Bacterial surveillance of apheresis platelets in South Africa (January 2011 to December 2016)
ConclusionBacterial contamination rates, mostly due to gram ‐positive bacteria, increased since 2011. Bacterial screening must be aligned with international recommendations, and novel technologies should be explored to reduce the residual risk. (Source: ISBT Science Series)
Source: ISBT Science Series - November 28, 2018 Category: Hematology Authors: Ute Jentsch, Ronel Swanevelder Tags: Original Paper Source Type: research

Red cell transfusion thresholds in haematopoietic stem cell transplantation
Red cell transfusions are part of the routine supportive care following haematopoietic stem cell transplantation. There is increasing evidence from randomized controlled trials demonstrating that restrictive transfusion thresholds are equivalent to liberal thresholds in other patient populations. However, given the lack of patient ‐centred outcomes and the longer transfusion support required for patients with haematologic malignancies, the results of these trials may not be generalizable to haematology–oncology patients. In the recently completed multicentre TRIST trial, we randomized 300 patients requiring an auto...
Source: ISBT Science Series - November 22, 2018 Category: Hematology Authors: Alan Tinmouth, Jason Tay Tags: Congress Review Source Type: research

Magnitude and risk factors for cytomegalovirus infection among voluntary blood donors at National Blood Bank, Addis Ababa Ethiopia
BackgroundHuman cytomegalovirus (CMV) is a ubiquitous agent that commonly infects individuals from diverse geographical and socio ‐economic backgrounds. The infection is a major concern among some populations of blood transfusion recipients, especially neonates and immune‐compromised patients. Information on the burden of the infection is very scarce, and to the best of our knowledge, there is no documented evidence regard ing its distribution and risk factors among blood donors in Ethiopia. Therefore, this study assesses the magnitude and risk factors for cytomegalovirus infection among voluntary blood donors at Natio...
Source: ISBT Science Series - November 22, 2018 Category: Hematology Authors: Yeabkal Daniel Teka, Habtemariam Demoz, Fanuel Belayneh Bekele, Kassu Desta Tulu Tags: Original Paper Source Type: research

After 70 years, serological RhD determination remains a challenge: DNA to the rescue
After ABO system antigens, RhD is the most clinically significant blood group antigen. This is reflected in its high immunogenicity and potential to cause haemolytic transfusion reactions (HTR) and severe haemolytic disease of the newborn (HDN). Thus, correct determination of the RhD antigen is essential for a safe transfusion strategy and adequate indications of anti ‐D immunoglobulin prophylactic administration. The RhD determination challenge started in 1939 with a case history of fatal HDN and HTR in a mother who was transfused with her husband′s blood. Subsequent findings of an antibody reacting with 80% ABO c...
Source: ISBT Science Series - November 22, 2018 Category: Hematology Authors: Martin P ísačka Tags: Congress Review Source Type: research

Emerging infectious diseases and blood donation
Emerging infectious diseases (EIDs) require vigilance from blood banks everywhere. As EIDs spread to new areas and populations, blood banks are forced to re ‐evaluate safety measures continually. Screening, pathogen inactivation and deferral policies must be balanced against supply, safety and cost‐effectiveness. One size does not fit all, and blood banks must adjust to local needs and conditions when considering initiation or halting of screening, pathogen inactivation or deferral procedures to balance between demand/supply, safety and economy. (Source: ISBT Science Series)
Source: ISBT Science Series - November 20, 2018 Category: Hematology Authors: Bertram Kjerulff, Christian Erikstrup Tags: Congress Review Source Type: research

