Lumbar degenerative spondylolisthesis: factors associated with the decision to fuse
The indication to perform a fusion and decompression surgery as opposed to decompression alone for lumbar degenerative spondylolisthesis (LDS) remains controversial. A variety of factors are considered when deciding on whether to fuse, including patient demographics, radiographic parameters, and symptom presentation. Likely surgeon preference has an important influence as well. (Source: The Spine Journal)
Source: The Spine Journal - November 25, 2020 Category: Orthopaedics Authors: Nicole Schneider, Charles Fisher, Andrew Glennie, Jennifer Urquhart, John Street, Marcel Dvorak, Scott Paquette, Raphaele Charest-Morin, Tamir Ailon, Neil Manson, Ken Thomas, Parham Rasoulinejad, Raja Rampersaud, Chris Bailey Tags: Clinical Study Source Type: research

Predictive model of Ischemic optic neuropathy in spinal fusion surgery using a longitudinal medical claims database
Perioperative ischemic optic neuropathy (ION) is a devastating complication of spinal fusion surgery. (Source: The Spine Journal)
Source: The Spine Journal - November 25, 2020 Category: Orthopaedics Authors: Heather E. Moss, Lan Xiao, Shikhar H. Shah, Yi-Fan Chen, Charlotte Joslin, Steven Roth Tags: Clinical Study Source Type: research

National Utilization and Inpatient Safety Measures of Lumbar Spinal Fusion Methods by Race/Ethnicity
Degenerative lumbar conditions are prevalent, disabling, and often associated with loss of structural integrity, including spondylolisthesis, degenerative scoliosis, or instability1,2. If nonoperative treatment is unsuccessful, these conditions are frequently managed with surgical decompression and fusion3,4. Elective lumbar spinal fusion is an increasingly common procedure in the United States5,6. Several fusion methods are available, with varying complexity, invasiveness, and cost. The literature is inconclusive on whether any of these procedures results in better safety measures than the others7 –9. (Source: The Spine Journal)
Source: The Spine Journal - November 19, 2020 Category: Orthopaedics Authors: Angel M. Reyes, Jeffrey N. Katz, Andrew J. Schoenfeld, James D. Kang, Elena Losina, Yuchiao Chang Source Type: research

Surgical Plans Generated from Telemedicine Visits are Rarely Changed after In Person Evaluation in Spine Patients
Telemedicine has the potential to deliver substantial value to spine and orthopaedic patients, through greater convenience, removal of geographic barriers to care, and the ability to obtain diagnosis and treatment recommendations without leaving their home.   For institutions, the ability to deliver care at lower cost and scale services beyond typical geographic proximity limitations is similarly advantageous. In spite of the substantial value and advantages of telemedicine, adoption has been limited by platform technology development, regulatory issu es, medicolegal concerns, and payer reimbursement [1,2]. (Source: The Spine Journal)
Source: The Spine Journal - November 19, 2020 Category: Orthopaedics Authors: Harry M. Lightsey, Alexander M. Crawford, Grace X. Xiong, Andrew J. Schoenfeld, Andrew K. Simpson Source Type: research

Spring Distraction System for Dynamic Growth Guidance of Early Onset Scoliosis: 2 Year Prospective Follow-up of 24 Patients.
Current surgical treatment options for Early Onset Scoliosis (EOS), with distraction-based implants or growth-guidance systems, show limited growth and high complication rates during follow-up. We developed a novel implant concept, which uses compressed helical springs positioned around the rods of a growth-guidance construct. This Spring Distraction System (SDS) provides continuous corrective force to stimulate spinal growth, can be easily contoured, and can be used with all standard spinal instrumentation systems. (Source: The Spine Journal)
Source: The Spine Journal - November 19, 2020 Category: Orthopaedics Authors: Justin V.C. Lemans, Sebastiaan P.J. Wijdicks, Ren é M. Castelein, Moyo C. Kruyt Tags: Clinical Study Source Type: research

The Patient Acceptable Symptom State for the Oswestry Disability Index Following Single-level Lumbar Fusion for Degenerative Spondylolisthesis
The patient acceptable symptom state (PASS) is a valuable tool for interpreting patient-reported outcomes. Previous studies have attempted to define the PASS in a heterogenous cohort with various lumbar spinal disorders and surgical procedures. (Source: The Spine Journal)
Source: The Spine Journal - November 19, 2020 Category: Orthopaedics Authors: Graham S. Goh, Reuben Chee Cheong Soh, Wai-Mun Yue, Chang-Ming Guo, Seang-Beng Tan, John Li-Tat Chen Tags: Clinical Study Source Type: research

