Chemical composition, antioxidant activity and antifungal effects of five Iranian essential oils against Candida strains isolated from urine samples
This study reported the chemical composition, antioxidant and anti-Candida activity of Origanum majorana, Artemisia dracunculus, Cymbopogon citrate, Cinnamomum verum and Caryophyllus aromaticus essential oils. Different Candida species, from urine tracts of hospitalized patients, were included to be challenged with understudied essential oils. Chemical compositions were determined using gas chromatography/mass spectroscopy (GC/MS) analysis and antioxidant activity was measured using DDPH assay. MIC of these essential oils was evaluated using broth micro-dilution test. Caryophyllus aromaticus had the highest antioxidant act...
Source: Journal of Medical Mycology - February 22, 2018 Category: Biology Source Type: research

Optimization of essential oil-based natural disinfectants against Listeria monocytogenes and Escherichia coli biofilms formed on polypropylene surfaces
In this study, the biofilm elimination effect of selected essential oils (cinnamon, marjoram, and thyme) was evaluated against immature and mature biofilms of Escherichia coli and Listeria monocytogenes formed on polypropylene (PP) surfaces. The Response Surface Box-Behnken Design (BBD) with three variables and 17 assays was used to optimize concentration of essential oils (EOs) (1.1–15.8mg/mL), disinfection time (10min), and level of pH (4.5‐7.5) in the EO-based disinfection solutions. The optimized disinfectants were used against 24-, and 168-hour old biofilms formed on PP surfaces, and were successful in elimination...
Source: Journal of Molecular Liquids - February 20, 2018 Category: Molecular Biology Source Type: research

Evaluation of the Antiproliferative Activity of Some Nanoparticulate Essential Oils Formulated in Microemulsion on Selected Human Carcinoma Cell Lines.
CONCLUSION: Some EOs and their microemulsions can potentially be used as natural adjuvant to cancer drugs. PMID: 29318975 [PubMed - as supplied by publisher] (Source: Current Clinical Pharmacology)
Source: Current Clinical Pharmacology - January 10, 2018 Category: Drugs & Pharmacology Authors: Abd-Rabou A, Edris AE Tags: Curr Clin Pharmacol Source Type: research

Diminished activation of the right Inferior Parietal Lobule as a neural substrate of impaired cartoon-jokes comprehension in schizophrenia outpatients
Impairments related to humor comprehension may be considered one of the most specific phenomena related to communication disorders in schizophrenia (Adamczyk et al., 2016). Despite behavioral evidence, to the best of our knowledge, there are only two neuroimaging (fMRI) studies to date concerning humor processing in schizophrenia. The first, a pictorial visual joke task study on the relatives of individuals with schizophrenia revealed Prefrontal Cortex hypofunction during Theory of Mind humor processing (Marjoram et al., 2006). (Source: Schizophrenia Research)
Source: Schizophrenia Research - January 9, 2018 Category: Psychiatry Authors: Przemys ław Adamczyk, Miroslaw Wyczesany, Aleksandra Domagalik, Kamil Cepuch, Artur Daren, Tadeusz Marek Tags: Letter to the Editor Source Type: research

Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes
(Source: Blood)
Source: Blood - December 28, 2017 Category: Hematology Authors: Marjoram, D., Cruz-Leal, Y., Bernardo, L., Le, N. P. L., Crispin, M., Yu, X., Uchikawa, M., Lazarus, A. H. Tags: Transfusion Medicine Letter to Blood Source Type: research

Sub-inhibitory concentration of essential oils induces antibiotic resistance in Staphylococcus aureus.
Abstract Fourteen Staphylococcus aureus wild strains were stressed with sub-inhibitory concentration of five essential oils: Leptospermum scoparium (manuka), Origanum majorana (marjoram), Origanum vulgare (oregano), Satureja montana (winter savoury) and Thymus vulgaris (thyme). Antibiotics susceptibility profiles of the strains were determined by agar disk diffusion method before and after EOs treatment. The following antibiotics were employed: amoxicillin-clavulanic acid, amikacin, ampicillin, amoxicillin, aztreonam, ceftazidime, cephalothin, ciprofloxacin, colistin, cefotaxime, doxycycline, enrofloxacin,...
Source: Natural Product Research - December 22, 2017 Category: Biochemistry Authors: Turchi B, Mancini S, Pistelli L, Najar B, Fratini F Tags: Nat Prod Res Source Type: research

Molecules, Vol. 22, Pages 1887: Chemical Composition of Herbal Macerates and Corresponding Commercial Essential Oils and Their Effect on Bacteria Escherichia coli
This study addresses the chemical composition of some commercial essential oils (clove, juniper, oregano, and marjoram oils), as well as appropriate herbal extracts obtained in the process of cold maceration and their biological activity against selected Escherichia coli strains: E. coli ATTC 25922, E. coli ATTC 10536, and E. coli 127 isolated from poultry waste. On the basis of the gas chromatography-mass spectrometry (GCMS) analysis, it was found that the commercial essential oils revealed considerable differences in terms of the composition and diversity of terpenes, terpenoids and sesquiterpenes as compared with the ex...
Source: Molecules - November 10, 2017 Category: Chemistry Authors: Marietta Bia łoń Teresa Krzy śko-Łupicka Agnieszka Pik Piotr Wieczorek Tags: Article Source Type: research

