Evaluation of quantitative CMR perfusion imaging by comparison with simultaneous 15 O-water-PET
ConclusionThe correlation between simultaneous MBF measurements with DCE MRI and15O-water PET measured in an integrated PET-MRI was strong but the agreement was only moderate indicating that MRI-based quantitative MBF measurements is not ready for clinical introduction. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 16, 2019 Category: Nuclear Medicine Source Type: research

Complementary pre-operative risk assessment using coronary computed tomography angiography and nuclear myocardial perfusion imaging in non-cardiac surgery: A VISION-CTA sub-study
AbstractBackground The incremental value and optimal utilization of non-invasive testing for prediction of peri-operative cardiac events during non-cardiac surgery are not clear.MethodsA sub-study of VISION-CTA was performed using patients who underwent both coronary computed tomography angiography (CCTA) and nuclear myocardial perfusion imaging (MPI) as part of their pre-operative assessment. CCTA images were compared with MPI to determine the correlation between ischemia and obstructive coronary artery disease (CAD). Patients were followed post-operatively for 30  days and primary outcomes were all-cause death and...
Source: Journal of Nuclear Cardiology - July 15, 2019 Category: Nuclear Medicine Source Type: research

Selection of abstracts from the scientific sessions of The Society Of Nuclear Medicine and Molecular Imaging annual meeting Anaheim CA
AbstractThis mini-review highlights cardiovascular studies that were presented during the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2019 annual meeting in Anaheim, California. The aim is to provide the readers insight to noteworthy studies related to the fields of nuclear cardiology presented during the conference. Although cardiovascular applications of positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are not the primary focus of the SNMMI, several scientific teams working in this field presented their latest findings in Anaheim. While this review is directed to the...
Source: Journal of Nuclear Cardiology - July 15, 2019 Category: Nuclear Medicine Source Type: research

Severe myocardial ischemia in a patient with diabetes mellitus and left bundle branch block
We present the case of a 69-year-old woman with diabetes mellitus, left bundle branch block, and obesity who develops cardiogenic shock after undergoing myocardial perfusion imaging and diagnostic left heart catheterization, but prior to coronary revascularization. This case highlights the risk of cardiac decompensation awaiting surgery in patients with multivessel coronary artery disease. It also emphasizes the subtleties involved in imaging patients with diabetes mellitus and left bundle branch block, as well as the risk of developing complete heart block in the setting of ischemia with underlying conduction disease. (So...
Source: Journal of Nuclear Cardiology - July 15, 2019 Category: Nuclear Medicine Source Type: research

Diastolic assessment by CZT-SPECT: Could it be the next best thing for the detection of subclinical chemotherapy-induced cardiotoxicity?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 15, 2019 Category: Nuclear Medicine Source Type: research

Approaching perioperative cardiac risk: Forging new strategies against an old enemy
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 15, 2019 Category: Nuclear Medicine Source Type: research

Do we need a new definition for post-stress reduction in LVEF beyond the numerical values?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 10, 2019 Category: Nuclear Medicine Source Type: research

Myocardial perfusion reserve by using CZT: It ’s a long way to the top if you wanna standardize
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 9, 2019 Category: Nuclear Medicine Source Type: research

Refining practice: TID metrics for CZT systems
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 9, 2019 Category: Nuclear Medicine Source Type: research

Impact of International Atomic Energy Agency support to the development of nuclear cardiology in low-and-middle-income countries: Case of Latin America and the Caribbean
AbstractCardiovascular diseases (CVDs) are the leading cause of death in Latin America and the Caribbean (LAC) region as well as worldwide. Lifestyle, nutritional habits and the upsurge of obesity have contributed to the increase in the prevalence of CVDs in the region. The role of nuclear cardiology in the management of patients with CVDs is well established. Particularly, myocardial perfusion imaging is widely used in LAC countries and has been increasingly integrated into the healthcare systems in the region for the diagnosis of coronary artery disease, risk stratification and to guide patient management. In its role to...
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

