Is aminophylline injection the best practice as a reversal agent in nuclear cardiac stress testing?
Conclusions: The majority of hospitals reported pharmacologic stress testing to be more common than exercise testing and most are utilizing Lexiscan. With 75% of hospitals reporting a defect in their supply chain due to shortages of aminophylline and 85% of hospitals indicating use of caffeine, the conclusion can be made the caffeine has replaced aminophylline in some clinics as the first choice in reversal of symptoms. According to anonymous answers to survey questions, a few hospitals/clinics stated they use caffeine instead of aminophylline regardless of the shortage. Due to the high number of responses to utilizing caf...
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Schobert, B., Schweikl, L., Voslar, A. Tags: Technologist Student Papers III Source Type: research
Upper reference limits of transient ischemic dilation ratio for different protocols on new-generation cadmium zinc telluride cameras: A report from REFINE SPECT registry
ConclusionsWe used a multicenter registry to establish camera-, radiotracer-, and protocol-specific upper reference limits of TID for supine position on CZT camera systems. Reference limits did not differ between D-SPECT and Discovery camera. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - May 12, 2019 Category: Nuclear Medicine Source Type: research
Hemodynamic impact of coronary stenosis using computed tomography: comparison between noninvasive fractional flow reserve and 3D fusion of coronary angiography with stress myocardial perfusion
AbstractVasodilator-stress CT perfusion imaging in addition to CT coronary angiography (CTCA) may provide a single-test alternative to nuclear stress testing, commonly used to assess hemodynamic significance of stenosis. Another alternative is fractional flow reserve (FFR) calculated from cardiac CT images. We studied the concordance between these two approaches and their relationship to outcomes. We prospectively studied 150 patients with chest pain, who underwent CTCA and regadenoson CT. CTCA images were interpreted for presence and severity of stenosis. Fused 3D displays of subendocardial X-ray attenuation with coronary...
Source: The International Journal of Cardiovascular Imaging - May 8, 2019 Category: Radiology Source Type: research
Regadenoson SPECT MPI post-troponin elevation in two different patient populations: A reliable risk-stratification tool
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - April 29, 2019 Category: Nuclear Medicine Source Type: research
Marked ST-segment elevations during regadenoson pharmacologic nuclear stress testing
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - March 17, 2019 Category: Nuclear Medicine Source Type: research
Initial experience with regadenoson stress positron emission tomography in patients with left bundle branch block: Low prevalence of septal defects and high accuracy for obstructive coronary artery disease
ConclusionsIn patients with LBBB undergoing regadenoson PET stress imaging, artifactual septal perfusion defects are rare. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - March 13, 2019 Category: Nuclear Medicine Source Type: research
Improved Visualization of the Coronary Arteries Using Motion Correction During Vasodilator Stress CT Myocardial Perfusion Imaging
ConclusionsMCR improves the visualization of coronary anatomy on sCTP images without degrading image characteristics. This algorithm is an important step towards the combined assessment of coronary anatomy and myocardial perfusion in a single scan, which will reduce study time, radiation exposure and contrast dose. (Source: European Journal of Radiology)
Source: European Journal of Radiology - March 5, 2019 Category: Radiology Source Type: research
Risk stratification with vasodilator stress SPECT myocardial perfusion imaging in patients with elevated cardiac biomarkers
ConclusionVasodilator stress (including regadenoson) MPI effectively risk stratifies patients with recently elevated cardiac biomarkers, with the increasing risk of mortality with the increasing severity of perfusion defects. It provides incremental prognostic value, in addition to clinical factors and degree of troponin elevation. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 27, 2019 Category: Nuclear Medicine Source Type: research
Regadenoson-induced asystole and ischemic EKG changes in the setting of underlying coronary disease
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 27, 2019 Category: Nuclear Medicine Source Type: research
No need for frame-wise attenuation correction in dynamic Rubidium-82 PET for myocardial blood flow quantification
ConclusionThere is no need for frame-wise AC in dynamic Rb-82 PET for MBF quantification. Single alignment seems sufficient in patients with myocardial creep. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 21, 2019 Category: Nuclear Medicine Source Type: research
Impact of regadenoson-induced myocardial creep on dynamic Rubidium-82 PET myocardial blood flow quantification
ConclusionsMyocardial creep is a frequent phenomenon when performing regadenoson-induced stress Rb-82 PET and has a significant impact on MBF values, especially in the RCA territory. As this may hamper diagnostic accuracy, myocardial creep correction seems necessary for reliable quantification. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 20, 2019 Category: Nuclear Medicine Source Type: research
Stress T1-mapping cardiovascular magnetic resonance imaging and inducible myocardial ischemia
ConclusionsMyocardium with inducible ischemia is characterized by the absence of significant T1 reactivity, but a clinically applicable approach for truly non-contrast stress T1 mapping remains to be determined. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 30, 2019 Category: Cardiology Source Type: research
The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT
AbstractThe purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5 MBq (0.014 mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3 h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstab...
Source: The International Journal of Cardiovascular Imaging - January 24, 2019 Category: Radiology Source Type: research
Safety and prognostic value of regadenoson stress cardiovascular magnetic resonance imaging in heart transplant recipients
There is a critical need for non-invasive methods to detect coronary allograft vasculopathy and to risk stratify heart transplant recipients. Vasodilator stress testing using cardiovascular magnetic resonance ... (Source: Journal of Cardiovascular Magnetic Resonance)
Source: Journal of Cardiovascular Magnetic Resonance - January 24, 2019 Category: Radiology Authors: Felipe Kazmirczak, Prabhjot S. Nijjar, Lei Zhang, Andrew Hughes, Ko-Hsuan Amy Chen, Osama Okasha, Cindy M. Martin, Mehmet Ak çakaya, Afshin Farzaneh-Far and Chetan Shenoy Tags: Research Source Type: research
Regadenoson long-lasting use induced tachyarrythmia
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - December 18, 2018 Category: Nuclear Medicine Source Type: research
