LC‐MS‐based Metabolite Profiling of Methanolic Extracts from the Medicinal and Aromatic Species Mentha pulegium and Origanum majorana
ConclusionThe distribution of phenolic compounds in the methanolic extract showed a variation among studied plants. Mentha pulegium can be considered as a source of gallocatechin. Copyright © 2015 John Wiley & Sons, Ltd. (Source: Phytochemical Analysis)
Source: Phytochemical Analysis - May 15, 2015 Category: Biochemistry Authors: Amani Taamalli, David Arráez‐Román, Leila Abaza, Ihsan Iswaldi, Alberto Fernández‐Gutiérrez, Mokhtar Zarrouk, Antonio Segura‐Carretero Tags: Research Article Source Type: research
A Bayesian Approach to Social Structure Uncovers Cryptic Regulation of Group Dynamics in Drosophila melanogaster
Brad R. Foley, Julia B. Saltz, Sergey V. Nuzhdin and Paul Marjoram,
The American Naturalist, Volume 0, Issue 0, Page 000, Ahead of Print. (Source: The American Naturalist)
Source: The American Naturalist - April 16, 2015 Category: Zoology Tags: article Source Type: research
Microbiological quality of selected spices and herbs including the presence of Cronobacter spp.
Abstract
The cultivation of spices and herbs in parts of the world characterized by warm climate and high humidity provides excellent conditions for the development of microorganisms, including the undesirable ones. The aim of this study was to determine the microbiological quality of spices and herbs available on the Polish market, considering the occurrence of Cronobacter species bacteria. Analyses covered 60 samples of commercial spices and herbs, including 38 samples of dried herbs (basil, bay leaves, thyme, oregano, tarragon, marjoram, dill, parsley, rosemary, lovage) and 16 samples of seasoning blend...
Source: Food Microbiology - April 8, 2015 Category: Food Science Authors: Garbowska M, Berthold-Pluta A, Stasiak-Różańska L Tags: Food Microbiol Source Type: research
Phylloquinone content of herbs, spices and seasonings
In this study, we analyzed the phylloquinone content of a large number of commonly available culinary herbs, spices, and seasonings. Samples of fresh herbs (n =19), dried herbs (n =28), spices and seeds (n =26), seasoning blends (n =9), and other flavor enhancers (n =11) were purchased in Montreal (Quebec, Canada) and Washington (DC, USA). All samples were analyzed in quadruplicate using standardized HPLC procedures. Most fresh herbs contained between 450 and 1200μg of phylloquinone/100g. Dried herbs were even richer with some (cilantro, marjoram, parsley) showing concentrations of ≈3000μg/100g. Phylloquinone content o...
Source: Journal of Food Composition and Analysis - March 8, 2015 Category: Food Science Source Type: research
The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications
Abstract
Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots, wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and neuroprotective effects as well as the ability to reduce reactive oxygen species, protect the blood-brain barrier, modulate mitochondrial function, and regulate apoptosis. Considering these pharmaceutical characteristics, pinocembrin has potential as a drug to treat ischemic stroke and other clinical conditions. In this review, we summarize its pharmacologic characteristics and discuss its mechanisms of action and pot...
Source: Molecular Neurobiology - March 6, 2015 Category: Neurology Source Type: research
Epigenetic regulation of inflammation [Developmental Biology]
The intestinal epithelium forms a barrier protecting the organism from microbes and other proinflammatory stimuli. The integrity of this barrier and the proper response to infection requires precise regulation of powerful immune homing signals such as tumor necrosis factor (TNF). Dysregulation of TNF leads to inflammatory bowel diseases (IBD), but... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - March 3, 2015 Category: Science Authors: Marjoram, L., Alvers, A., Deerhake, M. E., Bagwell, J., Mankiewicz, J., Cocchiaro, J. L., Beerman, R. W., Willer, J., Sumigray, K. D., Katsanis, N., Tobin, D. M., Rawls, J. F., Goll, M. G., Bagnat, M. Tags: Biological Sciences Source Type: research
Metastatic spinal deposits or bovine tuberculosis infection?
Non-invasive bladder tumours have been treated with resection followed by intravesical Bacillus Calmette-Guerin (BCG) instillation since 1976. It is believed to exert its anti-tumour activity via local modulation of immune responses, which results in inflammation and subsequent elimination of malignant cells. Orthopaedic complications of this therapy are uncommon and include myco-bacterial osteomyelitis and reactive arthritis. There have been 5 previous published cases of spinal disc infection following BCG treatment making it a very rare complication. (Source: The Spine Journal)
Source: The Spine Journal - February 21, 2015 Category: Orthopaedics Authors: Tom Marjoram, Saajid Kaleel Source Type: research
A Big Bang model of human colorectal tumor growth
Nature Genetics 47, 209 (2015).
