Outcomes of Young Infants with Hypothermia Evaluated in the Emergency Department
To assess the prevalence of serious infections and mortality among infants ≤90 days of age presenting to the emergency department with hypothermia. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Sriram Ramgopal, Kathleen A. Noorbakhsh, Christopher M. Pruitt, Paul L. Aronson, Elizabeth R. Alpern, Robert W. Hickey Tags: Original Article Source Type: research

Corrigendum
Discussion section. The sentence should read “Although the estimated worldwide incidence (approximately 1/ 14 000 to 1/18 000) is higher than the incidence we have reported, it falls within our 95% CI.16” Additionally, Table I and Table II have been updated for clarity. The article has since been corrected. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Tags: Correction Source Type: research

Comparison of Evolution of Aortic Root Dilation and Ghent Criteria in Preadolescents and Adolescents with and without Marfan Syndrome
To determine whether the Ghent Criteria (2010) can be reliably used in evaluating preadolescents and adolescents for Marfan syndrome by comparing aortic growth, systemic scores, and anthropometric features in individuals with and without Marfan syndrome. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Danielle C. Monteil, Amy Shikany, Deema Aljeaid, Ashley Parrott, Justin T. Tretter, Jeanne James, Lisa J. Martin, K. Nicole Weaver Tags: Original Article Source Type: research

The Impact of Attachment-Disrupting Adverse Childhood Experiences on Child Behavioral Health
To describe patterns of overall, within-household, and community adverse childhood experiences (ACEs) among children in vulnerable neighborhoods and to identify which individual ACEs, over and above overall ACE level, predict need for behavioral health services. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Kristen R. Choi, Tatum Stewart, Eric Fein, Michael McCreary, Kristen N. Kenan, Jewel D. Davies, Sara Naureckas, Bonnie T. Zima Tags: Original Article Source Type: research

Early Growth Patterns and Cardiac Structure and Function at Midlife: Northern Finland 1966 Birth Cohort Study
To evaluate the influence of early growth patterns that have previously been associated with later cardiometabolic risk on cardiac left ventricular (LV) structure and function in midlife. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Nelli Korpela, Kari Kaikkonen, Juha Auvinen, Mikko P. Tulppo, Juhani Junttila, Juha Perki ömäki, Marjo-Riitta Järvelin, Heikki V. Huikuri, Antti M. Kiviniemi Tags: Original Article Source Type: research

Giving youth the real facts about the opioid crisis
Targeted education has become an important strategy in the continuing battle against the opioid crisis, and addiction in general. For youth in particular, the messenger and method are critical, but equally important is understanding from what foundation this information will be received. With that in mind Harbaugh et al, as reported in this volume of The Journal, sought to understand the beliefs and perceptions of youth aged 14-24 around pain medication and opioids. They used an approach uniquely suited for engagement, MyVoice, a national framework to conduct polling via text messaging. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Denise M. Goodman Tags: The Editors' Perspectives Source Type: research

Do you hear what I hear? ECHO and autism
Autism spectrum disorder (ASD) is now estimated to occur in 1 of every 59 children in the US. The direct and indirect costs of caring for children and adults affected by ASD in 2015 dollars exceeded the cost of hypertension and stroke (Pediatrics 2020;145:e20193447). For these reasons and so many others, it is vital that general pediatricians and other primary care providers (PCPs) are able to recognize, screen, refer, and care for the many comorbidities that affect children and adolescents with ASD. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Jane Oski Tags: The Editors' Perspectives Source Type: research

C difficile 2020
The study by Miranda-Katz et al from Kaiser Permanente Northern California approximates the true incidence of community-associated Clostridioides difficile diarrheal disease —13.7 cases per 100 000 per year for the population aged 1 to 17 years. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

