GSE223524 Breast cancer prevention with liquiritigenin
Contributors : Atieh Hajirahimkhan ; Caitlin Howell ; Elizabeth Bartom ; Huali Dong ; Daniel Lantvit ; Xiaoling Xuei ; Shao-Nong Chen ; Guido Pauli ; Judy Bolton ; Susan Clare ; Seema Khan ; Birgit DietzSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBreast cancer risk continues to increase post menopause. Anti-estrogen therapies are available to prevent postmenopausal breast cancer in high-risk women. However, their adverse effects have reduced acceptability and overall success in cancer prevention. Natural products such as hops (Humulus lupulus) and three pharmacopeial l...
Source: GEO: Gene Expression Omnibus - August 30, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Risk factors and drug discovery for cognitive impairment in type 2 diabetes mellitus using artificial intelligence interpretation and graph neural networks
ConclusionThe method based on Interpreting AI and GNN can identify the risk factors and potential drugs associated with T2DM-CI. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - August 25, 2023 Category: Endocrinology Source Type: research
Molecules, Vol. 28, Pages 6142: Glycyrrhiza glabra L. Extracts and Other Therapeutics against SARS-CoV-2 in Central Eurasia: Available but Overlooked
Conclusions: The synthetic, low-molecular-weight compound Cridanimod suppresses SARS-CoV-2 replication at notably low concentrations, and this drug is not toxic to cells at therapeutic concentrations. In contrast to its role as an inducer of interferons, Cridanimod is active in cells that have a genetic defect in interferon production, suggesting a different mechanism of action. Cridanimod is an attractive drug for inclusion in clinical trials against SARS-CoV-2 and, presumably, other coronaviruses. The extract from licorice shows low activity against SARS-CoV-2. At the same time, high doses of 2 g/kg of this plant extract...
Source: Molecules - August 19, 2023 Category: Chemistry Authors: Murat Zh. Zhurinov Alfira F. Miftakhova Viktoriya Keyer Zarina T. Shulgau Elena V. Solodova Maxat K. Kalykberdiyev Arlan Z. Abilmagzhanov Eldar T. Talgatov Sauyk Ait Alexandr V. Shustov Tags: Article Source Type: research
Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining
CONCLUSION: This analytical study of the medical cases of TCM treatment for lung cancer was performed using data mining techniques, and the out-of-set association rules between clinical symptoms and drugs were analyzed, including the understanding of lung cancer in TCM. Moreover, the essence of experience in drug use was gathered, providing significant scientific guidance for the clinical treatment of lung cancer.PMID:37545275 | DOI:10.3233/THC-230269 (Source: Technology and Health Care)
Source: Technology and Health Care - August 7, 2023 Category: Medical Devices Authors: Mei Hong Yi-Dong Zhao Too-Li Zhong Ming Lu Wen-Hao Sun Tian-Yuan Chen Nan Hong Yao Zhu Da-Hai Yu Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
18 β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3
CONCLUSION: 18β-GRA promotes the synthesis of autophagosomes and inhibits GC cell proliferation by regulating the miR-328-3p/STAT3 signaling pathway.PMID:37545635 | PMC:PMC10401664 | DOI:10.3748/wjg.v29.i27.4317 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - August 7, 2023 Category: Gastroenterology Authors: Yi Yang Yi Nan Yu-Hua Du Shi-Cong Huang Dou-Dou Lu Jun-Fei Zhang Xia Li Yan Chen Lei Zhang Ling Yuan Source Type: research
