Letter to the Editor: Myocarditis Associated With SARS-CoV-2 Vaccination Diagnosed by Cardiac MRI Requires Confirmation by Endomyocardial Biopsy
J Korean Med Sci. 2024 Apr 1;39(12):e124. doi: 10.3346/jkms.2024.39.e124.NO ABSTRACTPMID:38565180 | PMC:PMC10985500 | DOI:10.3346/jkms.2024.39.e124 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 2, 2024 Category: General Medicine Authors: Josef Finsterer Sounira Mehri Source Type: research

Letter to the Editor: Myocarditis Associated With SARS-CoV-2 Vaccination Diagnosed by Cardiac MRI Requires Confirmation by Endomyocardial Biopsy
J Korean Med Sci. 2024 Apr 1;39(12):e124. doi: 10.3346/jkms.2024.39.e124.NO ABSTRACTPMID:38565180 | PMC:PMC10985500 | DOI:10.3346/jkms.2024.39.e124 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 2, 2024 Category: Biomedical Science Authors: Josef Finsterer Sounira Mehri Source Type: research

Letter to the Editor: Myocarditis Associated With SARS-CoV-2 Vaccination Diagnosed by Cardiac MRI Requires Confirmation by Endomyocardial Biopsy
J Korean Med Sci. 2024 Apr 1;39(12):e124. doi: 10.3346/jkms.2024.39.e124.NO ABSTRACTPMID:38565180 | PMC:PMC10985500 | DOI:10.3346/jkms.2024.39.e124 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 2, 2024 Category: General Medicine Authors: Josef Finsterer Sounira Mehri Source Type: research

Letter to the Editor: Myocarditis Associated With SARS-CoV-2 Vaccination Diagnosed by Cardiac MRI Requires Confirmation by Endomyocardial Biopsy
J Korean Med Sci. 2024 Apr 1;39(12):e124. doi: 10.3346/jkms.2024.39.e124.NO ABSTRACTPMID:38565180 | PMC:PMC10985500 | DOI:10.3346/jkms.2024.39.e124 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 2, 2024 Category: Biomedical Science Authors: Josef Finsterer Sounira Mehri Source Type: research

Role of Treg cell subsets in cardiovascular disease pathogenesis and potential therapeutic targets
Front Immunol. 2024 Mar 15;15:1331609. doi: 10.3389/fimmu.2024.1331609. eCollection 2024.ABSTRACTIn the genesis and progression of cardiovascular diseases involving both innate and adaptive immune responses, inflammation plays a pivotal and dual role. Studies in experimental animals indicate that certain immune responses are protective, while others exacerbate the disease. T-helper (Th) 1 cell immune responses are recognized as key drivers of inflammatory progression in cardiovascular diseases. Consequently, the CD4+CD25+FOXP3+ regulatory T cells (Tregs) are gaining increasing attention for their roles in inflammation and ...
Source: Atherosclerosis - April 1, 2024 Category: Cardiology Authors: Yuanliang Xia Di Gao Xu Wang Bin Liu Xue Shan Yunpeng Sun Dashi Ma Source Type: research

Eosinophilic Myocarditis After Heart Transplantation
We present a case of a patient with eosinophilic myocarditis after heart transplantation progressing to cardiogenic shock. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , G. Campos, S. Moraes, S. Mangini, X. Jos é Leudo, A. Barbara, F. Bacal Source Type: research

Fulminant Lymphocytic Myocarditis with Acute Biventricular Failure: The Role of Mechanical Circulatory Support
Introduction: Fulminant lymphocytic myocarditis (FLM) frequently leads to severe outcomes, such as cardiogenic shock (CS), ventricular tachyarrhythmias, or bradyarrhythmias, which can have an acute and fatal course. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Aijaz, S. Shoukat, R. Sharma, S. Farooq, H. Ashraf, B. Akkanti, I. Hussain, , S. Nathan, M. Patel, I. Gregoric, B. Kar Source Type: research

The Great Masquerader: Lymphocytic Myocarditis Masking as Cardiac Sarcoidosis: A Case of Severe Non-Ischemic Cardiomyopathy and Ventricular Tachycardia Storm
Introduction: Among the several etiologies leading to non-ischemic cardiomyopathies, lymphocytic myocarditis and cardiac sarcoidosis may be particularly difficult to distinguish due to similarities in clinical presentation and associated findings in advanced imaging modalities. Here, we discuss a case of severe non-ischemic cardiomyopathy caused by lymphocytic myocarditis initially diagnosed and managed as cardiac sarcoidosis. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Doddi, J. Avalon, M. Awad, J.D. Mills, M. Caccamo Source Type: research

