Skull and Scalp En-Bloc Harvest Protects Calvarial Perfusion: A Cadaveric Study
Conclusion Calvarial transplantation may be a technically viable option for skull defect reconstruction that requires vascularized composite tissues (bone and soft tissue) for optimal outcomes. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Journal of Reconstructive Microsurgery)
Source: Journal of Reconstructive Microsurgery - July 10, 2023 Category: Surgery Authors: Lopez, Christopher D. Girard, Alisa O. Lake, Isabel V. Suresh, Visakha Abdou, Hossam Morrison, Jonathan J. Yang, Robin Gordon, Chad R. Redett, Richard J. Tags: Original Article Source Type: research
Improved correction formulas to estimate iohexol clearance from simple models
(Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - July 8, 2023 Category: Drugs & Pharmacology Source Type: research
Application of GFR estimating equations to children with normal, near-normal, or discordant GFR
ConclusionThe formulas that most closely approximated the measured GFR varied depending on the pattern of discordant eGFR results. Based on the results, we recommend using the CKiD U25-combined formula to screen for children with a low GFR. Either the CKiD U25-combined or FAS-combined would be recommended for changes in eGFR longitudinally. However, because all formulas were discordant from the iGFR-4pt in over a third of participants, further refinement of pediatric eGFR formulas is needed at the normal/near-normal range.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary i...
Source: Pediatric Nephrology - July 7, 2023 Category: Urology & Nephrology Source Type: research
Skull and Scalp En-Bloc Harvest Protects Calvarial Perfusion: A Cadaveric Study
Conclusion Calvarial transplantation may be a technically viable option for skull defect reconstruction that requires vascularized composite tissues (bone and soft tissue) for optimal outcomes. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Journal of Reconstructive Microsurgery)
Source: Journal of Reconstructive Microsurgery - July 5, 2023 Category: Surgery Authors: Lopez, Christopher D. Girard, Alisa O. Lake, Isabel V. Suresh, Visakha Abdou, Hossam Morrison, Jonathan J. Yang, Robin Gordon, Chad R. Redett, Richard J. Tags: Original Article Source Type: research
IJERPH, Vol. 20, Pages 6238: Posterior Urethral Valves, Unilateral Vesicoureteral Reflux, and Renal Dysplasia (VURD) Syndrome: Long-Term Longitudinal Evaluation of the Kidney Function
In conclusion, VURD syndrome does not show a protective role in kidney function preservation. On the contrary, it seems to be associated with a deterioration of the kidney function on a long-term follow-up. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - June 27, 2023 Category: Environmental Health Authors: Paraboschi Giannettoni Mantica Polymeropoulos Mishra Clothier Garriboli Tags: Brief Report Source Type: research
Comparison of Cystatin C and Creatinine in the Assessment of Measured Kidney Function during Critical Illness
CONCLUSIONS: eGFR creatinine systematically over-estimated kidney function after prolonged critical illness. Cystatin C better estimated true kidney function as it appeared unaffected by the muscle loss of prolonged critical illness.PMID:37256861 | DOI:10.2215/CJN.0000000000000203 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - May 31, 2023 Category: Urology & Nephrology Authors: Ryan W Haines Alex J Fowler Kaifeng Liang Rupert M Pearse Anders O Larsson Zudin Puthucheary John R Prowle Source Type: research
Comparison of Cystatin C and Creatinine in the Assessment of Measured Kidney Function during Critical Illness
CONCLUSIONS: eGFR creatinine systematically over-estimated kidney function after prolonged critical illness. Cystatin C better estimated true kidney function as it appeared unaffected by the muscle loss of prolonged critical illness.PMID:37256861 | DOI:10.2215/CJN.0000000000000203 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - May 31, 2023 Category: Urology & Nephrology Authors: Ryan W Haines Alex J Fowler Kaifeng Liang Rupert M Pearse Anders O Larsson Zudin Puthucheary John R Prowle Source Type: research
Facilitated encapsulation of a nonionic contrast agent for X-ray computed tomography into lipid vesicles by the multiple emulsification-solvent evaporation method
Colloids Surf B Biointerfaces. 2023 May 18;227:113360. doi: 10.1016/j.colsurfb.2023.113360. Online ahead of print.ABSTRACTWe studied the encapsulation of iohexol (Ihex), a nonionic contrast agent used for X-ray computational tomography, into lipid vesicles using the multiple emulsification-solvent evaporation method to formulate a nanosized contrast agent. This lipid vesicle preparation method consists of three steps: (1) primary emulsification for producing water-in-oil (W/O) emulsions containing fine water droplets that will be converted to the internal water phase of the lipid vesicles, (2) secondary emulsification for ...
