Editorial Board
Publication date: January 2020Source: Journal of Food and Drug Analysis, Volume 28, Issue 1Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - December 27, 2019 Category: Food Science Source Type: research
Instructions to Authors
Publication date: January 2020Source: Journal of Food and Drug Analysis, Volume 28, Issue 1Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - December 27, 2019 Category: Food Science Source Type: research
Checklist
Publication date: January 2020Source: Journal of Food and Drug Analysis, Volume 28, Issue 1Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - December 27, 2019 Category: Food Science Source Type: research
Authorship & Conflicts of Interest Statement
Publication date: January 2020Source: Journal of Food and Drug Analysis, Volume 28, Issue 1Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - December 27, 2019 Category: Food Science Source Type: research
Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis
In this study, we developed an LC/MS/MS multiple reaction monitoring (MRM) mode method to identify and quantify these metabolites formed from the metabolism of senecionine, a carcinogenic PA, by mouse, rat, and human liver microsomes, and primary rat hepatocytes. Together with the chemically prepared standards of these metabolites, this represents an accurate and convenient LC/MS/MS analytical method for quantifying these five reactive pyrrolic metabolites in biological systems. (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - December 14, 2019 Category: Food Science Source Type: research
Healthy expectations of high hydrostatic pressure treatment in food processing industry
This study examines the current progress of research on the use of HPP in the development of health foods. Through HPP, the nutritional value of food products can be enhanced or retained, including promotes the biosynthesis of γ-aminobutyric acid (GABA) in the food materials, retains immunoglobulin components in dairy products, increases resistant starch content in cereals, and reduces the glycemic index of fruit and vegetable products, which facilitates better control of blood glucose levels and decreases calorie intake. HPP can also be utilized as a hurdle technology in combination with existing processing technologies ...
Source: Journal of Food and Drug Analysis - November 30, 2019 Category: Food Science Source Type: research
Gas chromatography-mass spectrometry-based analytical strategies for fatty acid analysis in biological samples
Publication date: Available online 27 November 2019Source: Journal of Food and Drug AnalysisAuthor(s): Huai-Hsuan Chiu, Ching-Hua KuoAbstractFatty acids play critical roles in biological systems. Imbalances in fatty acids are related to a variety of diseases, which makes the measurement of fatty acids in biological samples important. Many analytical strategies have been developed to investigate fatty acids in various biological samples. Due to the structural diversity of fatty acids, many factors need to be considered when developing analytical methods including extraction methods, derivatization methods, column selections...
Source: Journal of Food and Drug Analysis - November 28, 2019 Category: Food Science Source Type: research
The matrix of SDS integrated with linear hydrophilic polymer for resolution of high- and low-molecular weight hyaluronic acids in MEKC
In this study, a capillary electrophoresis strategy was developed for resolution of different molecular-weight HA without enzymatic digestion. Here, hyaluronic acid mixtures with low molecular weight (380 kD; LHA) and high molecular weight (2180 kD; HHA) were successfully resolved by the SDS integrated with low molecular-weight polymer in capillary electrophoresis. By optimizing experimental conditions, the separation of LHA and HHA was completed within 14 min. The optimal conditions were as follows: the running buffer was 25 mM borate buffer (pH 9.75) containing 30 mM SDS and 10% polyethylene glycol (MW: 8000); applied...
Source: Journal of Food and Drug Analysis - November 28, 2019 Category: Food Science Source Type: research
In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland
Publication date: Available online 27 November 2019Source: Journal of Food and Drug AnalysisAuthor(s): Chien-Min Lin, Yi-Tzu Lin, Tai-Lin Lee, Zuha Imtiyaz, Wen-Chi Hou, Mei-Hsien LeeAbstractThe incidence of neurodegeneration leading to the conditions such as Alzheimer's and Parkinson's diseases are on the increase, they require the approaches that focus on protection prevention rather than treatment. Plants are rich sources of many compounds which possess medicinal properties. We sought to investigate the neuroprotective effects of Uncaria hirsuta and its compounds on d-galactose-induced stress in BALB/c mice as well as 6...
Source: Journal of Food and Drug Analysis - November 28, 2019 Category: Food Science Source Type: research
Bioactive peptides attenuate cardiac hypertrophy and fibrosis in spontaneously hypertensive rat hearts
In this study we aim to investigate the beneficial and synergistic effects of pure peptide amino acid sequences (DIKTNKPVIF (DI) and IF) from APPH supplement in the regulation of cardiac hypertrophy and fibrosis on spontaneously hypertensive rats (SHR). We examined hematoxylin and eosin staining, Masson's trichrome staining, echocardiographic parameters, serum parameters, hypertrophy, inflammation and fibrotic marker expression to demonstrate efficacy of bioactive peptides in a SHR model. There was a significant upregulation between SHR and bioactive peptides treated groups in left heart weight (LHW), LHW/WHW, LHW/Tibia, L...
