Rosiglitazone Alleviates Contrast-Induced Acute Kidney Injury in Rats via the PPAR < em > γ < /em > /NLRP3 Signaling Pathway
CONCLUSION: Rosiglitazone could alleviate acute renal injury in the CI-AKI rat model by regulating the PPARγ/NLRP3 signaling pathway and should be further investigated as a potential treatment in clinical studies.PMID:36225198 | PMC:PMC9550500 | DOI:10.1155/2022/4158692 (Source: Disease Markers)
Source: Disease Markers - October 13, 2022 Category: Laboratory Medicine Authors: Jiayi Wu Jinhua Huang En Chen Xingchun Zheng Source Type: research
Efficient oral delivery of water-soluble CT contrast agent using an W < sub > 1 < /sub > /O/W < sub > 2 < /sub > alginate hydrogel matrix
Colloids Surf B Biointerfaces. 2022 Sep 20;220:112862. doi: 10.1016/j.colsurfb.2022.112862. Online ahead of print.ABSTRACTHYPOTHESIS: Iohexol (IOH) is a commonly used second-generation nonionic iodinated contrast agent. However, low gastrointestinal mucosal adherence and high downstream speed limit its application in intestinal Computed tomography (CT) imaging. We hypothesize that oral IOH delivery carriers composed of environmentally responsive materials enable the intestinal targeted delivery and prolong the intestinal residence time of IOH, enhancing the intestinal disease detection efficiency.EXPERIMENTS: An emulsion-f...
Source: Colloids and Surfaces - October 6, 2022 Category: Biotechnology Authors: Meng Ren Na Li Xuliang Jiang Xianhe Liu Aihua Zou Source Type: research
Efficient oral delivery of water-soluble CT contrast agent using an W < sub > 1 < /sub > /O/W < sub > 2 < /sub > alginate hydrogel matrix
Colloids Surf B Biointerfaces. 2022 Sep 20;220:112862. doi: 10.1016/j.colsurfb.2022.112862. Online ahead of print.ABSTRACTHYPOTHESIS: Iohexol (IOH) is a commonly used second-generation nonionic iodinated contrast agent. However, low gastrointestinal mucosal adherence and high downstream speed limit its application in intestinal Computed tomography (CT) imaging. We hypothesize that oral IOH delivery carriers composed of environmentally responsive materials enable the intestinal targeted delivery and prolong the intestinal residence time of IOH, enhancing the intestinal disease detection efficiency.EXPERIMENTS: An emulsion-f...
Source: Colloids and Surfaces - October 6, 2022 Category: Biotechnology Authors: Meng Ren Na Li Xuliang Jiang Xianhe Liu Aihua Zou Source Type: research
Efficient oral delivery of water-soluble CT contrast agent using an W < sub > 1 < /sub > /O/W < sub > 2 < /sub > alginate hydrogel matrix
Colloids Surf B Biointerfaces. 2022 Sep 20;220:112862. doi: 10.1016/j.colsurfb.2022.112862. Online ahead of print.ABSTRACTHYPOTHESIS: Iohexol (IOH) is a commonly used second-generation nonionic iodinated contrast agent. However, low gastrointestinal mucosal adherence and high downstream speed limit its application in intestinal Computed tomography (CT) imaging. We hypothesize that oral IOH delivery carriers composed of environmentally responsive materials enable the intestinal targeted delivery and prolong the intestinal residence time of IOH, enhancing the intestinal disease detection efficiency.EXPERIMENTS: An emulsion-f...
Source: Colloids and Surfaces - October 6, 2022 Category: Biotechnology Authors: Meng Ren Na Li Xuliang Jiang Xianhe Liu Aihua Zou Source Type: research
Gadolinium Enhances Dual-energy Computed Tomography Scan of Pulmonary Artery
ConclusionGd-CTPA is recommended to patients who are unsuitable for receiving an iodine-based CTPA. Furthermore, a turbo flash scan could surpass a dual-energy scan without consideration for virtual monoenergetic imaging. (Source: Journal of Huazhong University of Science and Technology -- Medical Sciences --)
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - September 30, 2022 Category: Research Source Type: research
Iohexol plasma and urinary concentrations in cirrhotic patients: A pilot study
CONCLUSION: Plasma clearance of iohexol seems useful for determining GFR regardless of the ascites grade. We will secondly devise a pharmacokinetics model requiring fewer samples andvalidate the BM equation.PMID:36157874 | PMC:PMC9453460 | DOI:10.4254/wjh.v14.i8.1621 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - September 26, 2022 Category: Gastroenterology Authors: Paul Carrier Alexandre Destere Baptiste Giguet Marilyne Debette-Gratien Marie Essig Caroline Monchaud Jean-Baptiste Woillard V éronique Loustaud-Ratti Source Type: research
