Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase non-persistent genotype
CONCLUSIONS: Increased levels of Bifidobacterium indicate an adaptation of the gut microbiota upon repetitive consumption of incremental doses of lactose, which was well-tolerated as demonstrated by reduced expired hydrogen levels during the second 25g lactose HBT. Bifidobacteria metabolize lactose without gas production thereby potentially reducing intestinal gas formation in the gut of individuals with the LNP-genotype. This increased lactose tolerance possibly lifts the necessity to remove nutrient-rich dairy foods completely from the diet.REGISTRATION NUMBER OF CLINICAL TRIAL: The trial is registered at the Internation...
Source: The American Journal of Clinical Nutrition - December 30, 2023 Category: Nutrition Authors: Lonneke JanssenDuijghuijsen Ellen Looijesteijn Maartje van den Belt Beatrix Gerhard Martin Ziegler Renata Ariens Reina Tjoelker Jan Geurts Source Type: research
Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase non-persistent genotype
CONCLUSIONS: Increased levels of Bifidobacterium indicate an adaptation of the gut microbiota upon repetitive consumption of incremental doses of lactose, which was well-tolerated as demonstrated by reduced expired hydrogen levels during the second 25g lactose HBT. Bifidobacteria metabolize lactose without gas production thereby potentially reducing intestinal gas formation in the gut of individuals with the LNP-genotype. This increased lactose tolerance possibly lifts the necessity to remove nutrient-rich dairy foods completely from the diet.REGISTRATION NUMBER OF CLINICAL TRIAL: The trial is registered at the Internation...
Source: Am J Clin Nutr - December 30, 2023 Category: Nutrition Authors: Lonneke JanssenDuijghuijsen Ellen Looijesteijn Maartje van den Belt Beatrix Gerhard Martin Ziegler Renata Ariens Reina Tjoelker Jan Geurts Source Type: research
Valorization of Cheese Whey Powder by Two-Step Fermentation for Gluconic Acid and Ethanol Preparation
Appl Biochem Biotechnol. 2023 Dec 30. doi: 10.1007/s12010-023-04834-x. Online ahead of print.ABSTRACTWhey from cheesemaking is an environmental contaminant with a high biochemical oxygen demand (BOD), containing an abundance of lactose. Hence, it has the potential to be utilized in the manufacturing of bio-based chemicals that have increased value. A designed sequential fermentation approach was employed in this research to convert enzymatic hydrolysate of cheese whey (primarily consists of glucose and galactose) into gluconic acid and bio-ethanol. This conversion was achieved by utilizing Gluconobacter oxydans and Sacchar...
Source: Applied Biochemistry and Biotechnology - December 29, 2023 Category: Biochemistry Authors: Rui Zhang Fan Li Xinlu Liu Xin Zhou Kankan Jiang Source Type: research
Lactose hydrolysis in packed-and fluidized-bed reactors using a recombinant β-galactosidase immobilized on magnetic core-shell capsules
The objective of this study was to develop a bioprocess for lactose hydrolysis in diverse dairy matrices, specifically skim milk and cheese whey, utilizing column reactors employing a core-shell enzymatic system featuring β-galactosidase fused to a Cellulose Binding Domain (CBD) tag (β-galactosidase-CBD). The effectiveness of reactor configurations, including ball columns and toothed columns operating in packed and fluidized-bed modes, was evaluated for catalyzing lactose hydrolysis in both skim milk and cheese whey. In a closed system, these reactors achieved lactose hydrolysis rates of approximately 50% within 5 h unde...
Source: Bioprocess and Biosystems Engineering - December 29, 2023 Category: Biomedical Engineering Authors: Adriano Gennari Renate Simon Gaby Renard Jocelei Maria Chies Giandra Volpato Claucia Fernanda Volken de Souza Source Type: research
Lactose hydrolysis in packed-and fluidized-bed reactors using a recombinant β-galactosidase immobilized on magnetic core-shell capsules
The objective of this study was to develop a bioprocess for lactose hydrolysis in diverse dairy matrices, specifically skim milk and cheese whey, utilizing column reactors employing a core-shell enzymatic system featuring β-galactosidase fused to a Cellulose Binding Domain (CBD) tag (β-galactosidase-CBD). The effectiveness of reactor configurations, including ball columns and toothed columns operating in packed and fluidized-bed modes, was evaluated for catalyzing lactose hydrolysis in both skim milk and cheese whey. In a closed system, these reactors achieved lactose hydrolysis rates of approximately 50% within 5 h unde...
