Correction to: Added-value of dynamic contrast-enhanced MRI on prediction of tumor recurrence in locally advanced cervical cancer treated with chemoradiotherapy
(Source: European Radiology)
Source: European Radiology - February 4, 2022 Category: Radiology Source Type: research

Looking critically at the paradigm of radiation exposure from multiple imaging examinations
(Source: European Radiology)
Source: European Radiology - February 3, 2022 Category: Radiology Source Type: research

CT-based radiomics for differentiating intracranial contrast extravasation from intraparenchymal haemorrhage after mechanical thrombectomy
ConclusionsThe radiomic signature constructed based on initial post-operative nonenhanced CT after mechanical thrombectomy can effectively differentiate IPH from iodinated contrast extravasation.Key Points•Radiomic features were extracted from intraparenchymal areas of hyperattenuation on initial post-operative CT scans after mechanical thrombectomy.•The nonenhanced CT-based radiomic signature can differentiate IPH from iodinated contrast extravasation early.•The radiomic signature may help prevent unnecessary rescanning after mechanical thrombectomy, especially in cases where contrast extravasation is highly suggest...
Source: European Radiology - February 3, 2022 Category: Radiology Source Type: research

Correction to: Diagnosis of cardiac amyloid transthyretin (ATTR) amyloidosis by early (soft tissue) phase [99mTc]Tc-DPD whole body scan: comparison with late (bone) phase imaging
(Source: European Radiology)
Source: European Radiology - February 3, 2022 Category: Radiology Source Type: research

Balancing the benefits and harms of MRI-directed biopsy pathways
Key Points• Before a prostate biopsy, the likely benefits and the harms emanating from true and false test MRI results need to be balanced. Prioritizing patients’ preferences and their tolerance to potential harms are essential to assess.• The decision curve analysis method is an analytical framework where the net clinical benefit is plotted against a range of risk thresholds of having important cancers, helping patients and their physicians to decide between cancer averse (important cancers being detected) and biopsy averse (biop sies avoided) strategies.• The decision curve analysis method showed that the incorpo...
Source: European Radiology - February 1, 2022 Category: Radiology Source Type: research

Magnetic resonance neurography: is it so complicated that it needs a touch of genius?
Key Points•Neuropathy imaging is not that complicated or illusive that it needs a touch of genius.• By gaining MR imaging expertise of peripheral nerve lesions and using knowledge of common clinical patterns and diseases, general radiology practitioners can prudently participate in the multidisciplinary care for appropriate and timely management of peripheral neuropathy patients. (Source: European Radiology)
Source: European Radiology - February 1, 2022 Category: Radiology Source Type: research

Editorial comment on “Automated quantitative lesion water uptake in acute stroke is a predictor of malignant cerebral edema”
Key Points• In patients with acute ischemic stroke, automated measurements of net water uptake in baseline CTA an NCCT scans can be used as predictor for developing malignant cerebral edema.• A creative approach can lead to broader usability of automated tools. (Source: European Radiology)
Source: European Radiology - February 1, 2022 Category: Radiology Source Type: research

