50 Years Ago in The Journal of Pediatrics
Schaller J, Beckwith B, Wedgwood RJ. Hepatic involvement in juvenile rheumatoid arthritis. J Pediatr 1970;77:203-10. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Batul Kaj-Carbaidwala Source Type: research

50 Years Ago in The Journal of Pediatrics
Jayalakshmi P, McNair Scott T, Tucker H, Schaffer D. Infantile nystagmus: a prospective study of spasmus nutans, congenital nystagmus, and unclassified nystagmus of infancy. J Pediatr 1970;77:177-87. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Shannon Beres Source Type: research

Evaluation of Chest Radiographs of Children with Newly Diagnosed Acute  Lymphoblastic Leukemia
To evaluate the diagnostic yield of baseline chest radiographs (CXRs) of children with acute lymphoblastic leukemia (ALL). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Wesley T. Smith, Kenneth T. Shiao, Elena Varotto, Yinmei Zhou, Mayuko Iijima, Doralina L. Anghelescu, Cheng Cheng, Sima Jeha, Ching-Hon Pui, Sue C. Kaste, Hiroto Inaba Tags: Original Article Source Type: research

Elevated Interleukin-6 Levels Predict Clinical Worsening in Pediatric Pulmonary Arterial Hypertension
To assess whether circulating interleukin-6 (IL-6) is associated with measures of disease severity and clinical worsening in pediatric pulmonary arterial hypertension (PAH). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Jenny Y. Chen, Megan Griffiths, Jun Yang, Melanie K. Nies, Rachel L. Damico, Catherine E. Simpson, R. Dhananjay Vaidya, Stephanie Brandal, D. Dunbar Ivy, Eric D. Austin, William C. Nichols, Michael W. Pauciulo, Katie Lutz, Erika B. Rosenzweig, Russel Hirs Tags: Original Article Source Type: research

Early Neonatal Oxygen Exposure Predicts Pulmonary Morbidity and Functional Deficits at 1  Year
To evaluate the predictive value of cumulative oxygen exposure thresholds over the first 2 postnatal weeks, linking them to bronchopulmonary dysplasia (BPD) and 1-year pulmonary morbidity and lung function in extremely low gestational age newborns. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Andrew M. Dylag, Hannah G. Kopin, Michael A. O'Reilly, Hongyue Wang, Stephanie D. Davis, Clement L. Ren, Gloria S. Pryhuber Tags: Original Article Source Type: research

The Challenge of Risk Stratification of Infants Born Preterm in the Setting of Competing and Disparate Healthcare Outcomes
Clinical decision-making regarding the use of medical therapies in infants born preterm requires consideration of clinical benefits and adverse effects based on individualized risk-stratification. Therapies are implemented when the burden of the disease state and the certainty of the diagnosis exceed the burden of adverse effects from the intervention. Standardization of clinical decision-making with accurate, actionable risk-stratification tools has advanced care quality in newborn infants. For example, early-onset sepsis risk calculators that integrate multiple relevant clinical characteristics have reduced the use of an...
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Halana V. Whitehead, Christopher C. McPherson, Zachary A. Vesoulis, Barbara A. Cohlan, Rakesh Rao, Barbara B. Warner, F. Sessions Cole Tags: Commentary Source Type: research

Body Image Dissatisfaction among Pediatric Patients with Inflammatory Bowel Disease
To determine risk factors for body image dissatisfaction among pediatric patients with inflammatory bowel disease (IBD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Jennifer D. Claytor, Bharati Kochar, Michael D. Kappelman, Millie D. Long Tags: Original Article Source Type: research

Muscle Mass Is Linked to Liver Disease Severity in Pediatric Nonalcoholic  Fatty Liver Disease
To investigate the association between muscle mass and liver disease severity in pediatric patients with non-alcoholic fatty liver disease (NAFLD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Toshifumi Yodoshi, Sarah Orkin, Ana-Catalina Arce Clachar, Kristin Bramlage, Qin Sun, Lin Fei, Andrew F. Beck, Stavra A. Xanthakos, Andrew T. Trout, Marialena Mouzaki Tags: Original Article Source Type: research

A Toddler with Sudden Scrotal Swelling
A 2-year-old boy was referred to the Emergency Department with an abrupt onset of scrotal swelling and redness. The parents did not report local trauma, fever, abdominal pain, or dysuria. The patient was afebrile and well appearing. Physical examination revealed thickened and hyperemic skin of the bilateral scrotal sac extending to the groin and perianal region (Figure  1, A and B). Palpation evoked mild scrotal pain. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Andrea Trombetta, Andrea Taddio, Flora Maria Murru, Irene Berti Tags: Rediscovering the Physical Exam Source Type: research

