Log in to search using one of your social media accounts:

 

What is the value of motion and thickening in gated myocardial perfusion SPECT?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 23, 2018 Category: Nuclear Medicine Source Type: research

Isolated cardiac amyloidosis. Utility of bone seeking tracers scintigraphy in differentiating the subtype of amyloid: A case report
ConclusionNon-invasive tests for the detection of cardiac amyloidosis, like myocardial scintigraphy with bone seeking tracers, can play a major role in the diagnosis progression and therapeutic management of patients with cardiac amyloidosis. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 23, 2018 Category: Nuclear Medicine Source Type: research

Analogies and disparities among scintigraphic bone tracers in the diagnosis of cardiac and non-cardiac ATTR amyloidosis
AbstractIn this issue of JNC, BW Spery and Coll report a retrospective analysis of 57 patients with transthyretin-related amyloidosis (ATTR) in an advanced phase of the disease who underwent 99mTechnetium-pyrophosphate (99mTcPYP) scintigraphy. Although relatively small and “negative,” the study is relevant since it broadens our knowledge on the uptake of “bone tracers” in ATTR and contributes to understand the limitations of the clinical use of scintigraphy in this disease. The paper raises, directly or indirectly, at least three questions: To what extent are the different bone tracers interchangeab...
Source: Journal of Nuclear Cardiology - February 22, 2018 Category: Nuclear Medicine Source Type: research

Evolving, innovating, and revolutionary changes in cardiovascular imaging: We ’ve only just begun!
AbstractIn this review, we highlight the need for innovation and creativity to reinvent the field of nuclear cardiology. Revolutionary ideas brought forth today are needed to create greater value in patient care and highlight the need for more contemporary evidence supporting the use of nuclear cardiology practices. We put forth discussions on the need for disruptive innovation in imaging-guided care that places the imager as a central force in care coordination. Value-based nuclear cardiology is defined as care that is both efficient and effective. Novel testing strategies that defer testing in lower risk patients are exa...
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

Technical aspects of cardiac PET/MRI
This article describes several technical points, including patient preparation, MR attenuation correction, parallel acquisition of PET with MRI, clinical aspects, and image quality control. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

Adverse effects associated with regadenoson myocardial perfusion imaging
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

Cardiac adrenergic neuronal activity, sleep apnea, and potential therapeutic role of nocturnal ventilatory assistance in patients with heart failure
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

ASNC President ’s Message
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

The long way to defeating Chagas cardiomyopathy
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2018 Category: Nuclear Medicine Source Type: research

Repeatable and reproducible measurements of myocardial oxidative metabolism, blood flow and external efficiency using 11 C-acetate PET
This study evaluates the repeatability and reproducibility of11C-acetate positron emission tomography (PET) imaging of oxidative metabolism.Methods and resultsDynamic11C-acetate PET scans were performed at baseline and followup (47  ± 22 days apart) in 20 patients with stable HF with reduced ejection fraction. Two observers blinded to patients’ clinical data used FlowQuant® to evaluate test –retest repeatability, as well as intra- and inter-observer reproducibility of11C-acetate tracer uptake and clearance rates, for the measurement of myocardial oxygen consumption (MVO2), myocardial e...
Source: Journal of Nuclear Cardiology - February 16, 2018 Category: Nuclear Medicine Source Type: research

Tight software, methodological/physiological variation, less so
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 16, 2018 Category: Nuclear Medicine Source Type: research

A troubled marriage: When electrical and mechanical dyssynchrony don ’t go along
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 14, 2018 Category: Nuclear Medicine Source Type: research

Bridging the Atlantic gap in clinical guidelines for non-ST-elevation acute coronary syndromes
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 12, 2018 Category: Nuclear Medicine Source Type: research

More or less appropriate: The new rule of law for cardiac imaging
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 12, 2018 Category: Nuclear Medicine Source Type: research

The search for water: Is it so easy to diagnose acute myocarditis?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 12, 2018 Category: Nuclear Medicine Source Type: research

A case of longitudinal care of a patient with cardiac sarcoidosis
We present the case of a 36-year-old man known to have sarcoidosis in which a variety of imaging modalities not only assisted in the diagnosis of cardiac sarcoidosis, but also played a key role in the monitoring of disease activity and response to therapy. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 8, 2018 Category: Nuclear Medicine Source Type: research

Relationships between electrical and mechanical dyssynchrony in patients with left bundle branch block and healthy controls
In this study, we characterized and analyzed electrical and mechanical dyssynchrony in patient with left bundle branch block (LBBB) and healthy controls.MethodsMyocardial perfusion imaging (MPI) data from 994 patients were analyzed. Forty-three patient fulfilled criteria for LBBB and 24 for controls. Electrical activation was characterized with vector electrocardiography (VECG) and LV function including mechanical dyssynchrony with ECG-gated MPI phase analysis.ResultsQRS duration (QRSd;r = 0.69,P 
Source: Journal of Nuclear Cardiology - February 8, 2018 Category: Nuclear Medicine Source Type: research

Vascular age for predicting cardiovascular risk: A novel clinical marker or just a mathematical permutation
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 8, 2018 Category: Nuclear Medicine Source Type: research

