Quality evaluation of natural monomer flavors for Chinese tobacco industry based on dual mode combined Fourier transform ion cyclotron resonance mass spectrometry and isotopic fine structures
CONCLUSIONS: The integration strategy established here can discover and quantify the chemical markers for improving the quality control standard of natural monomer flavor of licorice. It is expected that the strategy will be valuable for further quality control of other natural monomer flavors in Chinese tobacco industry.PMID:38644558 | DOI:10.1002/rcm.9748 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - April 22, 2024 Category: Chemistry Authors: Juncang Peng Yaling Fan Yuping He Yao Wang Yaqing Zhu Yu Fu Yonglin Shang Jia Yu Source Type: research

18- β-glycyrrhetinic acid-loaded polymeric nanoparticles attenuate cigarette smoke-induced markers of impaired antiviral response in vitro
This study explores the therapeutic potential of an advanced drug delivery system encapsulating 18-β-gly in poly lactic-co-glycolic acid (PLGA) nanoparticles in addressing the impaired antiviral immunity observed in smokers and COPD patients. Exposure of BCi-NS1.1 human bronchial epithelial cells to cigarette smoke extract (CSE) resulted in reduced expression of critical antiviral chemokines (IP-10, I-TAC, MIP-1α/1β), mimicking what happens in smokers and COPD patients. Treatment with 18-β-gly-PLGA nanoparticles partially restored the expression of these chemokines, demonstrating promising therapeutic impact. The nanop...
Source: Pathology, Research and Practice - April 11, 2024 Category: Pathology Authors: Gabriele De Rubis Keshav Raj Paudel Stewart Yeung Siddiq Mohamad Swathi Sudhakar Sachin Kumar Singh Gaurav Gupta Philip Michael Hansbro Dinesh Kumar Chellappan Brian Gregory George Oliver Kamal Dua Source Type: research

18- β-glycyrrhetinic acid-loaded polymeric nanoparticles attenuate cigarette smoke-induced markers of impaired antiviral response in vitro
This study explores the therapeutic potential of an advanced drug delivery system encapsulating 18-β-gly in poly lactic-co-glycolic acid (PLGA) nanoparticles in addressing the impaired antiviral immunity observed in smokers and COPD patients. Exposure of BCi-NS1.1 human bronchial epithelial cells to cigarette smoke extract (CSE) resulted in reduced expression of critical antiviral chemokines (IP-10, I-TAC, MIP-1α/1β), mimicking what happens in smokers and COPD patients. Treatment with 18-β-gly-PLGA nanoparticles partially restored the expression of these chemokines, demonstrating promising therapeutic impact. The nanop...
Source: Pathology, Research and Practice - April 11, 2024 Category: Pathology Authors: Gabriele De Rubis Keshav Raj Paudel Stewart Yeung Siddiq Mohamad Swathi Sudhakar Sachin Kumar Singh Gaurav Gupta Philip Michael Hansbro Dinesh Kumar Chellappan Brian Gregory George Oliver Kamal Dua Source Type: research

Integrative physiology and transcriptome reveal salt-tolerance differences between two licorice species: Ion transport, Casparian strip formation and flavonoids biosynthesis
Glycyrrhiza inflata Bat. and Glycyrrhiza uralensis Fisch. are both original plants of ‘Gan Cao’ in the Chinese Pharmacopoeia, and G. uralensis is currently the mainstream variety of licorice and has a long histor... (Source: BMC Plant Biology)
Source: BMC Plant Biology - April 11, 2024 Category: Biology Authors: Xin Li, Ying Xu, Jiade Zhang, Ke Xu, Xuerong Zheng, Jiafen Luo and Jiahui Lu Tags: Research Source Type: research

A Practical Algorithm Integrating Skin Care With Nonenergy and Injectable Dermatologic Procedures to Improve Patient Outcomes and Satisfaction
CONCLUSION: Nonenergy and injectable procedures combined with skin care or topical treatments may improve outcomes and patient satisfaction. Topical antioxidants and free radical quenchers can combat photodamage and may offer a safe alternative to topical hydroquinone.    J Drugs Dermatol. 2024;23(4):     doi:10.36849/JDD.7918.PMID:38564400 | DOI:10.36849/JDD.7918 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Authors: Edward Lain Anneke Andriessen Valeria Barreto Campos Sabrina Guillen Fabi Lisa Ginn Ariel Haus Valerie M Harvey Jean-Fran çois Tremblay Source Type: research