Editorial Board
Publication date: September 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 3Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 23, 2019 Category: Biology Source Type: research

Genotyping of Candida albicans isolates from oropharyngeal candidiasis in head and neck cancer patients in Iran: Molecular epidemiology and SAP2 gene expression
ConclusionWe found few genetically-related as well as identical isolates among the 32 Candida strains which indicated low cross-contaminations among the patients. There was no relationship between C. albicans MLST profiles and their geographic distribution, cancer type and SAP2 gene expression. This lack of correlation was possibly due to the small understudy population; hence, finding more relevance requires studies with a higher number of samples. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 19, 2019 Category: Biology Source Type: research

African Histoplasmosis in a Guinea Bissau Patient with HIV-2: Case Report and Review
We present the case of a 30-year-old Bissau-Guinean man with HIV-2 infection known for 16 years, irregularly treated, admitted with two weeks of fever, diarrhoea and cutaneous lesions. Examination revealed multiple subcutaneous nodes, Molluscum contagiosum-like lesions, generalized lymphadenopathy and painful palpation of the left iliac fossa. Laboratory tests showed severe nonhaemolytic anaemia and CD4+ count of 9/mm3, with normal creatinine and hepatic enzymes. Chest roentgenogram was unremarkable and a research for Mycobacterium tuberculosis by GeneXpert® was negative. Nonetheless, given the lack of further diagnost...
Source: Journal of Medical Mycology - October 19, 2019 Category: Biology Source Type: research

Evolution of fungemia in an italian region
Publication date: Available online 15 October 2019Source: Journal de Mycologie MédicaleAuthor(s): Anna Prigitano, Caterina Cavanna, Marco Passera, Marina Gelmi, Eugenio Sala, Cristina Ossi, Anna Grancini, Maria Calabrò, Simone Bramati, Milvana Tejada, Fabiola Lallitto, Claudio Farina, Vanina. Rognoni, Maria Antonietta Fasano, Beatrice Pini, Luisa Romanò, Massimo Cogliati, Maria Carmela Esposto, Anna Maria TortoranoAbstractBackground: Fungemia represents a public health concern. Knowing aetiology and activity of the antifungals is critical for the management of bloodstream infections. Therefore, ...
Source: Journal of Medical Mycology - October 16, 2019 Category: Biology Source Type: research

Refractory sporotrichosis due to Sporothrix brasiliensis in Argentina: case report, molecular identification and in vitro susceptibility pattern to antifungal drugs
Conclusions: this study contributed to the molecular epidemiology of Sporothrix species in Argentina and the characterization of the in vitro susceptibility pattern of S. brasiliensis isolates recovered from a cat and two humans involved in this case of zoonotic and refractory sporotrichosis. Bearing in mind the concept of “one health”, the experience described in the present study highlights the need for future strategies for sporotrichosis treatment, control and prevention. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 16, 2019 Category: Biology Source Type: research

Frequency, virulence factors and antifungal susceptibility of Candida parapsilosis species complex isolated from patients with candidemia in the central region of Argentina
Publication date: Available online 15 October 2019Source: Journal de Mycologie MédicaleAuthor(s): Cecilia Vigezzi, Paula Alejandra Icely, Catiana Dudiuk, Emilse Rodríguez, María Soledad Miró, Graciela del Valle Castillo, Ana Isabel Azcurra, Claudio Abiega, Juan Pablo Caeiro, Fernando Oscar Riera, Guillermo García-Effrón, Claudia Elena SotomayorAbstractPurpose: Our objectives were to report species distribution and survival of patients with candidemia in Argentina´s central region and to establish the prevalence of C.parapsilosis sensu lato species, their virulence factors and...
Source: Journal of Medical Mycology - October 16, 2019 Category: Biology Source Type: research

Impact of Iron Chelators on Growth and Expression of Iron-Related Genes of Cryptococcus species
Conclusion: Synergistic antifungal activity of combination DFO and AMB was observed in Cryptococcus. Relatively increased CFT1 and CFT2 expression may be associated with the effect of DFO that inhibits the growth of fungi. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 13, 2019 Category: Biology Source Type: research

Page informations
Publication date: September 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 3Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 5, 2019 Category: Biology Source Type: research

CV2 / Ours de la rédaction - Editorial Board
Publication date: September 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 3Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - October 5, 2019 Category: Biology Source Type: research

