Post-mortem CMR in a model of sudden death due to myocardial ischemia: validation with connexin-43
ConclusionPM-CMR can reliably detect early signs of myocardial damage induced by ischemia, based on conventional pulse sequences complemented by a novel ad hoc application of quantitative mapping techniques.Key Points• Post-mortem MRI may help to understand cause of sudden cardiac death.• Post-mortem MRI allows detection of signs of myocardial ischemia as cause of sudden cardiac death within 90 and 40 min following coronary occlusion as demonstrated in a pig model of myocardial ischemia.• Signs of myocardial ischemia using conventional and mapping MRI technique are associated with the immunohistochemical cha...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Different phenotypes of neuropsychiatric systemic lupus erythematosus are related to a distinct pattern of structural changes on brain MRI
ConclusionWe showed that different phenotypes of NPSLE were related to distinct patterns of underlying structural brain MRI changes. Especially the inflammatory phenotype of NPSLE was associated with the most pronounced brain volume changes, which might facilitate the diagnostic process in SLE patients with neuropsychiatric symptoms.Key Points• Neuropsychiatric systemic lupus erythematosus (NPSLE) patients showed a higher WMH volume compared to SLE patients with neuropsychiatric syndromes not attributed to SLE (non-NPSLE).• NPSLE patients with inflammatory phenotype showed a lower total brain and white matter vol...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

A machine learning approach to distinguish between knees without and with osteoarthritis using MRI-based radiomic features from tibial bone
ConclusionOur results suggest that radiomic features are useful imaging biomarkers of subchondral bone for the diagnosis of osteoarthritis. An advantage of assessing bone on MRI instead of on radiographs is that other tissues can be assessed simultaneously.Key Points• Subchondral bone plays a role in the osteoarthritis disease processes.• MRI radiomics is a potential method for quantifying changes in subchondral bone.• Semi-automatically extracted radiomic features of tibia differ between subjects without and with osteoarthritis. (Source: European Radiology)
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Comparisons between image quality and diagnostic performance of 2D- and breath-hold 3D magnetic resonance cholangiopancreatography at 3T
ConclusionBreath-hold 3D MRCP with GRASE or CS can provide better image quality than 2D MRCP in a comparable scan time.Key Points• Breath-hold 3D MRCP using compressed sensing (CS) or gradient and spin-echo (GRASE) provided a better image quality with less image blurring than 2D MRCP.• There were no significant differences between 2D MRCP and breath-hold 3D MRCP in either motion artifact or the number of non-diagnostic exams.• There were no significant differences between 2D MRCP and either type of breath-hold 3D MRCP in the diagnosis of bile duct anatomic variation or detection of pancreatic lesions. (Sourc...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Interventional radiologists have a higher rate of chromosomal damage due to occupational radiation exposure: a dicentric chromosome assay
ConclusionsOur findings suggest that interventional radiologists had greater chromosomal damages than those in other occupational groups, and their partial-body exposure levels might be high enough to cause local damage. Use of special dosimeters to monitor partial-body exposure, as well as restricting the time and frequency of interventional procedures, could help reduce occupational radiation exposure.Key Points• Interventional radiologists had a higher number of dicentrics than the normal population and industrial radiographers.• The level of partial-body exposure of interventional radiologists might be high e...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Radiomics-based differentiation between glioblastoma and primary central nervous system lymphoma: a comparison of diagnostic performance across different MRI sequences and machine learning techniques
ConclusionRadiomics-based predictive accuracy can vary considerably, based on the model and feature selection methods as well as the combination of sequences used. Also, models derived from limited sequences show performance comparable to those derived from all five sequences.Key Points•Radiomics-based diagnostic performance of various machine learning models for differentiating glioblastoma and PCNSL varies considerably.•ML models using limited or multiple MRI sequences can provide comparable performance, based on the chosen model.•Embedded feature selection models perform better than models using a priori ...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Effect of curve location on the severity index for adolescent idiopathic scoliosis: a longitudinal cohort study
ConclusionsIn this multicentric cohort of 205 patients, the severity index was used to predict the risk of progression from mild to moderate scoliosis, with similar results of typical major curve types. This index represents a novel tool to aid the clinician and the patient in the modulation of the follow-up and, for progressive patients, their decision for brace treatment.Key Points•The severity index of adolescent idiopathic scoliosis has the potential to detect patients with progressive scoliosis as early as the first exam.•Out of 205 patients, 82% were correctly classified as either stable or progressive by t...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients
AbstractObjectivesTo compare the diagnostic performance of [18F]FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients.Material and methodsA cohort of 154 therapy-naive patients with newly diagnosed, histopathologically proven breast cancer was enrolled in this study prospectively. All patients underwent a whole-body [18F]FDG PET/MRI, computed tomography (CT) scan, and a bone scintigraphy prior to therapy. All datasets were evaluated regarding the presence of bone metastases. McNemarχ2 test was performed to compare sensitivity and specif...
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Editorial comment: advances in the evaluation of liver imaging and function with gadoxetic acid –enhanced MRI
(Source: European Radiology)
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Variation in CT perfusion protocol has implications on defining irreversibly damaged ischemic brain parenchyma
Key Points•Computed tomographic perfusion (CTP) is increasingly being used in the characterization of brain ischemia.•Variations in post-processing protocols continue to be a challenge, resulting in a slight variation of CTP results.•We need to adopt a universal acquisition protocol to help optimize output of CTP. (Source: European Radiology)
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Correction to: Evaluation of a convolutional neural network for ovarian tumor differentiation based on magnetic resonance imaging
A Correction to this paper has been published:https://doi.org/10.1007/s00330-021-07854-5 (Source: European Radiology)
Source: European Radiology - October 18, 2021 Category: Radiology Source Type: research

