Effect of Powdered Cellulose Nanofiber with Different Particle Sizes on the Physical Properties of Tablets Manufactured via Direct Compression
Chem Pharm Bull (Tokyo). 2023;71(12):887-896. doi: 10.1248/cpb.c23-00587.ABSTRACTDirect compression is a tableting technique that involves a few steps in non-demanding manufacturing conditions. High strength and rapid disintegration of tablet formulations were previously achieved through the addition of cellulose nanofibers (CNFs), which have recently attracted attention as a high-performance biomass material. However, CNF addition results in greater variation in tablet weight and drug content, potentially due to differences in particle size between CNF and other additives. Herein, we used pulverized CNF to evaluate the ef...
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Shohei Nakamura Mai Jinno Momoka Hamaoka Ayumi Sakurada Takatoshi Sakamoto Source Type: research
Effect of Powdered Cellulose Nanofiber with Different Particle Sizes on the Physical Properties of Tablets Manufactured via Direct Compression
Chem Pharm Bull (Tokyo). 2023;71(12):887-896. doi: 10.1248/cpb.c23-00587.ABSTRACTDirect compression is a tableting technique that involves a few steps in non-demanding manufacturing conditions. High strength and rapid disintegration of tablet formulations were previously achieved through the addition of cellulose nanofibers (CNFs), which have recently attracted attention as a high-performance biomass material. However, CNF addition results in greater variation in tablet weight and drug content, potentially due to differences in particle size between CNF and other additives. Herein, we used pulverized CNF to evaluate the ef...
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Shohei Nakamura Mai Jinno Momoka Hamaoka Ayumi Sakurada Takatoshi Sakamoto Source Type: research
Effect of Powdered Cellulose Nanofiber with Different Particle Sizes on the Physical Properties of Tablets Manufactured via Direct Compression
Chem Pharm Bull (Tokyo). 2023;71(12):887-896. doi: 10.1248/cpb.c23-00587.ABSTRACTDirect compression is a tableting technique that involves a few steps in non-demanding manufacturing conditions. High strength and rapid disintegration of tablet formulations were previously achieved through the addition of cellulose nanofibers (CNFs), which have recently attracted attention as a high-performance biomass material. However, CNF addition results in greater variation in tablet weight and drug content, potentially due to differences in particle size between CNF and other additives. Herein, we used pulverized CNF to evaluate the ef...
Source: Chemical and Pharmaceutical Bulletin - December 3, 2023 Category: Drugs & Pharmacology Authors: Shohei Nakamura Mai Jinno Momoka Hamaoka Ayumi Sakurada Takatoshi Sakamoto Source Type: research
Simultaneous medium chain carboxylic acids and 1,3-propanediol production in a bioaugmented lactate-based chain elongation induced with glycerol
The objective was to investigate the impact of the bioaugmentation on chain elongation process using glycerol, lactate and lactose as substrates in an open culture fermentation. In the batch trials the highest selectivity for chain elongation product, i.e. caproate, was observed in trials inoculated with co-culture of Megasphaera elsdenii and Eubacterium limosum grown on glycerol (28.6 %), and in non-bioaugmented open culture run on lactose + lactate (14.8 %). The results showed that E. limosum, out of two bioaugmented strains, was able to survive in the open culture. A continuous open culture fermentation of glycerol led ...
Source: Bioresource Technology - December 2, 2023 Category: Biotechnology Authors: Anna Duber Roman Zagrodnik Wojciech Juzwa Natalia Gutowska Piotr Oleskowicz-Popiel Source Type: research
Terahertz reconfigurable metasensor for specific recognition multiple and mixed chemical substances based on AIT fingerprint enhancement
Talanta. 2023 Nov 25;269:125481. doi: 10.1016/j.talanta.2023.125481. Online ahead of print.ABSTRACTTerahertz (THz) fingerprint metasensing is an effective method to identify chemical substances in a rapid and non-destructive way. Currently, two main principles are used in THz metasensing: the change of the real part of permittivity causing the dip resonance frequency deviation, and the fingerprint peak of the imaginary part of permittivity causing the dip resonance splitting (absorption induced transparency, AIT). Most previous work investigated AIT detection for only single chemical substance. The suitable AIT metasensor ...
Source: Talanta - December 1, 2023 Category: Chemistry Authors: Lihao Huang Hongyan Cao Lin Chen Yi Ma Yihan Yang Xiaoyang Liu Wenqi Wang Yiming Zhu Songlin Zhuang Source Type: research
