Erratum
Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - July 5, 2019 Category: Urology & Nephrology Source Type: research

Hypercalcemia Is a Risk Factor for the Progression of Aortic Calcification in Kidney Transplant Recipients
Conclusion: The present study revealed that hypercalcemia is a risk factor for the development of infrarenal abdominal AoC in KTRs. Furthermore, the effect of hypercalcemia was greater in patients with more severe vascular calcification.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - July 2, 2019 Category: Urology & Nephrology Source Type: research

Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Containing Pyrin Domain 3 Inflammasome Activation
Elevated homocysteine (Hcy) levels have been shown to activate nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome leading to podocyte dysfunction and glomerular injury. However, it remains unclear how this inflammasome activation in podocytes is a therapeutic target for reversal of glomerular injury and ultimate sclerosis. The present study tested whether inhibition of Rac1 GTPase activity suppresses NLRP3 inflammation activation and thereby blocks podocyte injury induced by elevated Hcy. In cultured podocytes, we found that L-Hcy (the active Hcy form) stimulated the NLRP...
Source: Kidney and Blood Pressure Research - July 2, 2019 Category: Urology & Nephrology Source Type: research

Blood Oxygen Level-Dependent Imaging and Intravoxel Incoherent Motion MRI of Early Contrast-Induced Acute Kidney Injury in a Rabbit Model
Conclusion: BOLD combined with IVIM is effective to monitor renal pathophysiology associated with CIAKI.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 28, 2019 Category: Urology & Nephrology Source Type: research

Revised Equations to Estimate Glomerular Filtration Rate from Serum Creatinine and Cystatin C in China
Conclusion: C-CKD-EPIcys was the most accurate with the highest P30 value, relative lowest IQR, and RMSE among 6 equations. C-CKD-EPIscr and C-CKD-EPIscr-cys equations were improved in bias, precision, and accuracy. Other external validation of these equations is needed.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 28, 2019 Category: Urology & Nephrology Source Type: research

Evaluation of Electrocardiographic Parameters Predicting Cardiovascular Events in Patients with End-Stage Renal Disease before and after Transplantation
Conclusions: Taken together, we found an increased T:R ratio in ESRD patients to be a predictive marker for CV events.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 26, 2019 Category: Urology & Nephrology Source Type: research

Phospholipase A2 Receptor Antibody IgG4 Subclass Improves Sensitivity and Specificity in the Diagnosis of Idiopathic Membranous Nephropathy
Conclusion: The serum anti-phospholipase A2 receptor IgG4 detected with the method developed in this study has higher sensitivity and higher specificity than total IgG in the diagnosis of IMN.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 26, 2019 Category: Urology & Nephrology Source Type: research

Urotensin II Induces Mice Skeletal Muscle Atrophy Associated with Enhanced Autophagy and Inhibited Irisin Precursor (Fibronectin Type III Domain Containing 5) Expression in Chronic Renal Failure
Conclusion: We are the first to verify UII induces mice skeletal muscle atrophy associated with enhanced skeletal muscle autophagy and inhibited FNDC5 expression in chronic renal failure.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 25, 2019 Category: Urology & Nephrology Source Type: research

Association between Body Weight Gain from 20 Years of Age and Diabetic Nephropathy in Japanese Patients with Type 2 Diabetes
Conclusions: BW gain from the age of 20 years is correlated with diabetic nephropathy in Japanese patients with type 2 diabetes.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 25, 2019 Category: Urology & Nephrology Source Type: research

Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury
Conclusions: Caspase-11-induced pyroptosis of RTECs is a key event during septic AKI, and targeting of caspase-11 in RTECs may serve as a novel therapeutic target in septic AKI.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 21, 2019 Category: Urology & Nephrology Source Type: research

A Body Mass Index-Based Cross-Classification Approach for the Assessment of Prognostic Factors in Chronic Kidney Disease Progression
Conclusion: A BMI-based cross-classification approach, which provides more comprehensive findings than that in previous approaches, is expected to be an effective method for evaluating renal prognostic factors in patients with CKD who are affected by multiple risk factors.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 14, 2019 Category: Urology & Nephrology Source Type: research