Source: Journal of Food and Drug Analysis - November 28, 2019 Category: Food Science Source Type: research
Recent advances in cancer chemoprevention with phytochemicals
Publication date: Available online 25 November 2019Source: Journal of Food and Drug AnalysisAuthor(s): Yen-Chun Koh, Chi-Tang Ho, Min-Hsiung PanAbstractOver the past few decades, phytochemicals widely present in edible plants have exhibited compelling positive biological impact on human health, including treating some cancers. In some cases, metabolites and artificially modified products of these natural compounds have shown better chemopreventive effects than their natural counterparts. Along with direct chemopreventive strategies using phytochemicals to treat cancer by leading to cell cycle arrest, autophagy and apoptosi...
Source: Journal of Food and Drug Analysis - November 27, 2019 Category: Food Science Source Type: research
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models
In this study, we investigated a Chinese medicine (CM) formulation named NeuroDefend (ND), for reducing amyloid β (Aβ) and tau pathology in transgenic AD mice models. Regular oral administration of ND improved cognitive function and memory in 3XTg-AD and 5XFAD mice. In addition, ND reduced beta-amyloid precursor protein (APP), APP C-terminal fragments (CTF-β/α), Aβ and 4G8 positive Aβ burden in 3XTg-AD and 5XFAD mice. Furthermore, ND efficiently reduced the levels of insoluble phospho-tau protein aggregates and AT8 positive phospho tau neuron load in 3XTg-AD mice. Hence, ND could be a promising candidate for the trea...
Source: Journal of Food and Drug Analysis - October 19, 2019 Category: Food Science Source Type: research
Involvement of prohibitin 1 and prohibitin 2 upregulation in cBSA-induced podocyte cytotoxicity
Publication date: Available online 18 October 2019Source: Journal of Food and Drug AnalysisAuthor(s): Heng-Hsiung Wu, Chao-Jung Chen, Pei-Yu Lin, Yu-Huei LiuAbstractMembranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults, when not effectively treated. The aim of this study was to discover new targets for the diagnosis and treatment of MN. A reliable mouse model of MN was used by the administration of cationic bovine serum albumin (cBSA). Mice with MN exhibited proteinuria, histopathological changes, and accumulation of immune complexes in the glomerular basement membrane. Label-free proteomics ...
Source: Journal of Food and Drug Analysis - October 19, 2019 Category: Food Science Source Type: research
Alleviating chronic kidney disease progression through modulating the critical genus of gut microbiota in a cisplatin-induced Lanyu pig model
Publication date: Available online 17 October 2019Source: Journal of Food and Drug AnalysisAuthor(s): Ya-Jane Lee, Kuan-Yi Li, Pin-Jhu Wang, Hsiao-Wen Huang, Ming-Ju ChenAbstractIn the present study, we investigated the effects of Probiotic mix 1 (Pm1) with Lactobacillus plantarum subsp. plantarum, Lactobacillus paracasei subsp. paracasei, and Streptococcus salivarius subsp. thermophilus on preventing renal injury using a chronic kidney disease (CKD) minipig model previously developed in our lab using cisplatin-induced CKD in Lanyu pigs. The results indicated that the high dosage Pm1 (H.Pm1) group demonstrated lower incide...
Source: Journal of Food and Drug Analysis - October 19, 2019 Category: Food Science Source Type: research
NeuroDefend, a novel traditional Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models
In this study, we investigated a Chinese medicine (CM) formulation named NeuroDefend (ND), for reducing amyloid β (Aβ) and tau pathology in transgenic AD mice models. Regular oral administration of ND improved cognitive function and memory in 3XTg-AD and 5XFAD mice. In addition, ND reduced beta-amyloid precursor protein (APP), APP C-terminal fragments (CTF-β/α), Aβ and 4G8 positive Aβ burden in 3XTg-AD and 5XFAD mice. Furthermore, ND efficiently reduced the levels of insoluble phospho-tau protein aggregates and AT8 positive phospho tau neuron load in 3XTg-AD mice. Hence, ND could be a promising candidate for the trea...
Source: Journal of Food and Drug Analysis - October 10, 2019 Category: Food Science Source Type: research