Level the Playing Field: A Fish Can Breathe Air
My colleagues and I published the results of a randomized controlled trial a few years ago. [1] We compared short versus long restrictions after lumbar discectomy. It sounds like a level I study, right? Think again. (Source: The Spine Journal)
Source: The Spine Journal - November 17, 2020 Category: Orthopaedics Authors: Christopher M. Bono Tags: Editorial Source Type: research

Corrigendum to ‘The lumbar autonomic nerves in male: A few anatomical insights into anterior lumbar interbody fusion’ [The Spine Journal 20/12 (2002) p2006–2013]
This published article entitled “The lumbar autonomic nerves in male:A few anatomical insights into anterior lumbar interbody fusion (No. SPINEE-D-20-00280R3) ” has been checked by experienced statistician again. Some statistical analyse were observed unreasonable. Here, the authors want to revise the 4th paragraph of the Mate rials and methods “The distribution of the locations of the initial sites of each LSN and the angles formed by the LSNs and the vertical axis were assessed with the Kruskal−Wallis test. (Source: The Spine Journal)
Source: The Spine Journal - November 13, 2020 Category: Orthopaedics Authors: Shangxi Deng, Qinghao Zhao, Changsheng Yang, Rui Peng, Jianjun Zhao, Enyi Zhong, Baohua Luo, Jianheng Luo, Zezheng Liu, Qingchu Li Tags: Corrigendum Source Type: research

Manuscript Characteristics Associated with the Altmetrics Score and Social Media Presence: An Analysis of Seven Spine Journals
Impact factor, citation rate, and other traditional measures of scholarly impact do not account for the role that social media has in the dissemination of research. The Altmetric Attention Score (AAS) quantifies the active online presence of individual articles on various platforms (e.g., Twitter, Facebook). (Source: The Spine Journal)
Source: The Spine Journal - November 13, 2020 Category: Orthopaedics Authors: Michelle A. Richardson, David N. Bernstein, Addisu Mesfin Tags: Clinical Study Source Type: research

Single position circumferential fusion improves operative efficiency, reduces complications and length of stay compared with traditional circumferential fusion
Anterior Lumbar Interbody Fusion (ALIF) and Lateral Lumbar Interbody Fusion (LLIF) with percutaneous posterior screw fixation are two techniques used to address degenerative lumbar pathologies. Traditionally, these anterior-posterior (AP) surgeries involve repositioning the patient from the supine or lateral decubitus position to prone for posterior fixation. To reduce operative time (OpTime) and subsequent complications of prolonged anesthesia, single-position lumbar surgery (SPLS) is a novel, minimally invasive alternative performed entirely from the lateral decubitus position. (Source: The Spine Journal)
Source: The Spine Journal - November 13, 2020 Category: Orthopaedics Authors: Aaron J. Buckland, Kimberly Ashayeri, Carlos Leon, Jordan Manning, Leon Eisen, Mark Medley, Themistocles S. Protopsaltis, J. Alex Thomas Tags: Clinical Study Source Type: research

How Do C2 Tilt and C2 Slope Correlate with Patient Reported Outcomes in Patients After ACDF?
C2 tilt and C2 slope are quick and easy measurements to obtain on lateral radiographs and may be used to determine overall cervical sagittal alignment; however, the influence of these measurements on patient outcomes has not been well established in literature. (Source: The Spine Journal)
Source: The Spine Journal - November 13, 2020 Category: Orthopaedics Authors: Srikanth N. Divi, Wesley H. Bronson, Jose A. Canseco, Michael Chang, Dhruv K.C. Goyal, Kristen J. Nicholson, Victor E. Mujica, I. David Kaye, Mark F. Kurd, Barrett I. Woods, Kristen E. Radcliff, Jeffrey A. Rihn, D. Greg Anderson, Alan S. Hilibrand, Christ Tags: Clinical Study Source Type: research

Does prophylactic use of topical gelatin-thrombin matrix sealant affect postoperative drainage volume and hematoma formation following microendoscopic spine surgery?: a randomized controlled trial
Microendoscopic spine surgery has been introduced and developed as a minimally invasive surgical method in recent years. In 1998, a minimally invasive laminotomy using a spinal microendoscope was developed and standardized to provide accurate lumbar decompression [1]. Microendoscopic laminotomy (MEL) has been increasingly utilized for the treatment of lumbar spinal stenosis and has demonstrated good clinical results [2]. MEL allows for adequate nerve decompression while maintaining maximum preservation of facet joints, posterior ligament complex, and soft tissues. (Source: The Spine Journal)
Source: The Spine Journal - November 13, 2020 Category: Orthopaedics Authors: Masanari Takami, Munehito Yoshida, Akihito Minamide, Hiroshi Hashizume, Yasutsugu Yukawa, Yukihiro Nakagawa, Hiroshi Iwasaki, Shunji Tsutsui, Keiji Nagata, Ryo Taiji, Hideto Nishi, Andrew J. Schoenfeld, Andrew K. Simpson, Hiroshi Yamada Tags: Clinical Article Source Type: research

