Systematic underestimation of myocardial perfusion reserve by regadenoson stress perfusion CMR —when haste makes waste
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - March 11, 2024 Category: Cardiology Source Type: research

Role of the clinical radiopharmacist in patient safety during myocardial perfusion imaging with vasodilator stress agents
CONCLUSIONS: Working in a systematic way, the radiopharmacist was able to detect a high number of issues related to regadenoson, with one out of four patients presenting some clinical contraindication. The recommendations given by the radiopharmacist were well accepted by the nuclear physicians who changed their approach contributing to increase the safety of patients referred for MPI.PMID:38184070 | DOI:10.1016/j.remnie.2023.12.005 (Source: Molecular Medicine)
Source: Molecular Medicine - January 6, 2024 Category: Molecular Biology Authors: C Salgado-Garcia A Moreno-Ballesteros P Guardia-Jimena E Sanchez-de-Mora A C Rebollo-Aguirre A Ramirez-Navarro A Santos-Bueno A Jimenez-Heffernan Source Type: research

Role of the clinical radiopharmacist in patient safety during myocardial perfusion imaging with vasodilator stress agents
CONCLUSIONS: Working in a systematic way, the radiopharmacist was able to detect a high number of issues related to regadenoson, with one out of four patients presenting some clinical contraindication. The recommendations given by the radiopharmacist were well accepted by the nuclear physicians who changed their approach contributing to increase the safety of patients referred for MPI.PMID:38184070 | DOI:10.1016/j.remnie.2023.12.005 (Source: Molecular Medicine)
Source: Molecular Medicine - January 6, 2024 Category: Molecular Biology Authors: C Salgado-Garcia A Moreno-Ballesteros P Guardia-Jimena E Sanchez-de-Mora A C Rebollo-Aguirre A Ramirez-Navarro A Santos-Bueno A Jimenez-Heffernan Source Type: research

What is this image? 2023 image 2 results: In vivo demonstration of regadenoson-induced severe ischemia on PET myocardial perfusion imaging in a patient with hypertrophic obstructive cardiomyopathy and nonobstructive coronary artery disease
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - August 21, 2023 Category: Nuclear Medicine Source Type: research

Drugs targeting adenosine signaling pathways: A current view
In conclusion, targeting purinergic signaling represents a great therapeutic challenge. The actual knowledge of the involvement of adenosinergic signaling as part of the mechanism of action of old drugs has open a path not only for drug-repurposing but also for new therapeutic strategies.PMID:37506580 | DOI:10.1016/j.biopha.2023.115184 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 28, 2023 Category: Drugs & Pharmacology Authors: Barbara Kutryb-Zaj ąc Ada Kawecka Khrystyna Nasadiuk Alicja Braczko Klaudia Stawarska Elisabetta Caiazzo Patrycja Kosza łka Carla Cicala Source Type: research

Drugs targeting adenosine signaling pathways: A current view
In conclusion, targeting purinergic signaling represents a great therapeutic challenge. The actual knowledge of the involvement of adenosinergic signaling as part of the mechanism of action of old drugs has open a path not only for drug-repurposing but also for new therapeutic strategies.PMID:37506580 | DOI:10.1016/j.biopha.2023.115184 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 28, 2023 Category: Drugs & Pharmacology Authors: Barbara Kutryb-Zaj ąc Ada Kawecka Khrystyna Nasadiuk Alicja Braczko Klaudia Stawarska Elisabetta Caiazzo Patrycja Kosza łka Carla Cicala Source Type: research

PET myocardial perfusion imaging of regadenoson-induced coronary vasospasm
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 19, 2023 Category: Nuclear Medicine Source Type: research

Accurate and efficient rapid acquisition early post-injection stress-first CZT SPECT myocardial perfusion imaging with tetrofosmin and attenuation correction
ConclusionEarly post-injection stress-only imaging using CZT SPECT/CT appears promising with Tc-99m tetrofosmin with similar image quality, reader confidence, diagnosis, and need for a rest scan. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - July 18, 2023 Category: Nuclear Medicine Source Type: research

Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling
CONCLUSIONS: The protective effect of caffeine against palmitate lipotoxicity was shown to be dependent on A1AR receptor and PKA activation. Antagonism of A1AR also protects against lipotoxicity. Targeting A1AR receptor may be a potential therapeutic intervention with which to treat MAFLD.PMID:37423170 | DOI:10.1016/j.biopha.2023.114884 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 9, 2023 Category: Drugs & Pharmacology Authors: Johanna C Arroyave-Ospina Manon Buist-Homan Martina Schmidt Han Moshage Source Type: research

Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling
CONCLUSIONS: The protective effect of caffeine against palmitate lipotoxicity was shown to be dependent on A1AR receptor and PKA activation. Antagonism of A1AR also protects against lipotoxicity. Targeting A1AR receptor may be a potential therapeutic intervention with which to treat MAFLD.PMID:37423170 | DOI:10.1016/j.biopha.2023.114884 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 9, 2023 Category: Drugs & Pharmacology Authors: Johanna C Arroyave-Ospina Manon Buist-Homan Martina Schmidt Han Moshage Source Type: research

Retraction Note: Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI
(Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - June 29, 2023 Category: Nuclear Medicine Source Type: research