Source: Bioprocess and Biosystems Engineering - December 29, 2023 Category: Biomedical Engineering Authors: Adriano Gennari Renate Simon Gaby Renard Jocelei Maria Chies Giandra Volpato Claucia Fernanda Volken de Souza Source Type: research
A review of fermented milks: potential beneficial effects on human nutrition and health
In this study, the effects of fermented milks on human nutrition and health are mentioned. (Source: African Health Sciences)
Source: African Health Sciences - December 27, 2023 Category: African Health Authors: Yerlikaya Oktay Source Type: research
Comparative analysis of total protein, casein, lactose, and fat content in milk of cows suffering from subclinical and clinical mastitis caused by < em > Streptococcus < /em > spp
CONCLUSION: It should be emphasised that the decrease in the levels of TP, LAC and FAT was significant not only in milk from CM cows but also in milk from SCM cows. This is very unfavourable, because the reduction in the main milk components results in poor quality dairy products and impairs line processes.PMID:38143829 | PMC:PMC10740323 | DOI:10.2478/jvetres-2023-0028 (Source: Cell Research)
Source: Cell Research - December 25, 2023 Category: Cytology Authors: Mariola Bochniarz Przemys ław Błaszczyk Marek Szczubia ł Iosif Vasiu Łukasz Adaszek Katarzyna Michalak Dorota Pietras-O żga Marco Wochnik Roman D ąbrowski Source Type: research
Single and longitudinal genome-wide association studies for dairy traits available in goats with three recorded lactations
Anim Genet. 2023 Dec 22. doi: 10.1111/age.13391. Online ahead of print.ABSTRACTMilk yield and composition phenotypes are systematically recorded across several lactations in goats, but the majority of genome-wide association studies (GWAS) performed so far have rather ignored the longitudinal nature of such data. Here, we have used two different GWAS approaches to analyse data from three lactations recorded in Murciano-Granadina goats. In Analysis 1, independent GWAS have been carried out for each trait and lactation, while a single longitudinal GWAS, jointly considering all data, has been performed in Analysis 2. In both ...
Source: Animal Genetics - December 22, 2023 Category: Genetics & Stem Cells Authors: Maria Gracia Luigi-Sierra Amparo Mart ínez Martina Macri Juan Vicente Delgado Anna Castell ó Javier Fern ández Alvarez Xavier Such Jordi Jordana Marcel Amills Source Type: research
Single and longitudinal genome-wide association studies for dairy traits available in goats with three recorded lactations
Anim Genet. 2023 Dec 22. doi: 10.1111/age.13391. Online ahead of print.ABSTRACTMilk yield and composition phenotypes are systematically recorded across several lactations in goats, but the majority of genome-wide association studies (GWAS) performed so far have rather ignored the longitudinal nature of such data. Here, we have used two different GWAS approaches to analyse data from three lactations recorded in Murciano-Granadina goats. In Analysis 1, independent GWAS have been carried out for each trait and lactation, while a single longitudinal GWAS, jointly considering all data, has been performed in Analysis 2. In both ...
Source: Animal Genetics - December 22, 2023 Category: Genetics & Stem Cells Authors: Maria Gracia Luigi-Sierra Amparo Mart ínez Martina Macri Juan Vicente Delgado Anna Castell ó Javier Fern ández Alvarez Xavier Such Jordi Jordana Marcel Amills Source Type: research
Single and longitudinal genome-wide association studies for dairy traits available in goats with three recorded lactations
Anim Genet. 2023 Dec 22. doi: 10.1111/age.13391. Online ahead of print.ABSTRACTMilk yield and composition phenotypes are systematically recorded across several lactations in goats, but the majority of genome-wide association studies (GWAS) performed so far have rather ignored the longitudinal nature of such data. Here, we have used two different GWAS approaches to analyse data from three lactations recorded in Murciano-Granadina goats. In Analysis 1, independent GWAS have been carried out for each trait and lactation, while a single longitudinal GWAS, jointly considering all data, has been performed in Analysis 2. In both ...
