HPLC-DAD analysis of arbutin produced from hydroquinone in a biotransformation process in Origanum majorana L. shoot culture
Publication date: Available online 10 February 2017 Source:Phytochemistry Letters Author(s): Ewa Skrzypczak-Pietraszek, Inga Kwiecień, Agnieszka Gołdyn, Jacek Pietraszek The hydroquinone glucoside arbutin is a plant derived compound medically applied due to its uroantiseptic activity. It also has skin whitening properties and thus is widely used in dermatology and cosmetology. Origanum majorana L. (Lamiaceae) is known to produce arbutin, however the content of the compound in cultivated plants is very variable and low. Since plant cell and tissue cultures are capable to perform specific biotransformation reactions ...
Source: Phytochemistry Letters - February 9, 2017 Category: Chemistry Source Type: research

Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities
This article summarizes comprehensive information concerning traditional uses, phytochemistry, and pharmacological activities of sweet marjoram. (Source: Complementary Health Practice Review)
Source: Complementary Health Practice Review - December 4, 2016 Category: Complementary Medicine Authors: Bina, F., Rahimi, R. Tags: Topical Review Articles Source Type: research

Origanum majorana Essential Oil Lacks Mutagenic Activity in the Salmonella/Microsome and Micronucleus Assays.
Authors: Dantas AD, Klein-Júnior LC, Machado MS, Guecheva TN, Dos Santos LD, Zanette RA, de Mello FB, Pêgas Henriques JA, de Mello JR Abstract The present study aimed to investigate the in vitro mutagenic activity of Origanum majorana essential oil. The most abundant compounds identified by GC-MS were γ-terpinene (25.73%), α-terpinene (17.35%), terpinen-4-ol (17.24%), and sabinene (10.8%). Mutagenicity was evaluated by the Salmonella/microsome test using the preincubation procedure on TA98, TA97a, TA100, TA102, and TA1535 Salmonella typhimurium strains, in the absence or in the presence of metabolic ac...
Source: The Scientific World Journal - November 30, 2016 Category: Science Tags: ScientificWorldJournal Source Type: research

Pleasantness, familiarity, and identification of spice odors are interrelated and enhanced by consumption of herbs and food neophilia.
Abstract The primary dimension of odor is pleasantness, which is associated with a multitude of factors. We investigated how the pleasantness, familiarity, and identification of spice odors were associated with each other and with the use of the respective spice, overall use of herbs, and level of food neophobia. A total of 126 adults (93 women, 33 men; age 25-61 years, mean 39 years) rated the odors from 12 spices (oregano, anise, rosemary, mint, caraway, sage, thyme, cinnamon, fennel, marjoram, garlic, and clove) for pleasantness and familiarity, and completed a multiple-choice odor identification. Data ...
Source: Appetite - November 20, 2016 Category: Nutrition Authors: Knaapila A, Laaksonen O, Virtanen M, Yang B, Lagström H, Sandell M Tags: Appetite Source Type: research

Genotoxic studies of selected plant oil extracts on Rhyzopertha dominica (Coleoptera: Bostrichidae)
This study was conducted to compare the genotoxic effects of various concentrations of plant oils from Eruca sativa (Brassicaceae), Zingiber officinale (Zingiberaceae) and Origanum majorana (Lamiaceae) to the conventional organophosphate insecticide (Chlorpyrifos) against Rhyzopertha dominica Fabricius. The R. dominica population was reared for several generations without exposure to any insecticide. Wheat grains were sterilized at 55°C for 6h in order to eliminate any hidden infestation, treated with serial dilutions of Chlorpyrifos and plant oil extracts, and subsequently fed to R. dominica for 1, 2, 3, 6 and 8 days. Th...
Source: Journal of Taibah University for Science - November 18, 2016 Category: Science Source Type: research

Corrigendum to “LPS-induced oxidative inflammation and hyperlipidemia in male rats: The protective role of Origanum majorana extract” [Beni-Suef Univ J Basic Appl Sci 4 (4) (2015) 291–298]
Publication date: Available online 15 November 2016 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Mayssaa M. Wahby, Galila Yacout, Kamal Kandeel, Doaa Awad (Source: Beni Suef University Journal of Basic and Applied Sciences)
Source: Beni Suef University Journal of Basic and Applied Sciences - November 15, 2016 Category: Science Source Type: research

A role for red cell clearance in antibody ‐mediated inhibition of erythrocyte alloimmunization?
Antibodies targeting erythrocytes can induce antibody‐mediated inhibition of erythrocyte alloimmunization, and anti‐D has been extremely successful in preventing haemolytic disease of the foetus and newborn (HDFN). It is desirable to replace the current donor‐derived anti‐D with a monoclonal antibody; however, the exact mechanism of IgG‐mediated suppression of red blood cell immune responses remains unclear. It has been proposed that the ability of anti‐D to prevent HDFN is due to IgG interactions with Fc receptors on phagocytic cells leading to rapid clearance of RhD+ red cells. Several monoclonal anti‐D alt...
Source: ISBT Science Series - November 10, 2016 Category: Hematology Authors: D. Marjoram, Y. Cruz ‐Leal, L. Bernardo, A. H. Lazarus Tags: Congress Review Source Type: research