Free 25-Vitamin D Is Correlated with Cardiovascular Events in Prevalent Hemodialysis Patients but Not with Markers of Renal Mineral Bone Disease
In conclusion, our study shows that free vitamin D serum concentrations are independently associated with major cardiovascular events in chronic kidney disease patients on dialysis.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 14, 2019 Category: Urology & Nephrology Source Type: research

High-Mobility Group Nucleosome-Binding Protein 1 Mediates Renal Fibrosis Correlating with Macrophages Accumulation and Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy Mice Model
Conclusion: HMGN1 may promote macrophages accumulation and EMT, suggesting a potential therapeutic target for preventing renal fibrosis development in DN.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 14, 2019 Category: Urology & Nephrology Source Type: research

Use of Both Serum Cystatin C and Creatinine as Diagnostic Criteria for Cardiac Surgery-Associated Acute Kidney Injury and Its Correlation with Long-Term Major Adverse Events
Conclusion: Combining sCyC and sCr to diagnose CSA-AKI would be beneficial for risk stratification and prognosis in patients after cardiac surgery.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 12, 2019 Category: Urology & Nephrology Source Type: research

Association between Serum Magnesium and Erythropoietin Responsiveness in Hemodialysis Patients: A Cross-Sectional Study
Conclusion: Serum magnesium levels were higher than normal levels in MHD patients. A high serum magnesium level was correlated with good EPO responsiveness and was therefore suggested to be a protective factor for EPO hyporesponsiveness.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 12, 2019 Category: Urology & Nephrology Source Type: research

Matrix Metalloproteinases in Renal Diseases: A Critical Appraisal
Matrix metalloproteinases (MMPs) are endopeptidases within the metzincin protein family that not only cleave extracellular matrix (ECM) components, but also process the non-ECM molecules, including various growth factors and their binding proteins. MMPs participate in cell to ECM interactions, and MMPs are known to be involved in cell proliferation mechanisms and most probably apoptosis. These proteinases are grouped into six classes: collagenases, gelatinases, stromelysins, matrilysins, membrane type MMPs, and other MMPs. Various mechanisms regulate the activity of MMPs, inhibition by tissue inhibitors of metalloproteinas...
Source: Kidney and Blood Pressure Research - June 11, 2019 Category: Urology & Nephrology Source Type: research

MicroRNA-26a: An Emerging Regulator of Renal Biology and Disease
MicroRNAs (miRNAs) are short, single-stranded, noncoding RNAs that modulate many key biological processes by simultaneously suppressing multiple target genes. Among them, miR-26a, a conserved miRNA among vertebrates, is highly expressed in various tissues. Accumulating evidence demonstrates that miR-26a plays pivotal roles in cellular differentiation, cell growth, apoptosis, and metastasis, thereby participating in the initiation and development of various human diseases, such as metabolic disease and cancer. More recently, miR-26a was found as a versatile regulator of renal biology and disease. miR-26a is intensively invo...
Source: Kidney and Blood Pressure Research - June 4, 2019 Category: Urology & Nephrology Source Type: research

Association between Plasma Levels of Growth Differentiation Factor-15 and Renal Function in the Elderly: Korean Frailty and Aging Cohort Study
Conclusion: Plasma GDF-15 levels were negatively associated with eGFR and were significantly increased in the elderly with CKD. Our results suggested that plasma GDF-15 might be a useful marker for discriminating renal impairment in the elderly. Further large and prospective outcome studies of extended duration are needed.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - June 4, 2019 Category: Urology & Nephrology Source Type: research

Arterial Stiffness as a Risk Factor for Subclinical Coronary Artery Calcification in Predialysis Chronic Kidney Disease: From the KNOW-CKD Study
Conclusion: Increased arterial stiffness measured by high baPWV was associated with CAC in a predialysis CKD cohort. Longitudinal studies are needed to determine the effect of arterial stiffness on the development or progression of CAC in CKD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 27, 2019 Category: Urology & Nephrology Source Type: research

Relationship of Serum Soluble Klotho Levels and Echocardiographic Parameters in Patients on Maintenance Hemodialysis
Conclusions: The present study showed that patients with lower circulating s-Klotho levels were more often associated with larger IVST and greater ratios of IVST and PWT. There was an independent association between s-Klotho and IVST, and lower s-Klotho levels seem to be a potential risk factor of uremic cardiomyopathy in MHD patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

