Stress response and adaptation mechanisms in Kluyveromyces marxianus
Adv Appl Microbiol. 2024;126:27-62. doi: 10.1016/bs.aambs.2024.02.003. Epub 2024 Mar 12.ABSTRACTKluyveromyces marxianus is a non-Saccharomyces yeast that has gained importance due to its great potential to be used in the food and biotechnology industries. In general, K. marxianus is a known yeast for its ability to assimilate hexoses and pentoses; even this yeast can grow in disaccharides such as sucrose and lactose and polysaccharides such as agave fructans. Otherwise, K. marxianus is an excellent microorganism to produce metabolites of biotechnological interest, such as enzymes, ethanol, aroma compounds, organic acids, a...
Source: Advances in Applied Microbiology - April 18, 2024 Category: Microbiology Authors: G Flores-Cos ío J A Garc ía-Béjar D Sandoval-Nu ñez L Amaya-Delgado Source Type: research

Survival of O157 and non-O157 shiga toxin-producing Escherichia coli in Korean style kimchi
Food Microbiol. 2024 Aug;121:104526. doi: 10.1016/j.fm.2024.104526. Epub 2024 Mar 30.ABSTRACTKorean style kimchi contaminated with Shiga toxin-producing Escherichia coli (STEC) O157:H7 was the cause of an outbreak in Canada from December 2021 to January 2022. To determine if this STEC O157:H7 has greater potential for survival in kimchi than other STEC, the outbreak strain and six other STEC strains (O26:H11, O91:H21, O103:H2, O121:H19, and two O157:H7) were inoculated individually at 6 to 6.5 log CFU/g into commercially sourced kimchi and incubation at 4 °C. At intervals of seven days inoculated and control kimchi was pl...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Alexander Gill Tanis McMahon Christina Ferrato Linda Chui Source Type: research

Regulation of lactose, glucose and sucrose metabolisms in S. thermophilus
Food Microbiol. 2024 Aug;121:104487. doi: 10.1016/j.fm.2024.104487. Epub 2024 Feb 12.ABSTRACTStreptococcus thermophilus is a bacterium widely used in the production of yogurts and cheeses, where it efficiently ferments lactose, the saccharide naturally present in milk. It is also employed as a starter in dairy- or plant-based fermented foods that contain saccharides other than lactose (e.g., sucrose, glucose). However, little is known about how saccharide use is regulated, in particular when saccharides are mixed. Here, we determine the effect of the 5 sugars that S. thermophilus is able to use, at different concentration ...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: C Gasser J M Faurie F Rul Source Type: research

Serratia montpellierensis sp. nov., Isolated from Laboratory-Reared Parasitic Wasps Psyttalia lounsburyii Silvestri and Psyttalia ponerophaga Silvestri (Hymenoptera: Braconidae)
Curr Microbiol. 2024 Apr 18;81(6):146. doi: 10.1007/s00284-024-03666-0.ABSTRACTTwo strains of bacteria, PsyLou2AT and PsyPon4B, were isolated from adult braconid wasps Psyttalia lounsburyii and Psyttalia ponerophaga, respectively. These laboratory-reared wasps were investigated as agents for biological control of the olive fruit fly, Bactrocera oleae. Analysis of 16S rRNA genes of the two isolates demonstrated that they were highly related and belonged to the genus Serratia. Genomic sequencing of these isolates revealed genomes of 5,152,551 bp and 5,154,385 bp for PsyLou2AT and PsyPon4B, respectively, and both genomes had ...
Source: Current Microbiology - April 18, 2024 Category: Microbiology Authors: Michael B Blackburn M élanie Tannières Michael E Sparks Dawn E Gundersen-Rindal Marie-Claude Bon Source Type: research

Controllable detection threshold achieved through the toehold switch system in a mercury ion whole-cell biosensor
This study confirms the feasibility and performance of biosensor with controllable detection threshold, providing a new detection method and new ideas for expanding the detection range of biosensors while ensuring rapid and convenient measurements without compromising sensitivity.PMID:38608495 | DOI:10.1016/j.bios.2024.116283 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - April 12, 2024 Category: Biotechnology Authors: Qinglong Zhang Zixiang Wei Xiaoqiang Jia Source Type: research

Controllable detection threshold achieved through the toehold switch system in a mercury ion whole-cell biosensor
This study confirms the feasibility and performance of biosensor with controllable detection threshold, providing a new detection method and new ideas for expanding the detection range of biosensors while ensuring rapid and convenient measurements without compromising sensitivity.PMID:38608495 | DOI:10.1016/j.bios.2024.116283 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - April 12, 2024 Category: Biotechnology Authors: Qinglong Zhang Zixiang Wei Xiaoqiang Jia Source Type: research

Effects of supplementing cassava root silage to grazing dairy cows on nutrient utilization, milk production and composition in the tropics
In conclusion, CRS may be a potential corn meal replacer in the supplement of dairy cows under tropical conditions. (Source: Tropical Animal Health and Production)
Source: Tropical Animal Health and Production - April 12, 2024 Category: Veterinary Research Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Development of Losartan Orally Disintegrating Tablets by Direct Compression: a Cost-Effective Approach to Improve Paediatric Patient's Compliance
In conclusion, the ODTs were successfully developed and characterised, suggesting a potential means to accomplish a final prototype that enables an improvement in childhood arterial hypertension treatment.PMID:38589718 | DOI:10.1208/s12249-024-02796-9 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Candela Juan Loreana Gallo Noelia Gonzalez Vidal Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Development of Losartan Orally Disintegrating Tablets by Direct Compression: a Cost-Effective Approach to Improve Paediatric Patient's Compliance
In conclusion, the ODTs were successfully developed and characterised, suggesting a potential means to accomplish a final prototype that enables an improvement in childhood arterial hypertension treatment.PMID:38589718 | DOI:10.1208/s12249-024-02796-9 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Candela Juan Loreana Gallo Noelia Gonzalez Vidal Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research