disease.Kidney Blood Press Res 2018;43:1878 –1889 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Efficacy and Safety of Agents in IgA Nephropathy: An Update Network Meta-Analysis
Conclusion: RASi combined with steroid demonstrated the most effective therapeutic approach for IgA nephropathy patients in terms of reducing proteinuria and stabilizing renal function.Kidney Blood Press Res 2018;43:1890 –1897 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Bioinformatic Analyses of Renal Ischaemia-Reperfusion Injury Models: Identification of Key Genes Involved in the Development of Kidney Disease
Conclusion:Timp1,Spp1,Dmgdh, miR-142-5p and miR-181a may be potential targets or biomarkers for the development of renal IRI.Kidney Blood Press Res 2018;43:1898 –1907 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Impact of Self-Report and eGFR-Based Chronic Kidney Disease on the Risk of Chronic Kidney Disease-Related Complications and Geriatric Syndromes in Community-Dwelling Older Adults
Conclusion: Among older adults, self-reported CKD may not be a surrogate for laboratory-diagnosed CKD and has an independent effect on CKD-related complications.Kidney Blood Press Res 2018;43:1908 –1918 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Immediate and Late Effects of Stress on Kidneys of Prepubertal and Adult Rats
Conclusion: Chronic stress induced before and after puberty led to irreversible glomerular loss, however, renal impairment was interrupted by removal of the stress stimuli.Kidney Blood Press Res 2018;43:1919 –1926 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Overproduction of Mitochondrial Fission Proteins in Membranous Nephropathy in Children
Conclusion: Glomerular overproduction of Drp1, phospho-Drp1 (Ser 616) and Fis1 occurred mainly in children with membranous nephropathy. The pathological significance deserves further investigation.Kidney Blood Press Res 2018;43:1927 –1934 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Erratum
Kidney Blood Press Res 2018;43:1878 –1878 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 14, 2018 Category: Urology & Nephrology Source Type: research

Erratum
Kidney Blood Press Res 2018;43:1879 –1879 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 14, 2018 Category: Urology & Nephrology Source Type: research

Alterations of Renal Epithelial Glucose and Uric Acid Transporters in Fructose Induced Metabolic Syndrome
Conclusion: Long term high fructose diet induced metabolic syndrome with increased blood pressure and proteinuria in rats. Metabolic syndrome was associated with dual increase in renal glucose and uric acid transporters, including SGLT1, SGLT2, GLUT2, GLUT9 and UAT.Kidney Blood Press Res 2018;43:1822 –1831 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 7, 2018 Category: Urology & Nephrology Source Type: research

Nomogram Model to Predict Cardiorenal Syndrome Type 1 in Patients with Acute Heart Failure
Conclusion: The proposed nomogram could predict the individualized risk of CRS1 with good accuracy, high discrimination, and potential clinical applicability in patients with AHF.Kidney Blood Press Res 2018;43:1832 –1841 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 7, 2018 Category: Urology & Nephrology Source Type: research

Proteinuria, Estimated Glomerular Filtration Rate and Urinary Retinol-Binding Protein as Clinical Predictors of Long-Term Allograft Outcomes in Transplant Glomerulopathy
Conclusion: Five clinical features —impaired renal function, higher proteinuria, higher urRBP level, male sex and HCV infection—are independent predictors of an unfavorable renal allograft outcome. urRBP is a simple and useful parameter that can add invaluable information for the clinical follow-up of patients with TG.Kidney Blood Press Res 2018;43:1842 –1851 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 7, 2018 Category: Urology & Nephrology Source Type: research

Prediction of ESRD in IgA Nephropathy Patients from an Asian Cohort: A Random Forest Model
Conclusion: In addition to the predictors in the CDSS, Oxford-MEST scores, C3 staining and eGFR conveyed additional information for ESRD prediction in Chinese IgAN patients using a RF model.Kidney Blood Press Res 2018;43:1852 –1864 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 7, 2018 Category: Urology & Nephrology Source Type: research

Renal Functions and Prognosis Stratification in Chronic Heart Failure Patients and the Importance of Neutrophil Gelatinase-Associated Lipocalin
Conclusion: The findings of the study showed that NGAL associated with NT-proBNP was a stronger predictor of the primary endpoint than NGAL or NT-proBNP alone. The level of NGAL was rising in hypertension, ischemia, anemia, hypoalbuminemia, diabetes or arrhythmias.Kidney Blood Press Res 2018;43:1865 –1877 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 7, 2018 Category: Urology & Nephrology Source Type: research