Intensive versus Usual Control of Hypertension in the Prevention of Cardiovascular and Renal Outcomes: A Cumulative Meta-Analysis of Randomized Controlled Trials
Conclusion: The findings of this study suggest that IBP control plays a beneficial role in the prevention of some major cardiovascular events, including myocardial infarction, stroke, and albuminuria.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

5-Hydroxyhexanoic Acid Predicts Early Renal Functional Decline in Type 2 Diabetes Patients with Microalbuminuria
Conclusion: We have identified urine metabolites and shown that 5-hydroxyhexanoic acid can be used as a predictor of progression of ERFD in T2D patients with MA. This finding provides the new perspective that 5-hydroxyhexanoic acid may be useful to identify T2D patients with MA who are at risk of ERFD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 10, 2019 Category: Urology & Nephrology Source Type: research

Genetic Variations rs859, rs4646, and rs372883 in the 3 ′-Untranslated Regions of Genes Are Associated with a Risk of IgA Nephropathy
Conclusion: Our results suggested that theIL-16 rs859,CYP19A1 rs4646, andBACH1 rs372883 polymorphisms have potential roles in the genetic susceptibility to IgAN in Chinese Han population.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

Oral Sodium Bicarbonate Supplementation Does Not Affect Serum Calcification Propensity in Patients with Chronic Kidney Disease and Chronic Metabolic Acidosis
Conclusion: Oral sodium bicarbonate supplementation showed no effect on T50-time in acidotic CKD patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

WNT4 Expression in Primary and Secondary Kidney Diseases: Dependence on Staging
Conclusions: Our results suggest that alteredWNT4 gene expression in patients with different types of glomerular diseases and patients at different stages of CKD may play a role in kidney tissue disorganization as well as disease development and progression.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 8, 2019 Category: Urology & Nephrology Source Type: research

Conservative Care, Dialysis Withdrawal, and Palliative Care: Results from a Survey of a Non-Profit Dialysis Provider in Germany
Conclusion: Compared to international numbers, in Germany, proportion of CRC and DW reported by non-profit renal centers is in the lower range. Center practice of palliative care management varies and is driven by availability of local palliative care resources and presumably by attitudes of the renal teams. Quality of palliative care and the decision-making process need further evaluation.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - May 5, 2019 Category: Urology & Nephrology Source Type: research

Relationships of Chronic Kidney Disease and Thyroid Dysfunction in Non-Dialysis Patients: A Pilot Study
Conclusion: CKD patients have a high morbidity of ESS, mainly low T3 syndrome. Anemia, inflammation, and malnutrition may contribute to ESS in CKD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 25, 2019 Category: Urology & Nephrology Source Type: research

Comparison of Solute Clearance, Hospitalization Rate, and Aortic Arch Calcification between Online Hemodiafiltration and High-Flux Hemodialysis: A 6-Year Observational Study
Conclusion: Hospitalization rates and AAC were observed to be equal for HDF and HFHD.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 16, 2019 Category: Urology & Nephrology Source Type: research

N-Acetylcysteine and Sulodexide Reduce the Prothrombotic Effect of Uremic Serum on the Venous Endothelial Cells
Conclusions: Uremic serum induces prothrombotic changes in VEC, which may cause a predisposition to thrombotic disorders in patients with renal failure. NAC and SUL reduce the effects of the uremic serum in VEC, which suggests their potential therapeutic application in uremic patients.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 16, 2019 Category: Urology & Nephrology Source Type: research

The SGLT2 Inhibitor Empagliflozin Might Be a New Approach for the Prevention of Acute Kidney Injury
Three randomized control trials (Canagliflozin Cardiovascular Assessment Study, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients [EMPA-REG OUTCOME], and Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 58 [DECLARE-TIMI 58]) showed that the sodium-glucose co-transporter 2 (SGLT2) inhibitors, originally developed as glucose-lowering drugs, are associated with a lower rate of adverse renal outcomes, such as need for renal replacement therapy, doubling of serum creatinine, and loss of glomerular filtration rate (GFR) compared to those in placebo groups. Be...
Source: Kidney and Blood Pressure Research - April 3, 2019 Category: Urology & Nephrology Source Type: research