Towards a safe and sufficient blood supply in Sub ‐Saharan Africa
Most countries in Sub ‐Saharan Africa (SSA) are either low‐income or low‐middle income countries, that is countries whose gross national income per capita is $995 (USD) or less or $996–3895, respectively. Added to this, they have very few health care professionals specifically trained in transfusion medicine and are the countries whose populations have a high prevalence of transfusion‐transmissible agents (especially HIV, hepatitis B and malaria) and whose patients (women haemorrhaging at birth, men in motor vehicle or motorcycle accidents, children with malaria or sickle cell anaemia) are often in urgent nee...
Source: ISBT Science Series - November 12, 2018 Category: Hematology Authors: Dorothy Kyeyune ‐Byabazaire, Heather A. Hume Tags: Congress Review Source Type: research

Nature and causes of errors in the blood transfusion chain – a step towards patient safety
ConclusionThe data obtained through this study highlight the various critical steps where errors can occur in the long chain of blood transfusion. (Source: ISBT Science Series)
Source: ISBT Science Series - November 12, 2018 Category: Hematology Authors: Gurpreet Kaur, Gagandeep Kaur, Paramjit Kaur Tags: Original Paper Source Type: research

Blood donor behaviour, motivations and the need for a systematic cross ‐cultural perspective: the example of moral outrage and health‐ and non‐health‐based philanthropy across seven countries
ConclusionsWe contend that these findings provide proof of principle why a cross ‐cultural perspective on blood donor behaviour is needed. (Source: ISBT Science Series)
Source: ISBT Science Series - November 12, 2018 Category: Hematology Authors: Eamonn Ferguson, Laszlo Dorner, Christopher R. France, Janis L. France, Barbara Masser, Michael Lam, Elena Marta, Sara Alfieri, Eva ‐Maria Merz, Byron Adams, Elisabeth Huis in ’t Veld, Josianne Scerri Tags: Original Paper Source Type: research

Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex
This study investigated the impact of donor age and sex on RCC characteristics and the effect of RCC supernatants on the vascular endothelium and monocytes.Materials and methodsRCC units selected from four donor groups based on donor age and sex (male  ≤ 30‐years old (yo), male ≥ 60‐yo, female ≤ 30‐yo and female ≥ 60‐yo) were stored at 1–6°C and tested on day 7, 21 and 42. RCC supernatants were analysed for the number, concentration and size of extracellular vesicles (EVs). Human vein endothelial cells (HUVECs) monolaye rs were incubated with RCC superna...
Source: ISBT Science Series - November 12, 2018 Category: Hematology Authors: Betty J. Kipkeu, Ruqayyah Almizraq, Donald R. Branch, Jason P. Acker, Jelena L. Holovati Tags: Original Paper Source Type: research

Drug ‐induced immune haemolytic anaemias
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - November 5, 2018 Category: Hematology Authors: Donald R. Branch Source Type: research

Platelets from donors who use non ‐steroidal anti‐inflammatory drugs are functional when stored under blood bank conditions
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - November 5, 2018 Category: Hematology Authors: Ido J. Bontekoe, St éphanie A. Groot, Pieter F. Meer, Dirk Korte Source Type: research

Building a blood system: the view from Saudi Arabia
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 31, 2018 Category: Hematology Authors: Maha A. Badawi Source Type: research

When things go badly – Managing quality problems and complaints in transfusion medicine
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 25, 2018 Category: Hematology Authors: Tomislav Vuk Source Type: research

The practice of transfusion and fluid bolus therapy in neonates
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 25, 2018 Category: Hematology Authors: Amy K. Keir, Simon J. Stanworth Source Type: research

Disaster planning: the role of the transfusion practitioner
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 19, 2018 Category: Hematology Authors: Rozemarijn Deelen, Els Costermans, Rachel Moss, Christine Akers Source Type: research

Demographic and health profile of older Australian blood donors: results from the Extended Donor Vigilance data linkage study (EDV:Link)
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 17, 2018 Category: Hematology Authors: Carley N. Gemelli, Amanda Thijsen, Surendra Karki, Tanya E. Davison, David O. Irving, Stephen T. Wright Source Type: research

The relation between blood donor recruitment and donor diversity and loyalty in the Netherlands
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 15, 2018 Category: Hematology Authors: Tjeerd W. Piersma, Elisabeth F. Klinkenberg Source Type: research