It is time to standardize blood pressure measurements in the NICU
Currently the gold standard method for measuring blood pressure (BP) in neonates is through an indwelling intra-arterial catheter. The advances in the design of non-invasive BP monitoring, including oscillometric devices, has resulted in increasing usage of these tools in neonatal intensive care units (NICUs). Oscillometric devices use the amplitude of pulsations to estimate systolic and diastolic blood pressure. In practice, intra-arterial monitoring is currently reserved for unstable, critically ill neonates. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Reginald Washington Tags: The Editors' Perspectives Source Type: research

The persistent challenge of diabetic ketoacidosis in children and adolescents with type 1 diabetes
In this volume of The Journal, Kao et al report a retrospective cohort of youth with type 1 diabetes (T1D) with 11 years of data (from 2002-2012) on incidence trends of diabetic ketoacidosis (DKA) in children and adolescents with T1D in British Columbia, Canada. The authors found that among 2615 incident cases of T1D, 32.4% presented in DKA. Rates of DKA at diagnosis remained stable over 11 years with a range of 24.1 to 37.3 per 100 person-years. Similarly, rates of DKA in youth with diagnosed T1D were stable with a range of 4.9 to 7.7 per 100 person-years. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: David M. Maahs Tags: The Editors' Perspectives Source Type: research

Table of Contents
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Source Type: research

Masthead
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Source Type: research

Information for Readers
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Source Type: research

Caring for the Vaccine-Hesitant Family: Evidence-Based Alternatives  to Dismissal
Vaccine hesitancy is a growing public health threat. Recent data suggest that only one-half of children in the US are up-to-date for all recommended vaccines by 19-35  months, and more than one-third of children are on alternative or shot-limiting vaccine schedules.1 Measles infected 1282 Americans in 2019—the most cases since 1992—and the US nearly lost its measles elimination status.2 One in 40 kindergartners attends school with a nonmedical vaccine exempt ion, and many more kindergartners attend school underimmunized without plans to catch up. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Joshua T.B. Williams, Sean T. O'Leary, Abraham M. Nussbaum Tags: Commentary Source Type: research

Fetal Growth Restriction and Hypertension in the Offspring: Mechanistic Links and Therapeutic Directions
Hypertension, the leading cause of death among all cardiovascular disease (CVD) risk factors, affects>1.1 billion adults worldwide [1, 2]. Fetal growth restriction (FGR), generally defined as fetal growth (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Arvind Sehgal, Barbara T. Alexander, Janna L. Morrison, Andrew M. South Tags: Medical Progress Source Type: research

Axillary Calcification Due to Bacillus Calmette –Guérin Vaccination
A 10-month-old, fully vaccinated, infant boy was admitted to our hospital in rural Laos with respiratory distress that ultimately was diagnosed as due to beriberi.1 At the time of admission, a firm mass was noted in the right axilla (Figure  1) during routine physical examination. His parents reported that the mass was first palpable at about 4 months of age, had progressively increased in size until about a month before admission, and had since stabilized. A chest radiograph demonstrated a calcified right axillary mass with the typi cal appearance of lymph nodes (Figure 2, arrow). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Indi Trehan, Sonesavanh Mouayaxeng, Mark A. Nigogosyan Tags: Rediscovering the Physical Exam Source Type: research

Reconsidering asymptomatic bacteriuria and contamination as causes of bacteriuria without pyuria
Shaikh et  al performed a meta-analysis to determine the prevalence of asymptomatic bacteriuria in children.1 The clinical issue is whether a positive urine culture with a negative urinalysis represents a urinary tract infection (UTI) or asymptomatic bacteriuria. The authors calculate the rate of bacteriuria without pyuria (the working definition of asymptomatic bacteriuria) to be 0.18% in boys and 0.38% in girls. They compare these rates with the 5% rate of what they call “UTIs,” determine the rate of asymptomatic bacteriuria to be “at least an order of magnitude less than the prevalence of UTI, &rd...
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Kenneth B. Roberts, Ellen R. Wald Tags: Letter to the editor Source Type: research

