The Predictive Factors Associated with In-Hospital Mortality of Melioidosis: A Cohort Study
Conclusions: Our study identified age, respiration rate, abnormal chest X-ray finding, and CO2 levels are predictive factors associated with in-hospital mortality in melioidosis patients. Physicians should be aware of these factors, have access to aggressive treatment options, and closely monitor patients with these risk factors.PMID:38674300 | PMC:PMC11052379 | DOI:10.3390/medicina60040654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Sunee Chayangsu Chusana Suankratay Apichat Tantraworasin Jiraporn Khorana Source Type: research
A Case of Thyroid Gland Abscess Caused by Brucella melitensis
Mikrobiyol Bul. 2024 Apr;58(2):217-223. doi: 10.5578/mb.20249810.ABSTRACTBrucellosis is a zoonotic disease endemic in many developing countries, including Türkiye. Among the species that are pathogenic for humans; Brucella melitensis is isolated from livestock animals like sheep and goats, Brucella abortus from cattle and Brucella suis from pigs. Laboratory diagnosis of infection caused by Brucella species with gram-negative coccobacillus morphology; can be made through characteristic culture features, serological tests and molecular methods. Brucellosis, which has a wide distribution of clinical signs and symptoms; can c...
Source: Mikrobiyoloji Bulteni - April 27, 2024 Category: Microbiology Authors: Ilgaz Kazaz Ertu ğrul Yazici İsmail Selçuk Aygar Tu ğrul Hoşbul Source Type: research
A comparative assessment of microbiocenosis of saliva and oropharynx in patients with migraine
CONCLUSION: A comparative assessment of the microbiota of a smear from the posterior wall of the oropharynx and saliva using MMSM showed the presence of dysbiosis both in the oropharynx and in the saliva of patients with migraine. However, there were fewer deviations from the norm in saliva, therefore, for diagnostic purposes, a smear from the posterior wall of the oropharynx is more significant as a biomarker for patients with migraine.PMID:38676678 | DOI:10.17116/jnevro202412404155 (Source: Herpes)
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: I L Naydenova A B Danilov A V Simonova A A Pilipovich E G Filatova Source Type: research
Acute Hepatitis of Unknown Origin in Children: Analysis of 17 Cases Admitted to the Bambino Ges ù Children's Hospital in Rome
This study described 17 cases of children admitted to the Bambino Gesù Children's Hospital with acute hepatitis of unknown origin between mid-April and November 2022. Following the World Health Organization's working case definition of probable cases, 17 children, with a median age of 2.1 years (interquartile range: 1.0-7.1), presenting with acute hepatitis non-AE, with serum transaminase >500 IU/L, were included in the study. A pre-specified set of microbiological tests was performed on different biological specimens for all pediatric patients. All patients resulted negative for the common hepatotropic viruses. The mo...
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Velia Chiara Di Maio Leonarda Gentile Rossana Scutari Luna Colagrossi Luana Coltella Stefania Ranno Giulia Linardos Daniela Liccardo Maria Sole Basso Andrea Pietrobattista Simona Landi Lorena Forqu é Marta Ciofi Degli Atti Lara Ricotta Andrea Onetti Muda Source Type: research
Isolation and Electrochemical Analysis of a Facultative Anaerobic Electrogenic Strain < em > Klebsiella < /em > sp. SQ-1
Pol J Microbiol. 2024 Apr 27. doi: 10.33073/pjm-2024-013. Online ahead of print.ABSTRACTElectricigens decompose organic matter and convert stored chemical energy into electrical energy through extracellular electron transfer. They are significant biocatalysts for microbial fuel cells with practical applications in green energy generation, effluent treatment, and bioremediation. A facultative anaerobic electrogenic strain SQ-1 is isolated from sludge in a biotechnology factory. The strain SQ-1 is a close relative of Klebsiella variicola. Multilayered biofilms form on the surface of a carbon electrode after the isolated bact...