Loading of the Lumbar Spine During Transition from Standing to Sitting: Effect of Fusion versus Motion Preservation at L4-L5 and L5-S1
Transition from standing to sitting significantly decreases lumbar lordosis with the greatest lordosis-loss occurring at L4-S1. Fusing L4-S1 eliminates motion and thus the proximal mobile segments maybe recruited during transition from standing to sitting to compensate for the loss of L4-S1 mobility. This may subject proximal segments to supra-physiologic flexion loading. (Source: The Spine Journal)
Source: The Spine Journal - November 4, 2020 Category: Orthopaedics Authors: Avinash G. Patwardhan, J. Alex Sielatycki, Robert M. Havey, S. Craig Humphreys, Scott D. Hodges, Kenneth R. Blank, Muturi G. Muriuki Tags: Basic Science Source Type: research

Laminoplasty —an underutilized procedure for cervical spondylotic myelopathy
Cervical spondylotic myelopathy (CSM) is a degenerative disease of the cervical spine that often results in progressive neurologic deterioration [1]. In order to halt the progression of symptoms, a canal expansion procedure is often performed [1 –4]. Several procedures have been described to treat this pathology; deciding which surgical technique to use depends on multiple factors such as patient profile, previous spinal surgery, source of compression, sagittal alignment, number of levels involved, and ultimately, surgeon preference [3, 4 ]. (Source: The Spine Journal)
Source: The Spine Journal - November 2, 2020 Category: Orthopaedics Authors: Wylie Y. Lopez, Brian C. Goh, Shivam Upadhyaya, Chason Ziino, Peter J. Georgakas, Anmol Gupta, Daniel G. Tobert, Harold A. Fogel, Thomas D. Cha, Joseph H. Schwab, Christopher M. Bono, Stuart H. Hershman Tags: Clinical Study Source Type: research

Analysis of the influence of species, intervertebral disc height and Pfirrmann classification on failure load of an injured disc using a novel disc herniation model
Annular repair devices offer a solution to recurrent disc herniations by closing an annular defect and lowering the risk of reherniation. Given the significant risk of neurologic injury from device failure it is imperative that a reliable preclinical model exists to demonstrate a high load to failure for the disc repair devices. (Source: The Spine Journal)
Source: The Spine Journal - November 2, 2020 Category: Orthopaedics Authors: Sohrab Virk, Kathleen N. Meyers, Virginie Lafage, Suzanne A. Maher, Tony Chen Tags: Basic Science Source Type: research

Postoperative Adverse Events Secondary to Iatrogenic Vascular Injury during Anterior Lumbar Spinal Surgery
Anterior lumbar spine surgery (ALSS) requires mobilization of the great vessels, resulting in a high risk of iatrogenic vascular injury (VI). It remains unclear whether VI is associated with increased risk of postoperative complications and other related adverse outcomes. (Source: The Spine Journal)
Source: The Spine Journal - November 2, 2020 Category: Orthopaedics Authors: Olivier Q. Groot, D. Hundersmarck, Amanda Lans, Michiel E.R. Bongers, Aditya V. Karhade, Y. Zhang, Floris. R. van Tol, Jorrit J. Verlaan, J. Mohebali, Joseph H. Schwab Tags: Clinical Study Source Type: research

Laminoplasty - An Underutilized Procedure for Cervical Spondylotic Myelopathy
Cervical spondylotic myelopathy (CSM) is a degenerative disease of the cervical spine that often results in progressive neurologic deterioration [1]. In order to halt the progression of symptoms, a canal expansion procedure is often performed [1-4]. Several procedures have been described to treat this pathology; deciding which surgical technique to use depends on multiple factors such as patient profile, previous spinal surgery, source of compression, sagittal alignment, number of levels involved, and ultimately, surgeon preference [3, 4]. (Source: The Spine Journal)
Source: The Spine Journal - November 2, 2020 Category: Orthopaedics Authors: Wylie Y. Lopez, Brian C. Goh, Shivam Upadhyaya, Chason Ziino, Peter J. Georgakas, Anmol Gupta, Daniel G. Tobert, Harold A. Fogel, Thomas D. Cha, Joseph H. Schwab, Christopher M. Bono, Stuart H. Hershman Tags: Clinical Study Source Type: research