Sources of variation in multicenter rectal MRI data and their effect on radiomics feature reproducibility
AbstractObjectivesTo investigate sources of variation in a multicenter rectal cancer MRI dataset focusing on hardware and image acquisition, segmentation methodology, and radiomics feature extraction software.MethodsT2W and DWI/ADC MRIs from 649 rectal cancer patients were retrospectively acquired in 9 centers. Fifty-two imaging features (14 first-order/6 shape/32 higher-order) were extracted from each scan using whole-volume (expert/non-expert) and single-slice segmentations using two different software packages (PyRadiomics/CapTk). Influence of hardware, acquisition, and patient-intrinsic factors (age/gender/cTN-stage) o...
Source: European Radiology - October 16, 2021 Category: Radiology Source Type: research

Unilateral axillary adenopathy induced by COVID-19 vaccine: US follow-up evaluation
This study was conducted in order to investigate COVID-19 vaccine influence on unilateral axillary lymph nodes, comparing nodal basal features with their characteristics after the first and second vaccination dose.MethodsNinety-one volunteer employees from our center who participated in the BNT162b2 (Pfizer-BioNTech) vaccination campaign were prospectively recruited. A total of three axillary ultrasound evaluations of the ipsilateral vaccinated arm were performed: before vaccination, the week after the first dose and the week after the second dose. The following findings were recorded: the total number of visible nodes, th...
Source: European Radiology - October 16, 2021 Category: Radiology Source Type: research

Registration-based semi-automatic assessment of aortic diameter growth rate from contrast-enhanced computed tomography outperforms manual quantification
ConclusionsRegistration-based assessment of aortic dilation on CTA is accurate and substantially more reproducible than the current standard, even at follow-up as short as 6  months, and provides robust 3D mapping of aortic diameters and growth rates beyond the pre-established anatomic landmarks.Key Points•Registration-based semi-automatic assessment of progressive aortic dilation on CTA is accurate and substantially more reproducible than the current standard.•The registration-based technique allows robust growth rate assessment at follow-up as short as 6  months, with a similar reproducibility to that...
Source: European Radiology - October 16, 2021 Category: Radiology Source Type: research

