Markers of Endothelial Dysfunction in Kawasaki Disease: An Update
AbstractKawasaki disease (KD) is a medium vessel vasculitis that has a special predilection for coronary arteries. Cardiovascular complications include the development of coronary artery abnormalities (CAAs) and myocarditis. Endothelial dysfunction (ED) is now recognized to be a key component in the pathogenesis of KD and is believed to contribute to the development of CAAs. ED has been evaluated by several clinical parameters. However, there is paucity of literature on laboratory markers for ED in KD. The evaluation of ED can be aided by the identification of biomarkers such as oxidative stress markers, circulating cells ...
Source: Clinical Reviews in Allergy and Immunology - March 11, 2024 Category: Allergy & Immunology Source Type: research
Yohimbine Treatment Alleviates Cardiac Inflammation/Injury and Improves Cardiac Hemodynamics by Modulating Pro-Inflammatory and Oxidative Stress Indicators
This study emphasizes yohimbine's therapeutic benefit against LPS-induced myocarditis and associated inflammatory markers response by regulating the MAPK pathway. (Source: Inflammation)
Source: Inflammation - March 11, 2024 Category: Allergy & Immunology Source Type: research
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner
Clinical and experimental studies have shown that the myocardial inflammatory response during pathological events varies between males and females. However, the cellular and molecular mechanisms of these sex d... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - March 7, 2024 Category: Molecular Biology Authors: Marie Louise Ndzie Noah, Richard Mprah, Prosperl Ivette Wowui, Adebayo Oluwafemi Adekunle, Joseph Adu-Amankwaah, Rubin Tan, Zheng Gong, Tao Li, Lu Fu, Jeremiah Ong ’achwa Machuki, Shijie Zhang and Hong Sun Tags: Research Source Type: research