Enhancing blood donor skin disinfection using natural oils.
CONCLUSION: The anti-biofilm activity of chlorhexidine-gluconate plus isopropyl alcohol can be greatly enhanced by L. multifida oil or linalool. Therefore, these components could potentially be used to improve blood donor skin disinfection. PMID: 28905380 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - September 14, 2017 Category: Hematology Authors: Alabdullatif M, Boujezza I, Mekni M, Taha M, Kumaran D, Yi QL, Landoulsi A, Ramirez-Arcos S Tags: Transfusion Source Type: research

Dynamics of culturable mesophilic bacterial communities of three fresh herbs and their production environment
ConclusionsOverall, culturable mesophilic bacteria were dominated by Pseudomonas spp. and Bacillus spp., with increased numbers on market‐ready products. Selected food contaminating bacteria were readily detectable, however, only the B. cereus group was found throughout in all systems. Significance and Impact of the StudyInsight into composition and development of mesophilic bacterial communities and selected food contaminating bacteria of fresh herbs contributes to estimating consumer exposure.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Source: Journal of Applied Microbiology - July 14, 2017 Category: Microbiology Authors: Maria ‐Theresia Gekenidis, Diane Gossin, Mathias Schmelcher, Ulrich Schöner, Mitja N. P Remus‐Emsermann, David Drissner Tags: Original Article Source Type: research

Chemical composition and cytotoxicity of extracts of marjoram and rosemary and their activity against Sporothrix brasiliensis.
CONCLUSION: These findings support the potential usefulness of the HAE of marjoram in the treatment of sporotrichosis. PMID: 28699881 [PubMed - as supplied by publisher] (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - July 12, 2017 Category: Microbiology Authors: Waller SB, Madrid IM, Hoffmann JF, Picoli T, Cleff MB, Chaves FC, Faria RO, Meireles MCA, Braga de Mello JR Tags: J Med Microbiol Source Type: research

Sure enough: efficient Bayesian learning and choice.
Abstract Probabilistic decision-making is a general phenomenon in animal behavior, and has often been interpreted to reflect the relative certainty of animals' beliefs. Extensive neurological and behavioral results increasingly suggest that animal beliefs may be represented as probability distributions, with explicit accounting of uncertainty. Accordingly, we develop a model that describes decision-making in a manner consistent with this understanding of neuronal function in learning and conditioning. This first-order Markov, recursive Bayesian algorithm is as parsimonious as its minimalist point-estimate,...
Source: Animal Cognition - July 1, 2017 Category: Zoology Authors: Foley BR, Marjoram P Tags: Anim Cogn Source Type: research

The repellent efficacy of eleven essential oils against adult Dermacentor reticulatus ticks
Publication date: Available online 15 June 2017 Source:Ticks and Tick-borne Diseases Author(s): Katarína Štefanidesová, Ľudovít Škultéty, Olivier A.E. Sparagano, Eva Špitalská Dermacentor reticulatus ticks are among the most important arthropod vectors of zoonotic disease agents in Europe. Eleven essential oils, namely basil (Ocimum basilicum), bergamot (Citrus bergamia), clove bud (Syzygium aromaticum), citronella (Cymbopogon winterianus), creeping thyme (Thymus serpyllum), lavender (Lavandula angustifolia), lemon-scented gum (Corymbia citriodora), marjoram (Origanum majorana), peppermint (Mentha piperita),...
Source: Ticks and Tick borne Diseases - June 16, 2017 Category: Zoology Source Type: research

Sub-inhibitory stress with essential oil affects enterotoxins production and essential oil susceptibility in Staphylococcus aureus.
Abstract Fourteen wild strains of Staphylococcus aureus positive for gene sea were tested for enterotoxins production and the minimum inhibitory concentration of Leptospermum scoparium, Origanum majorana, Origanum vulgare, Satureja montana and Thymus vulgaris essential oils (EOs) were determined. After this trial, bacteria stressed with sub-inhibitory concentration of each EO were tested for enterotoxins production by an immunoenzymatic assay and resistance to the same EO. Oregano oil exhibited the highest antibacterial activity followed by manuka and thyme oils. After the exposure to a sub-inhibitory conc...
Source: Natural Product Research - June 8, 2017 Category: Biochemistry Authors: Turchi B, Mancini S, Pistelli L, Najar B, Cerri D, Fratini F Tags: Nat Prod Res Source Type: research

TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone
by Cody J. Smith, Michael A. Wheeler, Lindsay Marjoram, Michel Bagnat, Christopher D. Deppmann, Sarah Kucenas Somatosensory information from the periphery is routed to the spinal cord through centrally-projecting sensory axons that cross into the central nervous system (CNS) via the dorsal root entry zone (DREZ). The glial cells that ensheath these axons ensure rapid propagation of this information. Despi te the importance of this glial-axon arrangement, how this afferent nerve is assembled during development is unknown. Usingin vivo, time-lapse imaging we show that as centrally-projecting pioneer axons from dorsal root g...
Source: PLoS Genetics - April 5, 2017 Category: Genetics & Stem Cells Authors: Cody J. Smith Source Type: research