Genotoxic Studies of Some Plant Oil Extracts on Rhyzopertha dominica (Coleoptera: Bostrichidae)
This study was carried out to clarify the genotoxic effects of different concentrations of plant oils of Eruca sativa (Brassicaceae), Zingiber officinale (Zingiberaceae) and Origanum majorana (Lamiaceae) against the conventional organophosphate insecticide (Chlorpyrifos) as synthetic insecticide against Rhyzopertha dominica Fabricius. The R. dominica population was reared for several generations without exposure to any insecticide. Wheat grains were sterilized at a temperature of 55°C for 6hours in order to eliminate any hidden infestation then treated with serial dilutions of Chlorpyrifos and plant oil extracts and given...
Source: Journal of Taibah University for Science - October 11, 2016 Category: Science Source Type: research

The antiproliferative effect of Origanum majorana on human hepatocarcinoma cell line: suppression of NF- κB.
This study aimed to investigate the antiproliferative effect of aqueous and ethanol extracts of Origanum majorana leaf on human hepatocellular carcinoma (HepG2) cell line through incubation of various concentrations of origanum majorana extracts with HepG2 and at different time intervals. The effects of aqueous and ethanol extracts of O. majorana L. on HepG2 cell viability, nuclear factor kappa B (NF-kB) gene expression were examined. The results of the cell viability assays showed that aqueous and ethanol extracts exhibited a highly significant inhibitory effect on HepG2 cell proliferation which was evidenced by a reducti...
Source: Cellular and Molecular Biology - September 10, 2016 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

Anti-listerial effect of selected essential oils and thymol.
Abstract The anti-listerial effect of marjoram, thyme essential oils (EOs) and thymol on Listeria monocytogenes inoculated chicken breast fillets was investigated. Before inoculation the fillets were pretreated by washing or not under running tap water. Inoculated samples were kept at 6 °C for 24 h to allow the growth of L. monocytogenes. After this, the fillets were put in marinating solutions containing salt (5%) and EOs or thymol in MIC/2 concentration established in vitro. Total germ count (TGC) and L. monocytogenes count was monitored on the meat surface and in the marinating solutions following 24 a...
Source: Acta Biologica Hungarica - August 31, 2016 Category: Biology Authors: Kerekes EB, Vidács A, Török JJ, Gömöri C, Petkovits T, Chandrasekaran M, Kadaikunnan S, Alharbi NS, Vágvölgyi C, Krisch J Tags: Acta Biol Hung Source Type: research

Antibody-mediated immune suppression is improved when blends of anti-RBC monoclonal antibodies are used in mice
In conclusion, these data show that polyclonal antibodies are superior to monoclonal antibodies at suppressing the immune response to the HOD cells, a feature that can be completely recapitulated using monoclonal antibodies to different epitopes. (Source: Blood)
Source: Blood - August 24, 2016 Category: Hematology Authors: Bernardo, L., Amash, A., Marjoram, D., Lazarus, A. H. Tags: Immunobiology, Transfusion Medicine, Brief Reports Source Type: research

External Nursing Applications in the Supportive Management of Prolonged Postoperative Ileus: Description of Interventions and Case Report
We describe 3 typical techniques: Oxalis tincture compresses, Thuja/Argentum ointment compresses, and massage with “Wala Melissenöl” (containing Melissa officinalis, Carvum cari, Foeniculum amari, and Origanum majorana). A 61-year-old man with chronic pain from adhesions after multiple abdominal surgical procedures developed a prolonged postoperative ileus after an elective ileostomy reversal. Following slow recovery during the first postoperative days, he began vomiting. A nasogastric tube was inserted, and daily Oxalis tincture compresses and massage with “Wala Melissenöl” and Thuja/Argentum ointment compresses...
Source: Holistic Nursing Practice - June 18, 2016 Category: Nursing Tags: Features Source Type: research

Effect of Arbuscular Mycorrhizal Fungi on the Growth and Polyphenol Profile of Marjoram, Lemon Balm, and Marigold
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.6b00408 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - May 3, 2016 Category: Food Science Authors: Rita Engel, Krisztina Szabó, László Abrankó, Kata Rendes, Anna Füzy and Tünde Takács Source Type: research

Essential oils from Taiwan: Chemical composition and antibacterial activity against Escherichia coli
Publication date: Available online 11 April 2016 Source:Journal of Food and Drug Analysis Author(s): Po-Chen Lin, Jason Jwo Lee, I-Jy Chang The chemical compositions of seven essential oils from Taiwan were analyzed by gas chromatography-mass spectrometry. The eluates were identified by matching the mass fragment patents to the NIST 08 database. The quantitative analysis showed that the major components of lemon verbena are geranial (26.9%) and neral (23.1%); those of sweet marjoram are γ-terpinene (18.5%), thymol methyl ether (15.5%), and terpinen-4-ol (12.0%); those of clove basil are eugenol (73.6%), and β-(...
Source: Journal of Food and Drug Analysis - April 11, 2016 Category: Food Science Source Type: research

Chemical composition and in vitro evaluation of antioxidant, antimicrobial, cytotoxicity and anti-acetylcholinesterase properties of Tunisian Origanum majorana L. essential oil
This study investigated the chemical composition and evaluated the antioxidant, antimicrobial, cytotoxic and anti-acetylcholinesterase properties of Tunisian Origanum majorana essential oil. The findings showed that the oil exhibited high activity, particularly in terms of reducing power and β-Carotene bleaching, inducing higher IC50 values than BHT. The oil showed an important antimicrobial activity against 25 bacterial and fungal strains. In fact, the IZ, MIC and MBC values recorded for the bacterial strains were in the range of 8 ± 0–18.33 ± 0.57 mm, 0.097–3.125 and 0.39–6.25 mg/mL, respectively. The IZ, ...
Source: Microbial Pathogenesis - March 30, 2016 Category: Infectious Diseases Source Type: research