Establishing performance management objectives and measurements of red blood cell inventory planning in a large tertiary care hospital in British Columbia, Canada
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 15, 2018 Category: Hematology Authors: David Pi, Andrew W. Shih, Lawrence Sham, David Zamar, Kristine Roland, Monika Hudoba Source Type: research

Emotions experienced when receiving a temporary deferral: perspectives from staff and donors
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 15, 2018 Category: Hematology Authors: Carley N. Gemelli, Amanda Thijsen, Nina Van Dyke, Barbara M. Masser, Tanya E. Davison Source Type: research

Stem cell mismarketing: Implications for the transfusion community
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 8, 2018 Category: Hematology Authors: Douglas Sipp Source Type: research

Comparative blood donation knowledge attitudes and practice surveys from two multi ‐ethnic communities
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 8, 2018 Category: Hematology Authors: Kenneth S. Charles, Sudha Bhagwansingh Source Type: research

Patient blood management
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 8, 2018 Category: Hematology Authors: Patrick Meybohm, Suma Choorapoikayil, Anahita Regaei, Mona Jung ‐König, Kai Zacharowski Source Type: research

Can we do better? Bridging the research to practice gap in patient blood management –optimizing ‘audit & feedback ’ and the challenges of undertaking a national cluster‐randomized controlled trial
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - October 1, 2018 Category: Hematology Authors: Simon J Stanworth, Fabiana Lorencatto, Natalie Gould, John Grant ‐Casey, Alison Deary, Suzanne Hartley, Stephen McIntyre, Lauren Moreau, Thomas Morris, Riya Patel, Isabelle Smith, James Smith, Amanda Farrin, Robbie Foy, Jill Francis, On be Source Type: research

Kidd blood group system: outwardly simple with hidden complexity
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 28, 2018 Category: Hematology Authors: Janis R. Hamilton Source Type: research

Microbial safety of cellular therapeutics —lessons from over ten years’ experience in microbial safety of platelet concentrates
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 20, 2018 Category: Hematology Authors: Melanie St örmer , Erica M. Wood , Birgit Gathof Source Type: research

Estimate of future blood demand in Japan and the number of blood donations required
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 14, 2018 Category: Hematology Authors: Chiharu Kano , Minoko Takanashi , Asami Suzuki , Kazuo Kawahara , Koichi Chiba , Hideo Nakanishi , Junki Takamatsu , Akiko Kitai , Koki Takahashi Source Type: research

Immune role of platelets in malaria
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 12, 2018 Category: Hematology Authors: Brendan J. McMorran Source Type: research

Questioning the benefit of restrictive transfusion practice in older adults
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 7, 2018 Category: Hematology Authors: Geoff I. Simon , Alison Craswell , Ogilvie Thom , Yoke Lin Fung Source Type: research

Adherence to clinical guidelines for use of blood components at a tertiary hospital in Ghana
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 7, 2018 Category: Hematology Authors: Ankush Dhariwal , Emmanuel Allotey , Amelia Fisher , Imelda Bates Source Type: research

Transfusion emergency preparedness for mass casualty events
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 5, 2018 Category: Hematology Authors: Heidi Doughty , Richard Rackham Source Type: research

Transfusion ‐associated circulatory overload (TACO): Time to shed light on the pathophysiology
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 5, 2018 Category: Hematology Authors: John W. Semple , Johan Rebetz , Rick Kapur Source Type: research

NONE TOO S.M.A.LL: the global challenge of severe malarial anaemia and its transfusion support
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 5, 2018 Category: Hematology Authors: Christine Cserti ‐Gazdewich Source Type: research

Moving from a permanent to a 5 year deferral for donors with cured cancer results in a substantial reduction in deferral rates
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - September 5, 2018 Category: Hematology Authors: Mindy Goldman , Qi ‐Long Yi , Sheila F. O'Brien Source Type: research

