Systemic Inflammatory Stress Response During Cardiac Surgery.
Authors: Sugita J, Fujiu K PMID: 29848891 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Sinus Node Recovery Time Can Predict Maintenance of Sinus Rhythm After Catheter Ablation for Long-Standing Atrial Fibrillation.
Authors: Imai Y, Yokoyama Y, Watanabe T PMID: 29848892 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Cardiomyopathy with LMNA Mutation.
Authors: Ito M, Nomura S PMID: 29848893 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Targeting Vascular Inflammaging with Amlodipine for Atherosclerosis Prevention.
Authors: Harada M, Ishizuka M, Murakami H, Toko H PMID: 29848894 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Letter by Xiao and Song Regarding the Article "Relation Between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function".
Letter by Xiao and Song Regarding the Article "Relation Between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function". Int Heart J. 2018;59(3):668 Authors: Xiao CY, Song ZZ PMID: 29848895 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Reply to Letter by Xiao and Song Regarding the Article, "Relation between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function".
Reply to Letter by Xiao and Song Regarding the Article, "Relation between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function". Int Heart J. 2018;59(3):669 Authors: Baessler A, Zeller J PMID: 29848896 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Errata: Can Anti-inflammatory Therapy Prevent Atrial Fibrillation in Myocardial Infarction Patients?
Authors: Nakayama Y, Fujiu K Abstract An error appeared in the article titled "Can Anti-inflammatory Therapy Prevent Atrial Fibrillation in Myocardial Infarction Patients?" by Yukiteru Nakayama and Katsuhito Fujiu (Vol. 59, No. 1, 3-5, 2018).The name of the last author on page 3 should be "Katsuhito Fujiu" and not "Katushito Fujiu". PMID: 29848897 [PubMed - in process] (Source: International Heart Journal)
Source: International Heart Journal - June 1, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Clinical Characteristics and Mid-Term Outcomes of Non-Elderly Obese Patients with Acute Decompensated Heart Failure in Japan.
Authors: Ito M, Wada H, Sakakura K, Ibe T, Ugata Y, Fujita H, Momomura SI Abstract Obesity is a well-known risk factor for cardiovascular diseases including heart failure (HF). However, some literatures suggested better clinical outcomes in obese patients with HF. Since higher body mass index (BMI) levels of HF patients were significantly associated with younger age, the impact of obesity on clinical outcomes in non-elderly HF patients should be elucidated.Consecutive 155 non-elderly acute decompensated HF patients (
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Effect of Geranylgeranyl Pyrophosphate Synthase on Hypoxia/Reoxygenation-Induced Injury in Heart-Derived H9c2 Cells.
The objective of this work was to investigate the effect of GGPPS on MIR injury in H9c2 cells subjected to hypoxia/reoxygenation (HR) to mimic MIR. Prior to HR, the cells were transfected with GGPPS, shGGPPS, or shGFP. The results showed that cell viability was reduced, and cell injury and cell apoptosis were increased as a result of overexpression of GGPPS. Knockdown of GGPPS improved cell viability, and decreased cell injury and cell apoptosis. Furthermore, overexpression of GGPPS increased Rac1 activity and ROS generation, while GGPPS silencing decreased Rac1 activity and ROS generation. Based on these findings, we prop...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Combined Evaluation of the Plasma Arginine Vasopressin and Noradrenaline Levels May be a Useful Predictor of the Prognosis of Patients with Acute Decompensated Heart Failure.
Authors: Atsumi W, Tani S, Tachibana E, Hirayama A Abstract Few data exist regarding the association of plasma arginine vasopressin (AVP) and noradrenaline (NA) levels with subsequent cardiac events in acute decompensated heart failure (ADHF) patients. We measured plasma AVP and NA levels in ADHF patients on admission. In the follow-up (median: 487 days) of 291 patients, 41 cardiac events (cardiac death or re-hospitalization due to HF) were documented. The plasma AVP (26.4 versus 15.5 pg/mL, P = 0.014) and plasma NA (2347 versus 1524 pg/mL, P = 0.007) levels in the cardiac events group were significantly higher tha...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Successful Treatment of Protein-Losing Enteropathy and Plastic Bronchitis by Biphasic Cuirass Ventilation in a Patient with Failing Fontan Circulation.