doi:10.1038/ng.3214
Authors: Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, Trevor A Graham, Matthew P Salomon, Junsong Zhao, Paul Marjoram, Kimberly Siegmund, Michael F Press, Darryl Shibata & Christina Curtis (Source: Nature Genetics)
Source: Nature Genetics - February 9, 2015 Category: Genetics & Stem Cells Authors: Andrea SottorivaHaeyoun KangZhicheng MaTrevor A GrahamMatthew P SalomonJunsong ZhaoPaul MarjoramKimberly SiegmundMichael F PressDarryl ShibataChristina Curtis Tags: Article Source Type: research
The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomised controlled pilot study
ConclusionsThe results obtained in the present study show the beneficial effects of marjoram tea on the hormonal profile of PCOS women because it was found to improve insulin sensitivity and reduce the levels of adrenal androgens. Further research is needed to confirm these results and to investigate the active components and mechanisms contributing to such potential beneficial effects of marjoram herb. (Source: Journal of Human Nutrition and Dietetics)
Source: Journal of Human Nutrition and Dietetics - February 9, 2015 Category: Nutrition Authors: I. Haj‐Husein, S. Tukan, F. Alkazaleh Tags: Research Paper Source Type: research
The Antimicrobial Effect of Spice‐Based Marinades against Campylobacter jejuni on Contaminated Fresh Broiler Wings
Abstract
The antimicrobial effect of spice‐based marinades against Campylobacter jejuni on inoculated fresh broiler wings was investigated. Experiments were carried out with 1 strain of C. jejuni and 6 marinades. Four experimental marinades were composed for the study and contained spices (thyme, rosemary, basil, marjoram, and so on) and different combination of bioactive compounds. Two marinades were commercial and contained spices (black pepper, sweet red pepper, and so on) and chemical additives (monosodium glutamate, sodium diacetate, calcium lactate), 1 commercial marinade was also enriched with bioactive compounds ...
Source: Journal of Food Science - January 27, 2015 Category: Food Science Authors: Gintarė Zakarienė, Anita Rokaitytė, Sigita Ramonaitė, Aleksandr Novoslavskij, Kristina Mulkytė, Gintarė Zaborskienė, Mindaugas Malakauskas Tags: M: Food Microbiology & Safety Source Type: research
Development of a chicken feet protein film containing essential oils
Publication date: April 2015 Source:Food Hydrocolloids, Volume 46 Author(s): Ji-Hyun Lee , Jihyeon Lee , Kyung Bin Song To prepare an edible film, after extraction of protein from chicken feet, chicken feet protein (CP) films were prepared using various types of plasticizers, and their physical properties were evaluated. Incorporating more sorbitol than glycerol as a plasticizer in the CP film made the film more rigid, and a 3:2 ratio (w/w) of glycerol-sorbitol was optimal. To render the film antimicrobial and antioxidative, marjoram (MA), coriander (CO), and clove bud oil (CL) were incorporated. The type of essenti...
Source: Food Hydrocolloids - January 20, 2015 Category: Food Science Source Type: research
α2β1 Integrin, GPVI Receptor, and Common FcRγ Chain on Mouse Platelets Mediate Distinct Responses to Collagen in Models of Thrombosis
Conclusion Our data demonstrate that genetic deletion of GPVI receptor, FcRγ chain, or the α2β1 integrin changes the thrombotic potentials of these platelets to collagen dependent on the stimulus mechanism. The data suggest that the FcRγ chain may provide a dominant negative effect through modulating signaling pathways in platelets involving several tyrosine phosphorylated proteins such as RhoGDI. In addition, these findings suggest a more complex signaling network downstream of the platelet collagen receptors than previously appreciated. (Source: PLoS One)
Source: PLoS One - November 21, 2014 Category: Biomedical Science Authors: Robin J. Marjoram et al. Source Type: research
Occurrence of Stachybotrys chartarum chemotype S in dried culinary herbs
The objective of the present study was to examine selected dried culinary herbs for the presence of S. chartarum chemotype S, to assess the potential risk of a contamination of foods with macrocyclic trichothecenes. In total, 50 Stachybotrys isolates from different types of culinary herbs (n = 100) such as marjoram (Origanum majorana Linné (L.)), oregano (Origanum vulgare L.), thyme (Thymus vulgaris L.), and savory (Satureja hortensis L.) were examined by MTT-cell culture test (effect-based bioassay), ELISA, and by liquid chromatography tandem mass spectrometry (LC-MS/MS). Selected toxic and non-toxic isolates (n =...
Source: Mycotoxin Research - October 28, 2014 Category: Toxicology Source Type: research
Antioxidant, antityrosinase and antibacterial properties of fresh and processed leaves of Anacardium occidentale and Piper betle
In this study, the antioxidant, antityrosinase and antibacterial properties of fresh and processed leaves of Anacardium occidentale (cashew) and Piper betle (betel) were analysed and evaluated. For assessing antioxidant properties (AOP) of total phenolic content, total flavonoid content, caffeoylquinic acid content, free radical scavenging activity, ferric reducing power and ferrous ion chelating ability, the Folin–Ciocalteu, aluminium chloride, molybdate, DPPH radical scavenging, potassium ferricyanide and ferrozine assays were used, respectively. Antityrosinase and antibacterial properties were determined using the res...
Source: Food Bioscience - October 20, 2014 Category: Food Science Source Type: research
Native American Ancestry Is Associated With Severe Diabetic Retinopathy in Latinos [Genetics]
Conclusions.
Our results demonstrate for the first time to our knowledge that NAA is a significant risk factor for severe DR in Latinos. (Source: Investigative Ophthalmology)
Source: Investigative Ophthalmology - September 25, 2014 Category: Opthalmology Authors: Gao, X., Gauderman, W. J., Marjoram, P., Torres, M., Chen, Y.-D. I., Taylor, K. D., Rotter, J. I., Varma, R. Tags: Genetics Source Type: research
