Dietary therapies for adult and pediatric inflammatory bowel disease
Nutr Clin Pract. 2024 Mar 20. doi: 10.1002/ncp.11146. Online ahead of print.ABSTRACTDiet is an environmental exposure implicated in the development of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Dietary therapy is also a tool for management of these conditions. Nutrition therapy for IBD has been shown to reduce intestinal inflammation, promote healing, and alleviate symptoms, as well as improve patients' nutrition status. Although the mechanisms of action of most nutrition therapies for IBD are not well understood, the diets are theorized to eliminate triggers for gut dysbi...
Source: Nutrition in Clinical Practice - March 20, 2024 Category: Nutrition Authors: Jessica Deas Neha D Shah Gauree G Konijeti Abigail Lundin Olivia Lanser Pooja Magavi Sabina Ali Source Type: research
Dietary therapies for adult and pediatric inflammatory bowel disease
Nutr Clin Pract. 2024 Mar 20. doi: 10.1002/ncp.11146. Online ahead of print.ABSTRACTDiet is an environmental exposure implicated in the development of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Dietary therapy is also a tool for management of these conditions. Nutrition therapy for IBD has been shown to reduce intestinal inflammation, promote healing, and alleviate symptoms, as well as improve patients' nutrition status. Although the mechanisms of action of most nutrition therapies for IBD are not well understood, the diets are theorized to eliminate triggers for gut dysbi...
Source: Nutrition in Clinical Practice - March 20, 2024 Category: Nutrition Authors: Jessica Deas Neha D Shah Gauree G Konijeti Abigail Lundin Olivia Lanser Pooja Magavi Sabina Ali Source Type: research
Dietary therapies for adult and pediatric inflammatory bowel disease
Nutr Clin Pract. 2024 Mar 20. doi: 10.1002/ncp.11146. Online ahead of print.ABSTRACTDiet is an environmental exposure implicated in the development of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Dietary therapy is also a tool for management of these conditions. Nutrition therapy for IBD has been shown to reduce intestinal inflammation, promote healing, and alleviate symptoms, as well as improve patients' nutrition status. Although the mechanisms of action of most nutrition therapies for IBD are not well understood, the diets are theorized to eliminate triggers for gut dysbi...
Source: Nutrition in Clinical Practice - March 20, 2024 Category: Nutrition Authors: Jessica Deas Neha D Shah Gauree G Konijeti Abigail Lundin Olivia Lanser Pooja Magavi Sabina Ali Source Type: research
Dietary therapies for adult and pediatric inflammatory bowel disease
Nutr Clin Pract. 2024 Mar 20. doi: 10.1002/ncp.11146. Online ahead of print.ABSTRACTDiet is an environmental exposure implicated in the development of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Dietary therapy is also a tool for management of these conditions. Nutrition therapy for IBD has been shown to reduce intestinal inflammation, promote healing, and alleviate symptoms, as well as improve patients' nutrition status. Although the mechanisms of action of most nutrition therapies for IBD are not well understood, the diets are theorized to eliminate triggers for gut dysbi...
Source: Nutrition in Clinical Practice - March 20, 2024 Category: Nutrition Authors: Jessica Deas Neha D Shah Gauree G Konijeti Abigail Lundin Olivia Lanser Pooja Magavi Sabina Ali Source Type: research
Could lactose-free foods influence the gut microbiome?
Nat Prod Res. 2024 Mar 18:1-2. doi: 10.1080/14786419.2024.2325584. Online ahead of print.NO ABSTRACTPMID:38497246 | DOI:10.1080/14786419.2024.2325584 (Source: Natural Product Research)
Source: Natural Product Research - March 18, 2024 Category: Biochemistry Authors: Eleonora Di Salvo Nicola Cicero Source Type: research
Highly-efficient in vivo production of lacto-N-fucopentaose V by a regio-specific α1,3/4-fucosyltransferase from Bacteroides fragilis NCTC 9343
In this study, the biosynthetic pathway of LNFP V was examined in Escherichia coli. The previously constructed E. coli efficiently producing lacto-N-tetraose was used as the starting strain. GDP-fucose pathway module and a regio-specific glycosyltransferase with α1,3-fucosylation activity were introduced to realize the efficient synthesis of LNFP V. The α1,3/4-fucosyltransferase from Bacteroides fragilis was selected as the best enzyme for in vivo biosynthesis of LNFP V from nine candidates, with the highest titer and the lowest by-product accumulation. A beneficial variant K128D was obtained to further enhance LNFP V ti...
Source: International Journal of Biological Macromolecules - March 18, 2024 Category: Biochemistry Authors: Ningning Wang Yingying Zhu Liang Wang Zhaolin Huang Zeyu Li Wei Xu Wanmeng Mu Source Type: research
Could lactose-free foods influence the gut microbiome?