We present a 16-year-old male patient with hypoplastic left heart syndrome who developed protein-losing enteropathy (PLE) and plastic bronchitis (PB) after a Fontan operation. He received medical therapies, including albumin infusion, unfractionated heparin, and high-dose anti-aldosterone therapy but could not obtain clinical relief. Biphasic cuirass ventilation (BCV) led to expectoration of bronchial casts and prompt resolution of PB. Notably, clinical symptoms related to PLE were dramatically improved after starting BCV. A brief period of BCV increased stroke volume from 26±1.4 to 39±4.0 mL. This case sugge...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Catecholamine-Induced Senescence of Endothelial Cells and Bone Marrow Cells Promotes Cardiac Dysfunction in Mice.
Authors: Katsuumi G, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Wakasugi T, Nakao M, Minamino T Abstract Previous studies have suggested that cellular senescence plays a central role in the progression of pathologic changes in the failing heart. It is well known that the sympathetic nervous system is activated in patients with heart failure, and this change is associated with poor clinical outcomes. Sympathetic activation increases the levels of various catecholamines, such as epinephrine and norepinephrine, but the contribution of these catecholamines to cellular senescence associated with heart failure r...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Cardiomyopathy Phenotypes and Pregnancy Outcomes with Left Ventricular Noncompaction Cardiomyopathy.
We report the cases of three pregnant Japanese women definitively diagnosed with LVNC prepregnancy. Case 1 presented LVNC with restrictive phenotype. Her pregnancy was terminated due to exacerbated pulmonary hypertension and low output status at 30 weeks' gestation. Case 2 presented isolated LVNC with nonsustained ventricle tachycardia. A cesarean section was performed at 36 weeks' gestation because of placenta previa. Case 3 presented dilated LVNC. Labor induction was performed because of decreased left ventricular ejection fraction, leading to a vaginal delivery at 37 weeks' gestation. In all cases, no thromboembolic eve...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Importance of Carefulness in Accurate Diagnosis.
We describe a case status post collision with an iron ball and discuss how to detect myocardial infarction. We emphasize the importance of careful interview, physical examination, and electrocardiogram even in seemingly healthy patients. A severe blow, such as that described, can impair coronary artery flow and may potentially cause myocardial infarction. PMID: 29794383 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Coronary Artery Perforation During Percutaneous Coronary Intervention in a Patient with a Prior Modified Bentall Procedure.
We report on a 73-year-old woman who presented with heart failure secondary to graft stenosis of the right coronary artery 6 months after undergoing a modified Bentall procedure. Percutaneous coronary intervention (PCI) was performed and type II coronary artery perforation occurred during PCI of the right coronary artery. We used a perfusion balloon and achieved hemostasis successfully. We report a case of coronary artery perforation that was treated with perfusion balloon during PCI in a patient with a prior modified Bentall procedure. In addition, we present a case series of PCI for ostial coronary stenosis after the Ben...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

A Case of Pulmonary Hypertension Associated with Idiopathic Hypereosinophilic Syndrome.
We present a case of a 39-year-old man who was diagnosed with pulmonary hypertension (PH) associated with idiopathic HES. Although the pulmonary arterial hypertension specific drugs including intravenous epoprostenol could not control his PH, corticosteroid was effective for both hypereosinophilia and PH. Our case suggests the importance of steroid therapy as well as specific drugs for pulmonary arterial hypertension in the treatment of PH associated with HES. PMID: 29794385 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

What is the Optimal Strategy for Adaptive Servo-Ventilation Therapy?
Authors: Imamura T, Kinugawa K Abstract Clinical advantages in the adaptive servo-ventilation (ASV) therapy have been reported in selected heart failure patients with/without sleep-disorder breathing, whereas multicenter randomized control trials could not demonstrate such advantages. Considering this discrepancy, optimal patient selection and device setting may be a key for the successful ASV therapy. Hemodynamic and echocardiographic parameters indicating pulmonary congestion such as elevated pulmonary capillary wedge pressure were reported as predictors of good response to ASV therapy. Recently, parameters indic...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Occurrence of Potentially Lethal Arrhythmia due to Sudden Exposure of an Overt Accessory Pathway 8 Years After Catheter Ablation of a Concealed Accessory Pathway.