Morphology and Growth of the Pediatric Lumbar Vertebrae
The majority of existing literature describing pediatric lumbar vertebral morphology are limited to characterization of the vertebral bodies, pedicles, and spinal canal and no study has described the rates of growth for any lumbar vertebral structure. While it is known that growth of the lumbar vertebrae results in changes in vertebral shape, the dimension ratios used to quantify these shape changes do not represent the 3D morphology of the vertebral structures. Additionally, many of the previous evaluations of growth and shape are purely descriptive and do not investigate sexual dimorphism or variations across vertebral l...
Source: The Spine Journal - November 2, 2020 Category: Orthopaedics Authors: James R. Peters, Sabah Servaes, Patrick Cahill, Sriram Balasubramanian Tags: Basic Science Source Type: research

Letter to the editor concerning “Sarcopenia, but not frailty, predicts early mortality and adverse events after emergent surgery for metastatic disease of the spine” by Bourassa-Moreau E, et al. (Spine J. 2020; 20(1):22-31)
We read with avid interest the paper by Bourassa-Moreau et al. [1] regarding the ability of frailty and sarcopenia to independently predict early mortality and adverse events following urgent surgery for metastatic disease of the spine. The clinical importance of the paper is undisputed. However, we present the following considerations. (Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Authors: Xiaofeng Le, Dingjun Hao Tags: Letters to the editor Source Type: research

Letter to the editor regarding, “Preemptive analgesia with a single low dose of intrathecal morphine in multilevel posterior lumbar interbody fusion surgery: a double-blind, randomized, controlled trial,” by Wang et al
In this study, the authors suggest that the use of intrathecal morphine (ITM) for analgesia in advance c an notably improve early postoperative pain control and reduce the consumption of postoperative patient-controlled intravenous analgesia without increasing side effects. (Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Authors: Ze-Qing Huang, Yi Wang Tags: Letters to the editor Source Type: research

Response to Letter to the Editor regarding, “potential significance of facet joint fusion or posteromedial fusion observed on CT imaging following attempted posterolateral or posterior interbody fusion”
We appreciate Farrohki et al. for their interest in our study of facet joint fusion and their thoughtful comments regarding the statistical methods employed. They suggest that the Friedman test would have been a more appropriate method as opposed to one-way ANOVA given analysis of three separate time points (preoperative, 6 months, and 12 months). The Friedman test is indeed considered a reasonable non-parametric alternative to the one-way ANOVA with repeated measures, but we have consulted another biostatistician in addition to our original statistician and both feel that the one-way ANOVA with repeated measures is a vali...
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Authors: David H. Kim, Raymond W. Hwang, Gyu-Ho Lee, Riya Joshi, Kevin C. Baker, Paul Arnold, Rick Sasso, Daniel Park, Jeffrey Fischgrund Tags: Letters to the editor Source Type: research

Letter to the editor regarding, “Potential significance of facet joint fusion or posteromedial fusion observed on CT imaging following attempted posterolateral or posterior interbody fusion” by Kim et al
We read with great interest a recent published article entitled, "Potential Significance of Facet Joint Fusion or Posteromedial Fusion Observed on CT Imaging Following Attempted Posterolateral or Posterior Interbody Fusion," which has been published in The Spine Journal [1]. The authors investigated some numerical variables in four groups in three time-points of measurement. The authors used a one-way analysis of variance (ANOVA) for comparison of numerical variables between groups and also for different time-points of measurement. (Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Authors: Mehrdad Farrokhi, Niloofar Alsadat Nourian, Sayed-Mohammad-Amin Nourian Tags: Letters to the Editor Source Type: research

Editorial Board
(Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Source Type: research

Table of Contents
(Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Source Type: research

Meetings Calendar
(Source: The Spine Journal)
Source: The Spine Journal - October 31, 2020 Category: Orthopaedics Source Type: research

Diversity, equity, inclusion, and bias: we can do better: NASS 2020 presidential address
Normally during our annual meeting, I would see many friends, colleagues and family in the audience in the main hall of a large convention center. Even without COVID, it is unlikely my mother would have been able to come, and my father passed away during the 2016 NASS meeting. But I think they would have liked this. (Source: The Spine Journal)
Source: The Spine Journal - October 29, 2020 Category: Orthopaedics Authors: William J. Sullivan Tags: Editorial Source Type: research

Development of prediction models for clinically meaningful improvement in PROMIS scores after lumbar decompression
The ability to preoperatively predict which patients will achieve a minimal clinically important difference (MCID) after lumbar spine decompression surgery can help determine the appropriateness and timing of surgery. Patient-Reported Outcome Measurement Information System (PROMIS) scores are an increasingly popular outcome instrument. (Source: The Spine Journal)
Source: The Spine Journal - October 29, 2020 Category: Orthopaedics Authors: Aditya V. Karhade, Harold A. Fogel, Thomas D. Cha, Stuart H. Hershman, Terence P. Doorly, James D. Kang, Christopher M. Bono, Mitchel B. Harris, Joseph H. Schwab, Daniel G. Tobert Tags: Clinical Study Source Type: research