Development and validation of a preoperative CT-based radiomic nomogram to predict pathology invasiveness in patients with a solitary pulmonary nodule: a machine learning approach, multicenter, diagnostic study
ConclusionsThis study demonstrated that a nomogram constructed by identified clinical –radiological signatures and combined radiomic signatures has the potential to precisely predict pathology invasiveness.Key Points• The radiomic signature from the perinodular area has the potential to predict pathology invasiveness of the solitary pulmonary nodule.• The new radiomic nomogram was useful in clinical decision-making associated with personalized surgical intervention and therapeutic regimen selection in patients with early-stage non-small-cell lung cancer. (Source: European Radiology)
Source: European Radiology - October 16, 2021 Category: Radiology Source Type: research

MRI-based radiomics signature and clinical factor for predicting H3K27M mutation in pediatric high-grade gliomas located in the midline of the brain
AbstractObjectiveTo develop a nomogram based on MRI radiomics and clinical features for preoperatively predicting H3K27M mutation in pediatric high-grade gliomas (pHGGs) with a midline location of the brain.MethodsThe institutional database was reviewed to identify patients with pHGGs with a midline location of the brain who underwent tumor biopsy with preoperative MRI scans between June 2016 and June 2021. A total of 107 patients with pHGGs, including 79 patients with H3K27M mutation, were consecutively included and randomly divided into training and test sets. Radiomics features were extracted from fluid-attenuated inver...
Source: European Radiology - October 16, 2021 Category: Radiology Source Type: research

Deep learning radiomics of ultrasonography can predict response to neoadjuvant chemotherapy in breast cancer at an early stage of treatment: a prospective study
ConclusionsThe proposed DLRP strategy holds promise for effectively predicting NAC response at its early stage for BC patients.Key Points• We proposed two novel deep learning radiomics (DLR) models to predict response to neoadjuvant chemotherapy (NAC) in breast cancer (BC) patients based on US images at different NAC time points.• Combining two DLR models, a deep learning radiomics pipeline (DLRP) was proposed for stepwise prediction of response to NAC.• The DLRP may provide BC patients and physicians with an effective and feasible tool to predict response to NAC at an early stage and to determine further pe...
Source: European Radiology - October 15, 2021 Category: Radiology Source Type: research

Analysis of mammograms using artificial intelligence to predict response to neoadjuvant chemotherapy in breast cancer patients: proof of concept
ConclusionsOur study describes an AI platform using baseline DM to predict BC patients ’ responses to NACT. The initial AI performance indicated the potential to aid in clinical decision-making. In order to continue exploring the clinical utility of AI in predicting responses to NACT for BC, further research, including refining the methodology and a larger sample size, is warranted .Key Points• We aimed to answer the following question: Prior to initiation of neoadjuvant chemotherapy, can artificial intelligence (AI) applied to digital mammograms (DM) predict breast tumour response?• DMs contain inform...
Source: European Radiology - October 15, 2021 Category: Radiology Source Type: research

Structured reporting in radiology: a systematic review to explore its potential
ConclusionThe level of evidence for implementing SR in radiology is still low and outcomes should be interpreted with caution.Key Points• Structured reporting is increasingly being used in radiology, especially in abdominal and neuroradiological CT and MRI reports.• SR can be subdivided into structured layout (SR level 1) and structured content (SR level 2), in which the first is defined as being a template in which the reporter has to report; the latter is an IT-based manner in which the content of the radiology report can be inserted and displayed into th e report.• Despite the extensive amount of research...
Source: European Radiology - October 15, 2021 Category: Radiology Source Type: research

Commentary on “Signal intensity ratio of draining vein on silent MR angiography as an indicator of high-flow arteriovenous shunt in brain arteriovenous malformation”
(Source: European Radiology)
Source: European Radiology - October 15, 2021 Category: Radiology Source Type: research

