Fully automated AI-based splenic segmentation for predicting survival and estimating the risk of hepatic decompensation in TACE patients with HCC
ConclusionAutomated SV assessments showed superior survival predictions in patients with HCC undergoing TACE compared to two-dimensional spleen size estimates and identified patients at risk of hepatic decompensation. Thus, SV could serve as an automatically available, currently underappreciated imaging biomarker.Key Points• Splenic volume is a relevant prognostic factor for prediction of survival in patients with HCC undergoing TACE, and should be preferred over two-dimensional surrogates for splenic size.• Besides overall survival, progression-free survival and hepatic decompensation were significantly associated wit...
Source: European Radiology - April 8, 2022 Category: Radiology Source Type: research

A preliminary coronary computed tomography angiography –based study of perivascular fat attenuation index: relation with epicardial adipose tissue and its distribution over the entire coronary vasculature
ConclusionThe perivascular FAI was significantly higher than EAT density and correlated substantially with EAT density. The perivascular FAI distribution over the entire coronary tree varied and prompted for vessel-specific or segment-specific thresholds to determine abnormal perivascular FAI in practice.Key Points•The perivascular FAI correlated well with EAT density and had higher values than EAT density.•The distributions of perivascular FAI differ between coronary vessels or segments; considering segment and vessel confounding factors while conducting a perivascular FAI study is necessary.•No significant differen...
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

Liver imaging: it is time to adopt standardized terminology
AbstractLiver imaging plays a vital role in the management of patients at risk for hepatocellular carcinoma (HCC); however, progress in the field is challenged by nonuniform and inconsistent terminology in the published literature. The Steering Committee of the American College of Radiology (ACR) ’s Liver Imaging Reporting And Data System (LI-RADS), in conjunction with the LI-RADS Lexicon Writing Group and the LI-RADS International Working Group, present this consensus document to establish a single universal liver imaging lexicon. The lexicon is intended for use in research, education, an d clinical care of patients at ...
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

Feasibility of an accelerated 2D-multi-contrast knee MRI protocol using deep-learning image reconstruction: a prospective intraindividual comparison with a standard MRI protocol
ConclusionTSEDL of the knee is clinically feasible, showing excellent image quality and equivalent diagnostic performance compared to TSES, reducing the acquisition time about 50%.Key Points• Deep-learning reconstructed TSE imaging is able to almost halve the acquisition time of a three-plane knee MRI with proton density and T1-weighted images, from 11:56 min to 6:11 min at 3 T.• Deep-learning reconstructed TSE imaging of the knee provided significant improvement of noise levels (p<  0.001), providing higher image quality (p< 0.05) compared to conventional TSE imaging.• Deep-learning reconstructed TSE imaging ...
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

Development and validation of a combined nomogram model based on deep learning contrast-enhanced ultrasound and clinical factors to predict preoperative aggressiveness in pancreatic neuroendocrine neoplasms
ConclusionsThe combined nomogram model could serve as a preoperative, noninvasive, and precise evaluation tool to differentiate aggressive and non-aggressive PNENs.Key Points• Tumor size (odds ratio [OR], 1.58; p = 0.02), arterial enhancement level (OR, 0.04; p = 0.008), and deep learning predictive probability (OR, 288.46; p< 0.001) independently predicted aggressiveness of pancreatic neuroendocrine neoplasms preoperatively.• The combined model predicted aggressiveness better than the clinical model (AUC: 0.97 vs. 0.87, p = 0.009), achieving AUC values of 0.97 and 0.85 in the training set and the test set, respecti...
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

Two-dimensional CT measurements enable assessment of body composition on head and neck CT
ConclusionsBody composition information can be obtained with comparable reliability from head and neck CT using simple biplanar measurements as from abdominal CT.Key Points•The total paraspinal muscle area at the height of C3 and C5 correlates strongly with abdominal muscle mass.•The total cross-sectional area at the submandibular level and at the height of C3 shows good correlations with abdominal fat mass.•The described measurements facilitate a rapid, opportunistic assessment of relevant body composition parameters. (Source: European Radiology)
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

CT-monitored minimal ablative margin control in single-session microwave ablation of liver tumors: an effective strategy for local tumor control
ConclusionsIn MWA of liver tumors, intra-procedural CECT monitoring of minimal ablative margin facilitates identification of potentially suboptimal margins and guides immediate additional intra-session ablation to maximize rates of margin-sufficient ablations, the latter being a highly predictive marker for excellent long-term local tumor control.Key Points• In MWA of liver tumors, intra-procedural CECT can identify potentially suboptimal minimal ablative margin, leading to immediate additional ablation in a single treatment session.• Achieving a finally sufficient ablative margin through the MWA with intra-procedural ...
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

Ultrasound-guided continuous radiofrequency ablation of the suprascapular nerve for chronic shoulder pain secondary to osteoarthritis: a retrospective cohort study
ConclusionsUltrasound-guided CRF lesioning of the suprascapular nerve in the spinoglenoid notch is a safe treatment for chronic osteoarthritic shoulder pain, with repeat treatments infrequently required. It is associated with significant improvement in VAS pain scores.Key Points• Ultrasound-guided continuous radiofrequency lesioning of the suprascapular nerve in the spinoglenoid notch is a safe treatment for chronic shoulder pain in degenerative disease, with repeat treatments infrequently required.• The procedure is performed under ultrasound guidance, without the use of ionising radiation. (Source: European Radiology)
Source: European Radiology - April 7, 2022 Category: Radiology Source Type: research