Spinal trauma in DISH and AS: Is MRI essential following the detection of vertebral fractures on CT?
Biomechanical stability of the spine is altered in patients with a rigid spine, such as those with ankylosing spondylitis (AS) or diffuse idiopathic skeletal hyperostosis (DISH), rendering it vulnerable to fracture even after seemingly innocuous events such as low energy falls from standing or sitting [1,2]. CT and MRI are often recommended for both AS and DISH after a traumatic event [3]. The management of spinal fractures with DISH or AS has generally not been distinguished, with operative stabilization recommended for unstable injuries involving both the vertebral body and posterior elements. (Source: The Spine Journal)
Source: The Spine Journal - October 29, 2020 Category: Orthopaedics Authors: Nandish G Shah, Abhishek Keraliya, Mitchel B Harris, Christopher M Bono, Bharti Khurana Tags: Clinical Study Source Type: research

Diversity, Equity, Inclusion and Bias: We Can Do Better: NASS 2020 Presidential Address
Normally during our annual meeting, I would see many friends, colleagues and family in the audience in the main hall of a large convention center. Even without COVID, it is unlikely my mother would have been able to come, and my father passed away during the 2016 NASS meeting. But I think they would have liked this. (Source: The Spine Journal)
Source: The Spine Journal - October 29, 2020 Category: Orthopaedics Authors: William J. Sullivan, 2020 NASS President Tags: Perspective Source Type: research

Variations in the sagittal spinal profile precede the development of scoliosis: A pilot study of a new approach
Idiopathic scoliosis in man is believed to be related to the unique human sagittal profile. [1 –6] Patients with a thoracic scoliosis have a longer, more proximal, posteriorly inclined segment of the spine as compared to lumbar scoliosis and controls, whereas patients with a lumbar scoliosis have a more caudal, shorter and steeper posteriorly inclined segment. [7] One of the main problems i n etiological scoliosis research is the paucity of data on scoliosis patients before the onset, i.e. it is unknown whether associated factors are causative to the development of scoliosis. (Source: The Spine Journal)
Source: The Spine Journal - October 27, 2020 Category: Orthopaedics Authors: J.F. Homans, T.P.C. Schl össer, S. Pasha, M.C. Kruyt, R.M. Castelein Tags: Research Letter Source Type: research

A critical appraisal of clinical practice guidelines for the treatment of lumbar spinal stenosis
The aim of the review was to appraise clinical practice guidelines and their recommendations for the treatment of lumbar spinal stenosis. (Source: The Spine Journal)
Source: The Spine Journal - October 25, 2020 Category: Orthopaedics Authors: DB Anderson, K de Luca, RK Jensen, JP Eyles, JM Van Gelder, JL Friedly, CG Maher, ML Ferreira Tags: Review Article Source Type: research

Health Related Quality of Life Outcomes Following Surgery and/or Radiation For Patients with Potentially Unstable Spinal Metastases
Currently there is no prospective pain and health related quality of life (HRQOL) data of patients with potentially unstable spinal metastases who were treated with surgery+- radiation or radiation alone. (Source: The Spine Journal)
Source: The Spine Journal - October 21, 2020 Category: Orthopaedics Authors: A.L. Versteeg, A. Sahgal, L.D. Rhines, D.M. Sciubba, J.M. Schuster, M.H. Weber, A. Lazary, S. Boriani, C. Bettegowda, M.G. Fehlings, M.J. Clarke, P.M. Arnold, Z.L. Gokaslan, C.G. Fisher, AOSpine Knowledge Forum Tumor Tags: Clinical Study Source Type: research

Prospective, multicenter clinical trial comparing M6-C compressible six degrees of freedom cervical disc with anterior cervical discectomy and fusion for the treatment of single level degenerative cervical radiculopathy: Two- year results of an FDA investigational device exemption study
Various designs of total disc replacement (TDR) devices have been compared to ACDF with favorable outcomes in FDA-approved investigational device exemption (IDE) trials. The design of M6-C with a compressible viscoelastic nuclear core and an annular structure is substantially different than prior designs and has previously demonstrated favorable kinematics and clinical outcomes in small case series. (Source: The Spine Journal)
Source: The Spine Journal - October 20, 2020 Category: Orthopaedics Authors: Frank M. Phillips, Domagoj Coric, Rick Sasso, Todd Lanman, William Lavelle, Scott Blumenthal, Carl Lauryssen, Richard Guyer, Todd Albert, Jack Zigler, Frank Cammisa, Robert Alden Milam Tags: Clinical Study Source Type: research