One of a Kind: A Rare Case of Cardiac Transplantation in a Patient with Eosinophilic Endomyocardial Fibrosis
Introduction: Eosinophilic myocarditis is an inflammatory cardiomyopathy characterized by eosinophilic infiltration of the myocardium leading to fibrosis. It can be seen in malignancy and immune-mediated disorders. Patients can present acutely with myocarditis or chronically as restrictive cardiomyopathy (RC), known as Loeffler ’s endocarditis (eosinophilic endomyocardial fibrosis). The symptoms may be non-specific, and a definitive diagnosis is made with cardiac Magnetic Resonance Imaging (cMRI) or endomyocardial biopsy. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Girgis, J. Celenza-Salvatore, C. Gidea, F. Ali, M. Montgomery, N. Hochbaum, B. Fyfe-Kirschner, S. Kapoor Source Type: research

The Role of Multimodal Imaging in Guiding Myocardial Recovery: A Case of LVAD Explantation Following Concurrent Lymphocytic and COVID-19 Myocarditis
Introduction: This case study showcases the role of multimodal imaging in demystifying complex cardiac conditions and guiding myocardial recovery processes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Bindra Source Type: research

Outcomes of Heart Transplant Recipients with Giant Cells or Eosinophils on Endomyocardial Biopsy
Purpose: Allograph rejection after orthotopic heart transplant (OHT) remains a major cause of morbidity and mortality. Giant cell or eosinophilic myocarditis after OHT is associated with acute rejection and poor outcomes. The significance of giant cells (GC) or eosinophils (EOS) on endomyocardial biopsy (EMB) in the absence of higher-grade rejection remains uncertain. We analyzed the outcomes from our center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Woodham, M. McLenon, M. Philbrick, A. Topik, A. Kumar, M.A. Urey, K. Hong, J. Silva Enciso Source Type: research

Clinical Features to Predict Weaning from Ventricular Assist Device in Pediatric Patients with Myocarditis
Purpose: Myocarditis in pediatric patients can lead to severe heart failure, necessitating ventricular assist devices (VAD) which might serve as a bridge to transplant or as a temporary circulatory support until myocardial recovery. We aimed to identify differences in the clinical and diagnostic findings at initial admission between pediatric patients who could be successfully weaned from VAD and those who could not. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , T. Hecht, M. Boehne, B. Opgen-Rhein, F. Anderheiden, B. Wannenmacher, M. Fischer, B. Ruf, K. Reineker, M. Grafmann, G. Wiegand, P. Murin, E. Schwarzkopf, T. Pickardt, O. Miera, D. Messroghli, S. Schubert, F. Seidel Source Type: research

212 Incidence and Outcomes of MRI-confirmed Myocarditis in Patients Receiving Immune Checkpoint Inhibitors for Lung Cancer - A Single Tertiary Centre Experience
Myocarditis is a rare and life-threatening complication of immune checkpoint inhibitors (ICI). Lung cancer patients present a diagnostic conundrum with overlapping symptoms, co-morbidities, treatment toxicity, and tumour burden. (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Alfred So, Arjun K Ghosh, Charlotte Manisty, Adam Januszweski Tags: Case Reports Source Type: research

Myocardial Injury by COVID-19 Infection Assessed by Cardiovascular Magnetic Resonance Imaging  - A Prospective Multicenter Study
CONCLUSIONS: This study revealed a high incidence of myocardial injury identified by CMR in patients with moderate to severe COVID-19 and abnormal findings for cardiac biomarkers.PMID:38556299 | DOI:10.1253/circj.CJ-23-0729 (Source: Circulation Journal)
Source: Circulation Journal - March 31, 2024 Category: Cardiology Authors: Shingo Kato Takeshi Kitai Daisuke Utsunomiya Mai Azuma Kazuki Fukui Eri Hagiwara Takashi Ogura Yuki Ishibashi Taiji Okada Hiroki Kitakata Yasuyuki Shiraishi Shunsuke Torii Koichi Ohashi Kazufumi Takamatsu Akihito Yokoyama Ken-Ichi Hirata Yuya Matsue Koich Source Type: research

Role of CCRL2 in the Pathogenesis of Experimental Autoimmune Myocarditis via P21-Activated Kinase 1/NOD-Like Receptor Protein 3 Pathway
This study aims to elucidate the effect of Chemokine (C C motif) receptor-like 2 (CCRL2) in experimental autoimmune myocarditis (EAM) occurrence and its potential regulatory mechanisms.EAM was simulated in a mouse model injected with α-myosin-heavy chain. The changes on EAM were assessed through histological staining of heart tissues, including measuring cardiac troponin I (cTnI), proinflammatory cytokines, transferase-mediated dUTP nick end labeling (TUNEL) assay, and cardiac function. Then, the heart tissues from the EAM mouse model and control groups were analyzed through transcriptome sequencing to identify the differ...
Source: International Heart Journal - March 31, 2024 Category: Cardiology Authors: Lin Chen Jing Meng Jia Zheng Tingting Zhao Qi Li Chengzhi Lu Source Type: research