A retrospective external validation study of the Birmingham Atypical Cartilage Tumour Imaging Protocol (BACTIP) for the management of solitary central cartilage tumours of the proximal humerus and around the knee
ConclusionAlthough promising as a useful tool for management/follow-up of CCTs of the proximal humerus, distal femur, and proximal tibia, five ACTs and one chondrosarcoma grade II were discharged, potentially inducing diagnostic delay, which could be reduced by adapting BACTIP cut-off values.Clinical relevance statementMostly, Birmingham Atypical Cartilage Tumour Imaging Protocol (BACTIP) assesses central cartilage tumours of the proximal humerus and the knee correctly. Both when using the BACTIP and when adapting cut-offs, caution should be taken for the trade-off between underdiagnosis/potential diagnostic delay in chond...
Source: European Radiology - February 6, 2024 Category: Radiology Source Type: research
Can digital breast tomosynthesis decrease interval cancers in a breast cancer screening program?
(Source: European Radiology)
Source: European Radiology - February 6, 2024 Category: Radiology Source Type: research
Radiomics in differential diagnosis of Wilms tumor and neuroblastoma with adrenal location in children
ConclusionIn conclusion, the CT-based clinic-radiologic-radiomics combined model could noninvasively predict WT or NB preoperatively. Notably, that model correctly predicted two patients, which none of the radiologists could correctly predict. This model may serve as a noninvasive preoperative predictor of NB/WT differentiation in CT, which should be further validated in large prospective models.Clinical relevance statementCT-based clinic-radiologic-radiomics combined model could noninvasively predict Wilms tumor or neuroblastoma preoperatively.Key Points•CT radiomics features can predict Wilms tumor or neuroblastoma fro...
Source: European Radiology - February 5, 2024 Category: Radiology Source Type: research
Key learning on the promise and limitations of MRI in prostate cancer screening
AbstractMRI retains its ability to reduce the harm of prostate biopsies by decreasing biopsy rates and the detection of indolent cancers in population-based screening studies aiming to find clinically significant prostate cancers. Limitations of low positive predictive values and high reader variability in diagnostic performance require optimisations in patient selection, imaging protocols, interpretation standards, diagnostic thresholds, and biopsy methods. Improvements in diagnostic accuracy could come about through emerging technologies like risk calculators and polygenic risk scores to select men for MRI. Furthermore, ...
Source: European Radiology - February 5, 2024 Category: Radiology Source Type: research
Scanxiety and quality of life around follow-up imaging in patients with unruptured intracranial aneurysms: a prospective cohort study
ConclusionsTwo-thirds of the respondents experienced scanxiety around follow-up imaging, which often resolved within a day after receiving results. Patients with scanxiety had similar HRQoL but worse emotional functioning compared to patients without scanxiety. The time between the scan and receiving the results should be minimized to decrease the duration of scanxiety.Clinical relevance statementWe showed that scanxiety is common in UIA patients, and negatively associated with emotional functioning. Since scanxiety often disappears immediately after receiving the radiology report, it should be communicated to the patient ...
Source: European Radiology - February 5, 2024 Category: Radiology Source Type: research
Prognostic implications of pre-transcatheter aortic valve replacement computed tomography-derived coronary plaque characteristics and stenosis severity
ConclusionsIn TAVR candidates, both CT-FFR and the presence of ≥ 3 HRPC were associated with an increased risk of adverse clinical events. However, the value of HRPC differed with the CT-FFR category, with more incremental predictability among vessels with negative CT-FFR but not among vessels with positive CT-FFR.Clinical relevance statementIn transcatheter aortic valve replacement (TAVR) candidates, pre-TAVR CTA provided the opportunity to assess coronary physiological stenosis severity and high-risk plaque characteristics, both of which are associated with worse clinical outcomes.Key Points•The current study inves...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Value of radiological depth of invasion in non-pT4 Oral tongue squamous cell carcinoma: implication for preoperative MR T-staging
ConclusionsrDOI is a critical predictor of OTSCC mortality and facilitates preoperative prognostic stratification, which should be considered in future oral subsite MR T-staging.Clinical relevance statementUtilizing axial CE-T1WI, an MR T-staging system for non-pT4 OTSCC was developed by employing rDOI measurement with optimal thresholds of 8  mm and 12 mm, which is comparable with pathological staging and merits consideration in future preoperative oral subsite planning.Key Points• Tumor morphology, measuring sequences, and observers could impact MR-derived measurements and compromise the consistency with histology.â€...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Current status of optoacoustic breast imaging and future trends in clinical application: is it ready for prime time?