Case Presentation Commentary on “A case of longitudinal care of a patient with cardiac sarcoidosis”
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 8, 2018 Category: Nuclear Medicine Source Type: research

Correction to: Comparison of two software systems for quantification of myocardial blood flow in patients with hypertrophic cardiomyopathy
This study was partly funded by NIH RO1 HL092985.” The last/corresponding author is incorrectly listed on the first page of the published article: The correct name isAbraham MR. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 8, 2018 Category: Nuclear Medicine Source Type: research

Summed thickening score by myocardial perfusion imaging: A risk factor of left ventricular remodeling in patients with  myocardial infarction
ConclusionsLV remodeling in old MI patients is more extensive and severe than that in subacute MI patients. LV wall thickening abnormalities as expressed by STS and the proportion of segments with reduced wall thickening in segments with normal perfusion are the independent risk factors of LV remodeling in MI patients. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

A quick glance at selected topics in this issue
AbstractA quick glance at selected topics in this issue aims to highlight contents of theJournal and provide a quick review to the readers. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Testing our tests: Do clinical studies of diagnostic performance truly inform patient management?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Development of an inflammation imaging tracer, 111 In-DOTA-DAPTA, targeting chemokine receptor CCR5 and preliminary evaluation in an ApoE −/− atherosclerosis mouse model
Conclusion111In-DOTA-DAPTA, specifically targeting chemokine receptor CCR5, is a potential SPECT agent for imaging inflammation in atherosclerosis. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Cardiovascular disease in the literature: A selection of recent original research papers
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Myocardial perfusion imaging prior to coronary revascularization: From risk stratification to procedure guidance
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Radiopharmaceuticals for cardiac imaging: Current status and future trends
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Arterial inflammation in young patients with human immunodeficiency virus infection: A cross-sectional study using F-18 FDG PET/CT
AbstractBackgroundHIV infection is associated with the risk of development of atherosclerosis at a younger age. We compared arterial inflammation in HIV-infected and HIV-uninfected patients with otherwise low-risk factors for cardiovascular disease (CVD) using FDG PET/CT.Methods242 patients aged 18 –40 years with low-risk factors for CVD consisting of 121 HIV-infected patients and 121 HIV-uninfected age- and gender-matched controls were studied, mean age = 34.95 ± 5.46 years. We calculated and compared the target-to-background ratio of FDG uptake in ascending aorta of HIV-infected and n on-...
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Provocative testing for low-risk chest pain patients, must we continue?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Future growth and success of nuclear cardiology
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

What is This Image? 2018: Image 5 Result
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Comparison of the AHA/ACC vs ESC guidelines for management of patients with non-ST-elevation acute coronary syndromes: Are the differences clinically different?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 7, 2018 Category: Nuclear Medicine Source Type: research

Nuclear cardiology in the literature: A selection of recent, original research papers
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 6, 2018 Category: Nuclear Medicine Source Type: research

Refining risk in diabetes and CAD with SPECT MPI: New insights and future challenges
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 5, 2018 Category: Nuclear Medicine Source Type: research

Multimodality imaging: Bird ’s eye view from The American College of Cardiology Annual Scientific Meeting 2017, Washington DC March 17 to 19, 2017
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 30, 2018 Category: Nuclear Medicine Source Type: research

Announcement: New initiative ‘case presentation corner’
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 30, 2018 Category: Nuclear Medicine Source Type: research

Utilization of stress testing for low-risk patients with chest discomfort in the emergency department
ConclusionThese data suggest a very low yield of detecting clinically significant coronary disease with stress testing low-risk patients with chest discomfort in emergency department chest pain units. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 26, 2018 Category: Nuclear Medicine Source Type: research

Correction to: Radiopharmaceutical tracers for cardiac imaging
AbstractRegrettably the original version of the above article contained errors in the three chemical structures presented in the ‘Atherosclerosis imaging’ section of Table 5, namely:99mTc annexin V,68Ga DOTATATE, and64Cu DOTATATE; the chemical structures have been corrected in Table presented here. In addition, the radiopharmaceutical for isotope67Ga has been corrected to67Ga citrate, and many of the radiopharmaceuticals presented at the end of the table have been corrected. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 24, 2018 Category: Nuclear Medicine Source Type: research

Multi-modality imaging: Bird ’s eye view from the 2017 American Heart Association Scientific Sessions
AbstractThis review summarizes key imaging studies that were presented in the American Heart Association Scientific Sessions 2017 related to the fields of nuclear cardiology, cardiac computed tomography, cardiac magnetic resonance, and echocardiography. The aim of this bird ’s eye view is to inform readers about multiple studies reported at the meeting from these different imaging modalities. While such a review is most useful for those that did not attend the conference, we find that a general overview may also be useful to those that did since it is often difficult to get exposure to many abstracts at large meeting...
Source: Journal of Nuclear Cardiology - January 23, 2018 Category: Nuclear Medicine Source Type: research