Getting comfortable with RH blood group system terminologies and databases
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - August 22, 2018 Category: Hematology Authors: F. F. Wagner Source Type: research

Issue Information
ISBT Science Series,Volume 13, Issue 3, Page 195-196, August 2018. (Source: ISBT Science Series)
Source: ISBT Science Series - August 21, 2018 Category: Hematology Source Type: research

First detection of human T ‐lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - August 2, 2018 Category: Hematology Authors: Adjile Edjide Roukiyath Amoussa , Simone Kashima , Didier Djobessi , Fernanda Khouri Barreto , Denise Davou , Andre Bigot , Ludovic Anani , Jose Louren ço , Marta Giovanetti , Ester Sabino , Mohamed Cherif Rahimy , Luiz Carlos Juni Source Type: research

Vasovagal reaction in blood donors: prediction and its impact on donor return
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - August 1, 2018 Category: Hematology Authors: Hoi ‐kei Wong , Cherry Chui‐yee Chu , Ching‐wa Lau , Jennifer Ngar‐sze Leung , Idy Yik‐mun Lee , Cheuk‐kwong Lee Source Type: research

Prevalence of Zika Virus (Zikv) in blood donors from a hemotherapy service of the southern region of Brazil
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - June 8, 2018 Category: Hematology Authors: C. F. Diefenbach , S. N. Slavov , S. Kashima , A. R. Ferreira , M. R. Hespanhol , B. S. Bandeira , B. S. Vizzotto , L. M. F. Krause , J. S. Martins Source Type: research

Passenger lymphocyte syndrome due to anti ‐B and anti‐Jka following combined intestinal and renal transplantation
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - June 4, 2018 Category: Hematology Authors: C. C. Chua , H. Lim , A. Testro , F. S. Hong Source Type: research

Implementing a patient blood management programme in Brazil: challenges and implications for developing countries
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - May 24, 2018 Category: Hematology Authors: B. D. Benites , M. Addas ‐Carvalho Source Type: research

Issue Information
ISBT Science Series,Volume 13, Issue 2, Page 121-122, May 2018. (Source: ISBT Science Series)
Source: ISBT Science Series - May 18, 2018 Category: Hematology Source Type: research

Knowledge, attitudes and risk perception surrounding blood transfusion in Trinidad and Tobago
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - May 15, 2018 Category: Hematology Authors: K. S. Charles , K. S. Metivier , S. Sammy , M. Labban , M. Rudder , S. Singh , A. Reginald , S. Ramoutar , G. Legall , S. Pooransingh , A. D. Chantry Source Type: research

What are the special issues for young donors?
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - April 15, 2018 Category: Hematology Authors: H. H. Tan , R. M. Alcantara Source Type: research

Update on epidemiology of hepatitis B virus among blood donors in China
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - April 14, 2018 Category: Hematology Authors: J. Huang , Q. You , D. Song , X. Rong , C. Li , Y. Fu Source Type: research

Experience of haemovigilance in Japan
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - April 7, 2018 Category: Hematology Authors: M. Satake Source Type: research

Cell sources for large ‐scale manufacture of red blood cells
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - April 6, 2018 Category: Hematology Authors: S. Kim , E. J. Baek Source Type: research

Trends in hepatitis B and hepatitis C seroprevalence among blood donors – Haiti, 2005‐2014
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - March 23, 2018 Category: Hematology Source Type: research

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ISBT Science Series, Ahead of Print. (Source: ISBT Science Series)
Source: ISBT Science Series - March 23, 2018 Category: Hematology Source Type: research

Haemovigilance in China: experiences, challenges and strategies
ISBT Science Series, EarlyView. (Source: ISBT Science Series)
Source: ISBT Science Series - March 8, 2018 Category: Hematology Source Type: research

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ISBT Science Series, Ahead of Print. (Source: ISBT Science Series)
Source: ISBT Science Series - March 8, 2018 Category: Hematology Source Type: research