Nat Prod Res. 2024 Mar 18:1-2. doi: 10.1080/14786419.2024.2325584. Online ahead of print.NO ABSTRACTPMID:38497246 | DOI:10.1080/14786419.2024.2325584 (Source: Natural Product Research)
Source: Natural Product Research - March 18, 2024 Category: Biochemistry Authors: Eleonora Di Salvo Nicola Cicero Source Type: research
Highly-efficient in vivo production of lacto-N-fucopentaose V by a regio-specific α1,3/4-fucosyltransferase from Bacteroides fragilis NCTC 9343
In this study, the biosynthetic pathway of LNFP V was examined in Escherichia coli. The previously constructed E. coli efficiently producing lacto-N-tetraose was used as the starting strain. GDP-fucose pathway module and a regio-specific glycosyltransferase with α1,3-fucosylation activity were introduced to realize the efficient synthesis of LNFP V. The α1,3/4-fucosyltransferase from Bacteroides fragilis was selected as the best enzyme for in vivo biosynthesis of LNFP V from nine candidates, with the highest titer and the lowest by-product accumulation. A beneficial variant K128D was obtained to further enhance LNFP V ti...
Source: International Journal of Biological Macromolecules - March 18, 2024 Category: Biochemistry Authors: Ningning Wang Yingying Zhu Liang Wang Zhaolin Huang Zeyu Li Wei Xu Wanmeng Mu Source Type: research
“It’s Not a Gas”: The Future of Testing for Lactose Intolerance
Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Added Value of 13C Analysis in Breath Tests in H2-Negative Subjects to Diagnose Lactose Malabsorption: A Proof of Concept Study
ConclusionsIn individuals with genetically demonstrated lactase non-persistence and negative hydrogen breath test, the use of13C-lactose with measurement of13CO2 excretion and hydrogen is a well-performing test to detect the lactose malabsorption and performs better than methane in our cohort. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
“It’s Not a Gas”: The Future of Testing for Lactose Intolerance
Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
Added Value of 13C Analysis in Breath Tests in H2-Negative Subjects to Diagnose Lactose Malabsorption: A Proof of Concept Study
ConclusionsIn individuals with genetically demonstrated lactase non-persistence and negative hydrogen breath test, the use of13C-lactose with measurement of13CO2 excretion and hydrogen is a well-performing test to detect the lactose malabsorption and performs better than methane in our cohort. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 18, 2024 Category: Gastroenterology Source Type: research
The effect of oral analgesic premedication on the success rate of inferior alveolar nerve block for teeth with irreversible pulpitis: A randomized clinical trial
Conclusions: Premedication with Pharmapain (an anti-inflammatory agent) and dexamethasone (a corticosteroid) does not enhance the success rate of the IANB technique in mandibular molars with irreversible pulpitis compared to placebo. However, the use of dexamethasone was significantly more effective than Pharmapain in reducing pain severity at inserting the first endodontic file. (Source: Journal of Dental Materials and Techniques)
Source: Journal of Dental Materials and Techniques - March 17, 2024 Category: Dentistry Source Type: research
Therapeutic potential of popular fermented dairy products and its benefits on human health
Front Nutr. 2024 Feb 28;11:1328620. doi: 10.3389/fnut.2024.1328620. eCollection 2024.ABSTRACTIn the current arena of time, the transformation of society has improved the standard of living in terms of lifestyle and their nutritional demands and requirements. The microorganisms under controlled conditions and the enzymatic transformation of dietary components are the processes that resulted in fermented foods and beverages. Fermented dairy products with high nutritional value are "the pearls of the dairy industry." During fermentation, fermented dairy products produce bioactive compounds and metabolites derived from bacteri...
Source: Cancer Control - March 14, 2024 Category: Cancer & Oncology Authors: Gul Naz Saleem Ruixia Gu Hengxian Qu Gul Bahar Khaskheli Imran Rashid Rajput Muhammad Qasim Xia Chen Source Type: research
Challenges and mitigation strategies associated with Burkholderia cepacia complex contamination in pharmaceutical manufacturing
Arch Microbiol. 2024 Mar 14;206(4):159. doi: 10.1007/s00203-024-03921-9.ABSTRACTBurkholderia cepacia complex (BCC) is a Gram-negative, non-spore-forming bacterium with more than 20 opportunistic pathogenic species, most commonly found in soil and water. Due to their rapid mutation rates, these organisms are adaptable and possess high genomic plasticity. BCC can cause life-threatening infections in immunocompromised individuals, such as those with cystic fibrosis, chronic granulomatous disease, and neonates. BCC contamination is a significant concern in pharmaceutical manufacturing, frequently causing non-sterile product re...
Source: Archives of Microbiology - March 14, 2024 Category: Microbiology Authors: Sethuraman Prem Kumar Karupanagounder Thangaraj Uthra Vellapandian Chitra Narayanasamy Damodharan Gururaja Perumal Pazhani Source Type: research
