Kava for Generalized Anxiety Disorder: A Review of Current Evidence
The Journal of Alternative and Complementary Medicine, Ahead of Print. (Source: The Journal of Alternative and Complementary Medicine)
Source: The Journal of Alternative and Complementary Medicine - April 11, 2018 Category: Complementary Medicine Authors: Soo Liang Ooi Penny Henderson Sok Cheon Pak Source Type: research
Mp40-15 does mri perform differently in men undergoing targeted biopsy for evaluation of prostate cancer versus those on active surveillance?
Multi-parametric MRI (mpMRI) of the prostate has emerged as the most reliable method for localizing prostate cancer(pCa). We compared mpMRI performance for detection of pCa between men being evaluated for pCa and those considering active surveillance (AS). (Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: Marcelo P Barboza, Isildinha M. Reis, Feng Miao, Nachiketh Soodana Prakash, Maria C. Velasquez, Rosa Castillo, Chad R. Ritch, Mark L. Gonzalgo, Bruce Kava, Ramgopal Satyanarayana, Dipen J. Parekh, Sanoj Punnen Tags: Prostate Cancer: Detection & Screening III Source Type: research
Molecules, Vol. 23, Pages 616: Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
Ul-Haq
Syed Shah
Flavokawain B (1) is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB), about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB derivatives. All compounds were evaluated for their cytotoxic properties against two breast cancer cell lines, MCF-7 and MDA-MB-231, thus establishing the structure–activity relationship. The FKB derivatives 16 (IC50 = 6.50 ± 0.40 and 4.12 ± 0.20 μg/mL), 15 (IC50 = 5.50 ± 0.35 and 6.50 ± 1.40 μg/mL) and...
Source: Molecules - March 8, 2018 Category: Chemistry Authors: Addila Abu Bakar Muhammad Akhtar Norlaily Mohd Ali Swee Yeap Ching Quah Wan-Sin Loh Noorjahan Alitheen Seema Zareen Zaheer Ul-Haq Syed Shah Tags: Article Source Type: research
Complementary and Alternative Medicine Treatments for Generalized Anxiety Disorder: Systematic Review and Meta-analysis of Randomized Controlled Trials
ConclusionEvidence about efficacy/safety of most CAM methods in GAD is limited. Apparent efficacy of certain herbal preparations and body-based therapies requires further confirmation. (Source: Advances in Therapy)
Source: Advances in Therapy - March 5, 2018 Category: Drugs & Pharmacology Source Type: research
3:08 PM Abstract No. 4 Treating refractory hematuria of prostatic origin with prostate artery embolization: single-institution experience in 12 patients
Publication date: April 2018 Source:Journal of Vascular and Interventional Radiology, Volume 29, Issue 4, Supplement Author(s): S. Bhatia, S. Gomez, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - March 2, 2018 Category: Radiology Source Type: research
3:48 PM Abstract No. 9 Prostate artery embolization for prostate volumes ≥ 80g vs. & lt;80g - clinical outcomes from a single institution
Publication date: April 2018 Source:Journal of Vascular and Interventional Radiology, Volume 29, Issue 4, Supplement Author(s): S. Bhatia, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - March 2, 2018 Category: Radiology Source Type: research
3:16 PM Abstract No. 5 Clinical outcomes measures in the use of prostate artery embolization for prostates ≥80 grams: a single-center experience in 110 patients
Publication date: April 2018 Source:Journal of Vascular and Interventional Radiology, Volume 29, Issue 4, Supplement Author(s): S. Bhatia, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - March 2, 2018 Category: Radiology Source Type: research
3:08 PM Abstract No. 4 Treating refractory hematuria of prostatic origin with prostate artery embolization: single-institution experience in 12 patients
To assess the safety and feasibility of prostate artery embolization (PAE) for refractory hematuria of prostatic origin (RHPO) in patients with benign prostatic hyperplasia (BPH) and in the post-surgical setting. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - February 27, 2018 Category: Radiology Authors: S. Bhatia, S. Gomez, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh Tags: Scientific Session 1: Embolization: Prostatic Artery Source Type: research
3:48 PM Abstract No. 9 Prostate artery embolization for prostate volumes ≥ 80g vs. < 80g - clinical outcomes from a single institution