Source: Polish Journal of Microbiology - April 27, 2024 Category: Microbiology Authors: Lei Zhou Tuoxian Tang Dandan Deng Yayue Wang Dongli Pei Source Type: research
Dissemination, virulence characteristic, antibiotic resistance determinants of emerging linezolid and vancomycin-resistant Enterococcus spp. in fish and crustacean
In conclusion, the emergence of linezolid-resistant -vancomycin-resistant enterococci recovered from Egyptian fish and shrimp, suggests that fish and seafood might participate a fundamental part in the emergence of antimicrobial resistance among humans.PMID:38677237 | DOI:10.1016/j.ijfoodmicro.2024.110711 (Source: International Journal of Food Microbiology)
Source: International Journal of Food Microbiology - April 27, 2024 Category: Food Science Authors: Sherief M Abdel-Raheem Sherin M Khodier Faisal Almathen Al-Shaimaa T Hanafy Sarah M Abbas Salah Abdulaziz Al-Shami Saad Ibrahim Al-Sultan Ahmed Alfifi Reham M El-Tarabili Source Type: research
The role of rcpA gene in regulating biofilm formation and virulence in Vibrio parahaemolyticus
In conclusion, rcpA plays a role in determining biofilm formation and virulence of V. parahaemolyticus and further research is necessitated to fully understand its function in V. parahaemolyticus.PMID:38677238 | DOI:10.1016/j.ijfoodmicro.2024.110714 (Source: International Journal of Food Microbiology)
Source: International Journal of Food Microbiology - April 27, 2024 Category: Food Science Authors: Wenxiu Zhu Jiaxiu Liu Yingying Zhang Dongyun Zhao Shugang Li Hanzheng Dou Haisong Wang Xiaodong Xia Source Type: research
Genome and secretome insights: unravelling the lignocellulolytic potential of Myceliophthora verrucosa for enhanced hydrolysis of lignocellulosic biomass
Arch Microbiol. 2024 Apr 27;206(5):236. doi: 10.1007/s00203-024-03974-w.ABSTRACTLignocellulolytic enzymes from a novel Myceliophthora verrucosa (5DR) strain was found to potentiate the efficacy of benchmark cellulase during saccharification of acid/alkali treated bagasse by ~ 2.24 fold, indicating it to be an important source of auxiliary enzymes. The De-novo sequencing and analysis of M. verrucosa genome (31.7 Mb) revealed to encode for 7989 putative genes, representing a wide array of CAZymes (366) with a high proportions of auxiliary activity (AA) genes (76). The LC/MS QTOF based secretome analysis of M. verrucosa showe...
Source: Archives of Microbiology - April 27, 2024 Category: Microbiology Authors: Gaurav Sharma Baljit Kaur Varinder Singh Yashika Raheja Marcos Di Falco Adrian Tsang Bhupinder Singh Chadha Source Type: research
Oerskovia flava sp. nov., a deoxynivalenol (DON)-degrading actinomycete isolated from the rhizosphere soil of long-term continuous cropping cucumber
Antonie Van Leeuwenhoek. 2024 Apr 27;117(1):73. doi: 10.1007/s10482-024-01972-y.ABSTRACTThe deoxynivalenol (DON)-degrading bacterium JB1-3-2 T was isolated from a rhizosphere soil sample of cucumber collected from a greenhouse located in Zhenjiang, Eastern China. The JB1-3-2 T strain is a Gram-stain-positive, nonmotile and round actinomycete. Growth was observed at temperatures between 15 and 40 ℃ (optimum, 35 ℃), in the presence of 15% (w/v) NaCl (optimum, 3%), and at pH 3 and 11 (optimum, 7). The major cellular fatty acids identified were anteiso-C15:0, iso-C16:0 and anteiso-C17:0. Genome sequencing revealed a genome...
Source: Antonie van Leeuwenhoek - April 27, 2024 Category: Microbiology Authors: Wei Wei Wenjun Guo Biyue Yang Kaili Wang Xinyu Hu Guanya Ji Xiangru Xu Shenkui Liu Lin Zhu Source Type: research
Phage transmission strategies: are phages farming their host?
Curr Opin Microbiol. 2024 Apr 26;79:102481. doi: 10.1016/j.mib.2024.102481. Online ahead of print.ABSTRACTExtensive coevolution has led to utterly intricate interactions between phages and their bacterial hosts. While both the (short-term) intracellular molecular host-subversion mechanisms during a phage infection cycle and the (long-term) mutational arms race between phages and host cells have traditionally received a lot of attention, there has been an underestimating neglect of (mid-term) transmission strategies by which phages manage to cautiously spread throughout their host population. However, recent findings unders...