Source: Animal Genetics - December 22, 2023 Category: Genetics & Stem Cells Authors: Maria Gracia Luigi-Sierra Amparo Mart ínez Martina Macri Juan Vicente Delgado Anna Castell ó Javier Fern ández Alvarez Xavier Such Jordi Jordana Marcel Amills Source Type: research
Retracted: Preparation of Curcumin Solid Lipid Nanoparticles Loaded with Flower-Shaped Lactose for Lung Inhalation and Preliminary Evaluation of Cytotoxicity In Vitro
Evid Based Complement Alternat Med. 2023 Dec 13;2023:9809240. doi: 10.1155/2023/9809240. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/4828169.].PMID:38125160 | PMC:PMC10732876 | DOI:10.1155/2023/9809240 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 21, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
The effect of mixing on the dispersibility of adhesive mixtures for inhalation. Comparison of high shear and Turbula mixers
This study investigates the effect of different mixers and the applicability of the mixing energy (ME) concept to dry powder formulations for inhalation. With the aim to step-wise build and expand this concept, adhesive mixtures of 2% budesonide and lactose carrier were investigated, both with 1% magnesium stearate (MgSt) added in a 'coating' step, and without, the latter referred to as 'naked' formulations. For high shear mixed formulations, the fine particle fraction (FPF) was found to increase with increasing ME up to 60% and thereafter decreased, using the Novolizer device. The data could be well fitted to the modeling...
Source: European Journal of Pharmaceutical Sciences - December 21, 2023 Category: Drugs & Pharmacology Authors: Kyrre Thalberg Love Ivarsson M årten Svensson Peter Elfman Ann Ohlsson Jackie Stuckel Ann-Marie Lyberg Source Type: research
Retracted: Preparation of Curcumin Solid Lipid Nanoparticles Loaded with Flower-Shaped Lactose for Lung Inhalation and Preliminary Evaluation of Cytotoxicity In Vitro
Evid Based Complement Alternat Med. 2023 Dec 13;2023:9809240. doi: 10.1155/2023/9809240. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/4828169.].PMID:38125160 | PMC:PMC10732876 | DOI:10.1155/2023/9809240 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 21, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
The effect of mixing on the dispersibility of adhesive mixtures for inhalation. Comparison of high shear and Turbula mixers
This study investigates the effect of different mixers and the applicability of the mixing energy (ME) concept to dry powder formulations for inhalation. With the aim to step-wise build and expand this concept, adhesive mixtures of 2 % budesonide and lactose carrier were investigated, both with 1 % magnesium stearate (MgSt) added in a 'coating' step, and without, the latter referred to as 'naked' formulations. For high shear mixed formulations, the fine particle fraction (FPF) was found to increase with increasing ME up to 60 % and thereafter decreased, using the Novolizer device. The data could be well fitted to the model...
Source: European Journal of Pharmaceutical Sciences - December 21, 2023 Category: Drugs & Pharmacology Authors: Kyrre Thalberg Love Ivarsson M årten Svensson Peter Elfman Ann Ohlsson Jackie Stuckel Ann-Marie Lyberg Source Type: research
Retracted: Preparation of Curcumin Solid Lipid Nanoparticles Loaded with Flower-Shaped Lactose for Lung Inhalation and Preliminary Evaluation of Cytotoxicity In Vitro
Evid Based Complement Alternat Med. 2023 Dec 13;2023:9809240. doi: 10.1155/2023/9809240. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2021/4828169.].PMID:38125160 | PMC:PMC10732876 | DOI:10.1155/2023/9809240 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 21, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research
