Oregano and/or Marjoram: Traditional Oil Production and Ethnomedical Utilization of Origanum Species in southern Turkey
In this study, traditional oil production and ethnomedical utilization of plant products are presented from the Antalya region in southern Turkey. The native people harvest species from wild populations and air-dry them under the sun. They consume and sell mainly air-dried Origanum onites (Turkish oregano) leaves. They obtain essential oil traditionally by steam distillation from Origanum majorana (white marjoram) due to its high oil yield. The native people use dried plant material and essential oil to cure various diseases such as cough, chronic cold, wounds, gastrointestinal disorders and skin problems in humans as well...
Source: Journal of Herbal Medicine - January 11, 2019 Category: Complementary Medicine Source Type: research
Marjoram Extract Down-regulates the Expression of Pasteurella multocida Adhesion, Colonization and Toxin genes: a Potential Mechanism for its Antimicrobial activity
This study provides an in vitro research framework to investigate the antibacterial activities of 5 herbal (marjoram, garlic, onion, cinnamon and black seed) extracts against 16 multidrug-resistant and virulent P. multocida serogroup A isolates recovered from dead and clinically diseased rabbits. Pathogenicity of the screened isolates was further proven experimentally and was verified by PCR analyses of 5 randomly selected virulence genes encoding attachment and colonization proteins (ptfA, pfhA, and omp87), sialidases (nanB) and dermonecrotoxin (toxA). A total of 12 P. multocida isolates were highly pathogenic with the po...
Source: Comparative Immunology, Microbiology and Infectious Diseases - December 5, 2018 Category: Infectious Diseases Source Type: research
Voltammetric determination of carvacrol on Boron Doped Diamond Electrode.
Abstract
A simple, sensitive and rapid method of carvacrol determination using Boron Doped Diamond Electrode (BDDE) and Differential Pulse Voltammetry (DPV) was described. To the best of our knowledge, this is the first presentation of electrochemical method to determine this compound on BDDE. In presented conditions, carvacrol undergoes irreversible one-electron oxidation controlled by diffusion. The measurement conditions and composition of supporting electrolyte were developed and optimized. Optimal measurement parameters were achieved using 0.1 molL-1 acetate buffer pH 6.0 as supporting electrolyte. Th...
Source: Analytica Chimica Acta - November 22, 2018 Category: Chemistry Authors: Kowalcze M, Jakubowska M Tags: Anal Chim Acta Source Type: research
Carvacrol induces mitochondria ‐mediated apoptosis via disruption of calcium homeostasis in human choriocarcinoma cells
In this study, we demonstrated that carvacrol exertes antiproliferative effects through suppression of phosphoinositide 3 ‐kinase–protein kinase B and mitogen‐activated protein kinase signaling, generating oxidative stress and altering calcium homeostasis mediated by mitochondrial dysfunction in human choriocarcinoma JAR and JEG3 cells. Therefore, carvacrol has a possibility as a novel therapeutic agent or supple ment for the treatment of choriocarcinoma patients. Carvacrol is a monoterpenoid phenol present in the oils of various plants includingOriganum vulgare (oregano) orOriganum majorana (marjoram). For a long ti...
Source: Journal of Cellular Physiology - November 20, 2018 Category: Cytology Authors: Whasun Lim,
Jiyeon Ham,
Fuller W. Bazer,
Gwonhwa Song Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Myorelaxant Activity of essential oil from Origanum majorana L. on rat and rabbit
Conclusionthe present result indicates that essential oil of Origanum majorana L. exhibit an effect on intestinal relaxation in vitro. This effect further validates the traditional use of Origanum majorana L. to treat infantile colic and abdominal discomfort.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - November 3, 2018 Category: Drugs & Pharmacology Source Type: research
Myorelaxant Activity of essential oil from Origanum majorana L on rat and rabbit
Conclusionthe present result indicates that essential oil of Origanum majorana L. exhibit an effect on intestinal relaxation in vitro. This effect further validates the traditional use of Origanum majorana L. to treat infantile colic and abdominal discomfort.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 23, 2018 Category: Drugs & Pharmacology Source Type: research
Origanum majorana L. extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea
Conclusionthe present results indicate that aqueous extract of Origanum majorana L. exhibit positive cooperative effects on the main mechanisms that are involved in acute infectious diarrhea.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - September 22, 2018 Category: Drugs & Pharmacology Source Type: research
Cytotoxicity of the Aqueous Extract and Organic Fractions from Origanum majorana on Human Breast Cell Line MDA-MB-231 and Human Colon Cell Line HT-29.