Authors: Yazaki K, Enta K, Watarai M, Kahata M, Kumagai A, Inoue K, Koganei H, Otsuka M, Ishii Y Abstract Although the efficacy of catheter ablation of the accessory pathway (AP) has been established, there are subgroups of APs with an intermittent conduction property, which is sometimes difficult to diagnose accurately. A 57-year-old man with a history of catheter ablation was referred to our clinic due to frequent faintness. He had undergone concealed AP ablation 8 years previously and bilateral circumferential pulmonary vein isolation (CPVI) 6 years previously. During regular electrocardiogram monitoring, it was...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Spontaneous Coronary Artery Dissection Accompanied with Antiphospholipid Syndrome and Leukemia.
We report a rare spontaneous coronary artery dissection (SCAD) case accompanied by antiphospholipid syndrome (APS) and leukemia which was treated successfully with drug-eluted stents (DES) implantation. This young SCAD patient was initially diagnosed of acute myocardial infarction (AMI); however, except for 6 pack-years of smoking, there were no risk factors or family history of coronary artery disease. Subsequently, we screened other clinical status like autoimmune diseases and finally found APS. In general, APS was associated with thromboembolism events, not coronary artery dissection. Our case indicated that SCAD could ...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Exacerbated Peri-Stent Contrast Staining on Serial Angiography and Optical Coherence Tomography After Platinum-Chromium Everolimus-Eluting Stent Implantation for Infrapopliteal Artery Lesions.
Authors: Tomoi Y, Kuramitsu S, Soga Y, Hiramori S, Ando K Abstract Unlike coronary arteries, little is known about peri-stent contrast staining (PSS) formation after drug-eluting stent (DES) implantation for infrapopliteal arteries. Herein, we report exacerbated PSS assessed by serial angiography and optical coherence tomography (OCT) after platinum-chromium everolimus-eluting stent (PtCr-EES) implantation for infrapopliteal artery lesions. A 68-year-old women with recurrent left critical limb ischemia was admitted to our hospital. Standard endovascular techniques were performed for the popliteal artery (POP) and t...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Change of Exhaled Acetone Concentration Levels in Patients with Acute Decompensated Heart Failure.
This study included 19 patients with ADHF (ADHF group) and eight patients with stable heart failure (control group). Exhaled acetone was collected from these patients, and the concentration was measured with gas chromatography.The ADHF group had higher heart rates (P = 0.046), higher New York Heart Association class (P
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Importance of Early Diagnosis of Cardiac Sarcoidosis in Patients with Complete Atrioventricular Block.
Authors: Kaida T, Inomata T, Minami Y, Yazaki M, Fujita T, Iida Y, Ikeda Y, Nabeta T, Ishii S, Naruke T, Maekawa E, Koitabashi T, Ako J Abstract Our aim is to clarify the factors for early diagnosis of cardiac sarcoidosis (CS) in patients with complete atrioventricular block (CAVB) and its impact on cardiac function after corticosteroid therapy.A total of 15 CS patients with CAVB who underwent corticosteroid therapy were retrospectively analyzed. Patients were divided into two groups according to the time from the first CAVB onset to the diagnosis of CS. Clinical characteristics and outcomes were compared between t...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Effectiveness of Nitroglycerin in Managing Subacute Lung Bleeding Induced by Balloon Pulmonary Angioplasty.
Authors: Minatsuki S, Kiyosue A, Saito A, Maki H, Hatano M, Komuro I Abstract Lung bleeding (LB) and hemoptysis is a common but life-threating complication of balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension. LBs related to BPA mostly occur acutely during BPA session. Therefore, it can usually be managed with occlusion balloon or other catheter-based approaches. While LB also develops subacutely after BPA session, the pharmacological option to subacute LB is currently limited. Here, we present a case of subacute LB which can be managed with intravenous administration of nitrogly...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Sequential Grafting of in Situ Skeletonized Left Internal Mammary Artery to the Left Coronary System.
Authors: Ji Q, Xia L, Shi Y, Ma R, Shen J, Lai H, Ding W, Wang C Abstract Sequential grafting may be an effective way to maximize the benefits of the left internal mammary artery (LIMA) conduit. Despite increasing clinical application, the strategy of sequential LIMA grafting has not been proven its superiority. This single-center retrospective study aimed to evaluate the in-hospital and mid-term outcomes of sequential grafting of in situ skeletonized LIMA to the left coronary system.According to the use of sequential or separate LIMA grafting, 1505 eligible patients were assigned to a sequential group (n = 230) an...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Endovascular Embolization of Coronary Artery-Pulmonary Artery Fistulas with Double Coronary Aneurysms.