The Impact of Sickle Cell Anemia and Mental Health on Preventive Care among Medicaid-Enrolled Children, 2005-2012
To examine mental health diagnoses, health care utilization, and receipt of age-appropriate preventive care, including antibiotic prophylaxis, hydroxyurea therapy, and transcranial Doppler (TCD) screenings among children with sickle cell anemia (SCA). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Jennifer P. Gondhi, Kevin J. Dombkowski, Eric L. Scott, Sarah L. Reeves Tags: Original Articles Source Type: research

Caring for the Vaccine Hesitant Family: Evidence-Based Alternatives to Dismissal
Vaccine hesitancy is a growing public health threat. Recent data suggest that only one-half of children in the U.S. are up-to-date for all recommended vaccines by 19-35 months, and over one third of children are on alternative or shot-limiting vaccine schedules.1 Measles infected 1,282 Americans in 2019 – the most cases since 1992 – and the US nearly lost its measles elimination status.2 One in 40 kindergartners attends school with a non-medical vaccine exemption, and many more kindergartners attend school under-immunized without plans to catch up. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2020 Category: Pediatrics Authors: Joshua T.B. Williams, Sean T. O ’Leary, Abraham M. Nussbaum Tags: Commentary Source Type: research

Serologic Evaluation of Celiac Disease for Patients Younger Than 2  Years of Age
The rising prevalence of pediatric celiac disease1,2 and the variability in presentation3 has prompted research and led to the evolution of published guidelines4-8 regarding recognition and accurate diagnosis. The diagnosis is challenging because celiac disease causes an array of symptoms or no symptoms at all. Also, histopathologic findings of duodenal biopsies consistent with celiac disease are seen in other common and uncommon pediatric intestinal diseases, such  as Crohn's disease, viral gastroenteritis, autoimmune enteropathy, and food protein–induced enteropathy,9-11 and although symptomatic response to gl...
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Daniel Mallon, Temara M. Hajjat Tags: Editorials Source Type: research

Children of frontline coronavirus disease-2019 warriors: our observations
We read with interest the article by Jiao et  al discussing the behavioral and emotional impact on children and adolescents imposed by the 2019 novel coronavirus disease (COVID-19) pandemic.1 Here we intend to share our personal observations regarding the difficulties and challenges faced by the children whose parents are frontline “warrior s” against COVID-19. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Souvik Dubey, Mahua Jana Dubey, Ritwik Ghosh, Subhankar Chatterjee Tags: Letter to the Editor Source Type: research

Reopening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-Coronavirus 2019 (COVID-19) Expectations, and Creative Solutions
In the US, 40% of families have school-aged children and in more than 90% of these households, at least 1 parent is employed outside the home. Schools play an important role in these working families.1 Yet, schools have been closed for approximately 2  months in an effort to curb the coronavirus 2019 (COVID-19) pandemic, and closing has had a profound influence on family health and well-being. When and how should they reopen? We approach these questions with limited data, and past epidemics provide little guidance for COVID-19. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Dan M. Cooper, Lisa Guay-Woodford, Bruce R. Blazar, Scott Bowman, Carrie L. Byington, Jeffrey Dome, Donald Forthal, Michael W. Konstan, Nathan Kuppermann, Robert I. Liem, Eduardo R. Ochoa, Brad H. Pollock, Olga Acosta Price, Bonnie W. Ramsey, Lainie Fried Tags: Commentary Source Type: research

Monilethrix
A 4-year-old boy was referred to our dermatology department for evaluation of a 3-year history of hair loss. His medical history was unremarkable. Examination revealed short, sparse, and brittle hair over the scalp and eyebrows, and he presented hyperkeratotic papules localized to the occipital scalp (Figure 1). His nails and teeth appeared normal. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Elisabeth G ómez Moyano, Angel Vera Casaño, Maria Dolores Fernandez Ballesteros Tags: Insights and Images Source Type: research