Minimally invasive removal of deep contraceptive implants under continuous ultrasound guidance is effective, quick, and safe
ConclusionsMinimally invasive removal of deep contraceptive implants under continuous ultrasound guidance alone is feasible, effective, and safe. In the present cohort, all implants were successfully removed, whatever the location, with short procedural time, small incision size, low pain levels, and no significant complications. This procedure could become a gold standard in this indication.Key Points• Minimally invasive removal of deep contraceptive implants under continuous ultrasound guidance alone is feasible, which led to a success rate of 100% whatever the location (even close to neurovascular structures), with...
Source: European Radiology - October 14, 2021 Category: Radiology Source Type: research

[18F]FDG PET/MRI and magnetoencephalography may improve presurgical localization of temporal lobe epilepsy
AbstractObjectivesTo evaluate the clinical value of the combination of [18F]FDG PET/MRI and magnetoencephalography (MEG) ([18F]FDG PET/MRI/MEG) in localizing the epileptogenic zone (EZ) in temporal lobe epilepsy (TLE) patients.MethodsSeventy-three patients with localization-related TLE who underwent [18F]FDG PET/MRI and MEG were enrolled retrospectively. PET/MRI images were interpreted by two radiologists; the focal hypometabolism on PET was identified using statistical parametric mapping (SPM). MEG spike sources were co-registered onto T1-weighted sequence and analyzed by Neuromag software. The clinical value of [18F]FDG ...
Source: European Radiology - October 14, 2021 Category: Radiology Source Type: research

Correction to: Combined hepatocellular-cholangiocarcinoma: can we use contrast-enhanced ultrasound Liver Imaging Reporting and Data System (LI-RADS) to predict the patient ’s survival?
(Source: European Radiology)
Source: European Radiology - October 14, 2021 Category: Radiology Source Type: research

Comparison of HU histogram analysis and BMD for proximal femoral fragility fracture assessment: a retrospective single-center case –control study
AbstractObjectivesTo evaluate the feasibility of HU histogram analysis (HUHA) to assess proximal femoral fragility fractures with respect to BMD.MethodsThis retrospective study included 137 patients with femoral fragility fractures who underwent hip CT and 137 control patients without fractures who underwent abdominal CT between January 2018 and February 2019. HUHA was calculated with the 3D volume of interest from the femoral head to the lesser trochanter. HUHAfat (percentage of negative HU values) and HUHAbone (percentage of HU values  ≥ 125 HU) were assumed to be fat and bone components, respectively. S...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Added-value of dynamic contrast-enhanced MRI on prediction of tumor recurrence in locally advanced cervical cancer treated with chemoradiotherapy
AbstractObjectivesTo evaluate whether the DCE-MRI derived parameters integrated into clinical and conventional imaging variables may improve the prediction of tumor recurrence for locally advanced cervical cancer (LACC) patients following concurrent chemoradiotherapy (CCRT).MethodsBetween March 2014 and November 2019, 79 consecutive LACC patients who underwent pelvic MRI examinations with DCE-MRI sequence before treatment were prospectively enrolled. The primary outcome was disease-free survival (DFS). DCE-MRI derived parameters, conventional imaging, and clinical factors were collected. Univariate and multivariate Cox haz...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Prediction of recurrence after surgery based on preoperative MRI features in patients with pancreatic neuroendocrine tumors
ConclusionMRI features, including size, enhancement pattern, vascular invasion, and ductal dilatation, are useful in predicting recurrence and poor DFS after surgery in PNET.Key Points•MRI features are useful for predicting prognosis in patients with PNET after surgery.•PV or SMV invasion (OR 10.49 [1.35 –81.64], p = 0.04) was significantly associated with 1-year recurrence.•Portal phase iso- to hypoenhancement (HR 21.36), CBD or MPD dilatation (HR 5.22), arterial invasion (HR 42.90), and larger size (HR 1.04) had significant effects on poor DFS (p 
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Predicting the molecular subtype of breast cancer and identifying interpretable imaging features using machine learning algorithms
ConclusionsThis study established an interpretable machine learning model to differentiate between breast cancer molecular subtypes, providing additional values for radiologists.Key Points•Interpretable machine learning model (MLM) could help clinicians and radiologists differentiate between breast cancer molecular subtypes.•The Shapley additive explanations (SHAP) technique can select important features for predicting the molecular subtypes of breast cancer from a large number of imaging signs.•Machine learning model can assist radiologists to evaluate the molecular subtype of breast cancer to some extent. ...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Impact of the COVID-19 lockdown in France on the diagnosis and staging of breast cancers in a tertiary cancer centre
ConclusionThe COVID-19 lockdown was associated with a 20% decrease in the number of diagnosed breast cancers. Because of delayed diagnosis, breast cancers detected after the lockdown had poorer prognosis with bigger tumour sizes and higher rates of node invasion.Key Points•The number of breast cancer diagnosed in a large tertiary cancer centre in France decreased by 20% during the first COVID-19 lockdown.•Because of delayed diagnosis, breast cancers demonstrated bigger tumour size and more frequent axillary lymph node invasion after the lockdown.•In case of a new lockdown, breast screening programme and foll...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