Inclusion of L5 –S1 in oblique lumbar interbody fusion–techniques and early complications–a single center experience
Minimally invasive surgical techniques for lumbar degenerative disorders are conceived in hopes of reducing approach-related muscle damage and allowing quicker rehabilitation, while maintaining a low complication rate. Oblique lumbar interbody fusion (OLIF) is one such technique that provides a mini-open anterolateral retroperitoneal access to the lumbar spine [1,2]. This approach remains anterior to the psoas muscle and avoids injury to the lumbar plexus, which is a significant concern associated with the transpsoas or lateral lumbar interbody fusion technique [3 –8]. (Source: The Spine Journal)
Source: The Spine Journal - October 19, 2020 Category: Orthopaedics Authors: Chirag A. Berry, Dinesh P. Thawrani, Fadi R. Makhoul Tags: Clinical Study Source Type: research

Inclusion of L5-S1 in Oblique Lumbar Interbody Fusion - Techniques and Early Complications - A Single Center Experience
Minimally invasive surgical techniques for lumbar degenerative disorders are conceived in hopes of reducing approach-related muscle damage and allowing quicker rehabilitation, while maintaining a low complication rate. Oblique lumbar interbody fusion (OLIF) is one such technique that provides a mini-open anterolateral retroperitoneal access to the lumbar spine [1,2]. This approach remains anterior to the psoas muscle (ATP) and avoids injury to the lumbar plexus, which is a significant concern associated with the transpsoas or lateral lumbar interbody fusion (LLIF) technique [3-8]. (Source: The Spine Journal)
Source: The Spine Journal - October 19, 2020 Category: Orthopaedics Authors: Chirag A. Berry, Dinesh Thawrani, Fadi Makhoul Source Type: research

Evaluation of Transforaminal Epidural Steroid Injections for Discogenic Axial Lumbosacral Back Pain Utilizing PROMIS as an Outcome Measure
Discogenic lumbosacral back pain continues to present a challenging clinical entity with limited, controversial therapeutic options. No study to date has evaluated the efficacy of fluoroscopically guided transforaminal epidural steroid injections (TFESI) in a homogenous patient population with axial lumbosacral back pain from discogenic pathology utilizing strict, explicitly clinical and radiographic criteria. Additionally, there is a paucity of published data utilizing Patient Reported Outcome Measurement Information System (PROMIS) scores as an outcome measure for interventional spine procedures. (Source: The Spine Journal)
Source: The Spine Journal - October 19, 2020 Category: Orthopaedics Authors: Adam J. Michalik, Rajeev K. Patel Tags: linical Study Source Type: research

Relationships between anthropometric adiposity indexes and bone mineral density in a cross-sectional Chinese study
Previous studies have reported conflicting results for the relationships between anthropometric adiposity indexes and bone mineral density, based on dual-energy X-ray absorptiometry (DXA). However, few studies were published based on quantitative computed tomography (QCT), especially for Chinese population. (Source: The Spine Journal)
Source: The Spine Journal - October 19, 2020 Category: Orthopaedics Authors: Guijuan Deng, Lu Yin, Kai Li, Bo Hu, Xiaoru Cheng, Ling Wang, Yong Zhang, Li Xu, Shaoqi Xu, Lei Zhu, Jiman Shao, Xiaoguang Hao, Jun Zhou, Jinhua Tang, Wei Li, Yu Jiang, Xiaoguang Cheng Tags: Clinical Study Source Type: research

Comparison of Adverse Events Between Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion: A 10-year Follow-up
Anterior cervical discectomy and fusion (ACDF) with plating has been proven to be a successful procedure with good outcomes and high patient satisfaction.[1] Cervical disc arthroplasty (CDA) has the potential to reduce the risk of adjacent level disc degeneration and segmental instability that may be seen after a cervical fusion.[2-5] One of several cervical disc arthroplasty devices has undergone safety and effectiveness evaluation in the United States. It currently has one of the longest follow-up periods available for review. (Source: The Spine Journal)
Source: The Spine Journal - October 17, 2020 Category: Orthopaedics Authors: Travis Loidolt, Swamy Kurra, K. Daniel Riew, Allan D. Levi, Jeffrey Florman, William F Lavelle Source Type: research