Trends in Anemia, Iron, Therapy, and Transfusion in Hospitalized Pediatric Patients with Inflammatory Bowel Disease
To evaluate trends in diagnosis and management of iron deficiency anemia using a large national children's hospital database in pediatric patients admitted with inflammatory bowel disease (IBD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Amanda E. Jacobson-Kelly, Joseph R. Stanek, Jacquelyn M. Powers, Jennifer L. Dotson, Sarah H. O'Brien Tags: Original Articles Source Type: research

Urticaria Pigmentosa
An otherwise healthy 4-month-old boy presented with persistent pruritic skin eruptions that had been present since the first week of life. His mother reported that the lesions repeatedly swelled up following oil massages. Cutaneous examination revealed multiple discrete tan-brown waxy papules and nodules ranging from 5 to 15  mm in diameter, involving the trunk (Figure, A). His face, acral areas, and mucosae were uninvolved. On firm stroking of a lesion, localized urticaria surrounded by an erythematous flare was elicited (positive Darier sign) (Figure, B). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Avik Panigrahi, Sayantani Chakraborty, Abheek Sil Tags: Rediscovering the Physical Exam Source Type: research

Blaschkoid Angioma Serpiginosum: A Clinico-Dermoscopic Diagnosis
An otherwise healthy 12-year-old boy presented with gradually progressive (over two years), asymptomatic reddish skin eruptions over his right upper limb and chest. There was no history of local trauma or bleeding from any site. No other family member had similar symptoms. Examination revealed bright-red grouped punctate macules and irregular patches arranged in a linear distribution, extending from the lateral aspect of right arm to the right pectoral area, following the lines of Blaschko [Figure, A]. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Avik Panigrahi, Sayantani Chakraborty, Sisir Das, Abheek Sil Tags: Rediscovering the Physical Exam Source Type: research

Re-Opening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-COVID Expectations, and Creative Solutions
In the US, 40% of families have school-aged children and in more than 90% of these households, at least one parent is employed outside the home. Schools play an important role in these working families.1 Yet schools have been closed for approximately 2 months in an effort to curb the COVID-19 pandemic and closing has had a profound influence on family health and wellbeing. When and how should they reopen? We approach these questions with limited data and past epidemics provide little guidance for COVID-19. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Dan M. Cooper, Lisa Guay-Woodford, Bruce R. Blazar, Scott Bowman, Carrie L. Byington, Jeffrey Dome, Donald Forthal, Michael W. Konstan, Nathan Kuppermann, Robert I. Liem, Eduardo R. Ochoa, Brad H. Pollock, Olga Acosta Price, Bonnie W. Ramsey, Lainie Fried Tags: Commentary Source Type: research

Serologic evaluation of celiac disease for patients under two years of age
The rising prevalence of pediatric celiac disease(1, 2) and the variability in presentation(3) has prompted research and led to the evolution of published guidelines(4-8) regarding recognition and accurate diagnosis. The diagnosis is challenging because celiac disease causes an array of symptoms or no symptoms at all. Also, histopathological findings of duodenal biopsies consistent with celiac disease are seen in other common and uncommon pediatric intestinal diseases such as Crohn ’s disease, viral gastroenteritis, autoimmune enteropathy, and food protein-induced enteropathy(9-11). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Daniel Mallon, Temara M. Hajjat Tags: Editorials Source Type: research

Reply
Dubey et al bring attention to the emotional and other difficulties of family members of the medical staff, especially those serving in the front line of the Covid-19 battle. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Massimo Pettoello-Mantovani, FuYong Jiao, Eli Somekh Tags: Letters to the Editor Source Type: research

Children of frontline COVID-19 warriors: Our observations
We read with interest the article by Jiao et al discussing the behavioral and emotional impact on children and adolescents imposed by the 2019 novel coronavirus disease(COVID-19) pandemic.1 Here we intend to share our personal observations regarding the difficulties and challenges faced by the children whose parents are frontline “warriors” against COVID-19. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2020 Category: Pediatrics Authors: Souvik Dubey, Mahua Jana Dubey, Ritwik Ghosh, Subhankar Chatterjee Tags: Letters to the Editor Source Type: research