Authors: Makrane H, El Messaoudi M, Melhaoui A, El Mzibri M, Benbacer L, Aziz M
Abstract
The toxicity of the aqueous extract of Origanum majorana was tested (5 and 10 g/kg) in albino mice. No symptoms of toxicity or mortality were observed. The mice survived being active and healthy during all 14 days of observation. In addition, the weight measurement of the left and right kidneys, heart, and liver shows no significant difference between the control, 5 g/kg, and 10 g/kg. All extracts (aqueous, petroleum ether, dichloromethane, ethyl acetate, methanolic, and depleted aqueous extracts) of Origanum maj...
Source: Advances in Pharmacological Sciences - September 15, 2018 Category: Drugs & Pharmacology Tags: Adv Pharmacol Sci Source Type: research
Origanum majorana L extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea
Conclusionthe present results indicate that aqueous extract of Origanum majorana L. exhibit positive cooperative effects on the main mechanisms that are involved in acute infectious diarrhea.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - September 12, 2018 Category: Drugs & Pharmacology Source Type: research
Origanum majorana L extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea
Conclusionthe present results indicate that aqueous extract of Origanum majorana L. exhibit positive cooperative effects on the main mechanisms that are involved in acute infectious diarrhea.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - September 9, 2018 Category: Drugs & Pharmacology Source Type: research
The antibacterial and physiological effects of pure and nanoencapsulated Origanum majorana essential oil on fish infected with Aeromonas hydrophila
This study evaluated the antibacterial activity of Origanum majorana essential oil (EOM) and nanocapsules of this oil (NOM) in silver catfish, Rhamdia quelen, infected with Aeromonas hydrophila, and addressed their effects on silver catfish hematological and metabolic parameters. Fish were inoculated with A. hydrophila (360 μL, at a concentration of 1.5 × 109 CFU mL−1) and submitted to 1 h daily baths with EOM (0 (control), 20 or 30 μL L−1), NOM (0 (control), 5 or 10 μL L−1) or a positive control containing florfenicol (30 μL L−1) called group Maxflor® for five consecutive days. All tr...
Source: Microbial Pathogenesis - August 21, 2018 Category: Infectious Diseases Source Type: research
Chemical composition, antioxidant activity and antifungal effects of five Iranian essential oils against Candida strains isolated from urine samples
This study reported the chemical composition, antioxidant and anti-Candida activity of Origanum majorana, Artemisia dracunculus, Cymbopogon citrate, Cinnamomum verum and Caryophyllus aromaticus essential oils. Different Candida species, from urine tracts of hospitalized patients, were included to be challenged with understudied essential oils. Chemical compositions were determined using gas chromatography/mass spectroscopy (GC/MS) analysis and antioxidant activity was measured using DDPH assay. MIC of these essential oils was evaluated using broth micro-dilution test. Caryophyllus aromaticus had the highest antioxidant act...
Source: Journal of Medical Mycology - July 11, 2018 Category: Biology Source Type: research
Antimicrobial activity of five essential oils from lamiaceae against multidrug-resistant Staphylococcus aureus.
Abstract
Analysis of Lamiaceae essential oils (EOs) by GC-FID-MS revealed the presence as the major constituents of linalool (16.8%), linalyl acetate (15.7%) in Lavandula angustifolia, menthol (29.0%), menthone (22.7%), menthyl acetate (19.2%) in Mentha x piperita, terpinen-4-ol (27.1%), (E)-sabinene hydrate (12.1%), γ-terpinene (10.0%) in Origanum majorana, α-thujone (19.5%), camphor (19.0%), viridiflorol (13.5%) in Salvia officinalis, thymol (61.9%), p-cymene (10.0%), γ-terpinene (10.0%) in Thymus vulgaris. Based on the MIC and MBC values (0.09-0.78 mg/mL) and ratio MBC/MIC showed that EO from T. vul...
Source: Natural Product Research - June 11, 2018 Category: Biochemistry Authors: Kot B, Wierzchowska K, Piechota M, Czerniewicz P, Chrzanowski G Tags: Nat Prod Res Source Type: research
Chemical analysis of aqueous extracts of Origanum majorana and Foeniculum vulgare and their efficacy on Blastocystis spp. cysts
Conclusion O. majorana and F. vulgare AEs showed dose and time dependent anti-Blastocystis activity. Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - April 10, 2018 Category: Drugs & Pharmacology Source Type: research