Editors' Response
We take this opportunity to comment on the letter to the editor from Drs Roberts and Wald, questioning the validity of the analysis and conclusion of the manuscript by Shaikh et  al, and the authors' response. We believe that the analysis performed by Shaikh et al is sound and stand by the decision of The Journal to publish their study. We also choose to publish the letter and response to further enrich the deliberations of our readers. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Thomas R. Welch, Sarah S. Long Tags: Letter to the Editor Source Type: research

Effects of Neonatal Hyperglycemia on Retinopathy of Prematurity and Visual Outcomes at 7  Years of Age: A Matched Cohort Study
To determine whether neonatal hyperglycemia is associated with retinopathy of prematurity (ROP), visual outcomes, and ocular growth at 7  years of age. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Myra Leung, Joanna Black, Frank H. Bloomfield, Greg D. Gamble, Jane E. Harding, Yannan Jiang, Tanya Poppe, Benjamin Thompson, Anna C. Tottman, Trecia A. Wouldes, Jane M. Alsweiler, PIANO study group Tags: Original Article Source Type: research

A picture of severe COVID-19 in US children and youth emerges
The reports of Chao et al and DeBiasi et al from the Children's Hospital at Montefiore in New York City (NYC) and Children's National Hospital in Washington, DC (DC) provide their SARS-CoV-2 experience over 4- and 6-week periods, respectively, beginning on March 15, 2020. Although SARS-CoV-2 generally has been said to be a mild infection in the pediatric age group, a picture of severe COVID-19 in US children and youth emerges through these reports. Together, 91 hospitalized patients with 22 critically ill are reported, with demographic and other patient characteristics compared between groups. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

Thanking families for research participation
For many years, neonatologists and endocrinologists have debated the question: “What is a normal blood glucose level in the first days after birth?” In this volume of The Journal of Pediatrics, Harris et al publish results of the GLOW study that was carefully designed to provide high quality answers to this question. The authors found that glucose levels stabilized at adul t levels by 4 days of age, but before then, glucose levels (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Raye-Ann deRegnier Tags: The Editors' Perspectives Source Type: research

General anesthesia adds to the cognitive sequelae of childhood cancer
The impact of the total number of administrations and the cumulative dosage of anesthetics and sedatives on the developing brain is not a new topic for readers of The Journal (J Pediatr 2019;204:285 –90). In this volume, Jacola et al report the effects of anesthesia exposure in 111 children with medulloblastoma from a retrospective, secondary analysis of patients at St. Jude Children's Research Hospital enrolled on a multisite clinical trial (https://clinicaltrials.gov/ct2/show/NCT00085202). The children were all treated with surgical resection of tumor, followed by radiotherapy and chemotherapy. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Paul G. Fisher Tags: The Editors' Perspectives Source Type: research

Paradoxical hypertension
A host of physiologic factors contribute to the maintenance of blood pressure. Of these, intravascular volume is perhaps the most important. Thus, when confronted with low or elevated blood pressure, clinicians rightly consider reduced or elevated intravascular volume, respectively. Volume expansion is usually a correct response to hypotension; similarly, volume expansion in the context of hypertension is counter intuitive. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Thomas R. Welch Tags: The Editors' Perspectives Source Type: research

Skin to skin care: More than meets the eye
Skin-to-skin care, often referred to as kangaroo care, was developed decades ago in South America as a supplement to the care of the preterm infant —primarily to provide warmth and facilitate earlier release from the hospital. Since then, skin-to-skin care has been associated with improved breastfeeding, reduced maternal stress, and improved maternal attachment and post-discharge confidence in the care of her preterm infant. In a previous vol ume of The Journal, Sehgal et al provide additional rationale indicating that skin-to-skin care directly improves physiologic stability of the preterm infant. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Robin H. Steinhorn Tags: The Editors' Perspectives Source Type: research

Subtle forms of vaccine hesitancy affecting children and adolescents are unreasonable and risky
Vaccine refusal and hesitancy have clear adverse effects on the nonvaccinated individual as well as on the community. Related research has been performed largely in the general pediatric population. Two studies have focused their lenses on subtle forms of vaccine hesitancy, in special groups —children with Down syndrome and the general adolescent population. In this volume of The Journal Langkamp et al administered the Parental Attitudes about Childhood Vaccines Survey (PACV) (a validated tool for the general pediatric population) to 55 parents of children ≤8 years of age attending the Down Syndrome Clinic at Akro...
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