In-patient care trends in peripheral artery disease in the German healthcare system over the past decade
ConclusionsThis decade-long nationwide analysis shows a rising number of hospitalizations due to PAD with more comorbid patients resulting in increasing reimbursement costs. Interventions are shifting from surgical to endovascular approaches with a notable trend towards interventions in smaller vessels below the knee.Key Points• The number of hospitalizations due to peripheral artery disease is rising and it is associated with increasing reimbursement costs.• Admitted patients are older and show an increasing number of comorbidities while overall in-hospital mortality is decreasing.• Revascularization proced...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Response prediction of neoadjuvant chemoradiation therapy in locally advanced rectal cancer using CT-based fractal dimension analysis
ConclusionFD on pretreatment CT is a promising parameter for predicting pCR to nCRT in patients with LARC and could be used to help make treatment decisions.Key Points•Fractal dimension analysis on pretreatment CT was associated with response to neo-adjuvant chemoradiation in patients with locally advanced rectal cancer.•Fractal dimension is a promising biomarker for predicting pCR to nCRT and may potentially select patients for individualized therapy. (Source: European Radiology)
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Comparison of 7  T and 3 T vessel wall MRI for the evaluation of intracranial aneurysm wall
AbstractObjectivesTo compare the visibility of intracranial aneurysm wall and thickness quantification between 7 and 3  T vessel wall imaging and evaluate the association between aneurysm size and wall thickness.MethodsTwenty-nine patients with 29 unruptured intracranial aneurysms were prospectively recruited for 3D T1-weighted vessel wall MRI at both 3  T and 7 T with 0.53 mm (3 T) and 0.4 mm (7 T) isotropic resolution, respectively. Two neuroradiologists independently evaluated wall visibility (0–5 Likert scale), quantified the apparent wall thickness (AWT) using a semi-automated ...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