Listen to Your Patients: A Diagnostic Clue
A newborn female child was delivered by cesarean after 37  weeks of gestation, complicated by intrauterine growth retardation. Her weight was 1610 g ( (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Fiorentino Grasso, Rita Genesio, Nicola Brunetti-Pierri Tags: Rediscovering the Physical Exam Source Type: research

Association between Transport Risk Index of Physiologic Stability in Extremely Premature Infants and Mortality or Neurodevelopmental Impairment at 18 to 24  Months
To examine the association between mortality or neurodevelopmental impairment at 18-24  months of corrected age and the Transport Risk Index of Physiologic Stability (TRIPS) score on admission to the neonatal intensive care unit (NICU) in extremely premature infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Beate Grass, Xiang Y. Ye, Edmond Kelly, Anne Synnes, Shoo Lee Tags: Original Articles Source Type: research

Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection
Infection with severe acute respiratory syndrome caused by the novel coronavirus 2019 (SARS-CoV-2) and resulting coronavirus disease 2019 (COVID-19) is a global pandemic.1 Pediatric cases have some peculiarities, such as milder clinical manifestations and different laboratory abnormalities.2 A systematic review on laboratory data identified 12 articles, with a total of 66 pediatric patients.3-15 Lymphopenia was found in only 3% of children, whereas lymphopenia often is described in adult patients. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Elisabetta Venturini, Giordano Palmas, Carlotta Montagnani, Elena Chiappini, Francesco Citera, Valeria Astorino, Sandra Trapani, Luisa Galli Tags: Letters to the editor Source Type: research

A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder
To evaluate whether umbilical cord blood (CB) infusion is safe and associated with improved social and communication abilities in children with autism spectrum disorder (ASD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Geraldine Dawson, Jessica M. Sun, Jennifer Baker, Kimberly Carpenter, Scott Compton, Megan Deaver, Lauren Franz, Nicole Heilbron, Brianna Herold, Joseph Horrigan, Jill Howard, Andrzej Kosinski, Samantha Major, Michael Murias, Kristin Page, Vinod K. Prasad Tags: Original Articles Source Type: research

Efficacy of a Primary Care-Based Intervention to Promote Parent-Teen Communication and Well-Being: A Randomized Controlled Trial
To evaluate the impact of a primary care-based, parent-directed intervention on changes in parent-teen communication, parental beliefs about adolescents, parent and adolescent well-being, adolescent distress, and adolescent positive affect from baseline to 2-month follow-up. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Victoria A. Miller, Karol Silva, Elizabeth Friedrich, Reyneris Robles, Carol A. Ford Tags: Original Articles Source Type: research

Listen to your patients - a diagnostic clue
A newborn female child was delivered by cesarean after 37 weeks of gestation, complicated by intrauterine growth retardation. Her weight was 1610 g ( (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Fiorentino Grasso, Rita Genesio, Nicola Brunetti-Pierri Tags: Rediscovering the Physical Exam Source Type: research

A Comparison of Strategies for Managing the Umbilical Cord at Birth in Preterm Infants
To evaluate the rates of practice, and the associations between different cord management strategies at birth [delayed cord clamping (DCC), umbilical cord milking (UCM) and early cord clamping (ECC)] and mortality or major morbidity, rates of blood transfusion, and peak serum bilirubin in a large national cohort of very preterm infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Walid El-Naggar, Jehier Afifi, Jon Dorling, Jaya Bodani, Zenon Cieslak, Rody Canning, Xiang Y. YE, Joan Crane, Shoo K. Lee, Prakesh S. Shah, Canadian Neonatal Network and the Canadian Preterm Birth Network Investigators Tags: Original Articles Source Type: research