Occult infection in pseudarthrosis revision after spinal fusion
Pseudarthrosis after attempted spinal fusion is yet not sufficiently understood and presents a surgical challenge. Occult infections are sometimes observed in patients with pseudarthrosis and no inflammatory signs of infection. The prevalence of such occult infection and its association with patient demographics and inflammatory markers are largely unknown. (Source: The Spine Journal)
Source: The Spine Journal - October 16, 2020 Category: Orthopaedics Authors: Marco D. Burkhard, Ruben Loretz, Ilker U çkay, David E. Bauer, Michael Betz, Mazda Farshad Tags: Clinical Study Source Type: research

A Cost Benefit Analysis of Increasing Surgical Technology in Lumbar Spine Fusion
Numerous advances have been made in the field of spine fusion, such as minimally invasive (MIS) or robotic-assisted spine surgery. However, it is unknown how these advances have impacted the cost of care. (Source: The Spine Journal)
Source: The Spine Journal - October 15, 2020 Category: Orthopaedics Authors: Peter G. Passias, Avery E. Brown, Haddy Alas, Cole A. Bortz, Katherine E. Pierce, Hamid Hassanzadeh, Lawal A. Labaran, Varun Puvanesarajah, Dennis Vasquez-Montes, Erik Wang, Rivka C. Ihejirika, Bassel G. Diebo, Virginie Lafage, Renaud Lafage, Daniel M. Sc Tags: Clinical Study Source Type: research

Spinal manipulation and perineural electrical dry needling in patients with cervicogenic headache: a multi-center randomized clinical trial
Spinal manipulation, spinal mobilization and exercise are commonly used in individuals with cervicogenic headache (CH). Dry needling is being increasingly used in the management of CH. However, questions remain about the effectiveness of these therapies and how they compare to each other. (Source: The Spine Journal)
Source: The Spine Journal - October 13, 2020 Category: Orthopaedics Authors: James Dunning, Raymond Butts, Noah Zacharko, Keith Fandry, Ian Young, Kenneth Wheeler, Jennell Day, C ésar Fernández-de-las-Peñas Tags: Clinical Study Source Type: research

Predictive Modeling of Long-Term Opioid and Benzodiazepine Use after Intradural Tumor Resection
Despite increased awareness of the ongoing opioid epidemic, opioid and benzodiazepine use remain high after spine surgery. In particular, long-term co-prescription of opioids and benzodiazepines have been linked to high risk of overdose-associated death. Tumor patients represent a unique subset of spine surgery patients and few studies have attempted to develop predictive models to anticipate long-term opioid and benzodiazepine use after spinal tumor resection. (Source: The Spine Journal)
Source: The Spine Journal - October 13, 2020 Category: Orthopaedics Authors: Michael C. Jin, Allen L. Ho, Austin Y. Feng, Yi Zhang, Victor E. Staartjes, Martin N. Stienen, Summer S. Han, Anand Veeravagu, John K. Ratliff, Atman M. Desai Source Type: research

Fostering Reproducibility and Generalizability in Machine Learning for Clinical Prediction Modeling in Spine Surgery
As the use of machine learning algorithms in the development of clinical prediction models has increased, researchers are becoming more aware of the deleterious that stem from the lack of reporting standards. One of the most obvious consequences is the insufficient reproducibility found in current prediction models. In an attempt to characterize methods to improve reproducibility and to allow for better clinical performance, we utilize a previously proposed taxonomy that separates reproducibility into three components: technical, statistical, and conceptual reproducibility. (Source: The Spine Journal)
Source: The Spine Journal - October 12, 2020 Category: Orthopaedics Authors: Tej D. Azad, Jeff Ehresman, A. Karim Ahmed, Victor E. Staartjes, Daniel Lubelski, Martin N. Stienen, Anand Veeravagu, John K. Ratliff Source Type: research

Are Outpatient Three- and Four-Level Anterior Cervical Discectomies and Fusion Safe?
The safety of outpatient one- and two-level anterior cervical discectomy and fusion (ACDF) has been validated in a number of recent studies. However, recent advancements in anesthetic and surgical technique have rendered procedures previously only performed in an inpatient setting, such as three- and four-level ACDF, potentially amenable to outpatient management. (Source: The Spine Journal)
Source: The Spine Journal - October 10, 2020 Category: Orthopaedics Authors: Venkat Boddapati, Justin Mathew, Nathan J Lee, Joel R Peterson, Kyle L McCormick, Joseph M Lombardi, Zeeshan M Sardar, Ronald A Lehman, K Daniel Riew Tags: Clinical Study Source Type: research

