Does the presence of macroscopic intralesional fat exclude malignancy? An analysis of 613 histologically proven malignant bone lesions
ConclusionMalignant lesions rarely contain macroscopic intralesional fat on CT or MRI. While CT is effective in detecting macroscopic intralesional fat in primarily lytic lesions, MRI may be better for the assessment of heterogenous and infiltrative lesions with mixed lytic and sclerotic components.Clinical relevance statementMacroscopic intralesional fat is rarely seen in malignant bone tumors and its presence can help to guide the diagnostic workup of bone lesions.Key Points•Presence of macroscopic intralesional fat in bone lesions has been widely theorized as a sign of benignity, but there is limited supporting eviden...
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

MR-contrast enhanced mammography (CEM) for follow-up of breast cancer patients: a “pros and cons” debate
AbstractWomen with a personal history of breast cancer (PHBC) are at an increased risk of either a local recurrence or a new primary breast cancer. Thus, surveillance is essential for the detection of recurrent disease at the earliest possible stage, allowing for prompt treatment, and potentially improving overall survival. Nowadays, mammography follow-up is the only surveillance imaging technique recommended by international guidelines. Nevertheless, sensitivity of mammography is lower after breast cancer treatment, particularly during the first 5 years, due to increased density or post-treatment changes. Contrast-enhance...
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

High-performance presurgical differentiation of glioblastoma and metastasis by means of multiparametric neurite orientation dispersion and density imaging (NODDI) radiomics
ConclusionThe NODDI radiomics model showed promising performance for preoperative discrimination between Gb and SBM.Clinical relevance statementThe NODDI radiomics model showed promising performance for preoperative discrimination between Gb and SBM, and radiomics features can be incorporated into the multidimensional phenotypic features that describe tumor heterogeneity.Key Points•The neurite orientation dispersion and density imaging (NODDI) radiomics model showed promising performance for preoperative discrimination between glioblastoma and solitary brain metastasis.•Compared with other tumor volumes of interest, th...
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

Recommender-based bone tumour classification with radiographs —a link to the past
ConclusionOur novel approach surpasses current models in tumour classification and links to past patient data, leveraging expert insights.Clinical relevance statementThe proposed algorithm could serve as a vital support tool for clinicians and general practitioners with limited experience in bone tumour classification by identifying similar cases and classifying bone tumour entities.Key Points•Addressed accurate bone tumour classification using radiographic features.•Model achieved 92.86%, 92.86% and 34.08% mean accuracy, precision and recall, respectively, significantly surpassing state-of-the-art models.•Enhanced d...
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

Paris classification of colonic polyps using CT colonography: prospective cohort study of interobserver variation
ConclusionRadiologist agreement when using the Paris classification at CT colonography is low, and radiologist classification agrees poorly with colonoscopy. Using the full Paris classification in routine CTC reporting is of questionable value.Clinical relevance statementInterobserver agreement for radiologists using the Paris classification to categorise colorectal polyp morphology is only fair; routine use of the full Paris classification at CT colonography is questionable.Key Points• Overall interobserver agreement for the Paris classification at CT colonography (CTC) was only fair, and lower than for colonoscopy.• ...
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

ESR Bridges: imaging and treatment of hepatocellular carcinoma —a multidisciplinary view
(Source: European Radiology)
Source: European Radiology - March 15, 2024 Category: Radiology Source Type: research

Highest 3-month international normalized ratio (INR): a predictor of bleeding following ultrasound-guided liver biopsy
ConclusionThe highest INR in 3  months preceding ultrasound-guided percutaneous liver biopsy is associated with, and a better predictor for, post-procedural bleeding than the most recent INR and should be considered in patient risk stratification.Clinical relevance statementDespite correction of coagulopathic indices, the highest international normalized ratio within the 3  months preceding percutaneous liver biopsy is associated with, and a better predictor for, bleeding and should considered in clinical decision-making and determining biopsy approach.Key Points•Bleeding occurred in 2% of patients following ultrasound...
Source: European Radiology - March 14, 2024 Category: Radiology Source Type: research