Detrimental effects of nitroglycerin use during regadenoson vasodilator stress testing: A cautionary tale
AbstractVasodilator agents such as adenosine and regadenoson are commonly used pharmacologic stressors to assess for ischemia in patients undergoing myocardial perfusion studies. The recommended reversal agent for this mode of stress is aminophylline, although nitroglycerin is commonly administered as an attempt to reverse the symptoms or electrocardiographic (EKG) changes during the stress test. We demonstrate through two cases that incorrect administration of nitroglycerin can induce hypotension and worsen coronary steal, whereas appropriate administration of aminophylline can reverse the effects of pharmacologic vasodil...
Source: Journal of Nuclear Cardiology - January 23, 2018 Category: Nuclear Medicine Source Type: research

Comparison of two software systems for quantification of myocardial blood flow in patients with  hypertrophic cardiomyopathy
ConclusionsAnatomic characteristics specific to HCM hearts contribute to lower correlations between MBF/MFR values obtained by PMod and QPET, compared with non-HCM patients. These differences indicate that PMod and QPET cannot be used interchangeably for MBF/MFR analyses in HCM patients. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 22, 2018 Category: Nuclear Medicine Source Type: research

Molecular imaging of calcific aortic valve disease
AbstractCalcific aortic valve disease (CAVD) can progress to symptomatic aortic stenosis in a subset of patients. The severity of aortic stenosis and the extent of valvular calcification can be evaluated readily by echocardiography, CT, and MRI using well-established imaging protocols. However, these techniques fail to address optimally other important aspects of CAVD, including the propensity for disease progression, risk of complications in asymptomatic patients, and the effect of therapeutic interventions on valvular biology. These gaps may be addressed by molecular imaging targeted at key biological processes such as i...
Source: Journal of Nuclear Cardiology - January 22, 2018 Category: Nuclear Medicine Source Type: research

Coronary vascular age: An alternate means for predicting stress-induced myocardial ischemia in patients with suspected coronary artery disease
AbstractBackgroundCoronary artery calcium (CAC) can be used to estimate vascular age in adults, providing a convenient transformation of CAC from Agatston units into a year ’s scale. We investigated the role of coronary vascular age in predicting stress-induced myocardial ischemia in subjects with suspected coronary artery disease (CAD).MethodsA total of 717 subjects referred to CAC scoring and82Rb PET/CT stress-rest myocardial perfusion imaging for suspected CAD were studied. CAC score was measured according to the Agatston method and coronary vascular age by equating estimated CAD risk for chronological age and CAC...
Source: Journal of Nuclear Cardiology - January 22, 2018 Category: Nuclear Medicine Source Type: research

Is left ventricular systolic index the new kid in the block?
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 22, 2018 Category: Nuclear Medicine Source Type: research

Rescued diagnostic quality by motion correction of dynamic cardiac positron emission tomography (PET) perfusion images
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 22, 2018 Category: Nuclear Medicine Source Type: research

Quantification of myocardial blood flow and myocardial flow reserve with SPECT imaging technique
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 19, 2018 Category: Nuclear Medicine Source Type: research

Impact of renin –angiotensin–aldosterone system polymorphisms on myocardial perfusion: Correlations with myocardial single photon emission computed tomography-derived parameters
ConclusionsAmong the polymorphisms investigated,ACE D allele had the strongest association with abnormal myocardial perfusion. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 17, 2018 Category: Nuclear Medicine Source Type: research

Reliability of the 123 I- m IBG heart/mediastinum ratio: Results of a multicenter test –retest reproducibility study
This study assessed the test–retest reproducibility of the H/M ratio in such patients. 47 subjects with class II-III systolic heart failure and LVEF ≤ 35% were tested at two time intervals separated by 5 to 14 days. Subjects were imaged twice on the same camera using the same radi onuclide dose. Images were sent to a core analysis lab, where three nuclear technologists independently determined the H/M ratios. The primary endpoint was test–retest H/M ratio reproducibility calculated as the absolute difference in mean value determined by the three readers. Mean subject age wa s 65 ±&...
Source: Journal of Nuclear Cardiology - January 17, 2018 Category: Nuclear Medicine Source Type: research

Non-cardiac uptake of technetium-99m pyrophosphate in transthyretin cardiac amyloidosis
AbstractBackgroundTechnetium-based bone scintigraphy is rapidly becoming the most common non-invasive imaging tool in the diagnosis of Transthyretin cardiac amyloidosis (ATTR). Skeletal muscle uptake has been described with technetium-99m-3,3-diphosphono-1,2-propanodicarboxylic acid (TcDPD), and may account for masking of bony uptake. We sought to investigate skeletal muscle uptake of technetium-99m-pyrophosphate (TcPYP) in patients with ATTR.Methods and ResultsThis was a retrospective analysis of 57 patients diagnosed with ATTR who underwent TcPYP scintigraphy. Cardiac uptake was assessed on whole-body planar imaging usin...
Source: Journal of Nuclear Cardiology - January 17, 2018 Category: Nuclear Medicine Source Type: research

The impact of patient-to-detector distance on LV volumes and TID index on SPECT myocardial perfusion imaging: Emphasis on consistent patient-detector positioning in stress and rest phases
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - January 17, 2018 Category: Nuclear Medicine Source Type: research