AbstractOptoacoustic imaging (OAI) is an emerging field with increasing applications in patients and exploratory clinical trials for breast cancer. Optoacoustic imaging (or photoacoustic imaging) employs non-ionizing, laser light to create thermoelastic expansion in tissues and detect the resulting ultrasonic emission. By combining high optical contrast capabilities with the high spatial resolution and anatomic detail of grayscale ultrasound, OAI offers unique opportunities for visualizing biological function of tissues in vivo. Over the past decade, human breast applications of OAI, including benign/malignant mass differe...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Correlation of endolymphatic hydrops and perilymphatic enhancement with the clinical features of M énière’s disease
ConclusionThe EH grade and SIR (an indicator for the quantitative evaluation of PE) were correlated with clinical features and HT of MD; thus, imaging can be a valuable tool in planning individualised treatment.Clinical relevance statementThis study revealed that the grade of endolymphatic hydrops and degree of perilymphatic enhancement positively correlates with the length of time since onset of clinical symptoms and hearing thresholds in patients with M énière’s disease, facilitating the tailored treatment.Key Points• Relationships between 3-dimensional real inversion recovery features and clinical symptoms in Mén...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Radiomics using non-contrast CT to predict hemorrhagic transformation risk in stroke patients undergoing revascularization
ConclusionsThe radiomics model can predict hemorrhagic transformation using NCCT in stroke patients. Low Hounsfield unit was a strong predictor of hemorrhagic transformation, while textural features alone can predict hemorrhagic transformation.Clinical relevance statementUsing radiomic features extracted from initial non-contrast computed tomography, early prediction of hemorrhagic transformation has the potential to improve patient care and outcomes by aiding in personalized treatment decision-making and early identification of at-risk patients.Key Points• Predicting hemorrhagic transformation following thrombolysis in ...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Quality assessment of the MRI-radiomics studies for MGMT promoter methylation prediction in glioma: a systematic review and meta-analysis
ConclusionsStudy RQS and adherence to TRIPOD guidelines was generally low. Radiomic prediction of MGMT methylation status showed great heterogeneity of results and lower performances in grade IV gliomas, which hinders its current implementation in clinical practice.Clinical relevance statementMGMT promoter methylation status appears to be variably correlated with MRI radiomic features; radiomic models are not sufficiently robust to be integrated into clinical practice to accurately predict MGMT promoter methylation status in patients with glioma before surgery.Key Points•Adherence to the indications of TRIPOD guidelines ...
Source: European Radiology - February 3, 2024 Category: Radiology Source Type: research
Breast elastography: how does it works, and for what purposes?
(Source: European Radiology)
Source: European Radiology - February 1, 2024 Category: Radiology Source Type: research
Correction: Diffusion-weighted imaging complements T2-weighted MRI for tumour response assessment in squamous anal carcinoma
(Source: European Radiology)
Source: European Radiology - February 1, 2024 Category: Radiology Source Type: research
Development and multicenter validation of deep convolutional neural network –based detection of colorectal cancer on abdominal CT
ConclusionsCUNET can detect CRC on abdominal CT in patients with various clinical situations and from external institutions.Key Points•Customized 3D U-Net of nnU-Net (CUNET) can be applied to the opportunistic detection of colorectal cancer (CRC) in abdominal CT, helping radiologists detect unexpected CRC.•CUNET showed the best performance at false-positive rates ≥ 3.0, and 30.1% of false-positives were in the colorectum. CUNET detected 69.2% (9/13) of CRCs missed by radiologists and 87.3% (48/55) of asymptomatic CRCs.•CUNET detected CRCs in multiple validation sets composed of varying clinical situations and f...
Source: European Radiology - February 1, 2024 Category: Radiology Source Type: research
Author Correction: Liver stiffness by two-dimensional shear wave elastography for screening high-risk varices in patients with compensated advanced chronic liver disease
(Source: European Radiology)
Source: European Radiology - February 1, 2024 Category: Radiology Source Type: research