A deep learning –based automatic analysis of cardiovascular borders on chest radiographs of valvular heart disease: development/external validation
This study aimed to develop and validate a deep learning –based automatic CXR CB analysis algorithm (CB_auto) for diagnosing and quantitatively evaluating valvular heart disease (VHD).MethodsWe developed CB_auto using 816 normal and 798 VHD CXRs. For validation, 640 normal and 542 VHD CXRs from three different hospitals and 132 CXRs from a public dataset were assigned. The reliability of the CB parameters determined by CB_auto was evaluated. To evaluate the differences between parameters determined by CB_auto and manual CB drawing (CB_hand), the absolute percentage measurement error (APE) was calculated. Pearson corr...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Magnetic resonance imaging before breast cancer surgery: results of an observational multicenter international prospective analysis  (MIPA)
AbstractObjectivesPreoperative breast magnetic resonance imaging (MRI) can inform surgical planning but might cause overtreatment by increasing the mastectomy rate. The Multicenter International Prospective Analysis (MIPA) study investigated this controversial issue.MethodsThis observational study enrolled women aged 18 –80 years with biopsy-proven breast cancer, who underwent MRI in addition to conventional imaging (mammography and/or breast ultrasonography) or conventional imaging alone before surgery as routine practice at 27 centers. Exclusion criteria included planned neoadjuvant therapy, pregnancy, persona...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry
The objective of this study is to generate DRLs and median doses for these indications using data from the UCSF CT  International Dose Registry.MethodsStandardized data on 3.7 million CTs in adults were collected between 2016 and 2019 from 161 institutions across seven countries (United States of America (US), Switzerland, Netherlands, Germany, UK, Israel, Japan). DRLs (75th percentile) and median doses for volumetric CT-dose index (CTDIvol) and dose-length product (DLP) were assessed for each EUCLID category (chronic sinusitis, stroke, cervical spine trauma, coronary calcium scoring, lung cancer, pulmonary embolism, ...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Infratentorial lesions in multiple sclerosis patients: intra- and inter-rater variability in comparison to a fully automated segmentation using 3D convolutional neural networks
ConclusionThe performance of the CNN improved significantly for infratentorial lesions when specifically trained on infratentorial lesions using a T1 image as an additional input and matches the detection performance of experienced raters. Furthermore, for infratentorial lesions the CNN was more robust against repeated scans than experienced raters.Key Points•A 3D convolutional neural network was trained on MRI data from 1809 patients (156 different scanners) for the quantification of supratentorial and infratentorial multiple sclerosis lesions.•Inter-rater variability was higher for infratentorial lesions than f...
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Multiparametric quantitative MRI for the evaluation of dysthyroid optic neuropathy
AbstractObjectiveTo evaluate the ability of quantitative MRI parameters for predicting dysthyroid optic neuropathy (DON).MethodsWe retrospectively collected and analyzed the clinical features and 3.0  T MRI data of 59 patients with Graves orbitopathy (GO), with (n = 26) and without DON (n = 33). We compared MRI quantitative parameters, including the modified muscle index (mMI), proptosis, volume of intra-orbital fat, mean apparent diffusion coefficient value, and T2 value of the optic nerve among patients with and without DON. A logistic regression analysis was performed to iden tify the ri...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Multiparametric magnetic resonance imaging-derived radiomics for the prediction of disease-free survival in early-stage squamous cervical cancer
ConclusionMultiparametric MRI-derived radiomics based on multi-scale tumor region can aid in the prediction of DFS for ESSCC patients, thereby facilitating clinical decision-making.Key Points•Three radiomics scores based on multi-scale tumor region all showed favorable performances in DFS prediction. Rad-score (VOI+5  mm) performed best with favorable C-index values.•Combined model incorporating multiparametric MRI-based radiomics with clinical risk factors performed significantly better in DFS prediction than the clinical model.•Combined model presented as a nomogram can be easily used to predict survi...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Osteomyelitis on MR imaging as a key predictor of recurrent septic arthritis of the shoulder