Authors: Tanaka K, Isihida M, Tanaka R, Itoh T, Naganuma Y, Osaki T, Yoshioka K, Morino Y Abstract A 75-year-old woman with chest discomfort and a continuous murmur was admitted to our hospital. During noninvasive examination, computed tomography angiography showed a coronary artery-pulmonary artery fistula with double giant coronary aneurysms (one was 42 mm× 32 mm× 32 mm, and the other was 25 mm× 20 mm× 17 mm) arising from the proximal part of the left anterior descending (LAD) artery. Stress myocardial scintigraphy showed ischemia at the LAD area. Given her frailty, the heart team, includi...
Source: International Heart Journal - May 30, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Impact of Sinus Node Recovery Time after Long-Standing Atrial Fibrillation Termination on the Long-Term Outcome of Catheter Ablation.
Authors: Yamaguchi N, Okumura Y, Watanabe I, Nagashima K, Takahashi K, Iso K, Watanabe R, Arai M, Mano H, Kogawa R, Kurokawa S, Ohkubo K, Nakai T, Hirayama A, Sonoda K, Tosaka T Abstract Atrial electrical and structural remodeling is related to the perpetuation of atrial fibrillation (AF) subsequent to sinus node dysfunction. We investigated the relationship between AF recurrence after catheter ablation and sinus node dysfunction in long-standing persistent AF patients using the sinus node recovery time (SNRT) after defibrillation.Fifty-one consecutive patients who underwent a first ablation for long-standing persi...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Safety of Reversing Anticoagulation by Protamine Following Elective Transfemoral Percutaneous Coronary Intervention in the Drug-Eluting Stent Era.
In conclusion, the use of protamine for manual compression following elective transfemoral PCI was safe and was associated with less bleeding complications. PMID: 29743410 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Effects of Verapamil and Pinacidil on Extracellular K+, pH, and the Incidence of Ventricular Fibrillation during 60 Minutes of Ischemia.
In conclusion, VF may develop at a lesser [K+]e rise and pHe fall in the presence of pinacidil during acute myocardial ischemia. PMID: 29743411 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Successful Retrieval of Entrapped Gaia Guidewire in Calcified Chronic Total Occlusion Using Rotational Atherectomy Device.
We report a novel technique for retrieving an entrapped Gaia guidewires in severely calcified coronary chronic total occlusion (CTO) using a rotational atherectomy device. By successfully cutting the entrapped and untangled guidewire within the CTO with the use of a rotational atherectomy device, we could effectively remove the Gaia guidewire from the right coronary artery. PMID: 29743412 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Quantitative Differentiation of LV Myocardium with and without Layer-Specific Fibrosis Using MRI in Hypertrophic Cardiomyopathy and Layer-Specific Strain TTE Analysis.
Authors: Funabashi N, Takaoka H, Ozawa K, Kamata T, Uehara M, Komuro I, Kobayashi Y Abstract To achieve further risk stratification in hypertrophic cardiomyopathy (HCM) patients, we localized and quantified layer-specific LVM fibrosis on MRI in HCM patients using regional layer-specific peak longitudinal strain (PLS) and peak circumferential strain (PCS) in LV myocardium (LVM) on speckle tracking transthoracic echocardiography (TTE). A total of 18 HCM patients (14 males; 58 ± 17 years) underwent 1.5T-MRI and TTE. PLS and PCS in each layer of the LVM (endocardium, epicardium, and whole-layer myocardium) were ...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Asn391Thr Mutation of β-Myosin Heavy Chain in a Hypertrophic Cardiomyopathy Family.
Asn391Thr Mutation of β-Myosin Heavy Chain in a Hypertrophic Cardiomyopathy Family. Int Heart J. 2018 May 09;: Authors: Feng X, He T, Wang JG, Zhao P Abstract The present study was performed to identify the genetic abnormalities in a family with familial hypertrophic cardiomyopathy.Peripheral blood samples were collected from 22 members of a Chinese family with hypertrophic cardiomyopathy and 307 healthy controls. A total of 26 candidate pathogenic genes were analyzed in the proband using targeted capture sequencing. Identified mutations were analyzed using Sanger sequencing in all family members ...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Management of Incomplete Initial Repair in the Treatment of Degenerative Mitral Insufficiency.