Table of Contents
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Source Type: research

Masthead
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Source Type: research

Information for Readers
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Source Type: research

Presentation of Severe Acute Respiratory Syndrome-Coronavirus 2 Infection as Cholestatic Jaundice in Two Healthy Adolescents
We describe 2 adolescents with cholestasis and hepatitis with mild presentation of severe acute respiratory syndrome-coronavirus 2 lacking typical symptoms. Our intention is to raise index of suspicion for testing and protective equipment use. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Adriana Perez, Debora Kogan-Liberman, Shari Sheflin-Findling, Aileen Raizner, Kanya L. Ahuja, Nadia Ovchinsky Tags: Brief Reports Source Type: research

Association of early antibiotic exposure and necrotizing enterocolitis: causality or confounding bias?
We read with great interest the report by Li et  al that compared the incidence of necrotizing enterocolitis (NEC) in infants with very low birth weight according to early antibiotic treatment.1 We would like to raise the question: association of early antibiotic exposure and NEC: causality or confounding bias? (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Mathilde Letouzey, Laurence Foix-L'H élias, Pascal Boileau, Elsa Lorthe Tags: Letter to the Editor Source Type: research

Behavioral Functioning and Quality of Life in South African Children Living with HIV on Antiretroviral Therapy
Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 073977, HD 073952). The authors declare no conflicts of interest. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Stephanie Shiau, Henry Evans, Renate Strehlau, Yanhan Shen, Megan Burke, Afaaf Liberty, Ashraf Coovadia, Elaine J. Abrams, Michael T. Yin, Avy Violari, Louise Kuhn, Stephen M. Arpadi Tags: Brief Reports Source Type: research

Presentation of SARS-CoV-2 Infection As Cholestatic Jaundice in Two Healthy Adolescents
We describe two adolescents with cholestasis and hepatitis with mild presentation of SARS-CoV-2 lacking typical symptoms. Our intention is to raise index of suspicion for testing and protective equipment use. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Adriana Perez, Debora Kogan-Liberman, Shari Sheflin-Findling, Aileen Raizner, Kanya L. Ahuja, Nadia Ovchinsky Tags: Brief Reports Source Type: research

Delayed vs Immediate Cord Clamping Changes Oxygen Saturation and Heart Rate Patterns in the First Minutes after Birth
To build SpO2 and HR percentiles for the first ten minutes after birth in term infants born after an uneventful gestation, vaginal delivery, and delayed cord clamping for ≥ 60 seconds, and to compare our results with previous ones constructed after immediate cord clamping. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: Celia Padilla-S ánchez, Susana Baixauli-Alacreu, Antonio José Cañada-Martínez, Álvaro Solaz-García, Ma José Alemany-Anchel, Máximo Vento Torres Tags: Original Articles Source Type: research

Association of early antibiotic exposure and NEC: causality or confounding bias?
We read with great interest the report by Li et al [1] that compared the incidence of necrotizing enterocolitis (NEC) in very low birth weight infants according to early antibiotic treatment. We would like to raise the question: association of early antibiotic exposure and NEC: causality or confounding bias? (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2020 Category: Pediatrics Authors: M. Letouzey, L. Foix-L ’Hélias, P. Boileau, E. Lorthe Tags: Letters to the Editor Source Type: research

Frequency of Multifocal Disease and Pyogenic Arthritis of the Hip in Infants with Osteoarticular Infection in Three Neonatal Intensive Care Units
To describe the clinical features of osteoarticular infection in infants cared for in neonatal intensive care units (NICUs) and to assess the presence of multifocal infection. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 21, 2020 Category: Pediatrics Authors: Lorry G. Rubin, Jiwoong Shin, Ishminder Kaur, Oded Scheuerman, Itzhak Levy, Sarah S. Long Tags: Original Articles Source Type: research

Effect of Cognitive and Physical Rest on Persistent Postconcussive Symptoms following a Pediatric Head Injury
To evaluate the effect of cognitive and physical rest on persistent postconcussive symptoms in a pediatric population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Jeremy M. Root, Maegan D. Sady, Jiaxiang Gai, Christopher G. Vaughan, Ponda J. Madati Tags: Original Articles Source Type: research