AbstractObjectivesTo investigate the clinical and radiologic predictors of postoperative recurrent septic arthritis of the shoulder (SAS) using multivariable analysis.MethodsForty-three patients (mean age, 65  years; 24 women) who underwent surgery for SAS between January 2011 and October 2019 were retrospectively enrolled. An orthopedic surgeon assessed clinical (age, sex, comorbidity, duration from symptom onset to MR imaging and surgery, surgical method, antibiotic usage), laboratory (serum white blo od cell [WBC] count, C-reactive protein [CRP] level, synovial cell count), and surgical findings (culture/biopsy res...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Histogram analysis of diffusion-weighted imaging and dynamic contrast-enhanced MRI for predicting occult lymph node metastasis in early-stage oral tongue squamous cell carcinoma
ConclusionsWhole-tumor histogram analysis of ADC and wash-in maps is a feasible tool for preoperative evaluation of cervical node status in early-stage OTSCC.Key Points• Histogram analysis of parametric maps from DWI and DCE-MRI may assist the prediction of occult LNM in early-stage OTSCC.• ADC10th, ADCuniformity, and wash-inskewness were independent predictors.• The combined model exhibited good predictive performance, with an accuracy of 0.82. (Source: European Radiology)
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Diffusion kurtosis imaging and dynamic contrast-enhanced MRI for the differentiation of parotid gland tumors
AbstractObjectiveTo assess the usefulness of combined diffusion kurtosis imaging (DKI) and dynamic contrast-enhanced MRI (DCE-MRI) in the differentiation of parotid gland tumors.MethodsSeventy patients with 80 parotid gland tumors who underwent DKI and DCE-MRI were retrospectively enrolled and divided into four groups: pleomorphic adenomas (PAs), Warthin tumors (WTs), other benign tumors (OBTs), and malignant tumors (MTs). DCE-MRI and DKI quantitative parameters were measured. The Kruskal –Wallis H test and post hoc test with Bonferroni correction and ROC curve were used for statistical analysis.ResultsWTs demonstrat...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Reduced magnetic resonance angiography signal intensity in the middle cerebral artery ipsilateral to severe carotid stenosis may be a practical index of high oxygen extraction fraction
ConclusionsThe combination of reduced MCA rSI and ipsilateral narrow MLD is a straightforward index of high wb-OEF.Key Points• The whole-brain OEF in patients with angiographic slow flow in the MCA ipsilateral to high-grade carotid stenosis was higher than in patients without it.• Independent determinants of MCA slow flow were MCA relative signal intensity (rSI) on MRA or minimal luminal diameter (MLD) of the carotid stenosis.• The wb-OEF was higher in patients with an MCA rSI ≤ 0.89 and ipsilateral MLD ≤ 1.06 mm than patients without this combination. (Source: European Radiology)
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Estimation of pancreatic fibrosis and prediction of postoperative pancreatic fistula using extracellular volume fraction in multiphasic contrast-enhanced CT
AbstractObjectiveTo investigate the diagnostic performance of the extracellular volume (ECV) fraction in multiphasic contrast-enhanced computed tomography (CE-CT) for estimating histologic pancreatic fibrosis and predicting postoperative pancreatic fistula (POPF).MethodsEighty-five patients (49 men; mean age, 69  years) who underwent multiphasic CE-CT followed by pancreaticoduodenectomy with pancreaticojejunal anastomosis between January 2012 and December 2018 were retrospectively included. The ECV fraction was calculated from absolute enhancements of the pancreas and aorta between the precontrast and equi librium-pha...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Fuhrman nuclear grade prediction of clear cell renal cell carcinoma: influence of volume of interest delineation strategies on machine learning-based dynamic enhanced CT radiomics analysis
ConclusionShape and first-order features extracted from UP  + EP images are better feature representations. Contour-focused VOI erosion by 2 mm or dilation by 4 mm within peritumor renal parenchyma exerts limited impact on discriminative performance. It provides a reference for segmentation tolerance in radiomics-based modeling for ccRCC nuclear gradi ng.Key Points•Lesion delineation uncertainties are tolerated within a VOI erosion range of 2  mm or dilation range of 4 mm within peritumor renal parenchyma for radiomics-based ccRCC nuclear grading.•Radiomics features extracted fro...
Source: European Radiology - October 12, 2021 Category: Radiology Source Type: research