Association between vertebral bone mineral density, myocardial perfusion, and long-term cardiovascular outcomes: A sex-specific analysis
AbstractBackgroundSexual dimorphism in the manifestation of coronary artery disease (CAD) has unleashed a call to reconsider cardiovascular risk assessment. Alterations of bone mineral density (BMD) have been associated with congestive heart failure and appear to be modified by sex. However, the sex-specific association between BMD, myocardial perfusion, and cardiovascular outcomes is currently unknown.Methods A total number of 491 patients (65.9  ± 10.7 years, 32.4% women) underwent13N-ammonia positron emission tomography/computed tomography for evaluation of CAD, and were tracked for major adv...
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

Beware! Some crucial information is left unattended on our myocardial perfusion scans!
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

ASNC ’s global impact: Transforming nuclear cardiology and making the world smaller
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

Cases from a busy nuclear cardiology laboratory
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

New series “Cases from a busy nuclear cardiology laboratory”
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 8, 2019 Category: Nuclear Medicine Source Type: research

Refining the role of gated SPECT for predicting clinical response to cardiac resynchronization therapy: Are we using the right tool at the wrong time?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 3, 2019 Category: Nuclear Medicine Source Type: research

Mexico-city does not look like Beverly-Hills: A multimodality and cardiac imager perspective!
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 3, 2019 Category: Nuclear Medicine Source Type: research

Left ventricular mechanical dyssynchrony in patients with chest pain and normal epicardial coronary arteries
AbstractBackgroundTo detect ischemia in patients with angina and normal coronaries frequently represents a complex diagnosis.MethodsTo investigate whether left ventricular mechanical dyssynchrony by phase analysis contributes in the evaluation of patients with chest pain and normal coronaries, gated-SPECT myocardial perfusion imaging (MPI) at rest and 30 minutes post-stress was performed in 218 patients with normal epicardial coronaries, who were divided into two groups: those with summed difference score (SDS) ≥ 4 (54 patients, Group 1), and those with SDS 
Source: Journal of Nuclear Cardiology - July 2, 2019 Category: Nuclear Medicine Source Type: research

Abstracts of Original Contributions ASNC2019 The 24th Annual Scientific Session of the American Society of Nuclear Cardiology
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 1, 2019 Category: Nuclear Medicine Source Type: research

Correction to: FMTVDM-TFM © ℗ : True quantification requires standardization of the tool being used to measure, with a known, unchanging standard to produce accurate, consistent and reproducible quantified measurements
The Editor wishes to clarify that the authors of the above named Letter provided ICMJE Conflict of Interest forms at the time of submission, and that the Journal omitted to include the resulting statement in the published Letter (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 1, 2019 Category: Nuclear Medicine Source Type: research

A quick glance at selected topics in this issue
Abstract“A quick glance at selected topics in this issue” aims to highlight contents of theJournal and provide a quick review to the readers. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 28, 2019 Category: Nuclear Medicine Source Type: research

Is the PPI responsible for that inferior MI?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 28, 2019 Category: Nuclear Medicine Source Type: research

Letters to the editor
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 28, 2019 Category: Nuclear Medicine Source Type: research

ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease
AbstractThis document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. The first document (J Am Coll Cardiol 2017;70:1647-1672) addresses the evaluation and use of multimodality imaging in the diagnosis ...
Source: Journal of Nuclear Cardiology - June 27, 2019 Category: Nuclear Medicine Source Type: research

Preparation is everything: The impact of a structured preparation protocol on cardiac 18 F-FDG PET imaging for cardiac sarcoidosis
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 27, 2019 Category: Nuclear Medicine Source Type: research

What is This Image? 2019: Image  2
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 26, 2019 Category: Nuclear Medicine Source Type: research

