Origanum majorana L. protects against neuroinflammation-mediated cognitive impairment: a phyto-pharmacological study
Neuroinflammation and oxidative stress are critical players in the pathogenesis of numerous neurodegenerative diseases, such as Alzheimer ’s disease (AD) which is responsible for most cases of dementia in the e... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - May 20, 2023 Category: Complementary Medicine Authors: Reham Wagdy, Reham M. Abdel-Kader, Ahmed H. El-Khatib, Michael W. Linscheid, Heba Handoussa and Nabila Hamdi Tags: Research article Source Type: research
Molecules, Vol. 28, Pages 3714: Essential Oil Composition and Antioxidant Activity of Oregano and Marjoram as Affected by Different Light-Emitting Diodes
In this study, different spectra of LED light, namely blue, red, white, blue-red, and natural ambient light as a control, were applied to assess the essential oil content, composition, flavonoid, phenolic, and antioxidant capacity of oregano and marjoram. GC-MS analysis revealed thymol, terpinen-4-ol, sabinene, linalool, p-cymene, and γ-terpinene as the main compounds. In oregano, the thymol content ranged from 11.91% to 48.26%, while in marjoram it varied from 17.47% to 35.06% in different samples. In oregano and marjoram, the highest phenolic contents were in blue (61.26 mg of tannic acid E/g of DW) and in ...
Source: Molecules - April 25, 2023 Category: Chemistry Authors: Danial Sarfaraz Mehdi Rahimmalek Mohammad R. Sabzalian Shima Gharibi Adam Matkowski Antoni Szumny Tags: Article Source Type: research
Elaboration and general evaluation of chitosan-based films containing terpene alcohols-rich essential oils
AbstractRecently, the scientific community is interested in the synthesis of biodegradable and bioactive packaging to replace oil-based ones. Therefore, the present study aims to elaborate an active and biodegradable material using chitosan (CS-film) combined with pelargonium, tea tree, marjoram, and thyme essential oils (EOs), and then evaluate their different properties and biological activities. The obtained data showed an augmentation in CS-film thickness and opacity following the addition of EOs ranging from 17 ± 3 to 42 ± 2 μm and from 1.53 ± 0.04 to 2.67 ± 0.09, respectively. Furthermore, a si...
Source: World Journal of Microbiology and Biotechnology - April 4, 2023 Category: Microbiology Source Type: research
Comparison of lung cancer staging data from Bradford and Craven (B & C) Targeted Lung Health Check (TLHC) programme with national statistics
(Source: Lung Cancer)
Source: Lung Cancer - April 1, 2023 Category: Cancer & Oncology Authors: Bethany Marjoram, LiJi Ng, Leanne Cheyne Tags: Screening Source Type: research
Reporting of coronary artery calcification in targeted lung health check: Bradford and Craven and North Kirklees programmes
(Source: Lung Cancer)
Source: Lung Cancer - April 1, 2023 Category: Cancer & Oncology Authors: LiJi Ng, Beth Marjoram, Lucy Ashton, Graham Bowmer, Tracy Hiley, Jon Martin, Phillip Marjoram, Mark Kon, Christopher Marshall, Leanne Cheyne Tags: Screening Source Type: research
Molecules, Vol. 28, Pages 2007: Toxicity and Physiological Effects of Nine Lamiaceae Essential Oils and Their Major Compounds on Reticulitermes dabieshanensis
Dayu Zhang
The volatile metabolites of Salvia sclarea, Rosmarinus officinalis, Thymus serpyllum, Mentha spicata, Melissa officinalis, Origanum majorana, Mentha piperita, Ocimum basilicum and Lavandula angustifolia were determined by gas chromatography–mass spectrometry. The vapor insecticidal properties of the analyzed essential oils and their compounds were screened using Reticulitermes dabieshanensis workers. The most effective oils were S. sclarea (major constituent linalyl acetate, 65.93%), R. officinalis (1,8-cineole, 45.56%), T. serpyllum (thymol, 33.59%), M. spicata (carvone, 58.68%), M. officin...