Epidemiological profile of eumycetomas in Rabat, Morocco, over 40 years
The objective of our work is to establish their epidemiological, clinical and mycological profile in our Moroccan context. Therefore, we conducted a retrospective study, extending from 1975 to 2019, compiling all cases of eumycetomas that were diagnosed in the parasitology-mycology laboratory of the Ibn Sina University Hospital of Rabat. The diagnosis, based on the swabbing of exudates and eventual grains or the study of biopsies, included the direct examination of 30% KOH mounts, the realization of appositions colored by May-Grünwald-Giemsa and the incubation on 3 Sabouraud media at 27° and 37 °C. I...
Source: Journal of Medical Mycology - October 4, 2019 Category: Biology Source Type: research

A computational study targeting the mutated L321F of ERG11 gene in C. albicans, associated with fluconazole resistance with bioactive compounds from Acacia nilotica
Publication date: Available online 12 September 2019Source: Journal de Mycologie MédicaleAuthor(s): M. Sohaib Shahzan, A.S. Smiline Girija, J. Vijayashree PriyadharsiniAbstractBackgroundEmergence of fluconazole resistance mediated by L321F mutation in the ERG11 gene poses a serious impediment in the candidal treatment process. This leads to the search of novel target proteins to develop newer drugs against fluconazole resistant C. albicans. The present investigation is thus aimed to explore the inhibitory potential of bioactive compounds from A. nilotica against the wild and mutated ERG11 gene of C. a...
Source: Journal of Medical Mycology - September 28, 2019 Category: Biology Source Type: research

Epidemiological profile of eumycetomas in Rabat, Morocco, over 40 years. Profil épidémiologique des eumycétomes à Rabat, au Maroc, sur plus de 40 ans
The objective of our work is to establish their epidemiological, clinical and mycological profile in our Moroccan context. Therefore, we conducted a retrospective study, extending from 1975 to 2019, compiling all cases of eumycetomas that were diagnosed in the parasitology-mycology laboratory of the Ibn Sina University Hospital of Rabat. The diagnosis, based on the swabbing of exudates and eventual grains or the study of biopsies, included the direct examination of 30% KOH mounts, the realization of appositions colored by May-Grünwald-Giemsa and the incubation on 3 Sabouraud media at 27° and 37°C. In 44 years,...
Source: Journal of Medical Mycology - September 26, 2019 Category: Biology Source Type: research

A new mutation in the SQLE gene of Trichophyton mentagrophytes associated to terbinafine resistance in a couple with disseminated tinea corporis
We report two cases of tinea corporis resistant to systemic terbinafine in a 60-year-old man and his wife, a 51 year-old-woman. Both patients had multiple diffuse erythematous annular scaly plaques and T. mentagrophytes was isolated in culture. Systemic treatment with terbinafine in combination with topical terbinafine and then topical ketoconazole failed to improve the disease after 8 weeks. The broth microdilution tests performed to evaluate the antifungal sensitivity of the T. mentagrophytes isolate revealed a high MIC for terbinafine but a low MIC for posaconazole and itraconazole. An A1223T point mutation leading to a...
Source: Journal of Medical Mycology - September 26, 2019 Category: Biology Source Type: research

Biochemical and cellular activity of chemically synthesized elastase inhibitor (S-AFUEI) from Aspergillus fumigatus
ConclusionAs S-AFUEI strongly inhibited cytotoxicity induced by elastase in human-derived cells, it could prove beneficial for the treatment of pulmonary aspergillosis. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - September 24, 2019 Category: Biology Source Type: research

Detection of virulence factors and antifungal susceptibility of human and avian Aspergillus flavus isolates
Publication date: Available online 12 September 2019Source: Journal de Mycologie MédicaleAuthor(s): Dhoha Ghorbel, Inès Hadrich, Sourour Neji, Houaida Trabelsi, Hatem Belaaj, Hayet Sellami, Fatma Cheikhrouhou, Fattouma Makni, Ali AyadiAbstractAspergillus flavus is the second leading cause of invasive and non-invasive aspergillosis. Secretion of hydrolytic enzymes is considered as a virulence factor in this species. Our work aimed to study in vitro production of some virulence factors, to evaluate the biofilm production against human and avian A. flavus isolates and to investigate the antifungal susceptibility...
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

