Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research

Expression of GRP78 and its copartners in HEK293 and pancreatic cancer cell lines (BxPC-3/PANC-1) exposed to MRI and CT contrast agents
Nucleosides Nucleotides Nucleic Acids. 2023 Oct 3:1-26. doi: 10.1080/15257770.2023.2263496. Online ahead of print.ABSTRACTEndoplasmic reticulum (ER) stress-associated chaperones trigger a defense mechanism called as unfolded protein response (UPR) which can manage apoptosis and be determinative in cell fate. Both anticancer drug effects and potential toxicity effects of magnetic resonance imaging (MRI) and computed tomography (CT) contrast agents were aimed to be evaluated. For this purpose, we investigated expression profiles of endoplasmic reticulum stress-associated chaperone molecules in human pancreatic tumor lines Bx...
Source: Nucleosides, Nucleotides and Nucleic Acids - October 3, 2023 Category: Biochemistry Authors: Ali Ahmed Azzawri Ibrahim Halil Yildirim Zeynep Yegin Abdurrahim Dusak Source Type: research

Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research

Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research

Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research

Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research

Characterization of single- and multi-energy CT performance of an oral dark borosilicate contrast media using a clinical photon-counting-detector CT platform
CONCLUSIONS: When evaluated at different tube potentials and VMI energy levels using a clinical PCD-CT system, DBCM showed consistently higher CNR compared to iodine versus water (a neutral contrast).PMID:37669507 | DOI:10.1002/mp.16713 (Source: Health Physics)
Source: Health Physics - September 5, 2023 Category: Physics Authors: Liqiang Ren Yuxin Sun Benjamin Yeh Jeffrey F Marsh Timothy N Winfree Kristin A Burke Kishore Rajendran Cynthia H McCollough Achille Mileto Joel G Fletcher Shuai Leng Source Type: research

Contrast conservation measures during the global iohexol contrast shortage crisis did not affect stroke thrombectomy outcomes
Conclusions Modifying stroke workflow to adapt to the current global shortage in iohexol is feasible. Using diluted iohexol (50% contrast mixed with 50% heparinized saline) did not affect MT outcomes. (Source: Journal of NeuroInterventional Surgery)
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Almallouhi, E., Sattur, M., Lajthia, O., Kicielinski, K. P., Holmstedt, C., Lena, J. R., Al Kasab, S., Spiotta, A. M. Tags: Ischemic stroke Source Type: research