Correlation of liver enhancement in gadoxetic acid –enhanced MRI with liver functions: a multicenter-multivendor analysis of hepatocellular carcinoma patients from SORAMIC trial
ConclusionsThe liver enhancement on the hepatobiliary phase of gadoxetic acid –enhanced MRI is correlated with biomarkers of liver functions in a multicenter cohort. However, this correlation shows variations between scanner brands.Key Points• The correlation between liver enhancement on the hepatobiliary phase of gadoxetic acid–enhanced MRI and liver function is consistent in a multicenter-multivendor cohort.• Signal intensity–based indices (liver-to-spleen ratio) can be used as an imaging biomarker of liver function.• However, absolute values might change between vendors. (Source: European Radiology)
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Virtual clinical trial to compare cancer detection using combinations of 2D mammography, digital breast tomosynthesis and synthetic 2D imaging
ConclusionsThis study demonstrated that masses were detected better with DBT than with DM alone and there was no significant difference (p = 0.075) in LDF between DM&DBT and SM&DBT for calcifications clusters. Our results support previous studies that it may be acceptable to not acquire digital mammography alongside tomosynthesis for subtle calcification clusters and ill-defined masses.Key Points•The detection of masses was significantly better using DBT than with digital mammography alone.•The detection of calcification clusters was not significantly different between digital mammography and synthetic 2D image...
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Inter-reader agreement of the PI-QUAL score for prostate MRI quality in the NeuroSAFE PROOF trial
ConclusionWe observed strong reproducibility in the assessment of PI-QUAL between two radiologists with high expertise in prostate mpMRI. At present, PI-QUAL offers clinicians the only available tool for evaluating and reporting the quality of prostate mpMRI in a systematic manner but further refinements of this scoring system are warranted.Key Points•Inter-reader agreement for each single Prostate Imaging Quality (PI-QUAL) score (i.e., PI-QUAL 1 to PI-QUAL 5) was strong, with weighted kappa = 0.85 (95% confidence intervals: 0.51 – 1) and percent agreement = 84%.• Interobserver  agreement was strong when the scans w...
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Imaging modalities for confirming pulmonary embolism during pregnancy: results from a multicenter international study
ConclusionCTPA was the primary modality for confirming PE in all trimesters of pregnancy, although its proportional use was higher in later stages of pregnancy.Key Points•Computed tomography pulmonary angiography (CTPA) was the primary modality of diagnosis in all trimesters of pregnancy among patients with confirmed pulmonary embolism, even in the first trimester.•From the first trimester of pregnancy to postpartum period, there was a linear increase in the proportion of patients with pulmonary embolism who were diagnosed based on CTPA.•In the postpartum period, use of CTPA as the modality to confirm pulmonary embol...
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Quantitative T2 mapping of the sacroiliac joint cartilage at 3T in patients with axial spondyloarthropathies
ConclusionsT2 values of both active and inactive sacroiliac joint cartilages of SpA patients were increased. Thus, T2 mapping may be used in the diagnosis of SpA.Key Points•Sacroiliac cartilage T2 values of SpA patients increase compared to those of the non-SpA controls.•Sacroiliac cartilage T2 values of active and inactive joints of SpA patients increase compared to those of the non-SpA controls.•Sacroiliac cartilage T2 values of active and inactive joints of SpA patients do not show statistically significant difference. (Source: European Radiology)
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Liver stiffness measurement by magnetic resonance elastography is not affected by hepatic steatosis
ConclusionsIn patients with NAFLD, the severity of hepatic steatosis has no significant influence on the liver stiffness measurement with magnetic resonance elastography.Key Points• The MRI-based proton density fat fraction provides a quantitative assessment of hepatic steatosis with high accuracy.• No significant effect of hepatic steatosis on MRE-based liver stiffness measurement was found in patients with S1, S2, and S3 steatosis and between all steatosis grades after patients were grouped according to fibrosis stage.• After adjusting for fibrosis stage and age, there was no statistically significant relationship ...
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

Performance of radiomics models for tumour-infiltrating lymphocyte (TIL) prediction in breast cancer: the role of the dynamic contrast-enhanced (DCE) MRI phase
ConclusionThe DCE-MRI radiomics model, especially image features extracted from the delayed phases, can help improve the performance in predicting TILs. The radiomics nomogram is effective in predicting TILs in breast cancer.Key Points•Radiomics features extracted from DCE-MRI, especially delayed phase images, help predict TIL levels in breast cancer.•We developed a nomogram based on MRI to predict TILs in breast cancer that achieved the highest AUC of 0.950. (Source: European Radiology)
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research

PI-QUAL v.1: the first step towards good-quality prostate MRI
Key Points• It is mandatory to evaluate the image quality of a prostate MRI scan, and to mention this quality in the report.• PI-QUAL v1 is an essential starting tool to standardize the evaluation of the quality of prostate MR-images as objectively as possible.• PI-QUAL will step by step develop into a reliable quality assessment tool to ensure that the first step of the MRI pathway is as accurate as possible. (Source: European Radiology)
Source: European Radiology - January 27, 2022 Category: Radiology Source Type: research