A computational study targeting the mutated L321F of ERG11 gene in C.albicans, associated with fluconazole resistance with bioactive compounds from Acacia nilotica
Publication date: Available online 12 September 2019Source: Journal de Mycologie MédicaleAuthor(s): Mohammed Sohaib Shahzan, A.S Smiline Girija, J Vijayashree PriyadharsiniABSTRACTBackground: Emergence of fluconazole resistance mediated by L321F mutation in the ERG11 gene poses a serious impediment in the candidal treatment process. This leads to the search of novel target proteins to develop newer drugs against fluconazole resistant C.albicans. The present investigation is thus aimed to explore the inhibitory potential of bioactive compounds from A.nilotica against the wild and mutated ERG11 gene of C.albicans.Mate...
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

Prototheca wickerhamii prepatellar bursitis in an immunocompetent woman: A case report
We report a patient who had no apparent immunodeficiency developed P. wickerhamii prepatellar bursitis following intra-bursal corticosteroid injection. Clinical manifestations could not distinguish Prototheca bursitis from septic bursitis caused by other pathogens. Bursal fluid aspiration sent for direct microscopic examination and cultures could give an early diagnosis. Systemic antifungal therapy with complete surgical excision of infected bursa provided a good outcome. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

Human infections due to Schizophyllum commune: case report and review of the literature
Publication date: Available online 12 September 2019Source: Journal de Mycologie MédicaleAuthor(s): Caterina Cavanna, Fabio Pagella, Maria Carmela Esposto, Francesca Tamarozzi, Libera Clemente, Piero Marone, Elina Matti, Fabiola LallittoAbstractSchizophyllum commune is an environmental basidiomycetous fungus, causing occasional, predominantly respiratory, infections in humans. Although S. commune is considered an emerging pathogen, some authors pointed out the possibility that recent advances in diagnostic technologies now allow a more prompt and precise identification at the species level. Here we describe the firs...
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

Amyloidosis secondary to chronic pulmonary aspergillosis: case report and a systematic review of literature
Publication date: Available online 12 September 2019Source: Journal de Mycologie MédicaleAuthor(s): Dharmesh Patel, Ritesh Agarwal, Sahajal Dhooria, Umapati Hedge, Hardik Patel, Inderpaul Singh SehgalAbstractSecondary amyloidosis results from the deposition of abnormally folded proteins in body organs due to chronic inflammatory disorders. Kidneys are the most commonly affected organ and manifest as nephrotic syndrome with or without renal failure. Chronic pulmonary aspergillosis (CPA) is a chronic infection of lung parenchyma affecting those with an underlying structural lung disease. Herein, we present a case of C...
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

Genotyping of Candida albicans isolates from oropharyngeal candidiasis in head & neck cancer patients in Iran: Molecular epidemiology and SAP2 gene expression
Conclusion: We found few genetically-related as well as identical isolates among the 32 Candida strains which indicated low cross-contaminations among the patients. There was no relationship between C. albicans MLST profiles and their geographic distribution, cancer type and SAP2 gene expression. This lack of correlation was possibly due to the small understudy population; hence, finding more relevance requires studies with a higher number of samples. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - September 13, 2019 Category: Biology Source Type: research

Vulvovaginal Candidiasis among Symptomatic Women of Childbearing Age attended at a Medical Analysis Laboratory in Franceville, Gabon
Conclusion: This study offers the first estimation of VVC among Gabonese women in childbearing age with the symptoms. It showed that VVC is very common in Gabon. C. albicans as the most commonly represented species (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - August 29, 2019 Category: Biology Source Type: research

Anti-fungal susceptibility and virulence factors of Candida spp. isolated from blood cultures
This study aims to investigate anti-fungal drug susceptibility, enzymatic activity and biofilm formation of the Candida spp. isolated from blood cultures. In 2016, a total of 84 clinical Candida isolates were analyzed for minimum inhibitory concentration (MIC) against fluconazole and amphotericin B by agar diffusion E-test (E-strips). Three enzymatic activity tests for phospholipase, proteinase and esterase were performed by using egg yolk agar, bovine serum albumin medium and Tween 80 opacity medium, respectively. Biofilm formation was determined by crystal violet staining. To describing the various Candida distributions ...
Source: Journal of Medical Mycology - August 23, 2019 Category: Biology Source Type: research

