Investigation of the preparation, characterization, and whitening activity of glabridin and oxymatrine co-amorphous
CrystEngComm, 2023, Accepted Manuscript DOI: 10.1039/D3CE00807J, PaperPeiyi Liang, Yi Hu, Zhuxian Wang, Yinglin Guo, Hongkai Chen, Cuiping Jiang, Quanfu Zeng, Chunyan Shen, Yufan Wu, Li Liu, Yankui Yi, Hongxia Zhu, Zhijun Yang, Qiang Liu Glabridin (Gla) is a natural active ingredient extracted from licorice root with good whitening activity. However, its poor solubility limits its further application. Therefore, this study aimed to develop a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - CrystEngComm latest articles)
Source: RSC - CrystEngComm latest articles - September 26, 2023 Category: Chemistry Authors: Peiyi Liang Source Type: research

Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug design approach
Breast and lung cancer are two of the most lethal forms of cancer, responsible for a disproportionately high number of deaths worldwide. Both doctors and cancer patients express alarm about the rising incidence of the disease globally. Although targeted treatment has achieved enormous advancements, it is not without its drawbacks. Numerous medicines and chemotherapeutic drugs have been authorized by the FDA; nevertheless, they can be quite costly and often fall short of completely curing the condition. Therefore, this investigation has been conducted to identify a potential medication against breast and lung cancer through...
Source: Frontiers in Oncology - September 25, 2023 Category: Cancer & Oncology Source Type: research

Development and Optimization of Culture Medium for the Production of Glabridin by < em > Aspergillus eucalypticola < /em > : An Endophytic Fungus Isolated from < em > Glycyrrhiza glabra < /em > L. (Fabaceae)
Mycobiology. 2023 Jul 12;51(4):230-238. doi: 10.1080/12298093.2023.2225253. eCollection 2023.ABSTRACTGlabridin is a well-known active isoflavone found in the root of licorice (Glycyrrhiza glabra L.) that possess a wide range of biological activity. Plant cells, hairy roots, and fungal endophytes cultures are the most important alternative methods for plant resources conservation and sustainable production of natural compounds, which has received much attention in recent decades. In the present study, an efficient culture condition was optimized for the biomass accumulation and glabridin production from fungal endophyte Asp...
Source: Mycobiology - September 15, 2023 Category: Biology Authors: Parisa Bahadori Ganjabadi Mohsen Farzaneh Mohammad Hossein Mirjalili Source Type: research