Involvement of STAT3 Signaling in High Glucose-Induced Epithelial Mesenchymal Transition in Human Peritoneal Mesothelial Cell Line HMrSV5
Conclusion: Our results revealed a critical role for STAT3 signaling in high glucose-induced EMT in HMrSV5 cells, and suggested that inhibition of STAT3 might be a treatment for high glucose-induced fibrogenesis in PF.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - April 3, 2019 Category: Urology & Nephrology Source Type: research

Baseline Serum Magnesium Level and Its Variability in Maintenance Hemodialysis Patients: Associations with Mortality
Conclusions: The lower baseline serum magnesium level was associated with all-cause and cardiovascular mortality in MHD patients. However, the variability of magnesium level was not independently associated with the risk of death and further studies need to be conducted.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 31, 2019 Category: Urology & Nephrology Source Type: research

Association of Intraoperative Hypotension with Acute Kidney Injury after Noncardiac Surgery in Patients Younger than 60 Years Old
Conclusion: There was a considerably increased risk of postoperative AKI when intraoperative MAP was less than 55 mm Hg for more than 10 min. Strict blood pressure management is recommended even for patients younger than 60 years old.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 31, 2019 Category: Urology & Nephrology Source Type: research

Association of Lean Body Mass Index and Peritoneal Protein Clearance in Peritoneal Dialysis Patients
Conclusion: Higher LBMI was independently associated with higher , indicating that better nutritional status dominates peritoneal protein metabolism in PD patients.Kidney Blood Press Res 2019;44:94 –102 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - March 15, 2019 Category: Urology & Nephrology Source Type: research

Effects of Vitamin D Supplementation on Renal Function, Inflammation and Glycemic Control in Patients with Diabetic Nephropathy: a Systematic Review and Meta-Analysis
Conclusion: In patients with DN, VD supplementation provides beneficial effects on 24-hour urine protein and inflammation indexes, but not on SCr, eGFR or glycemic control indexes. More RCTs that comprehensively evaluate the impact of VD supplementation on indexes of renal function, inflammation and glycemic control in DN atients are required in order to reach conclusive results.Kidney Blood Press Res 2019;44:72 –87 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells
Conclusion: Interestingly, cytosolic sensors of viral RNA were found to be involved in IL-6 production via TLR3 signaling in GECs. Regional activation of TLR3/IFN- β/ MDA5/RIG-I/IL-6 axis due to viral and “pseudoviral” infections is involved in innate immunity and inflammatory reactions in GECs. We believe this signaling pathway also plays a pivotal role in the development of some forms of GN.Kidney Blood Press Res 2019;44:62 –71 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Association Between the Lipid Profile and Renal Dysfunction in the Heart Failure Patients
Conclusion: Among the lipid profile of TC, triglyceride, LDL-C, HDL-C, apo A1 and apo B, the HDL-C is the only lipid factor significantly associated with renal dysfunction in hospitalized heart failure patients.Kidney Blood Press Res 2019;44:52 –61 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Hemodialysis Experience of a Large Group of Syrian Refugees in Turkey: All Patients Deserve Effective Treatment
Conclusion: This study with the largest number of Syrian refugees undergoing maintenance hemodialysis showed good dialysis practices, acceptable values for dialysis adequacy and biochemical parameters along with lower mortality compared to native HD population of Turkey. Longer follow up will enrich the knowledge related to care of refugee population in all over the world.Kidney Blood Press Res 2019;44:43 –51 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Clinical Significance of Crescent Formation in IgA Nephropathy – a Multicenter Validation Study
Conclusion: The C score in the Oxford classification is a valid predictive parameter for IgAN prognosis. Additional clinical attention is necessary for IgAN patients with identified cellular or fibrocellular crescents.Kidney Blood Press Res 2019;44:22 –32 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