Saksenaea vasiformis infections: A case of an immunocompetent adult after mild injury and a literature review
Publication date: Available online 25 July 2019Source: Journal de Mycologie MédicaleAuthor(s): K. Samaras, A.-M. Markantonatou, D. Karapiperis, P. Digonis, N. Kartalis, N. Kostogloudis, T.-A. VyzantiadisAbstractSaksenaea vasiformis is an emerging human pathogen, belonging to the order Mucorales of the subphylum Mucormycotina, most often associated with rhino-cerebral, cutaneous and subcutaneous infections following trauma. A review of the published literature was attempted on the occasion of a cutaneous leg infection with favorable outcome in a young immunocompetent man after mild injury. The overall aim was the fac...
Source: Journal of Medical Mycology - August 22, 2019 Category: Biology Source Type: research

In vitro activity of carvacrol, cinnamaldehyde and thymol combined with antifungals against Malassezia pachydermatis
In conclusion, the results obtained indicate that the phytochemicals tested showed relevant in vitro anti-M. pachydermatis activity. Future in vivo experiments are needed to elucidate the safety and therapeutic potential of these combinations.RésuméMalassezia pachydermatis est un agent opportuniste important de la dermatite et de l'otite chez le chien. M. pachydermatis est généralement traité au moyen de traitements topiques utilisant une combinaison d'agents antifongiques, antimicrobiens et anti-inflammatoires. Nous avons étudié les activités in vitro du carvacrol (C...
Source: Journal of Medical Mycology - August 20, 2019 Category: Biology Source Type: research

Candidemia in a Portuguese tertiary care hospital: Analysis of a 2-year period
Conclusion: The distribution of Candida species has changed in recent years, with an increase in the proportion of C. albicans and C. glabrata. Rapid diagnostic tests, empiric antifungal therapy and source control are essential to improve the prognosis of patients with candidemia. More multicentric prospective studies are needed to evaluate the association of mortality with the timing of antifungal therapy or the EQUAL Candida Score. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - August 16, 2019 Category: Biology Source Type: research

Antifungal susceptibility and virulence factors of Candida spp. isolated from blood cultures
This study aims to investigate antifungal drug susceptibility, enzymatic activity and biofilm formation of the Candida spp. isolated from blood cultures. In 2016, a total of 84 clinical Candida isolates were analyzed for minimum inhibitory concentration (MIC) against fluconazole and amphotericin B by agar diffusion E-test (E strips). Three enzymatic activity tests for phospholipase, proteinase and esterase were performed by using egg yolk agar, bovine serum albumin medium and Tween 80 opacity medium, respectively. Biofilm formation was determined by crystal violet staining. To describing the various Candida distributions c...
Source: Journal of Medical Mycology - August 7, 2019 Category: Biology Source Type: research

Insights on the anticandidal activity of non-antifungal drugs
Publication date: Available online 27 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Daniel Clemente de Moraes, Antonio Ferreira-PereiraAbstractThe search for new antifungal strategies to overcome Candida infections is essential and a matter of public health, due to the high mortality associated to candidiasis, the increasing incidence of resistance to antifungals and the limited number of drugs available for treatment. Several approaches have been exploited in order to develop new antifungal strategies, e.g. the use of natural products, vaccines, and the combination of an antifungal drug to a non-antifung...
Source: Journal of Medical Mycology - July 28, 2019 Category: Biology Source Type: research

Fatal Cryptococcal Meningitis In A Child With Hyper-Immunoglobulin M Syndrome, With An Emphasis On The Agent
Publication date: Available online 26 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Simone Mancini Liduário Suzuki, Fabrício Morelli, Melyssa Negri, Patricia Bonfim-Mendonça, Érika Seki Kioshima, Tania Salci, Morgana Ferreira Voidaleski, Vânia Aparecida Vicente, Terezinha SvidzinskiAbstractFollowing a fatal case of Cryptococcus neoformans meningitis in a child with X-linked hyper-immunoglobulin M syndrome (XHIGM), we evaluated the fungal isolate in an experimental infection in a mouse model with respect to microbiology, epidemiology, virulence and response to therapy. The...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