Correction to: Reporting standards for primary sclerosing cholangitis using MRI and MR cholangiopancreatography: guidelines from MR Working Group of the International Primary Sclerosing Cholangitis Study Group
(Source: European Radiology)
Source: European Radiology - October 4, 2021 Category: Radiology Source Type: research

The MTA score —simple and reliable, the best for now?
(Source: European Radiology)
Source: European Radiology - October 2, 2021 Category: Radiology Source Type: research

Feature tracking myocardial strain analysis in patients with bileaflet mitral valve prolapse: relationship with LGE and arrhythmias
ConclusionsCMR-FT allowed identifying subtle myocardial deformation abnormalities in bMVP patients at risk of SVT-VF. LGE and MAD distance were associated with cVA.Key Points• CMR-FT allows identifying several subtle myocardial deformation abnormalities in bMVP patients, especially those involving the papillary muscle.• CMR-FT allows identifying subtle myocardial deformation abnormalities in bMVP patients at risk of SVT and VF.• In patients with bMVP, the stronger predictor of cVA is LGE (OR = 8.51; 95% CI 1.76, 41.28; p = 0.008), followed by MAD distance (OR = 1.25; 95% CI 1.02, 1.54; p = 0.03). (Source: European Radiology)
Source: European Radiology - September 21, 2021 Category: Radiology Source Type: research

Lesson by SARS-CoV-2 disease (COVID-19): whole-body CT angiography detection of “relevant” and “other/incidental” systemic vascular findings
ConclusionsVascular involvement is not negligible in COVID-19 and should be carefully investigated as it may significantly affect disease behavior and prognosis.Key Points• Relevant vascular events were recorded in 71.4% of the study population, with pulmonary embolism being the most frequent event in ICU and non-ICU cases.• Apart from the lung, other organs such as the gut, spleen, liver, brain, and kidneys were involved with episodes of ischemic infarction. Systemic venous and arterial thrombosis occurred in 30.9% and 7.1% of cases, respectively, with venous events being significantly higher in ICU patients (p ...
Source: European Radiology - September 21, 2021 Category: Radiology Source Type: research

Improved detection of in-transit metastases of malignant melanoma with BSREM reconstruction in digital [18F]FDG PET/CT
AbstractObjectivesTo compare block sequential regularized expectation maximization (BSREM) and ordered subset expectation maximization (OSEM) for the detection of in-transit metastasis (ITM) of malignant melanoma in digital [18F]FDG PET/CT.MethodsWe retrospectively analyzed a cohort of 100 [18F]FDG PET/CT scans of melanoma patients with ITM, performed between May 2017 and January 2020. PET images were reconstructed with both OSEM and BSREM algorithms. SUVmax, target-to-background ratio (TBR), and metabolic tumor volume (MTV) were recorded for each ITM. Differences in PET parameters were analyzed with the Wilcoxon signed-ra...
Source: European Radiology - September 21, 2021 Category: Radiology Source Type: research

Incidence and factor analysis of laryngohyoid fractures in hanging individuals —computed tomography study
AbstractObjectivesAlthough laryngohyoid fracture indicates the applied neck pressure and is an important finding in hanging individuals, the reported rate varies widely and its true incidence remains controversial. We used computed tomography (CT) studies to investigate the incidence of laryngohyoid fracture in hanging individuals and identify factors contributing to such fractures.MethodsConsidered for inclusion in this study were 107 attempted or successful hanging individuals subjected to CT studies between 2005 and 2019. After excluding 19 whose images were inadequate for evaluation, 88 subjects were included. Body sus...
Source: European Radiology - September 21, 2021 Category: Radiology Source Type: research

Assessment of factors affecting washout appearance of hepatocellular carcinoma on CT
AbstractObjectivesTo identify independent imaging and histopathologic factors that affect washout appearance of hepatocellular carcinoma (HCC) in CT images.MethodsThis retrospective study included 264 patients who had undergone surgical resection for treatment-na ïve single HCC between January 2014 and December 2015 and had available preoperative multiphasic CT images. Two reviewers evaluated the CT imaging features of HCC using LI-RADS v2018. The “washout” was visually assessed in portal venous or equilibrium phases. Depending on the presence of washou t appearance of HCC, all patients were divided into &...
Source: European Radiology - September 21, 2021 Category: Radiology Source Type: research