Source: Molecules - February 21, 2023 Category: Chemistry Authors: Xi Yang Chunzhe Jin Ziwei Wu Hui Han Zhilin Zhang Yongjian Xie Dayu Zhang Tags: Article Source Type: research
Microencapsulation of marjoram essential oil as a food additive using sodium alginate and whey protein isolate
This study aimed to evaluate the influence of process variables on the microencapsulation of marjoram essential oil (MEO) (Origanum majorana L.) by ionic gelation. The effect of sodium alginate concentration (0.5-2 g/100 mL), emulsifier concentration (0.5-2 g/100 mL whey protein isolate (WPI)), and cationic bath concentration (0.05-0.3 mol/L CaCl2) on the emulsions and beads properties were investigated, according to a rotatable central composite design. MEO chemical composition and antimicrobial activity were assessed. Emulsions were characterized for droplet size and viscosity, while the particles were analyzed for encap...
Source: International Journal of Biological Macromolecules - February 3, 2023 Category: Biochemistry Authors: Karen Elbert Leal Mazza Andr é Mesquita Magalhães Costa Janine Passos Lima da Silva Daniela Sales Alviano Humberto Ribeiro Bizzo Renata Valeriano Tonon Source Type: research
IJERPH, Vol. 20, Pages 2701: The Toxicological Risk Assessment of Dermal Exposure of Patients Exposed to Lead and Cadmium Due to Application of Ointments with Marjoram Herb Extract (Majoranae herbae extractum)
ak
Potential heavy metal impurities (HMI) in pharmaceuticals/pharmaceutical products/drugs based on plant raw materials (e.g., herbs) are an important problem in the pharmaceutical industry; however, there is a lack of scientific articles on the comprehensive toxicological risk assessment of HMI in ointment applied dermally. To make the appropriate toxicological risk assessment, we consider: (1) the raw results of the levels of lead and cadmium in the ointments (metal per kg of mass), (2) one-time administration of the applied ointment, (3) daily exposure of Pb and Cd in the applied ointments according to the maximum d...
Source: International Journal of Environmental Research and Public Health - February 2, 2023 Category: Environmental Health Authors: Kamil Jurowski Miros ław Krośniak Tags: Article Source Type: research
Optimizing the Antimicrobial Synergism of Melaleuca alternifolia (Tea Tree) Essential Oil Combinations for Application against Respiratory Related
Pathogens
This study aimed to determine the antimicrobial activity of four essential
oil combinations, all inclusive of M. alternifolia, against nine pathogens associated with the respiratory tract. The minimum inhibitory concentration assay was used to determine the
antimicrobial activity of four essential oil combinations, M. alternifolia in combination with Cupressus sempervirens, Origanum majorana, Myrtus communis, and Origanum
vulgare essential oils. The interactions between essential oil combinations were analyzed using isobolograms and SynergyFinder 2.0 software to visualize the synergistic potential at
...
Source: Planta Medica - January 10, 2023 Category: Drugs & Pharmacology Authors: Rapper, Stephanie Leigh-de Viljoen, Alvaro van Vuuren, Sandy Tags: Original Papers Source Type: research
Genes, Vol. 13, Pages 1844: Evaluation of the Maturity and Gene Expression of Sheep Oocytes and Embryos Cultured in Media Supplemented with Marjoram (Origanum vulgare) Extract
This study aimed to evaluate the effects of marjoram extract on oocyte maturation and gene expression in sheep oocytes and embryos. The first experiment studied the effect of the extract as an antioxidant to improve the in vitro maturation media used for sheep oocytes; the oocytes were matured in a TCM199 medium supplemented with 1 or 10 µg/mL of marjoram extract or the control, 0 µg, for 24 hr. Then, the maturation was estimated, and the gene expression was measured by using qPCR. The second experiment studied the effect of the extract on the development of sheep embryos produced in vitro; the ...