Association between Transport Risk Index of Physiologic Stability (Trips) in Extremely Premature Infants and Mortality or Neurodevelopmental Impairment at 18 to 24 Months
To examine the association between mortality or neurodevelopmental impairment at 18-24 months of corrected age and the Transport Risk Index of Physiologic Stability (TRIPS) score on admission to the neonatal intensive care unit (NICU) in extremely premature infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2020 Category: Pediatrics Authors: Beate Grass, Xiang Y. Ye, Edmond Kelly, Anne Synnes, Shoo Lee Tags: Original Articles Source Type: research

Effects of the Global Coronavirus Disease-2019 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy Actions
In just a matter of weeks, the coronavirus disease-2019 (COVID-19) pandemic has led to huge societal public health and economic challenges worldwide. The clinical effects of COVID-19 on young children are uncertain when compared with older age groups, with lower morbidity and mortality rates and no conclusive evidence supporting transmission during pregnancy; however, there is emerging evidence of increasing rates of child hyperinflammatory shock.1-3 Research on the effects of prior pandemics and disasters clearly indicates that there will be both immediate and long-term adverse consequences for many children, with particu...
Source: The Journal of Pediatrics - May 18, 2020 Category: Pediatrics Authors: Hirokazu Yoshikawa, Alice J. Wuermli, Pia Rebello Britto, Benard Dreyer, James F. Leckman, Stephen J. Lye, Liliana Angelica Ponguta, Linda M. Richter, Alan Stein Tags: Commentary Source Type: research

Effects of the Global COVID-19 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy Actions
In just a matter of weeks, the COVID-19 pandemic has led to huge societal public health and economic challenges worldwide. The clinical effects of COVID-19 on young children are uncertain when compared with older age groups, with lower morbidity and mortality rates and no conclusive evidence supporting transmission during pregnancy, on the one hand, 1,2 but some emerging evidence of rising rates of child hyperinflammatory shock, on the other.3 Research on the effects of prior pandemics and disasters clearly indicates that there will be both immediate and long-term adverse consequences for many children, with particular ris...
Source: The Journal of Pediatrics - May 18, 2020 Category: Pediatrics Authors: Hirokazu Yoshikawa, Alice J. Wuermli, Pia Rebello Britto, Benard Dreyer, James F. Leckman, Stephen J. Lye, Liliana Angelica Ponguta, Linda M. Richter, Alan Stein Tags: Commentary Source Type: research

Performance of Pediatric Mortality Prediction Models in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis
To describe the performance of prognostic models for mortality or clinical deterioration events among hospitalized children developed or validated in low- and middle-income countries (LMICs). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2020 Category: Pediatrics Authors: Fiona Muttalib, Virginie Clavel, Lauren H. Yaeger, Vibhuti Shah, Neill KJ. Adhikari Tags: Original Articles Source Type: research

Effect of Blood Transfusions on Intermittent Hypoxic Episodes in a Prospective Study of Very Low Birth Weight Infants
To compare the number of intermittent hypoxia events before and after packed red blood cell (pRBC) and non-pRBC transfusions in very low birth weight infants, and to compare the time spent with saturations of ≤85% before and after transfusions in the same population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 15, 2020 Category: Pediatrics Authors: Kelley Z. Kovatis, Juliann M. Di Fiore, Richard J. Martin, Soraya Abbasi, Aasma S. Chaundhary, Stephen Hoover, Zugui Zhang, Haresh Kirpalani Tags: Original Articles Source Type: research

From Dysgammaglobulinemia to Autosomal-Dominant Activation-Induced Cytidine Deaminase Deficiency: Unraveling an Inherited Immunodeficiency  after 50 Years
This report illustrates the progress made over 6  decades in the characterization of primary immunodeficiencies, from immunochemistry to whole-exome sequencing. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 15, 2020 Category: Pediatrics Authors: Jehane Fadlallah, Loic Chentout, Bertrand Boisson, Aurore Pouliet, Cecile Masson, Florence Morin, Anne Durandy, Jean-Laurent Casanova, Eric Oksenhendler, Sven Kracker Tags: Brief Reports Source Type: research

