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 In vitro Anti-Leishmanial Activity of Essential Oils Extracted from Plants Growing in Northern Cyprus Against Leishmania tropica 
CONCLUSION: All tested essential oils inhibited promastigotes of Leishmania tropica. OD essential oil demonstrated the highest anti-leishmanial activity.AMAÇ: Bitkilerden elde edilen doğal ürünlerin leishmaniasis tedavisi için yeni ve etkili bileşiklerin üretilmesine öncülük edeceği düşünülmektedir. Çalışmamızda, Kuzey Kıbrıs’ta yetişen Origanum dubium (OD), Origanum majorana (OM), Salvia fruticosa (SF) ve Laurus nobilis (LN) bitkilerinden elde edilen uçucu yağların Leishmania tropica’ya karşı in vitro etkinlikleri araştırılmıştır.YÖNTEMLER: Çalışmamızda, Leishmania tropica suşu (...
Source: Turkish Society for Parasitology - June 9, 2021 Category: Parasitology Authors: Emrah G üler Ahmet Özbilgin İbrahim Çavuş Buket Baddal İlker Etikan K. H üsnü Can Başer Tamer Şanlıdağ Source Type: research

Molecules, Vol. 26, Pages 3356: A Study on the Phytotoxic Potential of the Seasoning Herb Marjoram (Origanum majorana L.) Leaves
Macías In the search of new alternatives for weed control, spices appear as an option with great potential. They are rich in bioactive natural products and edible, which might minimize toxicity hazard. Marjoram (Origanum majorana L.) is an aromatic herb that has been widely employed as a seasoning herb in Mediterranean countries. Although marjoram boasts a plethora of therapeutic properties (painkiller, antibiotic, treatment for intestinal disorders, etc.), the potential for its extracts for weed control is still to be more thoroughly explored. In order to determine their phytotoxic potential, marjoram leaves were sub...
Source: Molecules - June 2, 2021 Category: Chemistry Authors: Antonio Cala Jos é R. Salcedo Ascensi ón Torres Rosa M. Varela Jos é M. G. Molinillo Francisco A. Mac ías Tags: Article Source Type: research

Antioxidant and Anti-Inflammatory Effects of Origanum majorana L. Methanolic Extract on Bile Duct Ligation in Male Rats
CONCLUSIONS: The results of the present study showed that oral administration of OM extract had a moderate protective effect on cholestasis due to BDL. Indeed, more studies with different doses of extract are needed to confirm this finding.PMID:34035827 | PMC:PMC8121572 | DOI:10.1155/2021/9927196 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - May 26, 2021 Category: Complementary Medicine Authors: Izadpanah Gheitasi Nikta Motaghi Hossein Sadeghi Heibatollah Sadeghi Zahra Moslemi Mahdieh Eftekhari Nasrin Shakerinasab Amir Hossein Doustimotlagh Source Type: research

Ethnobotanical survey about medicinal plants used in traditional treatment of insomnia, asthenia, and oral and gum infections in the region Fez-Meknes, Morocco
Environ Sci Pollut Res Int. 2021 May 24. doi: 10.1007/s11356-021-14439-8. Online ahead of print.ABSTRACTAn ethnobotanical survey was conducted among herbalists in the north-central region of Morocco using a questionnaire in order to highlight knowledge and know-how and to establish an inventory of herbal remedies used in the treatment of diseases common in the region and rarely cited in the bibliography: in this case, it is insomnia, asthenia, and oral-gum infections. The results showed that 120 herbalists were interviewed in different areas of the Fez-Meknes region, about 86 species were cited and grouped into 60 families...
Source: Environmental Science and Pollution Research International - May 25, 2021 Category: Environmental Health Authors: Ghada Beniaich Rajae Salim Elhachmia Ech-Chihbi Fadoua El-Hajjaji Zakia Rais Abdelfattah Abdellaoui Mustapha Taleb Source Type: research