Authors: Ma W, Shi W, Zhang W, Wu W, Ye W, Kong Y Abstract We sought to present our institutional protocol to manage incomplete initial repair of degenerative mitral regurgitation and to evaluate its mid-term outcomes. Eight hundred and fifteen patients with degenerative mitral insufficiency undergoing mitral valve repair were investigated in this study. The initial repair attempt was incomplete in 48 patients, leaving a degree of residual regurgitation> mild, and an elevated transmitral gradient or systolic anterior motion (SAM). These patients were further treated with medication or mitral valve re-repair or r...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Hemodilution after Initial Treatment in Patients with Acute Decompensated Heart Failure.
Authors: Fujita T, Inomata T, Yazaki M, Iida Y, Kaida T, Ikeda Y, Nabeta T, Ishii S, Maekawa E, Yanagisawa T, Koitabashi T, Takeuchi I, Ako J Abstract Decongestion is an important goal of heart failure (HF) management. Blood cell concentration is a recognized indicator for guiding decongestive treatment for HF. We aimed to assess the clinical impact of hemodilution and hemoconcentration after initial treatment in acute decompensated HF (ADHF) patients. We retrospectively evaluated hemoglobin levels and body weight obtained before admission, on admission, 3 days after admission, and at discharge in 102 consecutive p...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis.
This study aimed to interpret the association between serum IS levels and coronary plaque burden (CPB) or CAC.A total of 30 consecutive patients on hemodialysis, who underwent 320-row coronary multidetector computed tomography (MDCT) angiography for suspected coronary artery disease, were enrolled in this prospective study. Coronary artery percent atheroma volume (a CPB marker) and percent calcium volume (a CAC marker) assessed using MDCT were evaluated. Furthermore, various oxidative and inflammatory markers typified by serum IS levels at a dialysis-free day were measured. Using these data, we investigated correlation bet...
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Minimally Invasive Aortic Valve Replacement Following Root Enlargement on too Narrow Annulus to Perform Transcatheter Aortic Valve Implantation.
This study concluded that minimally-invasive aortic valve replacement following root enlargement can be an option for the treatment of elderly patients with aortic stenosis accompanied by an annulus that is too small to perform transcatheter aortic valve implantation. PMID: 29743418 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - May 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Off-Pump Coronary Artery Bypass Grafting with Mini-Sternotomy in the Treatment of Triple-Vessel Coronary Artery Disease.
Authors: Su P, Gu S, Liu Y, Zhang X, Yan J, An X, Gao J, Xin Y, Zhou J Abstract We have developed off-pump coronary artery bypass approach with lower distal mini-sternotomy (TM-OPCAB) for multivessel coronary revascularization. The aim of this retrospective study is to provide evidence for the feasibility and safety of this technique in the treatment of triple-vessel diseases.Two hundred eighty-eight patients with triple-vessel coronary artery disease who underwent TM-OPCAB or standard off-pump coronary artery bypass surgery (S-OPCAB) were included in this study after propensity-score matching. We retrospectively r...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Recovery of Endothelial Function after Minor-to-Moderate Surgery Is Impaired by Diabetes Mellitus, Obesity, Hyperuricemia and Sevoflurane-Based Anesthesia.
Authors: Ohno S, Kohjitani A, Miyata M, Tohya A, Yamashita K, Hashiguchi T, Ohishi M, Sugimura M Abstract Endothelial dysfunction is observed in several cardiovascular diseases, where endothelium-dependent vasodilation is impaired by oxidative stress. However, the time course of endothelial function during the perioperative period of a minor-to-moderate surgery, and the effects of atherosclerotic risk factors and employed general anesthetics on recovery of endothelial function, are unknown. Endothelial function of 30 patients was evaluated as the reactive hyperemia index (RHI) of reactive hyperemia peripheral arter...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

MicroRNA-208a Regulates H9c2 Cells Simulated Ischemia-Reperfusion Myocardial Injury via Targeting CHD9 through Notch/NF-kappa B Signal Pathways.