Trends in Pediatric Emergency Department Utilization after Institution of Coronavirus Disease-19 Mandatory Social Distancing
We conducted a descriptive cross-sectional study of pediatric emergency healthcare use during the onset of severe acute respiratory syndrome coronavirus 2 pandemic after a state-wide stay-at-home order. Our study demonstrated decreased volume, increased acuity, and generally consistent chief complaints compared with the prior 3  years (2017 through 2019). Ingestions became a significantly more common chief complaint in 2020. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Barbara H. Chaiyachati, Atu Agawu, Joseph J. Zorc, Fran Balamuth Tags: Brief Reports Source Type: research

Effect of Cognitive and Physical Rest on Persistent Post-Concussive Symptoms Following a Pediatric Head Injury
To evaluate the effect of cognitive and physical rest on persistent post-concussive symptoms (PPCS) in a pediatric population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: J.M. Root, M.D. Sady, J. Gai, C.G. Vaughan, P.J. Madati Tags: Original Articles Source Type: research

A Midline Nasal Mass in a Term Neonate
A term infant with pneumothorax was admitted to the neonatal unit for respiratory support after birth. On examination the infant had a skin coloured mass extending from the nasal septum, occluding the right nasal aperture (Figure, 1). The pneumothorax resolved but the respiratory distress persisted with desaturations, particularly during feeding. A nasopharyngeal airway was inserted. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: A. Jenkinson, M. Sheehan, R. Mehanna, L. McCarthy Tags: Rediscovering the Physical Exam Source Type: research

Prevalence and Utility of Low Mean Corpuscular Volume in Infants Admitted to the Neonatal Intensive Care Unit
To determine the prevalence of low mean corpuscular volume (MCV) in newborn infants admitted to the Neonatal Intensive Care Unit (NICU) and to assess low MCV as a diagnostic test for alpha thalassemia. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Rose Guo, Dana Neumann, Margaret Lafferty, Rupsa Boelig, Brandi Bell-Carey, Caroline Edwards, Jay S. Greenspan, Richard Derman, Zubair H. Aghai Tags: Original Articles Source Type: research

Pediatric Feeding Disorder: A Nationwide Prevalence Study
To assess the prevalence of pediatric feeding disorder (PFD) in U.S. children. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Karlo Kovacic, Lisa E. Rein, ScM, Pradeep Bhagavatula, Sruthi Kommareddy, Aniko Szabo, Praveen S. Goday Tags: Original Articles Source Type: research

Trends in Pediatric Emergency Department Utilization after Institution of COVID-19 Mandatory Social Distancing
We conducted a descriptive cross-sectional study of pediatric emergency healthcare utilization during the onset of SARS-CoV-2 pandemic after a state-wide stay-at-home order. Our study demonstrated decreased volume, increased acuity, and generally consistent chief complaints compared with the prior 3 years (2017 through 2019). Ingestions became a significantly more common chief complaint in 2020. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Barbara H. Chaiyachati, Atu Agawu, Joseph J. Zorc, Fran Balamuth Tags: Brief Reports Source Type: research

Reversible Myelofibrosis in Pediatric Renal Osteodystrophy
A 9-year-old female with no medical care for 3 years presented with recurrent emesis, epistaxis, and pallor. Laboratory evaluation showed renal failure with blood urea nitrogen 216 mg/dL and serum creatinine of 17.5 mg/dL. Hematologic workup showed severe normocytic anemia with hemoglobin concentration of 4.3 g/dL and an initial platelet count of 108 x 109/L that decreased to 60 x 109/L over 5 days. Her total white blood cell count was normal, but she had mild lymphopenia (1.3 X 109/L). Parathyroid hormone (PTH) levels were markedly elevated at 1600 pg/mL (normal range 15-87). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 20, 2020 Category: Pediatrics Authors: Anthony Sabulski, Erica Hughley, Edward J. Nehus, David D. Grier, Omar Niss Tags: Insights and Images Source Type: research

Celiac Disease in Children with Functional Constipation: A School-Based Multicity Study
To determine whether children in the community with functional constipation have increased prevalence of celiac disease. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 19, 2020 Category: Pediatrics Authors: Amanda C. Fifi, Carlos Velasco-Benitez, Miguel Saps Tags: Original Articles Source Type: research

Association between Neonatal Intensive Care Unit Admission and Supine Sleep Positioning, Breastfeeding, and Postnatal Smoking among Mothers of Late Preterm Infants
To evaluate the association between neonatal intensive care unit (NICU) admission and breastfeeding practices, infant supine sleep positioning, and postnatal smoking among mothers of late preterm infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 19, 2020 Category: Pediatrics Authors: Kathleen E. Hannan, Ruben A. Smith, Wanda D. Barfield, Sunah S. Hwang Tags: Original Articles Source Type: research