Birth Weight and Weight Changes from Infancy to Early Childhood as Predictors of Body Mass Index in Adolescence
To assess the time point during infancy and early childhood at which greater than expected weight gain is associated with overweight in adolescence. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 15, 2020 Category: Pediatrics Authors: Katharina Stock, Rajini Nagrani, Nina Gande, Benoit Bernar, Anna Staudt, Peter Willeit, Ralf Geiger, Michael Knoflach, Ursula Kiechl-Kohlendorfer, Early Vascular Aging (EVA) Study Group Tags: Original Articles Source Type: research

Subclinical and Overt Newborn Opioid Exposure: Prevalence and First-Year Healthcare Utilization
To categorize newborn infants in Hamilton County, Ohio by late pregnancy fetal opioid exposure status and to assess their first-year healthcare utilization. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 15, 2020 Category: Pediatrics Authors: Zana Percy, Cole Brokamp, Jennifer M. McAllister, Patrick Ryan, Scott L. Wexelblatt, Eric S. Hall Tags: Original Article Source Type: research

Brown Plaque with Ripple Pattern on Nasolabial Fold
A 12-year-old boy presented with a 6-month history of asymptomatic brown plaques on his nasolabial fold that had not disappeared despite repetitive cleansing with soap and water. Physical examination showed a ripple pattern area of brown plaque with well-defined borders on his nasolabial fold (Figure  1). No other body part was involved and there were no systemic symptoms. A punch biopsy taken from his nasolabial fold showed papillomatosis of the epidermis associated with irregular acanthosis and prominent lamellar hyperkeratosis with intracorneal orthokeratotic whorls. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 14, 2020 Category: Pediatrics Authors: Yue-Tong Qian, Dong-Lai Ma Tags: Insights and Images Source Type: research

A Pilot Study of Mindfulness-Based Cognitive Therapy to Improve Well-Being for Health Professionals Providing Chronic Disease Care
To assess the efficacy of mindfulness-based cognitive therapy delivered onsite during work hours in reducing stress and improving well-being in an interdisciplinary chronic care health care team. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 14, 2020 Category: Pediatrics Authors: Elizabeth Hente, Richard Sears, Sian Cotton, Harini Pallerla, Christopher Siracusa, Stephanie Spear Filigno, Thomas Boat Tags: Original Articles Source Type: research

Prenatal Maternal Objective and Subjective Stress Exposures and Rapid Infant Weight Gain
To evaluate the associations between 3 prenatal stress exposures and rapid infant weight gain. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 14, 2020 Category: Pediatrics Authors: Jennifer N. Felder, Elissa Epel, Michael Coccia, Alana Cordeiro, Barbara Laraia, Nancy Adler, Kimberly Coleman-Phox, Nicole R. Bush Tags: Original Articles Source Type: research

Vaccine Hesitancy and Low Immunization Rates in Children  with Down Syndrome
To determine the prevalence of vaccine hesitancy and refusal among parents of children with Down syndrome and to determine how well the Parent Attitudes about Childhood Vaccines Survey (PACV) is associated with vaccine receipt among children with Down syndrome. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 14, 2020 Category: Pediatrics Authors: Diane L. Langkamp, Anna Dusseau, Miraides F. Brown Tags: Original Articles Source Type: research

Treating Center Volume and Congenital Diaphragmatic Hernia Outcomes in California
To examined outcomes for infants born with congenital diaphragmatic hernias (CDH), according to specific treatment center volume indicators. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 14, 2020 Category: Pediatrics Authors: Jordan C. Apfeld, Zachary J. Kastenberg, Alexander T. Gibbons, Suzan L. Carmichael, Henry C. Lee, Karl G. Sylvester Tags: Original Articles Source Type: research