Source: Genes - October 12, 2022 Category: Genetics & Stem Cells Authors: Mashael M. Alotaibi Ahmad R. Alhimaidi Muath Q. Al-Ghadi Aiman A. Ammari Nawal M. Al-Malahi Tags: Article Source Type: research
Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo
Biomed Pharmacother. 2022 Sep 28;155:113762. doi: 10.1016/j.biopha.2022.113762. Online ahead of print.ABSTRACTCurrent targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage of patients responding to these treatments. This situation has prompted us to investigate the anticancer potential of the Origanum majorana Essential Oil (OMEO). In this pre-clinical study and using two major human NSCLC, namely A549 and LNM35, we demonstrated that OMEO significantly decreases the viability of these cells and the growth of their pre-formed col...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Kholoud Arafat Shahrazad Sulaiman Aya Mudhafar Al-Azawi Javed Yasin Subi Sugathan Abderrahim Nemmar Sherif Karam Samir Attoub Source Type: research
Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo
Biomed Pharmacother. 2022 Sep 28;155:113762. doi: 10.1016/j.biopha.2022.113762. Online ahead of print.ABSTRACTCurrent targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage of patients responding to these treatments. This situation has prompted us to investigate the anticancer potential of the Origanum majorana Essential Oil (OMEO). In this pre-clinical study and using two major human NSCLC, namely A549 and LNM35, we demonstrated that OMEO significantly decreases the viability of these cells and the growth of their pre-formed col...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Kholoud Arafat Shahrazad Sulaiman Aya Mudhafar Al-Azawi Javed Yasin Subi Sugathan Abderrahim Nemmar Sherif Karam Samir Attoub Source Type: research
Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo
Biomed Pharmacother. 2022 Sep 28;155:113762. doi: 10.1016/j.biopha.2022.113762. Online ahead of print.ABSTRACTCurrent targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage of patients responding to these treatments. This situation has prompted us to investigate the anticancer potential of the Origanum majorana Essential Oil (OMEO). In this pre-clinical study and using two major human NSCLC, namely A549 and LNM35, we demonstrated that OMEO significantly decreases the viability of these cells and the growth of their pre-formed col...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Kholoud Arafat Shahrazad Sulaiman Aya Mudhafar Al-Azawi Javed Yasin Subi Sugathan Abderrahim Nemmar Sherif Karam Samir Attoub Source Type: research
Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo
Biomed Pharmacother. 2022 Sep 28;155:113762. doi: 10.1016/j.biopha.2022.113762. Online ahead of print.ABSTRACTCurrent targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage of patients responding to these treatments. This situation has prompted us to investigate the anticancer potential of the Origanum majorana Essential Oil (OMEO). In this pre-clinical study and using two major human NSCLC, namely A549 and LNM35, we demonstrated that OMEO significantly decreases the viability of these cells and the growth of their pre-formed col...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Kholoud Arafat Shahrazad Sulaiman Aya Mudhafar Al-Azawi Javed Yasin Subi Sugathan Abderrahim Nemmar Sherif Karam Samir Attoub Source Type: research
Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo
Biomed Pharmacother. 2022 Sep 28;155:113762. doi: 10.1016/j.biopha.2022.113762. Online ahead of print.ABSTRACTCurrent targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage of patients responding to these treatments. This situation has prompted us to investigate the anticancer potential of the Origanum majorana Essential Oil (OMEO). In this pre-clinical study and using two major human NSCLC, namely A549 and LNM35, we demonstrated that OMEO significantly decreases the viability of these cells and the growth of their pre-formed col...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 1, 2022 Category: Drugs & Pharmacology Authors: Kholoud Arafat Shahrazad Sulaiman Aya Mudhafar Al-Azawi Javed Yasin Subi Sugathan Abderrahim Nemmar Sherif Karam Samir Attoub Source Type: research
