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Correction to "Kava-241 reduced periodontal destruction in a collagen antibody primed Porphyromonas gingivalis model of periodontitis"
J Clin Periodontol. 2024 Apr 3. doi: 10.1111/jcpe.13977. Online ahead of print.NO ABSTRACTPMID:38569578 | DOI:10.1111/jcpe.13977 (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - April 3, 2024 Category: Dentistry Source Type: research

Addressing differences in cancer: a framework for synergistic programming in cancer prevention and control
Conclusions: This paper presents an applied framework for cancer prevention and control to address cancer differences. Because the framework highlights determinants and factors that influence cancer risk at multiple levels, it can be used to inform the development, implementation, and evaluation of interventions to address cancer morbidity and mortality.PMID:38562683 | PMC:PMC10984020 | DOI:10.21203/rs.3.rs-4046415/v1 (Source: Cancer Control)
Source: Cancer Control - April 2, 2024 Category: Cancer & Oncology Authors: Ciaran M Fairman Christine M Kava K Beima-Sofie M Sakhuja M Masud E Dias J Sheng J Gorzelitz A Morshed B B Green M B Skiba P Madhivanan N Parthasarathy R Hirschey M W Vander Weg J Hebert Source Type: research

Flavokawain C inhibits proliferation and migration of liver cancer cells through FAK/PI3K/AKT signaling pathway
CONCLUSIONS: These findings identified that flavokawain C is a promising anticancer agent for liver cancer treatment.PMID:38460052 | DOI:10.1007/s00432-024-05639-z (Source: Cell Research)
Source: Cell Research - March 9, 2024 Category: Cytology Authors: Rong Wang Rizhao Li Huibing Yang Xuejiao Chen Liangliang Wu Xiaohui Zheng Yuepeng Jin Source Type: research

Flavokawain C inhibits proliferation and migration of liver cancer cells through FAK/PI3K/AKT signaling pathway
ConclusionsThese findings identified that flavokawain C is a promising anticancer agent for liver cancer treatment. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - March 9, 2024 Category: Cancer & Oncology Source Type: research

Multienzymatic biotransformation of flavokawain B by entomopathogenic filamentous fungi: structural modifications and pharmacological predictions
Flavokawain B is one of the naturally occurring chalcones in the kava plant (Piper methysticum). It exhibits anticancer, anti-inflammatory and antimalarial properties. Due to its therapeutic potential, flavokawai... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - February 24, 2024 Category: Microbiology Authors: Pawe ł Chlipała, Tomasz Tronina, Monika Dymarska, Monika Urbaniak, Ewa Kozłowska, Łukasz Stępień, Edyta Kostrzewa-Susłow and Tomasz Janeczko Tags: Research Source Type: research

On a remote Pacific island, clues to El Ni ño’s future are preserved in ancient reefs
Related podcast A new way for the heart and brain to ‘talk’ to each other, and Earth’s future weather written in ancient coral reefs BY Sarah Crespi , Kevin McLean , Paul Voosen Vanuatu— The 500 residents of Tanovusvus do not typically worry about water. The village hugs the coast of Espiritu Santo, the largest island here in Vanuatu, a tropical archipelago in the western South Pacific Ocean. The lush foliage that surroun...
Source: Science of Aging Knowledge Environment - February 1, 2024 Category: Geriatrics Source Type: research

Neuroactivity screening of botanical extracts using microelectrode array (MEA) recordings
Food Chem Toxicol. 2024 Jan 6:114438. doi: 10.1016/j.fct.2024.114438. Online ahead of print.ABSTRACTToxicity testing of botanicals is challenging because of their chemical complexity and variability. Since botanicals may affect many different modes of action involved in neuronal function, we used microelectrode array (MEA) recordings of primary rat cortical cultures to screen 16 different botanical extracts for their effects on cell viability and neuronal network function in vitro. Our results demonstrate that extract materials (50 μg/mL) derived from goldenseal, milk thistle, tripterygium, and yohimbe decrease mitochondr...
Source: Food and Chemical Toxicology - January 8, 2024 Category: Food Science Authors: Regina G D M van Kleef Michelle R Embry Constance A Mitchell Remco H S Westerink Source Type: research

Key elements in the quality assessment of a type 3 medication review
Conclusion: There was widespread agreement on the hierarchy of the quality assessment criteria for MR3s. Minor differences were related to the experience of the participants. With these results and a small number of suggested extra criteria, a quality assessment instrument for MR3 can be created. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 4, 2023 Category: Drugs & Pharmacology Source Type: research

Cigarette Smoking Motives and Stages of Change in Smoking Cessation Among Veterans: Differences by Gender and Sexual Orientation
CONCLUSION: Smoking cessation interventions may benefit from enhancing peer support for gay men. Given bisexual and heterosexual women were in less advance stages of change, there may be a greater need for motivational interventions to encourage quitting and additional support to assist with cessation efforts. Overall, findings highlight the diversity of cigarette use within LGB communities.PMID:37643248 | DOI:10.1177/08901171231197147 (Source: American Journal of Health Promotion : AJHP)
Source: American Journal of Health Promotion : AJHP - August 29, 2023 Category: International Medicine & Public Health Authors: Raymond A Ruiz Keren Lehavot Jaimee L Heffner Christine M Kava India J Ornelas Source Type: research