In conclusion, miR-208a was a cardiac-enriched miRNA and CHD9 is a direct target of miR-208a, which was also related with Notch/NFB signal pathway during I/R injury. miR-208a has potential to be a biomarker for early diagnosis of I/R injury and might be used as a treatment target in clinical treatment of ischemic heart disease. PMID: 29681568 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

The Intra-Pericardial Paraganglioma Presenting as Ascites and Hemopericardium with Impending Tamponade.
Authors: Huang WC, Huang MH, Lu TM, Hsu CP Abstract The intra-pericardial paraganglioma is very rare and most of them present with hypertension or palpitations. Here we reported an extraordinarily rare case of intra-pericardial paraganglioma presenting as faint, pitting edema, abdominal fullness with ascites, and hemopericardium with impending tamponade, which was treated successfully by emergent pericardiocentesis and surgical resection. PMID: 29681569 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Single Femoral Venous Drainage Versus Both Vena Cava Drainage in Isolated Repeat Tricuspid Valve Surgery.
Authors: Peng R, Shi H, Ba J, Wang C Abstract To assess the potential advantages of minimally invasive surgery using a single femoral venous drainage method versus femoral venous and superior vena cava or jugular venous drainage method during repeat tricuspid valve surgery.From January 2010 to December 2016, 50 repeat tricuspid valve procedures were performed using a minimally invasive approach without aortic cross-clamping at our institution. The arterial cannula was inserted into the femoral artery, and at the same time, the venous cannula was placed in the femoral vein in 28 patients (FV group) during cardiopulm...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

The Outcome of Percutaneous Coronary Intervention for Significant Atherosclerotic Lesions in Segment Proximal to Myocardial Bridge at Left Anterior Descending Coronary Artery.
This study aimed to evaluate the efficacy of percutaneous coronary intervention (PCI) for significant atherosclerosis lesions proximal to myocardial bridge (MB) at left anterior descending coronary artery (LAD).A total of 330 consecutive patients with LAD significant stenosis, diagnosed as acute coronary syndrome (ACS), were included. Based on whether combined with MB, the patients were divided into the MB group (MB, n = 48) and non-MB group (NMB, n = 282). Drug eluting stents (DES) were successfully implanted in the stenostic segments prior to MB. All patients were followed up during the hospital stay, 30 days and 12 mont...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Improved Diagnosis of Detection of Late Enhancement in Left Ventricular Myocardium Using 2nd Generation 320-Slice CT Reconstructed with FIRST in Non-Ischemic Cardiomyopathy.
Authors: Takaoka H, Funabashi N, Ozawa K, Uehara M, Sano K, Komuro I, Kobayashi Y Abstract Forward Projected Model-based Iterative Reconstruction SoluTion (FIRST) is a new reconstruction technique using CT, which provides successful reconstruction of high-quality CT images, especially in low contrast imaging. To evaluate improvements in the diagnostic accuracy of the detection of abnormal late enhancement (LE) in left-ventricular myocardium (LVM) using 320-slice CT with FIRST, we compared this modality with previous CT methods in patients with non-ischemic cardiomyopathy or a cardiac tumor.This was a retrospective ...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Amlodipine Inhibits Vascular Cell Senescence and Protects Against Atherogenesis Through the Mechanism Independent of Calcium Channel Blockade.
Authors: Kayamori H, Shimizu I, Yoshida Y, Hayashi Y, Suda M, Ikegami R, Katsuumi G, Wakasugi T, Minamino T Abstract Vascular cells have a finite lifespan and eventually enter irreversible growth arrest called cellular senescence. We have previously suggested that vascular cell senescence contributes to the pathogenesis of human atherosclerosis. Amlodipine is a mixture of two enantiomers, one of which (S- enantiomer) has L-type channel blocking activity, while the other (R+ enantiomer) shows ~1000-fold weaker channel blocking activity than S- enantiomer and has other unknown effects. It has been reported that amlod...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Effect of Palliative Care for Patients with Heart Failure.
Authors: Xu Z, Chen L, Jin S, Yang B, Chen X, Wu Z Abstract Palliative care might be beneficial to heart failure. However, the results remain controversial. We conducted a systematic review and meta-analysis to explore the effect of palliative care on heart failure.PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of palliative care versus usual care on heart failure were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. The primary outco...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Sinus Standstill in a Patient after Intracoronary Papaverine Administration for a Coronary Fractional Flow Reserve.