Characterization of a highly effective preparation for suppression of myocardial glucose utilization
AbstractBackgroundWith appropriate protocols, F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) can visualize myocardial inflammation. Optimal protocols and normative myocardial FDG uptake values are not well-established.MethodsWe evaluated 111 patients referred for inflammation cardiac FDG PET/CT. Patients followed a low-carbohydrate, high-fat diet for 36 hours before imaging and received unfractionated heparin. Glucose and fatty acid metabolism biomarkers were obtained. Mean blood pool and maximum myocardial uptake (SUVmean, SUVmax) were measured, avoiding areas of abnormal FDG uptak...
Source: Journal of Nuclear Cardiology - June 24, 2019 Category: Nuclear Medicine Source Type: research

JNC Awards: In recognition of Frans Wackers, Raymond Gibbons and William Strauss
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 24, 2019 Category: Nuclear Medicine Source Type: research

Mechanisms of cardiac resynchronization therapy: Inching closer to the truth
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 21, 2019 Category: Nuclear Medicine Source Type: research

Quantification of myocardial flow reserve using a gamma camera with solid-state cadmium-zinc-telluride detectors: Relation to angiographic coronary artery disease
In this study, we aimed to evaluate the feasibility and accuracy of MFR quantification using a CZT camera compared to coronary angiography.MethodsForty-one participants referred for coronary angiography underwent a rest/stress one-day myocardial perfusion imaging protocol using a CZT gamma camera. Rest and stress dynamic phases were followed by acquisition of traditional perfusion images and time-activity curves were generated. Angiographic and perfusion results were compared to MFR.ResultsPatients with abnormal perfusion presented reduced MFR (2.01 [1.48-2.77] vs. 2.94 [2.38-3.64],P = 0.002), and reduced str...
Source: Journal of Nuclear Cardiology - June 20, 2019 Category: Nuclear Medicine Source Type: research

Head-to-head comparison of diagnostic accuracy of stress-only myocardial perfusion imaging with conventional and cadmium-zinc telluride single-photon emission computed tomography in women with suspected coronary artery disease
AbstractBackgroundBreast attenuation may impact the diagnostic accuracy of stress myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT). We compared the performance of conventional (C)-SPECT and cadmium-zinc-telluride (CZT)-SPECT systems in women with low-intermediate likelihood of coronary artery disease (CAD).Methods and ResultsA total of 109 consecutive women underwent stress-optional rest MPI by both C-SPECT and CZT-SPECT. In the overall study population, a weak albeit significant correlation between total perfusion defect (TPD) measured by C-SPECT and CZT-SPECT was observed (r = 0.38,P
Source: Journal of Nuclear Cardiology - June 20, 2019 Category: Nuclear Medicine Source Type: research

Anderson-Fabry disease: Worthy to in-SPECT the nerves?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 19, 2019 Category: Nuclear Medicine Source Type: research

Imaging of cardiac amyloidosis: Will this become a unique application for dual-isotope imaging?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 18, 2019 Category: Nuclear Medicine Source Type: research

Quantitative assessment of tricuspid regurgitation using right and left ventricular stroke volumes obtained from tomographic equilibrium radionuclide ventriculography
AbstractBackgroundQuantitative assessment of valve regurgitation using volumetric method by comparing right and left ventricular stroke volumes is still under investigations.AimsTo investigate the accuracy of tomographic equilibrium radionuclide ventriculography (t-ERV) for the quantification of tricuspid regurgitation (TR).Methods and ResultsSixty-one patients (44 men; mean age 59 ± 12 years) who underwent both t-ERV and transthoracic echocardiography (TTE) studies within 2 weeks for right ventricular systolic function assessment were eligible for inclusion. A sub-group of 22 patients underwent both t-ERV and CMR. ...
Source: Journal of Nuclear Cardiology - June 14, 2019 Category: Nuclear Medicine Source Type: research

Non-alcoholic fatty liver disease and coronary atherosclerosis-does myocardial glucose metabolism provide the missing link?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 14, 2019 Category: Nuclear Medicine Source Type: research

