Absorption, tissue distribution, and excretion of glycycoumarin, a major bioactive coumarin from Chinese licorice (Glycyrrhiza uralensis Fisch)
Licorice (Glycyrrhiza uralensis Fisch) is a natural plant resource widely used as a food and herbal medication in China. Glycycoumarin (GCM) is a major coumarin in licorice that possesses several biological activities. However, little is known about its pharmacokinetic profile. The present study aimed to describe the oral absorption, tissue distribution, and excretion of GCM in rats. Free (parent drug) and/or total (parent drug plus the glucuronidated metabolite) GCM in biological samples was quantified before and after the hydrolysis reaction with β-glucuronidase using a reliable LC-MS/MS method. The results indicated th...
Source: Frontiers in Pharmacology - July 7, 2023 Category: Drugs & Pharmacology Source Type: research
Glycyrrhiza polysaccharides inhibits PRRSV replication
Glycyrrhiza polysaccharide (GCP) is a natural plant active polysaccharide extracted from traditional Chinese medicine licorice. In this research, we studied the antiviral activity of glycyrrhiza polysaccharide... (Source: Virology Journal)
Source: Virology Journal - July 5, 2023 Category: Virology Authors: Youbing Yang, Yongjian Liu, Ran Lou, Ying Lei, Gan Li, Zhiqian Xu and Xiangbin You Tags: Research Source Type: research
Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation
Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):1-6. doi: 10.14715/cmb/2023.69.4.1.ABSTRACTNowadays, medicinal plants are used to overcome the side effects of prescription drugs in modern medicine. Glycyrrhizic acid (GA) derived from the root of the licorice plant is one of the plant compounds whose effectiveness has been confirmed in the treatment of inflammatory bowel disorders (IBD). Liposome thin film hydration method was used to synthesize chitosan-coated liposomes containing GA. In the present study, chitosan-coated liposome was characterized by dynamic light scattering (DLS), zeta potential, scanning electron micr...
Source: Cellular and Molecular Biology - June 17, 2023 Category: Molecular Biology Authors: Tahereh Naseriyeh Danial Kahrizi Hosna Alvandi Faranak Aghaz Ghazal Nowroozi Alireza Shamsi Omid Hosseini Elham Arkan Source Type: research
Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation
Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):1-6. doi: 10.14715/cmb/2023.69.4.1.ABSTRACTNowadays, medicinal plants are used to overcome the side effects of prescription drugs in modern medicine. Glycyrrhizic acid (GA) derived from the root of the licorice plant is one of the plant compounds whose effectiveness has been confirmed in the treatment of inflammatory bowel disorders (IBD). Liposome thin film hydration method was used to synthesize chitosan-coated liposomes containing GA. In the present study, chitosan-coated liposome was characterized by dynamic light scattering (DLS), zeta potential, scanning electron micr...
Source: Mol Biol Cell - June 17, 2023 Category: Molecular Biology Authors: Tahereh Naseriyeh Danial Kahrizi Hosna Alvandi Faranak Aghaz Ghazal Nowroozi Alireza Shamsi Omid Hosseini Elham Arkan Source Type: research
Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation
Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):1-6. doi: 10.14715/cmb/2023.69.4.1.ABSTRACTNowadays, medicinal plants are used to overcome the side effects of prescription drugs in modern medicine. Glycyrrhizic acid (GA) derived from the root of the licorice plant is one of the plant compounds whose effectiveness has been confirmed in the treatment of inflammatory bowel disorders (IBD). Liposome thin film hydration method was used to synthesize chitosan-coated liposomes containing GA. In the present study, chitosan-coated liposome was characterized by dynamic light scattering (DLS), zeta potential, scanning electron micr...
Source: Cellular and Molecular Biology - June 17, 2023 Category: Molecular Biology Authors: Tahereh Naseriyeh Danial Kahrizi Hosna Alvandi Faranak Aghaz Ghazal Nowroozi Alireza Shamsi Omid Hosseini Elham Arkan Source Type: research
Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation
Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):1-6. doi: 10.14715/cmb/2023.69.4.1.ABSTRACTNowadays, medicinal plants are used to overcome the side effects of prescription drugs in modern medicine. Glycyrrhizic acid (GA) derived from the root of the licorice plant is one of the plant compounds whose effectiveness has been confirmed in the treatment of inflammatory bowel disorders (IBD). Liposome thin film hydration method was used to synthesize chitosan-coated liposomes containing GA. In the present study, chitosan-coated liposome was characterized by dynamic light scattering (DLS), zeta potential, scanning electron micr...
Source: Mol Biol Cell - June 17, 2023 Category: Molecular Biology Authors: Tahereh Naseriyeh Danial Kahrizi Hosna Alvandi Faranak Aghaz Ghazal Nowroozi Alireza Shamsi Omid Hosseini Elham Arkan Source Type: research
Glycyrrhizic acid delivery system Chitosan-coated liposome as an adhesive anti-inflammation
Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):1-6. doi: 10.14715/cmb/2023.69.4.1.ABSTRACTNowadays, medicinal plants are used to overcome the side effects of prescription drugs in modern medicine. Glycyrrhizic acid (GA) derived from the root of the licorice plant is one of the plant compounds whose effectiveness has been confirmed in the treatment of inflammatory bowel disorders (IBD). Liposome thin film hydration method was used to synthesize chitosan-coated liposomes containing GA. In the present study, chitosan-coated liposome was characterized by dynamic light scattering (DLS), zeta potential, scanning electron micr...
Source: Cellular and Molecular Biology - June 17, 2023 Category: Molecular Biology Authors: Tahereh Naseriyeh Danial Kahrizi Hosna Alvandi Faranak Aghaz Ghazal Nowroozi Alireza Shamsi Omid Hosseini Elham Arkan Source Type: research