Authors: Nauchi M, Sakai T, Yamawaki M, Ito Y Abstract A 78-year-old woman had paroxysmal atrial fibrillation and effort angina. Two months before she was admitted for a coronary angiography, she had been feeling dizzy. A Holter 24-hour electrocardiography monitor exhibited an asymptomatic episode of 2.9 seconds of RR interval. She underwent a coronary angiography, which showed intermediate stenosis in the left descending artery. Fractional flow reserve (FFR) measurement using intracoronary papaverine administration was performed. After intracoronary papaverine (12 mg) administration, pause of 4 seconds led to poly...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Clinical Meaning of the Ratio of Brachial Pre-Ejection Period to Brachial Ejection Time in Patients with Left Ventricular Systolic Dysfunction.
Authors: Park KH, Park WJ, Han SJ, Kim HS, Jo SH, Kim SA, Suh SW Abstract An increase in the ratio of the brachial pre-ejection period to brachial ejection time [pre-ejection period (PEP)/ET] is correlated with a decrease of left ventricular ejection fraction (LVEF). The current study was designed to test the hypothesis that the change value (Δ) of PEP/ET is a useful indicator of Δ LVEF in patients with left ventricular systolic dysfunction.We consecutively enrolled 104 patients with left ventricular systolic dysfunction (LVEF
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Carotid Artery Stenting Versus Carotid Endarterectomy for Treatment of Asymptomatic Carotid Artery Stenosis.
Authors: Yuan G, Zhou S, Wu W, Zhang Y, Lei J, Huang B Abstract Asymptomatic carotid stenosis is common and is associated with increased risk of stroke. The relative efficacy and safety of carotid endarterectomy (CEA) and carotid stenting (CAS) in patients with asymptomatic carotid stenosis remain unclear. Five studies that recruited patients with asymptomatic but significant carotid stenosis, who underwent CEA or CAS, were included in this systematic review and meta-analysis. The analyzed outcomes included risks of stroke, myocardial infarction (MI), and death. Risk ratio (RR) and 95% confidence interval (95% CI) ...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Spontaneous Reduction in Abnormal Myocardial Uptake of Fluorine-18 Fluorodeoxygluose in a Patient with Cardiac Sarcoidosis.
Authors: Terasaki F, Fujita SI, Kanzaki Y, Hirose Y, Ishizaka N Abstract Fluorine-18 fluorodeoxygluose (18F-FDG) positron emission tomography (PET) is a useful tool for evaluating disease activity in sarcoidosis including cardiac involvement. A 67-year-old patient who developed atrioventricular block requiring permanent pacemaker implantation was diagnosed with cardiac sarcoidosis. The patient did not undergo steroid or immunosuppressive therapy but underwent serial 18F-FDG PET examination, which showed spontaneous reduction in the myocardial FDG uptake, indicating the remission of immune-inflammatory activity. Alt...
Source: International Heart Journal - April 25, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Calcified Nodules Projecting into the Popliteal Artery Successfully Treated Through the Use of Myocardial Biopsy Forceps.
We report a case of critical limb ischemia with calcified nodules projecting into the popliteal artery, in which the use of myocardial biopsy forceps led to good results. PMID: 29628469 [PubMed - as supplied by publisher] (Source: International Heart Journal)
Source: International Heart Journal - April 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

A Rare Case of Rush Progression of Purulent Pericarditis by Escherichia coli in a Patient with Malignant Lymphoma.
We report an old male case of purulent pericarditis by Escherichia coli. He came to our hospital suffering from leg edema for 3 months. Echocardiography revealed the large amount of pericardial effusion, and he was admitted to test the cause of pericardial effusion without high fever, tachycardia, and shock vital signs. On the third day, he suddenly presented vital shock. We performed emergency cardiopulmonary resuscitation and pericardiocentesis. Appearance of pericardial effusion was hemorrhagic and purulent. The gram stain revealed remarkable E. coli invasion to pericardial space. Antibiotic therapy was immediately star...
Source: International Heart Journal - April 11, 2018 Category: Cardiology Tags: Int Heart J Source Type: research