The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: A randomized controlled trial
Tranexamic acid (TXA) is widely used in surgery for adolescent idiopathic scoliosis (AIS) and has been proved to be efficacious in reducing intraoperative blood loss (IBL) and the transfusion rate. However, the routine TXA regimen was intraoperative administration alone, in which the concentration of TXA could not cover the whole process of hyperfibrinolysis. And, its ability to control the massive postoperative blood loss (PBL) may be insufficient. Thus, we promoted a multiple-dose regimen of TXA for patients with AIS who underwent surgical correction. (Source: The Spine Journal)
Source: The Spine Journal - October 10, 2020 Category: Orthopaedics Authors: Zhuang Zhang, Lin-nan Wang, Xi Yang, Li-min Liu, Peng Xiu, Zhong-jie Zhou, Lei Wang, Yue-ming Song Tags: Clinical Study Source Type: research

Structural spinal abnormalities on MRI and associations with weight status in a general pediatric population
Several spinal abnormalities have been studied using magnetic resonance imaging (MRI). However, in children these studies were sparsely performed in general populations. Examining young children's spines is important since the shape of the bone is largely determined during the growth spurt. Furthermore, it is so far unknown if associations between weight status and spinal abnormalities, which are known for adolescents and adults, are already present in young children. (Source: The Spine Journal)
Source: The Spine Journal - October 9, 2020 Category: Orthopaedics Authors: Marleen M. van den Heuvel, Edwin H.G. Oei, Jeroen J.M. Renkens, Sita M.A. Bierma-Zeinstra, Marienke van Middelkoop Tags: Clinical Study Source Type: research

Allogeneic Mesenchymal Precursor Cells Treatment for Chronic Low Back Pain Associated with Degenerative Disc Disease: A Prospective Randomized, Placebo-Controlled 36-Month Study of Safety and Efficacy
Evaluate the safety and efficacy of a single injection of STRO-3+ adult allogeneic mesenchymal precursor cells (MPCs) combined with hyaluronic acid (HA) in subjects with chronic low back pain (CLBP) associated with degenerative disc disease (DDD) through 36 months follow-up. (Source: The Spine Journal)
Source: The Spine Journal - October 8, 2020 Category: Orthopaedics Authors: Kasra Amirdelfan, Hyun Bae, Tory McJunkin, Michael DePalma, Kee Kim, William J. Beckworth, Gary Ghiselli, J. Scott Bainbridge, Randall Dryer, Timothy R. Deer, Roger D. Brown Tags: Clinical Study Source Type: research

Surgeon-level variance in achieving clinical improvement after lumbar decompression: the importance of adequate risk-adjustment
Patient-Reported Outcome Measurement Information System (PROMIS) scores are increasingly utilized in clinical care. However, it is unclear if PROMIS can discriminate surgeon performance on an individual level. (Source: The Spine Journal)
Source: The Spine Journal - October 8, 2020 Category: Orthopaedics Authors: Aditya V. Karhade, Rachel C. Sisodia, Christopher M. Bono, Harold A. Fogel, Stuart H. Hershman, Thomas D. Cha, Terence P. Doorly, James D. Kang, Joseph H. Schwab, Daniel G. Tobert Tags: Clinical Study Source Type: research

Use of Electromyography to Predict Likelihood of Recovery Following C5 Palsy after Posterior Cervical Spine Surgery
: C5 palsy affects approximately 5-10% of patients undergoing cervical spine surgery. It has a significant negative impact on patient quality-of-life outcomes and healthcare costs. While>80% of patients improve, some are left with persistent, debilitating deficits. Our objective was to examine if electrodiagnostic testing could be used to successfully identify patients likely to experience complete, partial, and no recovery. (Source: The Spine Journal)
Source: The Spine Journal - October 4, 2020 Category: Orthopaedics Authors: Daniel Lubelski, Zach Pennington, Ryan F. Planchard, Ahmet Hoke, Nicholas Theodore, Daniel M. Sciubba, Allan J. Belzberg Source Type: research

Risk Factors for Postoperative Ileus after Oblique Lateral Interbody Fusion: A Multivariate Analysis
Recently, oblique lateral interbody fusion (OLIF) has become a widely used, efficient surgical approach for various degenerative lumbar conditions, such as spinal stenosis, spondylolisthesis, and deformity [1-7]. Since OLIF utilizes the oblique ante-psoas corridor, approach-related complications that occur with other existing lumbar interbody fusion approaches such as injuries to major retroperitoneal vessels and peritoneal contents in anterior lumbar interbody fusion (ALIF) and proximal lower limb neurological deficits in direct lateral lumbar interbody fusion (LLIF), do not tend to occur with OLIF [2, 8]. (Source: The Spine Journal)
Source: The Spine Journal - October 4, 2020 Category: Orthopaedics Authors: Sung Cheol Park, Sam Yeol Chang, Sujung Mok, Hyoungmin Kim, Bong-Soon Chang, Choon-Ki Lee Tags: Clinical Study Source Type: research