Source: Colloids and Surfaces - May 25, 2023 Category: Biotechnology Authors: Yumeto Ogata Takashi Kuroiwa Sosaku Ichikawa Source Type: research
Facilitated encapsulation of a nonionic contrast agent for X-ray computed tomography into lipid vesicles by the multiple emulsification-solvent evaporation method
Colloids Surf B Biointerfaces. 2023 May 18;227:113360. doi: 10.1016/j.colsurfb.2023.113360. Online ahead of print.ABSTRACTWe studied the encapsulation of iohexol (Ihex), a nonionic contrast agent used for X-ray computational tomography, into lipid vesicles using the multiple emulsification-solvent evaporation method to formulate a nanosized contrast agent. This lipid vesicle preparation method consists of three steps: (1) primary emulsification for producing water-in-oil (W/O) emulsions containing fine water droplets that will be converted to the internal water phase of the lipid vesicles, (2) secondary emulsification for ...
Source: Colloids and Surfaces - May 25, 2023 Category: Biotechnology Authors: Yumeto Ogata Takashi Kuroiwa Sosaku Ichikawa Source Type: research
Disinfection byproducts of iopamidol, iohexol, diatrizoate and their distinct acute toxicity on Scenedesmus sp., Daphnia magna and Danio rerio
In this study, the degradation of three typical ICM (iopamidol, iohexol, diatrizoate) at initial concentration of 10 μM and 100 μM in chlorination and peracetic acid without or with NH4+ was investigated, and the potential acute toxicity of treated disinfected water containing potential ICM-derived DBPs on Daphnia magna, Scenedesmus sp. and Danio rerio was tested. The degradation results suggested that only iopamidol was significantly degraded (level of degradation >98%) by chlorination, and the degradation rate of iohexol and diatrizoate were significantly increased in chlorination with NH4+. All three ICM were not d...
Source: Chemosphere - May 20, 2023 Category: Chemistry Authors: Nan Zhou Huihui Liu Xianhai Yang Peter Watson Feifei Yang Source Type: research
Disinfection byproducts of iopamidol, iohexol, diatrizoate and their distinct acute toxicity on Scenedesmus sp., Daphnia magna and Danio rerio
In this study, the degradation of three typical ICM (iopamidol, iohexol, diatrizoate) at initial concentration of 10 μM and 100 μM in chlorination and peracetic acid without or with NH4+ was investigated, and the potential acute toxicity of treated disinfected water containing potential ICM-derived DBPs on Daphnia magna, Scenedesmus sp. and Danio rerio was tested. The degradation results suggested that only iopamidol was significantly degraded (level of degradation >98%) by chlorination, and the degradation rate of iohexol and diatrizoate were significantly increased in chlorination with NH4+. All three ICM were not d...
Source: Chemosphere - May 20, 2023 Category: Chemistry Authors: Nan Zhou Huihui Liu Xianhai Yang Peter Watson Feifei Yang Source Type: research
Disinfection byproducts of iopamidol, iohexol, diatrizoate and their distinct acute toxicity on Scenedesmus sp., Daphnia magna and Danio rerio
In this study, the degradation of three typical ICM (iopamidol, iohexol, diatrizoate) at initial concentration of 10 μM and 100 μM in chlorination and peracetic acid without or with NH4+ was investigated, and the potential acute toxicity of treated disinfected water containing potential ICM-derived DBPs on Daphnia magna, Scenedesmus sp. and Danio rerio was tested. The degradation results suggested that only iopamidol was significantly degraded (level of degradation >98%) by chlorination, and the degradation rate of iohexol and diatrizoate were significantly increased in chlorination with NH4+. All three ICM were not d...
Source: Chemosphere - May 20, 2023 Category: Chemistry Authors: Nan Zhou Huihui Liu Xianhai Yang Peter Watson Feifei Yang Source Type: research
Disinfection byproducts of iopamidol, iohexol, diatrizoate and their distinct acute toxicity on Scenedesmus sp., Daphnia magna and Danio rerio
In this study, the degradation of three typical ICM (iopamidol, iohexol, diatrizoate) at initial concentration of 10 μM and 100 μM in chlorination and peracetic acid without or with NH4+ was investigated, and the potential acute toxicity of treated disinfected water containing potential ICM-derived DBPs on Daphnia magna, Scenedesmus sp. and Danio rerio was tested. The degradation results suggested that only iopamidol was significantly degraded (level of degradation >98%) by chlorination, and the degradation rate of iohexol and diatrizoate were significantly increased in chlorination with NH4+. All three ICM were not d...
Source: Chemosphere - May 20, 2023 Category: Chemistry Authors: Nan Zhou Huihui Liu Xianhai Yang Peter Watson Feifei Yang Source Type: research
27 Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment
Conclusion
Our findings raise clinicians’ awareness about ARC potentially being present in children after major surgery. This knowledge allows to anticipate on enhanced elimination of drugs by using empirically adjusted dosing regimens immediately from the start of treatment. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - May 18, 2023 Category: Pediatrics Authors: Dhont, E., Heggen, T. V. D., Snauwaert, E., Willems, J., Walle, J. V., de Cock, P. Tags: General abstracts Source Type: research