Source: Current Opinion in Microbiology - April 27, 2024 Category: Microbiology Authors: Yorben Casters Leonard E B äcker Kevin Broux Abram Aertsen Source Type: research
Staphylococcus aureus membrane vesicles: an evolving story
Trends Microbiol. 2024 Apr 26:S0966-842X(24)00088-X. doi: 10.1016/j.tim.2024.04.003. Online ahead of print.ABSTRACTStaphylococcus aureus is an important bacterial pathogen that causes a wide variety of human diseases in community and hospital settings. S. aureus employs a diverse array of virulence factors, both surface-associated and secreted, to promote colonization, infection, and immune evasion. Over the past decade, a growing body of research has shown that S. aureus generates extracellular membrane vesicles (MVs) that package a variety of bacterial components, many of which are virulence factors. In this review, we s...
Source: Trends in Microbiology - April 27, 2024 Category: Microbiology Authors: Xiaogang Wang Jean C Lee Source Type: research
Modular metabolic engineering of Bacillus amyloliquefaciens for high-level production of green biosurfactant iturin A
This study laid a foundation for industrial production and application development of iturin A, and provided the guidance of metabolic engineering breeding for efficient production of other metabolites synthesized by non-ribosomal peptide synthetase. KEY POINTS: • Optimizing 5'-UTR is an effective tactics to regulate synthetase cluster expression. • Blocking 1-DNJ synthesis benefited corn starch utilization and iturin A production. • The iturin A yield attained in this work was the highest yield reported so far.PMID:38676716 | DOI:10.1007/s00253-024-13083-9 (Source: Applied Microbiology and Biotechnology)
Source: Applied Microbiology and Biotechnology - April 27, 2024 Category: Microbiology Authors: Menglin She Huijuan Zhou Wanrong Dong Yuxiang Xu Lin Gao Jiaming Gao Yong Yang Zhifan Yang Dongbo Cai Shouwen Chen Source Type: research
The Predictive Factors Associated with In-Hospital Mortality of Melioidosis: A Cohort Study
Conclusions: Our study identified age, respiration rate, abnormal chest X-ray finding, and CO2 levels are predictive factors associated with in-hospital mortality in melioidosis patients. Physicians should be aware of these factors, have access to aggressive treatment options, and closely monitor patients with these risk factors.PMID:38674300 | DOI:10.3390/medicina60040654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Sunee Chayangsu Chusana Suankratay Apichat Tantraworasin Jiraporn Khorana Source Type: research
Investigation of Cytotoxic and Antileishmanial Activity of Hybrid Silver Nanoparticle Complexes: Potential Drug Candidates against Leishmania Species
In this study, it was aimed to investigate the cytotoxic and in vitro antileishmanial activity of hybrid silver nanoparticle (AgNP) complexes. In this study, three types of nanoparticles (NPs), oxidized amylose-silver (OA-Ag) NPs, oxidized amylose-curcumin (OA-Cur) NPs and oxidized amylose-curcumin-silver (OA-CurAgNP) nanoparticles were synthesized. The cytotoxic activity of the synthesized nanoparticles was determined against L929 mouse fibroblasts and the in vitro antileishmanial activity was determined against Leishmania tropica, Leishmania infantum and Leishmania donovani isolates by the broth microdilution method. It ...
Source: Mikrobiyoloji Bulteni - April 27, 2024 Category: Microbiology Authors: Yener Özel İbrahim Çavuş Umut Yilmaz Feyzullah Tokay Sema Ba ğdat Ahmet Özbilgin Mehmet Ünlü G ülhan Vardar Ünlü Source Type: research
Comparison of Three Different Methods in Investigating the Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates
In conclusion, MALDI-TOF MS may not function as a gold standard method like PFGE and MLST for epidemiological analysis in A.baumannii species and the epidemiological typing protocols used for MALDI-TOF MS need to be improved and developed.PMID:38676579 | DOI:10.5578/mb.202498131 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - April 27, 2024 Category: Microbiology Authors: G ülşen Uluçam Atay G ülçin Bayramoğlu İlknur Tosun Ülkü Ünsal Source Type: research
