Correlating sugar transporter expression and activities to identify transporters for an orphan sugar substrate
Appl Microbiol Biotechnol. 2024 Dec;108(1):1-18. doi: 10.1007/s00253-023-12907-4. Epub 2024 Jan 8.ABSTRACTFilamentous fungi like Neurospora crassa are able to take up and metabolize important sugars present, for example, in agricultural and human food wastes. However, only a fraction of all putative sugar transporters in filamentous fungi has been characterized to date, and for many sugar substrates, the corresponding transporters are unknown. In N. crassa, only 14 out of the 42 putative major facilitator superfamily (MFS)-type sugar transporters have been characterized so far. To uncover this hidden potential for biotechn...
Source: Applied Microbiology and Biotechnology - January 8, 2024 Category: Microbiology Authors: Elisabeth Tamayo Basant Nada Isabell Hafermann J Philipp Benz Source Type: research

Exploring the potential of neem and tamarind gum as release retardants: Design and statistical optimisation of vildagliptin extended release matrix systems using D-optimal quadratic mixture design
Int J Biol Macromol. 2024 Jan 3:129136. doi: 10.1016/j.ijbiomac.2023.129136. Online ahead of print.ABSTRACTExploring the significant role of natural polymers in developing drug delivery systems has been a promising area of research interest. The current investigation uses a D-optimal quadratic mixture design to design and evaluate neem and tamarind gum-based vildagliptin extended-release matrix tablets. Studying the combination effect of gums is one of the major objectives. Initial screening studies were performed to select the factors and their levels. The variables selected at different levels in mg/tablet are neem gum, ...
Source: International Journal of Biological Macromolecules - January 5, 2024 Category: Biochemistry Authors: N Ravi Kumar G S N Koteswara Rao J Vijaya Ratna K V Ramana Murthy Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: The American Journal of Tropical Medicine and Hygiene - January 3, 2024 Category: Tropical Medicine Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: Am J Trop Med Hyg - January 3, 2024 Category: Infectious Diseases Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: The American Journal of Tropical Medicine and Hygiene - January 3, 2024 Category: Tropical Medicine Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: Am J Trop Med Hyg - January 3, 2024 Category: Infectious Diseases Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: The American Journal of Tropical Medicine and Hygiene - January 3, 2024 Category: Tropical Medicine Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: Am J Trop Med Hyg - January 3, 2024 Category: Infectious Diseases Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: Am J Trop Med Hyg - January 3, 2024 Category: Infectious Diseases Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Assessment of Antibiotic Resistance among Clinical Isolates of Enterobacteriaceae in Nepal
Am J Trop Med Hyg. 2024 Jan 2:tpmd230199. doi: 10.4269/ajtmh.23-0199. Online ahead of print.ABSTRACTClinicians face a global challenge treating infections caused by Enterobacteriaceae because of the high rate of antibiotic resistance. This cross-sectional study from the Nepal Armed Police Force Hospital, Kathmandu, Nepal, characterized resistance patterns in Enterobacteriaceae across different antimicrobial classes and assessed incidences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections. Enterobacteriaceae from clinical samples were isolated on blood and MacConkey agar, except for urine samples ...
Source: The American Journal of Tropical Medicine and Hygiene - January 3, 2024 Category: Tropical Medicine Authors: Ajaya Basnet Mahendra Raj Shrestha Basanta Tamang Nayanum Pokhrel Rajendra Maharjan Junu Richhinbung Rai Shrijana Bista Shila Shrestha Shiba Kumar Rai Source Type: research

Fisetin Treats Kidney Oxidative Stress, Inflammation, and Apoptosis in Rat Diarrhea
CONCLUSIONS: Fisetin treated diarrhea in rats by restoring kidney function, antioxidant activity, inflammatory markers, apoptosis, proteome content, and histology.PMID:38163954 | DOI:10.31083/j.fbs1504014 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Khaled M M Koriem Yousra K O Farouk Source Type: research