Diagnostic performance of photon-counting detector CT for differentiation between adrenal adenomas and metastases
ConclusionVNC algorithms overestimate CT values compared to TNC in the assessment of adrenal lesions. However, they allow a reliable discrimination between adrenal adenomas and metastases and could be used in clinical routine in near future with an increased threshold (e.g., 26 HU). Further (multi-center) studies with larger patient cohorts and standardized protocols are required.Clinical relevance statementVNC reconstructions overestimate CT values compared to TNC. Using a different threshold (e.g., 26 HU compared to the established 10 HU), VNC has a high diagnostic accuracy for the discrimination between adrenal adenomas...
Source: European Radiology - March 14, 2024 Category: Radiology Source Type: research

Diagnostic efficacy of image-guided core needle biopsy of suspected malignant osseous lesions: pitfalls and factors affecting diagnostic yield
(Source: European Radiology)
Source: European Radiology - March 14, 2024 Category: Radiology Source Type: research

Left atrial strain in patients with β-thalassemia major: a cross-sectional CMR study
ConclusionIn patients with β-TM, LA strain parameters were impaired compared to control subjects, and they exhibited a significant correlation with the number of LV segments with LGE. Furthermore, patients with cardiac complications had impaired left atrial strain parameters.Clinical relevance statementIn patients with β-thalassemia major, left atrial strain parameters were impaired compared to control subjects and emerged as a sensitive marker of cardiac complications, stronger than cardiac iron levels.Key Points•Compared to healthy subjects, β-thalassemia major patients demonstrated significantly lower left atrial r...
Source: European Radiology - March 13, 2024 Category: Radiology Source Type: research

The quest for open datasets: all that glitters is not gold
(Source: European Radiology)
Source: European Radiology - March 13, 2024 Category: Radiology Source Type: research

The scientific system must bend to avoid breaking
(Source: European Radiology)
Source: European Radiology - March 13, 2024 Category: Radiology Source Type: research

Atrial and ventricular strain using cardiovascular magnetic resonance in the prediction of outcomes of pericarditis patients: a pilot study
ConclusionLA reservoir and conduit mechanisms on CMR are independently associated with a higher risk of adverse pericardial events. Including atrial strain parameters in the management of acute pericarditis may improve risk stratification.Clinical relevance statementAtrial strain could be a suitable non-invasive and non-contrast cardiovascular magnetic resonance parameter for predicting adverse pericardial complications in patients with acute pericarditis.Key Points•Myocardial strain is a well-validated CMR parameter for risk stratification in cardiovascular diseases.•LA reservoir and conduit functions are significantl...
Source: European Radiology - March 11, 2024 Category: Radiology Source Type: research

Reproducibility of artificial intelligence –enabled plaque measurements between systolic and diastolic phases from coronary computed tomography angiography
ConclusionExcellent  agreement and no substantial differences were observed in AI-enabled quantitative plaque measurements on CTA in systolic and diastolic images. Following further validation, standardized plaque measurements can be performed from CTA in systolic or diastolic cardiac phase.Clinical relevance statementQuantitative plaque assessment using artificial intelligence –enabled plaque analysis software can provide standardized plaque quantification, regardless of cardiac phase.Key Points• The impact of different cardiac phases on coronary plaque measurements is unknown.• Plaque analysis using artificial int...
Source: European Radiology - March 11, 2024 Category: Radiology Source Type: research

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation
ConclusionThe AI-assisted double reading system was able to identify missed findings on chest radiographs after report authorisation. The approach required an external radiologist to review the AI-detected discrepancies. The number of clinically relevant missed findings by radiologists was very low.Clinical relevance statementThe AI-assisted double reader workflow was shown to detect diagnostic errors and could be applied as a quality assurance tool. Although clinically relevant missed findings were rare, there is potential impact given the common use of chest radiography.Key Points• A commercially available double readi...
Source: European Radiology - March 11, 2024 Category: Radiology Source Type: research