To compare the efficacy of prostate artery embolization (PAE) for the treatment of benign prostatic hyperplasia (BPH) for prostates ≥80 g and prostates (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - February 27, 2018 Category: Radiology Authors: S. Bhatia, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh Tags: Scientific Session 1: Embolization: Prostatic Artery Source Type: research
3:16 PM Abstract No. 5 Clinical outcomes measures in the use of prostate artery embolization for prostates ≥80 grams: a single-center experience in 110 patients
To evaluate the efficacy of prostate artery embolization (PAE) for the treatment of benign prostatic hyperplasia (BPH) for prostates ≥80 g. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - February 27, 2018 Category: Radiology Authors: S. Bhatia, V. Sinha, S. Harward, C. Gomez, B. Kava, D. Parekh Tags: Scientific Session 1: Embolization: Prostatic Artery Source Type: research
TFCC Injuries: Meta-Analysis and Comparison of Diagnostic Imaging Modalities
Conclusion This study represents the largest meta-analysis to date to compare multiple imaging modalities for the diagnosis of TFCC injuries. Pooled data demonstrated that CTA and MRA had statistically equivalent sensitivity and specificity for the diagnosis of TFCC injuries. Diagnostic accuracy was highest for central TFCC injuries. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text (Source: Journal of Wrist Surgery)
Source: Journal of Wrist Surgery - February 14, 2018 Category: Orthopaedics Authors: Treiser, Matthew D. Crawford, Kava Iorio, Matthew L. Tags: Survey Source Type: research
Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity.
In conclusions, yangonin produces protective effect against LCA-induced hepatotoxity and cholestasis due to FXR-mediated regulation. Yangonin may be an effective approach for the prevention against cholestatic liver diseases.
PMID: 29427579 [PubMed - as supplied by publisher] (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - February 7, 2018 Category: Drugs & Pharmacology Authors: Kong Y, Gao X, Wang C, Ning C, Liu K, Liu Z, Sun H, Ma X, Sun P, Meng Q Tags: Eur J Pharmacol Source Type: research
The Impact of Immediate Salvage Surgery on Corporeal Length Preservation in Patients Presenting with Penile Implant Infections
Removal of an infected penile implant often results in corporeal fibrosis, irreversible penile shortening and dissatisfaction with future implant surgery. Salvage surgery may avoid these problems but to our knowledge no study to date has evaluated these specific end points. We evaluated patients who presented to our center with an infected implant to determine the impact of salvage surgery on penile length. (Source: The Journal of Urology)
Source: The Journal of Urology - February 2, 2018 Category: Urology & Nephrology Authors: Diana M. Lopategui, Raymond R. Balise, Layla A. Bouzoubaa, Steven K. Wilson, Bruce R. Kava Tags: Adult Urology Source Type: research
The impact of immediate salvage surgery on corporeal length preservation in patients presenting with penile implant infections
Removal of an infected penile implant often results in corporeal fibrosis, irreversible penile shortening, and dissatisfaction with future implant surgery. Salvage surgery may avoid these problems, but to date no study has evaluated these specific endpoints. Patients presenting to our center with infected implants were evaluated to determine the impact of salvage surgery on penile length. (Source: The Journal of Urology)
Source: The Journal of Urology - February 2, 2018 Category: Urology & Nephrology Authors: Diana M. Lopategui, Raymond R. Balise, Layla A. Bouzoubaa, Steven K. Wilson, Bruce R. Kava Source Type: research
RecBCD (Exonuclease V) is inhibited by DNA adducts produced by cisplatin and ultraviolet light.
In this study, DNA sequences were damaged with cisplatin or UV followed by RecBCD treatment. DNA damaging agents such as cisplatin and UV induce the formation of intrastrand adducts in the DNA template. It was demonstrated that RecBCD degradation was inhibited by either cisplatin-damaged or UV-damaged DNA sequences. This is the first occasion that RecBCD has been demonstrated to be inhibited by DNA adducts induced by cisplatin or UV. In addition, we quantified the amounts of DNA remaining after RecBCD treatment and observed that the level of inhibition was concentration and dose dependent. A DNA-targeted 9-aminoacridinecar...
Source: Biochemical and Biophysical Research communications - December 27, 2017 Category: Biochemistry Authors: Leung WY, Chung LH, Kava HW, Murray V Tags: Biochem Biophys Res Commun Source Type: research