FDG PET/CT radiomics as a tool to differentiate between reactive axillary lymphadenopathy following COVID-19 vaccination and metastatic breast cancer axillary lymphadenopathy: a pilot study
ConclusionRadiomics features can differentiate between FDG-avid breast cancer metastatic and FDG-avid COVID-19 vaccine –related axillary lymphadenopathy. Such a model may have a role in differentiating benign nodes from malignant ones.Key Points• Patients who were vaccinated with the COVID-19 mRNA vaccine have shown FDG-avid reactive axillary lymph nodes in PET-CT scans.• We evaluated if radiomics and machine learning can distinguish between FDG-avid metastatic axillary lymphadenopathy in breast cancer patients and FDG-avid reactive axillary lymph nodes.• Combined PET and CT radiomics data showed good test AUC (0.9...
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

Development and validation of MRI-based radiomics signatures models for prediction of disease-free survival and overall survival in patients with esophageal squamous cell carcinoma
ConclusionsWe demonstrated that a combined predictive model based on MR Rad-S and clinical risk factors had better predictive efficacy than the radiomics models alone for patients with ESCC.Key Points• Magnetic resonance–based radiomics features combined with clinical risk factors can predict survival in patients with ESCC.• The radiomics nomogram can be used clinically to predict patient recurrence, DFS, and OS.• Magnetic resonance imaging is highly reproducible in visualizing lesions and contouring the whole tumor. (Source: European Radiology)
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

Proposed diagnostic volumetric bone mineral density thresholds for osteoporosis and osteopenia at the cervicothoracic spine in correlation to the lumbar spine
ConclusionOur data show a high correlation between clinically used mean L1 –L3 values and vBMD values elsewhere in the spine, independent of age. The proposed cut-off values for the cervicothoracic spine therefore may allow the determination of low bone mass even in clinical cases where only parts of the spine are imaged.Key PointsvBMD of all cervicothoracic vertebrae showed strong correlation with lumbar vertebrae (L1 –L3), with a median Pearson’s correlation coefficient of r = 0.87 (range: rC2 =  0.76 to rT12 =  0.96).The correlation coefficients were significantly lower (p  <  0.0001) without ex...
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

A review on the added value of whole-body MRI in metastatic lobular breast cancer
AbstractInvasive lobular breast carcinomas (ILC) account for approximately 15% of breast cancer diagnoses. They can be difficult to diagnose both clinically and radiologically, due to their infiltrative growth pattern. The pattern of metastasis of ILC is unusual, with spread to the serosal surfaces (pleura and peritoneum), retroperitoneum and gastrointestinal (GI)/genitourinary (GU) tracts and a higher rate of leptomeningeal spread than IDC. Routine staging and response assessment with computed tomography (CT) can be undertaken quickly and measurements can be reproduced easily, but this is challenging with metastatic ILC a...
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

Microwave ablation versus parathyroidectomy for the treatment of primary hyperparathyroidism: a cohort study
ConclusionMWA and PTX have comparable clinical outcomes for pHPT. MWA has a shorter procedure time and smaller incision length.Key Points• There were no differences in terms of clinical cure, persistent pHPT, recurrent pHPT, or major complications between MWA and PTX in the treatment of pHPT.• MWA is minimally invasive and results in a shorter procedure time.• Multiple nodules and high levels of iPTH were the independent risk factors for recurrent and persistent pHPT. (Source: European Radiology)
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

Long-term outcomes of image-guided ablation and laparoscopic partial nephrectomy for T1 renal cell carcinoma
ConclusionsIGA is potentially as good as LPN in oncological durability. IGA preserves kidney function significantly better than LPN. More studies with larger sample size should be performed to establish IGA as a first-line treatment alongside LPN.Key Points•Ablative therapies are alternatives to partial nephrectomy for managing small renal cell carcinomas.•This study reports long-term outcomes of image-guided ablation versus partial nephrectomy.•Ablative therapies have comparable oncological durability and better renal function preservation compared to partial nephrectomy. (Source: European Radiology)
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research

Optimal time point of response assessment for predicting survival is associated with tumor burden in hepatocellular carcinoma receiving repeated transarterial chemoembolization
ConclusionsORR as surrogacy of OS is associated with tumor burden. For patients with low/intermediate tumor burden, initial ORR should be preferred in its early availability upon similar sensitivity, whereas for patients with high tumor burden, best ORR has optimal sensitivity. Timing of OR assessment should be tailored according to tumor burden.Key Points• This is the first study utilizing individual patient data to comprehensively analyze the surrogacy of ORR with a long follow-up period.• Optimal timing of ORR assessment for predicting survival should be tailored according to tumor burden.• For patients with low a...
Source: European Radiology - April 6, 2022 Category: Radiology Source Type: research