Effects of supplementing cassava root silage to grazing dairy cows on nutrient utilization, milk production and composition in the tropics
In conclusion, CRS may be a potential corn meal replacer in the supplement of dairy cows under tropical conditions. (Source: Tropical Animal Health and Production)
Source: Tropical Animal Health and Production - April 12, 2024 Category: Veterinary Research Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Development of Losartan Orally Disintegrating Tablets by Direct Compression: a Cost-Effective Approach to Improve Paediatric Patient's Compliance
In conclusion, the ODTs were successfully developed and characterised, suggesting a potential means to accomplish a final prototype that enables an improvement in childhood arterial hypertension treatment.PMID:38589718 | DOI:10.1208/s12249-024-02796-9 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Candela Juan Loreana Gallo Noelia Gonzalez Vidal Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Development of Losartan Orally Disintegrating Tablets by Direct Compression: a Cost-Effective Approach to Improve Paediatric Patient's Compliance
In conclusion, the ODTs were successfully developed and characterised, suggesting a potential means to accomplish a final prototype that enables an improvement in childhood arterial hypertension treatment.PMID:38589718 | DOI:10.1208/s12249-024-02796-9 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Candela Juan Loreana Gallo Noelia Gonzalez Vidal Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

A Highly Sensitive Structure Based on Prism, Silver, and Titanium Dioxide for Biochemical Sensing Applications
AbstractIn this paper, a refractive index (RI) sensor with prism configuration is proposed and numerically investigated for sensing applications. The sensor design is based on a BK7 prism, silver (Ag), and titanium dioxide (TiO2). Important enhancement in the sensitivity and reflection deep is obtained by optimizing some geometric and optical parameters. The transfer matrix method (TMM) is employed to investigate the reflectance of the sensor at wavelength interrogation. RI sensitivity (SRI), figure of merit (FoM), and quality factor (QF) are three important parameters that are considered to determine the design performanc...
Source: Plasmonics - April 3, 2024 Category: Biomedical Science Source Type: research

Optimizing semen cryopreservation in Calomys laucha: a step forward in rodent reproductive research
CONCLUSION: Our findings suggest that a cryopreservation medium containing 0.3 M glucose can contribute to the safeguarding C. laucha rodent semen. https://doi.org/10.54680/fr24210110612.PMID:38557992 (Source: Cryo-Letters)
Source: Cryo-Letters - April 1, 2024 Category: Biology Authors: C D Corcini J Vilela N Gatti B Mion N Castro R T Franca A S Varela Junior Source Type: research