A Fast Decline of Residual Renal Function in the First Year is a Predictor for Early Withdrawal from Peritoneal Dialysis in Non-Diabetic Patients
Conclusion: A faster RRF decline in the first year was a predictor for all-cause mortality and conversion to HD in non-diabetic PD patients, mainly in the first three year. For patients with faster RRF decline, increasing PD dose was effective to improve survival.Kidney Blood Press Res 2019;44:12 –21 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Paternal Programming of Liver Function and Lipid Profile Induced by a Paternal Pre-Conceptional Unhealthy Diet: Potential Association with Altered Gut Microbiome Composition
Conclusion: Taken together, our findings suggested that a paternal pre-conceptional unhealthy diet predisposes the offspring to mild liver function alterations and alterations of gut microbiota in later life. Effects on lipids were sex-specific and only seen in male offspring.Kidney Blood Press Res 2019;44:133 –148 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser < sup > 40 < /sup > : An Alternative Route for Dopamine Synthesis and Modulation of Na < sup > + < /sup > /K < sup > + < /sup > -ATPase in Kidney Cells
Conclusion: The results indicate that DA formed mainly from luminal L-tyr or L-dopa uptake by LAT2, can inhibit the Na+/K+-ATPase. In addition, our results showed for the very first time that TH activity is also significantly increased when the cells were exposed to L-tyr.Kidney Blood Press Res 2019;44:1 –11 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Increased Microalbuminuria Risk in Male Cigarette Smokers: Results from the “Olivetti Heart Study” after 8 Years Follow-Up
Conclusion: In a selected male adult population sample, cigarette smoke was independently associated with the development of higher levels of albuminuria over time.Kidney Blood Press Res 2019;44:33 –42 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

Influence of Hemofiltration on Intradialytic Plasma Volume Decrease
Conclusion: Online mode hemofiltration, in either pre-dilution mode or post-dilution mode, performed in combination with hemodialysis has no preventive effect on IPVD.Kidney Blood Press Res 2019;44:88 –93 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - February 25, 2019 Category: Urology & Nephrology Source Type: research

The Association of Echocardiographic Peak Systolic Strain Rate with Cardiovascular Outcomes in Haemodialysis Patients
Conclusion: SR demonstrates association with outcome in this population and highlights the consideration that such sub-clinical cardiac changes should be routinely sought when referring haemodialysis patients for cardiac assessments.Kidney Blood Press Res 2018;43:1935 –1942 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Association of Geriatric Nutritional Risk Index with Mortality in Hemodialysis Patients: A Meta-Analysis of Cohort Studies
Conclusion: Our findings supported the hypothesis that the low GNRI is associated with an increased risk of all-cause and cardiovascular mortality in chronic hemodialysis patients. Based on our literature review, GNRI has been found to be an effective tool for identifying patients with nutrition-related risk of all-cause and cardiovascular disease.Kidney Blood Press Res 2018;43:1878 –1889 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Efficacy and Safety of Agents in IgA Nephropathy: An Update Network Meta-Analysis
Conclusion: RASi combined with steroid demonstrated the most effective therapeutic approach for IgA nephropathy patients in terms of reducing proteinuria and stabilizing renal function.Kidney Blood Press Res 2018;43:1890 –1897 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Bioinformatic Analyses of Renal Ischaemia-Reperfusion Injury Models: Identification of Key Genes Involved in the Development of Kidney Disease
Conclusion:Timp1,Spp1,Dmgdh, miR-142-5p and miR-181a may be potential targets or biomarkers for the development of renal IRI.Kidney Blood Press Res 2018;43:1898 –1907 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Impact of Self-Report and eGFR-Based Chronic Kidney Disease on the Risk of Chronic Kidney Disease-Related Complications and Geriatric Syndromes in Community-Dwelling Older Adults
Conclusion: Among older adults, self-reported CKD may not be a surrogate for laboratory-diagnosed CKD and has an independent effect on CKD-related complications.Kidney Blood Press Res 2018;43:1908 –1918 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research

Immediate and Late Effects of Stress on Kidneys of Prepubertal and Adult Rats
Conclusion: Chronic stress induced before and after puberty led to irreversible glomerular loss, however, renal impairment was interrupted by removal of the stress stimuli.Kidney Blood Press Res 2018;43:1919 –1926 (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - December 19, 2018 Category: Urology & Nephrology Source Type: research