High-frequency in vitro propagation and assessment of genetic uniformity and micro-morphological characterization of Origanum majorana L. –A highly traded aromatic herb
Publication date: Available online 8 May 2021Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Dulam Sandhya, Phanikanth Jogam, Manokari M, Mahipal S. Shekhawat, Jyoti Singh Jadaun, Venkateswar Rao Allini, Sadanandam Abbagani (Source: Biocatalysis and Agricultural Biotechnology)
Source: Biocatalysis and Agricultural Biotechnology - May 8, 2021 Category: Biotechnology Source Type: research

Molecules, Vol. 26, Pages 2354: Evaluation of Seven Essential Oils as Seed Treatments against Seedborne Fungal Pathogens of Cucurbita maxima
Romanazzi Essential oils are gaining interest as environmentally friendly alternatives to synthetic fungicides for management of seedborne pathogens. Here, seven essential oils were initially tested in vivo for disinfection of squash seeds (Cucurbita maxima) naturally contaminated by Stagonosporopsis cucurbitacearum, Alternaria alternata, Fusarium fujikuro, Fusarium solani, Paramyrothecium roridum, Albifimbria verrucaria, Curvularia spicifera, and Rhizopus stolonifer. The seeds were treated with essential oils from Cymbopogon citratus, Lavandula dentata, Lavandula hybrida, Melaleuca alternifolia, Laurus nobilis, and Or...
Source: Molecules - April 18, 2021 Category: Chemistry Authors: Marwa Moumni Mohamed Bechir Allagui Kaies Mezrioui Hajer Ben Amara Gianfranco Romanazzi Tags: Article Source Type: research

Origanum majorana L. Extract Protects Against Isoproterenol-Induced Cardiotoxicity in Rats
Cardiovasc Toxicol. 2021 Mar 30. doi: 10.1007/s12012-021-09645-2. Online ahead of print.ABSTRACTCoronary artery diseases are the major causes of disabilities and death worldwide. Evidence from the literature has demonstrated that Origanum majorana L. (marjoram) acts as an antioxidant, anti-inflammatory, antiplatelet, and assists in hormonal regulation. However, there is limited scientific evidence describing the signaling pathways associated with the marjoram's positive effect on cardiac injury. Therefore, we aimed to understand the mechanistic protective effects of marjoram on isoproterenol (ISO)-induced myocardial injury...
Source: Cardiovascular Toxicology - March 31, 2021 Category: Cardiology Authors: Abeer M Rababa'h Miya A Alzoubi Source Type: research

Bayesian parameter estimation for automatic annotation of gene functions using observational data and phylogenetic trees
by George G. Vega Yon, Duncan C. Thomas, John Morrison, Huaiyu Mi, Paul D. Thomas, Paul Marjoram Gene function annotation is important for a variety of downstream analyses of genetic data. But experimental characterization of function remains costly and slow, making computational prediction an important endeavor. Phylogenetic approaches to prediction have been developed, but implementation of a practical Bayesian framework for parameter estimation remains an outstanding challenge. We have developed a computationally efficient model of evolution of gene annotations using phylogenies based on a Bayesian framework using Mark...
Source: PLoS Computational Biology - February 18, 2021 Category: Biology Authors: George G. Vega Yon Source Type: research

Polyphasic study of antibiotic-resistant enterobacteria isolated from fresh produce in Germany and description of Enterobacter vonholyi sp. nov. isolated from marjoram and Enterobacter dykesii sp. nov. isolated from mung bean sprout.
This study thus accurately identified the enterobacteria from fresh produce as species belonging to the genera Citrobacter, Enterobacter, Escherichia and Klebsiella, but also showed that these can carry potentially transferable antibiotic resistance genes and may thus contribute to the spread of these via the food route. PMID: 33370657 [PubMed - as supplied by publisher] (Source: Systematic and Applied Microbiology)
Source: Systematic and Applied Microbiology - December 17, 2020 Category: Microbiology Authors: Cho GS, Stein M, Fiedler G, Igbinosa EO, Koll LP, Brinks E, Rathje J, Neve H, Franz CMAP Tags: Syst Appl Microbiol Source Type: research