Feasibility of somatostatin receptor-targeted imaging for detection of myocardial inflammation: A pilot study
ConclusionOur preliminary data suggest that, compared to FDG imaging, somatostatin receptor-targeted imaging may be less sensitive for the detection of myocardial inflammation, but comparable for detecting extra-cardiac inflammation. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 13, 2019 Category: Nuclear Medicine Source Type: research

Recommendations for 18 F-fluorodeoxyglucose positron emission tomography imaging for diagnosis of cardiac sarcoidosis —2018 update: Japanese Society of Nuclear Cardiology recommendations
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 13, 2019 Category: Nuclear Medicine Source Type: research

Challenges and opportunities for nuclear cardiology
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 13, 2019 Category: Nuclear Medicine Source Type: research

Hybrid positron emission tomography-Magnetic resonance imaging for cardiac sarcoid
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 11, 2019 Category: Nuclear Medicine Source Type: research

A new era of imaging for diagnosis and management of cardiac sarcoidosis: Hybrid cardiac magnetic resonance imaging and positron emission tomography
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 7, 2019 Category: Nuclear Medicine Source Type: research

MPI in the era of CZT cameras: Absolute numbers are still better than relative figures
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 7, 2019 Category: Nuclear Medicine Source Type: research

Nuclear cardiology in the literature: A selection of recent, original research papers
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 7, 2019 Category: Nuclear Medicine Source Type: research

The Newer, the Better; and May Be Not Good Enough?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 7, 2019 Category: Nuclear Medicine Source Type: research

Fractional flow reserve as the standard of reference: All that glistens is not gold
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 7, 2019 Category: Nuclear Medicine Source Type: research

Simultaneous Tc-99m PYP/Tl-201 dual-isotope SPECT myocardial imaging in patients with suspected cardiac amyloidosis
AbstractIntroductionAssessment of myocardial uptake of Tc-99m-pyrophosphate (Tc-99m PYP) is pivotal in distinguishing transthyretin-associated cardiac amyloidosis (ATTR) from light chain amyloid (AL). It is often difficult to differentiate myocardial uptake from blood pool radioactivity with planar imaging or SPECT. We studied whether simultaneous dual-isotope Tc-99m PYP/Tl-201 SPECT improves assessment of Tc-99m PYP uptake compared to single-isotope SPECT.MethodsSimultaneous Tc-99m PYP/Tl-201 dual-isotope SPECT was acquired in 112 patients studied for possible cardiac amyloidosis. Visual interpretation was performed by tw...
Source: Journal of Nuclear Cardiology - June 6, 2019 Category: Nuclear Medicine Source Type: research

What is this image? 2019: Image  1 result
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 6, 2019 Category: Nuclear Medicine Source Type: research

Mechanical dyssynchrony & amp; CRT: Is it time for guideline updates?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 4, 2019 Category: Nuclear Medicine Source Type: research

18 F-FDG PET/CT now endorsed by guidelines across all types of CIED infection: Evidence limited but growing
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - May 15, 2019 Category: Nuclear Medicine Source Type: research

Myocardial Creep: we can now look it in the eye without framewise PET-CT registration for myocardial blood flow quantification
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - May 15, 2019 Category: Nuclear Medicine Source Type: research

Focal reduction in left ventricular 123 I-metaiodobenzylguanidine uptake and impairment in systolic function in patients with Anderson-Fabry disease
AbstractBackgroundAbnormalities of cardiac sympathetic innervation have been demonstrated in Anderson-Fabry disease (AFD). We aimed to investigate the relationship between regional left ventricular (LV) denervation and regional function abnormalities.MethodsTwenty-four AFD patients (43.7  ± 12.8 years) were studied by123I-metaiodobenzylguanidine (MIBG) cardiac imaging and speckle-tracking echocardiography. Segmental tracer uptake was estimated according to 0 to 4 score, and total defect score (TDS) was calculated for each patient.ResultsSegmental longitudinal strain worsened as MIBG uptake score increa...
Source: Journal of Nuclear Cardiology - May 13, 2019 Category: Nuclear Medicine Source Type: research