Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research

18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research

Molecules, Vol. 28, Pages 5855: Research Progress on Structural Modification of Effective Antitumor Active Ingredients in Licorice
This article reviews the structural modification of effective antitumor active ingredients in licorice, thus providing a theoretical basis for further investigation of licorice and the development of new antitumor drugs. (Source: Molecules)
Source: Molecules - August 3, 2023 Category: Chemistry Authors: Chi Liu Qing Ma Guangfei Gong Fengyan Su Tags: Review Source Type: research

Improves immunological and histological alterations associated with Polycystic ovarian syndrome in DHEA -induced mice by Licorice extract
This study investigated the anti-inflammatory effect of licorice extract on PCOS. After induction of PCOS by subcutaneous injection (SC) of dehydroepiandrosterone (DHEA) (60  mg/kg) in BALB/C mice for 21 days, the mice were treated with licorice extract (50 mg/kg) for 21 days. At the end of experimental procedures, ovarian morphology, blood antioxidant capacity, nitric oxide (NO), the abundance of Treg cells, and expression of matrix metalloproteinase-9 (MMP-9), tra nsforming growth factor-ß (TGF-ß), cyclooxygenase-2 genes (COX-2), and tumor necrosis factor-alpha (TNF-α) were measured. The estrus cycle returned to n...
Source: Comparative Clinical Pathology - July 26, 2023 Category: Pathology Source Type: research

Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells
CONCLUSION: ISL induced ferroptosis in GBC mainly by activating p62-Keap1-Nrf2-HMOX1 signaling pathway and down-regulating GPX4 in vitro and in vivo. This evidence may provide a new direction for the treatment of GBC.PMID:37488674 | DOI:10.1097/CM9.0000000000002675 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - July 24, 2023 Category: General Medicine Authors: Zeyu Wang Weijian Li Xue Wang Qin Zhu Liguo Liu Shimei Qiu Lu Zou Ke Liu Guoqiang Li Huijie Miao Yang Yang Chengkai Jiang Yong Liu Rong Shao Xu'an Wang Yingbin Liu Source Type: research

Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells
CONCLUSION: ISL induced ferroptosis in GBC mainly by activating p62-Keap1-Nrf2-HMOX1 signaling pathway and down-regulating GPX4 in vitro and in vivo. This evidence may provide a new direction for the treatment of GBC.PMID:37488674 | DOI:10.1097/CM9.0000000000002675 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - July 24, 2023 Category: General Medicine Authors: Zeyu Wang Weijian Li Xue Wang Qin Zhu Liguo Liu Shimei Qiu Lu Zou Ke Liu Guoqiang Li Huijie Miao Yang Yang Chengkai Jiang Yong Liu Rong Shao Xu'an Wang Yingbin Liu Source Type: research

Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells
CONCLUSION: ISL induced ferroptosis in GBC mainly by activating p62-Keap1-Nrf2-HMOX1 signaling pathway and down-regulating GPX4 in vitro and in vivo. This evidence may provide a new direction for the treatment of GBC.PMID:37488674 | DOI:10.1097/CM9.0000000000002675 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - July 24, 2023 Category: General Medicine Authors: Zeyu Wang Weijian Li Xue Wang Qin Zhu Liguo Liu Shimei Qiu Lu Zou Ke Liu Guoqiang Li Huijie Miao Yang Yang Chengkai Jiang Yong Liu Rong Shao Xu'an Wang Yingbin Liu Source Type: research

Enrichment and qualitative analysis of flavonoid glycosides from the aerial parts of < em > Glycyrrhiza uralensis < /em > Fisch
This study provides not only an approach to enrich flavonoid glycosides but also a methodology for quickly determining the relevant bioactive components in the aerial parts of G. uralensis Fisch.PMID:37431638 | DOI:10.1080/14786419.2023.2226296 (Source: Natural Product Research)
Source: Natural Product Research - July 11, 2023 Category: Biochemistry Authors: Guanhua Chang Haifan Liu Jie Cui Zilong Wang Wenquan Wang Junling Hou Source Type: research

Enrichment and qualitative analysis of flavonoid glycosides from the aerial parts of < em > Glycyrrhiza uralensis < /em > Fisch
This study provides not only an approach to enrich flavonoid glycosides but also a methodology for quickly determining the relevant bioactive components in the aerial parts of G. uralensis Fisch.PMID:37431638 | DOI:10.1080/14786419.2023.2226296 (Source: Natural Product Research)
Source: Natural Product Research - July 11, 2023 Category: Biochemistry Authors: Guanhua Chang Haifan Liu Jie Cui Zilong Wang Wenquan Wang Junling Hou Source Type: research