Comparison between N 13 NH 3 -PET and 99m Tc-Tetrofosmin-CZT SPECT in the evaluation of absolute myocardial blood flow and flow reserve
ConclusionsOur data show a reasonable correlation between MBF and MFR measured by N13NH3-PET and99mTc-Tetrofosmin-CZT SPECT. NAC-CZT overestimates MBF. AC is recommended when using CZT for measuring MBF. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - November 13, 2019 Category: Nuclear Medicine Source Type: research

Myocardial Perfusion SPECT 2018 in Germany: Results of the 8th Survey.
CONCLUSION:  The 2018 MPS survey reveals a high-grade adherence of routine MPS practice to current guidelines. The positive development in MPS performance and MPS numbers observed since 2012 remains ongoing. PMID: 31648359 [PubMed - as supplied by publisher] (Source: Nuklearmedizin)
Source: Nuklearmedizin - October 23, 2019 Category: Radiology Authors: Lindner O, Burchert W, Buechel R, Schäfer WM, Im Namen der Arbeitsgemeinschaft „Kardiovaskuläre Nuklearmedizin“ der Deutschen Gesellschaft für Nuklearmedizin und der AG20 „Nuklearkardiologische Diagnostik“ der Deutschen Gesellschaft für Kardi Tags: Nuklearmedizin Source Type: research

Daily Caffeine Consumption is Associated with Decreased Incidence of Symptoms and Hemodynamic Changes During Pharmacologic Stress with Regadenoson.
Conclusion: Caffeine consumers receiving regadenoson stress MPI was very common, and use of regadenoson for MPI in caffeine consumers is safe and associated with lower incidence of certain symptoms compared to non-caffeine consumers. Specifically, caffeine intake was associated with less aminophylline use and chest pain. PMID: 31604901 [PubMed - as supplied by publisher] (Source: Journal of Nuclear Medicine Technology)
Source: Journal of Nuclear Medicine Technology - October 13, 2019 Category: Nuclear Medicine Tags: J Nucl Med Technol Source Type: research

Myocardial perfusion imaging with regadenoson stress in advanced lung disease
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - October 2, 2019 Category: Nuclear Medicine Source Type: research

Feasibility and accuracy of SPECT myocardial perfusion imaging in end-stage lung disease
ConclusionsSPECT-MPI using regadenoson is well tolerated in patients with ELD and can help to make decisions about coronary revascularization before lung transplant. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - August 18, 2019 Category: Nuclear Medicine Source Type: research

Regadenoson myocardial perfusion imaging predicts prognosis in patients with either left bundle branch block or a ventricular paced rhythm
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - August 4, 2019 Category: Nuclear Medicine Source Type: research

Regadenoson Stress Perfusion Cardiac Magnetic Resonance Imaging in Children with Kawasaki Disease and Coronary Artery Disease
Coronary artery (CA) stenosis and occlusion in convalescent Kawasaki disease (KD) is progressive and may result in myocardial infarction. The use of regadenoson, a strong selective CA vasodilator with low side effect profile, for stress cardiac magnetic resonance imaging (CMR) has not been studied in children with KD. The safety, feasibility, and diagnostic utility of regadenoson stress CMR was assessed in children with KD and CA abnormalities. A retrospective review of regadenoson stress CMR in children with convalescent KD was performed. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - July 15, 2019 Category: Cardiology Authors: Tam T. Doan, James C. Wilkinson, Robert W. Loar, Amol S. Pednekar, Prakash M. Masand, Cory V. Noel Source Type: research

Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients
ConclusionGBCA-enhanced CMR imaging demonstrates low AAE rates comparable to those of other body regions. AAE likelihood correlates with GBCA subtype, pharmacological stressor, and imaging indication. Intravenous fluid administration in patients with cardiac impairment might contribute to these findings.Key Points• Acute adverse event rates in cardiac magnetic resonance (CMR) imaging with gadolinium-based contrast agents (GBCAs) are low (0.36%), especially for severe adverse events (0.033%).• Mild and moderate adverse events are more frequent during stress CMR imaging.• Physiologic AAEs are more common than allergic ...
Source: European Radiology - June 7, 2019 Category: Radiology Source Type: research

Dobutamine Stress Cardiac Positron Emission Tomography: Coronary Flow Reserve and Physiologic Targets
This study brings into question whether traditional heart rate goals should be used in provocative stress testing with myocardial imaging, or whether other metrics such as the ratio of heart rate increase which align more closely with the increase in myocardial blood flow should be used. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Stewart, M., Bober, R. Tags: Cardiovascular Clinical Science: Advances in Clinical Utility of Myocardial Blood Flow Quantification Source Type: research

Comparison among 82Rb PET/CT myocardial flow reserve methods
Conclusions: Although 95% confidence limits between the 2 methods were large, they produced essentially similar global MFR values & characterized abnormal pts with essentially the same frequency. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Van Tosh, A., Cao, J. J., Votaw, J., Cooke, C., Palestro, C., Nichols, K. Tags: Cardiovascular Basic Science: Myocardial Perfusion and Flow Quantification Source Type: research

Prevalence of compromised 82Rb PET bolus injection integrity assessed by automated quality control algorithms
Conclusions: It is important to verify integrity of the injected 82Rb bolus in order to assure the quality of MFR computations performed as part of CAD pt evaluation. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Van Tosh, A., Cao, J. J., Votaw, J., Cooke, C., Palestro, C., Nichols, K. Tags: Cardiovascular Basic Science: Myocardial Perfusion and Flow Quantification Source Type: research

Regadenoson Associated Side Effect Reversal: Safety and Efficacy of IV Theophylline
Conclusions: During periods of drug shortages, IV theophylline is a reasonable alternative to aminophylline for reversal of regadenoson associated side-effect experienced during pharmacologic stress testing. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Raines, J., Shakowski, C., Page, R., Quaife, R. Tags: Cardiovascular Clinical Science: Improving Prognostication from Cardiac Nuclear Imaging Source Type: research

Assessment of coronary flow reserve by routine 99mTc-tetrofosmin SPECT: a new method.
Conclusions: Assessment of CFR is feasible with routine 99mTc-tetrofosmin, allowing to decrease the number of false negative SPECT. This method is easy to use on a routine basis, totally reproducible (automatic process ). There is no additional time or cost to the routine SPECT. Sensitivity and specificity are very good for CAD diagnosis. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: PHILIPPE, L., PRUNIER AESCH, C., EL YAAGOUBI, Y. Tags: Cardiovascular Clinical Science Posters Source Type: research

Chronic Caffeine Consumption is Associated with Lower Incidences of Symptoms and Hemodynamic Changes During Pharmacologic Stress with Regadenoson
Conclusions: Chronic caffeine intake prior to regadenoson stress MPI was very common, and abruptly stopping caffeine for MPI is safe and associated more with changes in symptoms rather than physiologic parameters. Indeed, chronic caffeine intake was associated with less aminophylline use and chest pain. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Posch, M., Kay, M., Harhash, A., Huang, J., Krupinski, E., Abidov, A., Kuo, P. Tags: Cardiovascular Clinical Science Posters Source Type: research

Handling and workflow guidelines for a novel 18F-PET Cardiology tracer, Flurpiridaz.
Conclusions: There are specific guidelines and protocols that need to be followed when handling Flurpiridaz. After observation and execution of the Flurpiridaz workflow, five main categories were identified. Within those categories, there are critical elements that need to be practiced when using Flurpiridaz for the assessment of myocardial perfusion. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Acuff, S., Shepple, B., Osborne, D. Tags: Tech Papers II: Cardiovascular Sciences Source Type: research