Retrograde signaling disruption influences ABC superfamily transporter, ergosterol and chitin levels along with biofilm formation in Candida albicans
Conclusion: Present study establishes a link between RTG signaling, drug efflux and biofilm formation and validates CaRTG3 as antifungal target. Intricate studies are needed to further understand and exploit this therapeutic opportunity. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

Anesthetic Management of Rhinoorbitocerebral Mucormycosis; Focus on Challenges
This study aimed to evaluate the anesthetic management of patients undergoing surgical resection for rhino-orbito-cerebral mucormycosis (ROC).The study evaluated 12 patients that underwent surgical resection for ROC mucormycosis under general anesthesia. Demographic characteristics, hemodynamic parameters, invasive monitoring methods, surgical procedures, hospital records, and mortality rates were reviewed for each patient.The patients had a median age of 58 (range, 5-86) years. Two patients had an American Society of Anesthesiologists (ASA) score of II while the remaining 10 patients had a score of III. Eleven (91.7%) pat...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

Saksenaea vasiformis infections: a review of the published literature
Publication date: Available online 25 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Konstantinos Samaras, Anthi-Marina Markantonatou, Dimitrios Karapiperis, Polidoros Digonis, Nikolaos Kartalis, Nikolaos Kostogloudis, Timoleon-Achilleas VyzantiadisAbstractSaksenaea vasiformis is an emerging human pathogen, belonging to the order Mucorales of the subphylum Mucormycotina, most often associated with rhino-cerebral, cutaneous and subcutaneous infections following trauma. A review of the published literature was attempted on the occasion of a cutaneous leg infection with favorable outcome in a young immunocomp...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

The epidemiology of Candida species in the Middle East and North Africa
Publication date: Available online 26 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Sara Ghazi, Rayane Rafei, Marwan Osman, Dima El Safadi, Hassan Mallat, Nicolas Papon, Fouad Dabboussi, Jean-Philippe Bouchara, Monzer HamzeAbstractIn recent decades, the epidemiology of invasive candidiasis (IC) has progressively changed worldwide. This notably includes emergence of several Candida species. Although some surveillance programs provided global trends in IC epidemiology, data from countries from the Middle East and North Africa (MENA) remain scarce. In this manuscript, we reviewed the existing available data ...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

Mode of action and anti-Candida activity of Artemisia annua mediated-synthesized silver nanoparticles
Publication date: Available online 26 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Nafeesa Khatoon, Yamini Sharma, Meryam Sardar, Nikhat ManzoorAbstractCandida albicans is a polymorphic opportunistic commensal that causes both superficial and systemic fungal infections especially in immunocompromised patients. Biologically synthesized silver nanoparticles (AgNPs) have emerged as potential antifungal agents. The present work evaluates the antifungal activity of Artemisia annua synthesized AgNPs against three Candida species (C. albicans ATCC 90028, C. tropicalis ATCC 750 and C. glabrata ATCC 90030). The i...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research

A systematic review and meta-analysis on the epidemiology, casual agents and demographic characteristics of onychomycosis in Iran
Publication date: Available online 5 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Z. Rafat, S.J. Hashemi, A.-A. Saboor-Yaraghi, B. Pouragha, A. Taheriniya, A. Moosavi, B. Roohi, R. Arjmand, A. Moradi, R. Daie-Ghazvini, S. BasiriAbstractOnychomycosis or fungal nail infection is one of the most common fungal infections. Nearly 50% of all nail disorders are caused by fungi. This systematic review and meta-analysis was conducted to determine the prevalence of onychomycosis across Iran. We searched English and Persian databases for studies reporting the epidemiologic features of onychomycosis in Iranian peopl...
Source: Journal of Medical Mycology - July 7, 2019 Category: Biology Source Type: research

Inhibition of the growth of human dermatophytic pathogens by selected australian and asian plants traditionally used to treat fungal infections
ConclusionWhilst multiple extracts inhibited fungal growth, the methanolic S. australe and S. luehmannii leaf extracts and the S. luehmannii fruit extracts showed particularly potent activity against each of these dermatophytes, indicating that they are promising leads for the development of anti-dermatophytic therapeutics. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 25, 2019 Category: Biology Source Type: research