Phosphate Homeostasis, Inflammation and the Regulation of FGF-23
Fibroblast growth factor 23 (FGF23) is released primarily from osteoblasts/osteocytes in bone. In cooperation with the transmembrane protein Klotho, FGF23 is a powerful inhibitor of 1 α 25OH Vitamin D Hydroxylase (Cyp27b1) and thus of the formation of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). As 1,25(OH)2D3 up-regulates intestinal calcium and phosphate absorption, the downregulation of 1,25(OH)2D3 synthesis counteracts phosphate excess and tissue calcification. FGF23 also directly inhibits renal phosphate reabsorption. Other actions of FGF23 include triggering of cardiac hypertrophy. FGF23 formation and/or release are ...
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Probability of At Least One High Arterial Blood Pressure Measurement in Elderly Patients with Healthy Vascular Aging in Two Years of Follow-Up
Conclusion: Vascular health in elderly individuals seems to protect against occasional elevations in systemic arterial pressure.Kidney Blood Press Res 2018;43:1765 –1771 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

The Kidney Specific Protein < b > < i > myo < /i > < /b > -Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy
Conclusion: These data indicate that increased MIOX expression in the kidney contributes to tubular damage in DN. The concentration of MIOX in the serum and urine may serve as a new biomarker for the early diagnosis of DN.Kidney Blood Press Res 2018;43:1772 –1785 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Potential Blood Pressure Goals in IgA Nephropathy: Prevalence, Awareness, and Treatment Rates in Chronic Kidney Disease Among Patients with Hypertension in China (PATRIOTIC) Study
Conclusion: Hypertension was common in IgA nephropathy and hypertensive control was suboptimal. Our result supports a benefit of intensive control of BP #x3c; 130/80 mmHg for patients with proteinuria ≥1 g/d. However, in patients with proteinuria #x3c; 1 g/d, a renoprotective effect of this BP goal was not identified.Kidney Blood Press Res 2018;43:1786 –1795 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Patients with Atrial Fibrillation and Chronic Kidney Disease More Often Undergo Angioplasty of Left Main Coronary Artery – a 867 Patient Study
Conclusion: Patients with CKD had more often permanent type of AF. Percutaneous interventions of the left main coronary artery, the only elective procedures influencing patients ’ prognosis, were done more frequently in CKD patients with AF. In-hospital mortality was significantly higher in patients with severe renal impairment. Despite the higher risk of ischaemic stroke in CKD group the use of oral anticoagulation therapy was significantly less frequent and the patients were deprived of the confirmed benefits of such treatment.Kidney Blood Press Res 2018;43:1796 –1805 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Clinical Manifestation, Management and Prognosis of Acute Myocardial Infarction in Autosomal Dominant Polycystic Kidney Disease
Conclusion: ADPKD patients with AMI suffer from more severe conditions and difficult therapies, resulting in a poorer prognosis.Kidney Blood Press Res 2018;43:1806 –1812 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Hemodialysis or Peritoneal Dialysis, Which Is Better for Patients with Delayed Graft Function?
Conclusion: In renal transplant recipients with DGF, post-transplant PD led to increased treatment failure. PD did not result in rapid recovery of transplanted renal function, and had a high probability of peritonitis.Kidney Blood Press Res 2018;43:1813 –1821 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Early Start Peritoneal Dialysis: Technique Survival in Long-Term Follow-Up
Conclusion: Despite the adverse scenario for initiating dialysis, early start PD had similar outcomes in comparison to planned-start PD in long-term follow-up.Kidney Blood Press Res 2018;43:1699 –1705 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 23, 2018 Category: Urology & Nephrology Source Type: research

Patients with Hypertensive Nephropathy and Chronic Kidney Disease Might Not Benefit from Strict Blood Pressure Control
Conclusion: In patients with CKD and HN+ maintenance of BP targets recommended by current guidelines is less reno-protective than it is in HN-.Kidney Blood Press Res 2018;43:1706 –1715 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 23, 2018 Category: Urology & Nephrology Source Type: research

Urinary Level of Liver-Type Fatty Acid Binding Protein Reflects the Degree of Tubulointerstitial Damage in Polycystic Kidney Disease
Conclusion: Urinary L-FABP reflects the progression of tubulointerstitial damage, and therefore, may be a useful marker for monitoring the progression of PKD.Kidney Blood Press Res 2018;43:1716 –1729 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 23, 2018 Category: Urology & Nephrology Source Type: research

The Role of Renal Vascular Reactivity in the Development of Renal Dysfunction in Compensated and Decompensated Congestive Heart Failure
Conclusion: Greater renal vasoconstrictor responsiveness to ANG II or reduced renal vasodilatation in response to Ach do not play a decisive role in the development of renal dysfunction in ACF rats with compensated and decompensated CHF. On the other hand, exaggerated renal vascular responsiveness to NE may be here a contributing causative factor, active in either CHF phase.Kidney Blood Press Res 2018;43:1730 –1741 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - November 23, 2018 Category: Urology & Nephrology Source Type: research