Interactions between oral commensal Candida and oral bacterial communities in immunocompromised and healthy children
This study focused on the first step of cooperation between microorganisms isolated from the same oral flora either of leukemic or healthy children. C. albicans isolated from 8/20 children were cultured to display their noninvasive blastosporic yeast form and mixed with their dominant bacteria to study the capacity of planktonic aggregation and the early state of biofilm formation. None of the dominant bacteria opposed the presence of yeast, on the contrary, an interesting cooperation was observed. This behavior is apparently different from that observed when mixing the type strains. In fact, three mutated C. alb...
Source: Journal of Medical Mycology - June 22, 2019 Category: Biology Source Type: research

In vitro expression of vital virulent genes of clinical and environmental isolates of Cryptococcus neoformans/gattii in endothelial cells of human blood-brain barrier
ConclusionThe C. gattii (VGI) isolates showed significantly lower invasion and survival than C. neoformans (VNI, and VNII) irrespective of their sources. Clinical isolates exhibited higher expression for the majority of the virulent genes until 12 hours of infection, probably due to their better adaptation in the host system and enhanced pathogenicity than the environmental counterparts. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 18, 2019 Category: Biology Source Type: research

Epidemiology and antifungal susceptibility testing of non-albicans Candida species colonizing mucosae of HIV-infected patients in Yaoundé (Cameroon)
Publication date: Available online 14 June 2019Source: Journal de Mycologie MédicaleAuthor(s): T.K. Ngouana, R.M.K. Toghueo, I.F. Kenfack, L. Lachaud, A.K. Nana, L. Tadjou, C. Kouanfack, F.F. Boyom, S. BertoutAbstractNon-albicans Candida (NAC) species have emerged as potent pathogenic yeasts among HIV-infected patients. Authors evaluated the epidemiology and antifungal susceptibility testing of non-albicans Candida species colonizing Yaoundé (capital of the Republic of Cameroon, Central Africa) HIV-infected patients. The mucosal specimens were collected and submitted to the mycological diagnosis. Yeast isolat...
Source: Journal of Medical Mycology - June 15, 2019 Category: Biology Source Type: research

Disseminated fungal infection due to Saprochaete clavata in a kidney transplant recipient
Publication date: Available online 13 June 2019Source: Journal de Mycologie MédicaleAuthor(s): P. Pavone, A. Oliva, G. Raponi, F. Pugliese, S. Martelli, P. Celli, F. Sacco, V. Vullo, C.M. Mastroianni, G. RussoAbstractSaprochaete clavata and Saprochaete capitata are closely related fungal species (family Dipodascaceae, order Saccharomycetales) that are rarely involved in the etiology of systemic infections in humans. In recent years, these yeasts are emerging as cause of life-threatening infections in patients with severe neutropenia and haematological malignancies. Infections by these fungi have been reported mostly...
Source: Journal of Medical Mycology - June 13, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: June 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 2Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 8, 2019 Category: Biology Source Type: research

Candida auris, an emerging and disturbing yeast
Publication date: June 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 2Author(s): A.T. Coste, C. Imbert, C. Hennequin (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 8, 2019 Category: Biology Source Type: research

Cladosporium sphaerospermum causing brain abscess, a saprophyte turning pathogen: Case and review of published reports
Publication date: Available online 2 May 2019Source: Journal de Mycologie MédicaleAuthor(s): N. Batra, H. Kaur, S. Mohindra, S. Singh, A.S. Shamanth, S.M. RudramurthyAbstractEmergence of saprophytic fungi thriving in dead plant material and soil as opportunistic human pathogens is of great concern. Cladosporium species are environmental saprophytes reported to cause various superficial and invasive fungal infections worldwide. C. sphaerospermum, a predominantly indoor fungus has been reported from cases of meningitis, subcutaneous and pulmonary fungal infections in the past. Herein we report the first case of c...
Source: Journal of Medical Mycology - May 4, 2019 Category: Biology Source Type: research

Detection of Pneumocystis jirovecii by quantitative real-time PCR in oral rinses from Pneumocystis pneumonia asymptomatic human immunodeficiency virus patients
In conclusion, although rare, a positive oral rinse P. jirovecii result may reflect colonisation, in particular in patients with HIV. This needs to be kept in mind when using oral rinses and qRT-PCR in the diagnosis of P. jirovecii infection. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - May 1, 2019 Category: Biology Source Type: research

Methods for identification of Candida auris, the yeast of global public health concern: A review
Publication date: Available online 26 April 2019Source: Journal de Mycologie MédicaleAuthor(s): S. Mahmoudi, S. Agha Kuchak Afshari, S. Aghaei Gharehbolagh, H. Mirhendi, K. MakimuraAbstractCandida auris has recently emerged as a fungus able to cause severe infections, especially bloodstream infections with high mortality rates. This multi-drug-resistant yeast has the capacity of persistence on environmental surfaces, and has been reported to cause hospital-acquired infections. The development of faster and inexpensive tools for identification is critical to controlling, preventing and establishing early diagnosis of...
Source: Journal of Medical Mycology - April 26, 2019 Category: Biology Source Type: research

Activity of base analogues (5-fluorouracil, 5-flucytosine) against planktonic cells and mature biofilm of Candida yeast. Effect of combination with folinic acid
In this study, the antifungal activity of base analogues, 5-flucytosine (5-FC) and 5-fluorouracil (5-FU), was tested against planktonic cells as well as against mature biofilm.MethodsTests were performed according the EUCAST methodology. Antibiofilm effectiveness of tested drugs was determined by the crystal violet staining method. The cytotoxicity assays was performed according to the ISO 10993-5 norm.Results5-FC and 5-FU were effective against fifteen fluconazole resistant Candida glabrata strains with an average minimal inhibitory concentration (MIC) of 0.152 mg/L and 0.39 mg/L, respectively. Folinic acid (fol...
Source: Journal of Medical Mycology - April 23, 2019 Category: Biology Source Type: research

Recurrent vulvo-vaginal candidiasis in Abidjan (Côte d’Ivoire): Aetiology and associated factors
Publication date: Available online 19 April 2019Source: Journal de Mycologie MédicaleAuthor(s): V. Djohan, K.E. Angora, A.H. Vanga-Bosson, A. Konaté, K.F. Kassi, P.C.M. Kiki-Barro, A.V. Bedia-Tanoh, S. Miezan, E.I.H. Menan, W. YavoAbstractRecurrent vulvovaginal candidiasis (RVVC) is a major health problem for sexually active women because of its severe effect on their quality of life. A thorough knowledge of their epidemiology leads to their efficient management. Therefore, a cross-sectional study was conducted in 2014 in women with leucorrhoea associated or not with other clinical signs. Recurrence was based...
Source: Journal of Medical Mycology - April 20, 2019 Category: Biology Source Type: research

Susceptibility profile of Candida rugosa (Diutina rugosa) against antifungals and compounds of essential oils
Publication date: Available online 5 April 2019Source: Journal de Mycologie MédicaleAuthor(s): A. Ludwig, F.P.K. de Jesus, V. Dutra, S.L. Cândido, S.H. Alves, J.M. SanturioAbstractCandida rugosa (recently reclassified Diutina rugosa) is an emerging pathogen affecting humans and animals. Candida resistance to existing drugs is an important factor to be monitored, as well as the need of researching alternatives to conventional antifungals. Here, we evaluated the in vitro effects of some antifungals and major components of essential oils by the broth microdilution method (CLSI M27-A3) against fifteen C. rugo...
Source: Journal of Medical Mycology - April 7, 2019 Category: Biology Source Type: research

Dermatophytic mycetoma of the scalp due to an atypical strain of Microsporum audouinii identified by MALDI-TOF MS and ITS sequencing
Publication date: Available online 5 April 2019Source: Journal de Mycologie MédicaleAuthor(s): K. Diongue, A. Boye, L. Bréchard, M.A. Diallo, H. Dione, N.W. Ndoye, M. Diallo, S. Ranque, D. NdiayeAbstractDermatophytic mycetoma of the scalp is a rarity, especially when not associated with tinea capitis. Here, we report a case of dermatophytic mycetoma of the scalp, that was not associated with tinea capitis, caused by an atypical Microsporum audouinii strain. To our knowledge, this is the second reported case, thirty-eight years after the first that was published in 1980. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - April 7, 2019 Category: Biology Source Type: research

Page informations
Publication date: April 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 1Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - March 28, 2019 Category: Biology Source Type: research

Editorial Board
Publication date: April 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 1Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - March 28, 2019 Category: Biology Source Type: research