Celiac Disease in Children with Functional Constipation: A School Based Multicity Study.
To determine if children in the community with functional constipation have increased prevalence of celiac disease (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 19, 2020 Category: Pediatrics Authors: Amanda C. Fifi, Carlos Velasco-Benitez, Miguel Saps Tags: Original Articles Source Type: research

Association between NICU Admission and Supine Sleep Positioning, Breastfeeding, and Postnatal Smoking among Mothers of Late Preterm Infants
To evaluate the association between neonatal intensive care unit (NICU) admission and breastfeeding practices, infant supine sleep positioning, and postnatal smoking among mothers of late preterm infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 19, 2020 Category: Pediatrics Authors: Kathleen E. Hannan, Ruben A. Smith, Wanda D. Barfield, Sunah S. Hwang Tags: Original Articles Source Type: research

Early antibiotic therapy and adverse outcomes in preterm infants: Time for a trial!
For decades, antibiotics have been prescribed after delivery to preterm infants cared for in the neonatal intensive care unit. Given the risks of early-onset sepsis, particularly during the peak of group B streptococcal disease, a “better safe than sorry” approach to empiric antibiotics became commonplace. Like Thetis dipping her newborn Achilles into the river Styx to confer invulnerability, neonatologists would routinely administer ampicillin and gentamicin for days or even weeks, often in the absence of any objective e vidence for infection. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 18, 2020 Category: Pediatrics Authors: Joseph B. Cantey Tags: Editorials Source Type: research

Relationships between Physiologic and Neuropsychologic Functioning after Fontan
To investigate potential relationships between neuropsychologic functioning and cardiac, gastroenterologic/hepatologic, and pulmonary complications in the single ventricle heart disease (SVHD) post-Fontan population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 17, 2020 Category: Pediatrics Authors: Kelly R. Wolfe, Deborah R. Liptzin, Dania Brigham, Sarah L. Kelly, Carey Rafferty, Megan Albertz, Adel K. Younoszai, Michael V. Di Maria Tags: Original Articles Source Type: research

Relationships Between Physiological and Neuropsychological Functioning After Fontan
To investigate potential relationships between neuropsychological functioning and cardiac, gastroenterologic/hepatologic, and pulmonary complications in the single ventricle heart disease (SVHD) post-Fontan population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 17, 2020 Category: Pediatrics Authors: Kelly R. Wolfe, Deborah R. Liptzin, Dania Brigham, Sarah L. Kelly, Carey Rafferty, Megan Albertz, Adel K. Younoszai, Michael V. Di Maria Tags: Original Articles Source Type: research

Optimizing Duration of Empiric Management of Suspected Central Line-Associated Bloodstream Infections (CLABSIs) in Pediatric Intestinal Failure Patients
To assess whether a 24-hour length of hospitalization and empiric antibiotic therapy to exclude central line-associated bloodstream infection (CLABSI) in children with intestinal failure is potentially as safe as 48 hours, which is the duration most commonly used but not evidence based. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 17, 2020 Category: Pediatrics Authors: Gillian L. Fell, Bennet S. Cho, Lorenzo Anez-Bustillos, Duy T. Dao, Meredith A. Baker, Prathima Nandivada, Alison A. O ’Loughlin, Alexis P. Hurley, Paul D. Mitchell, Shawn Rangel, Kathleen M. Gura, Mark Puder Tags: Original Articles Source Type: research

Child Care in the Time of Coronavirus Disease-19: A Period of Challenge and Opportunity
The early care and education of young children, more commonly known as child care, is a ubiquitous experience in the US across geographies and socioeconomic levels. Nationally, more than 12 million children —or nearly two-thirds of children under 5 years of age—regularly participate in out-of-home care, making early care and education a $47.2 billion industry with a workforce of more than 1.5 million child care providers.1-3 Early care and education involves children from birth through kindergarte n entry, a time when organized, group care, including child care centers, family child care homes, preschool, ...
Source: The Journal of Pediatrics - July 16, 2020 Category: Pediatrics Authors: Andrew N. Hashikawa, Jill M. Sells, Peter M. DeJonge, Abbey Alkon, Emily T. Martin, Timothy R. Shope Tags: Commentary Source Type: research

Child Care in the Time of COVID-19: A Period of Challenge and Opportunity.
The early care and education of young children, more commonly known as child care, is a ubiquitous experience in the United States (US) across geographies and socioeconomic levels. Nationally, over 12 million children —or nearly two-thirds of children under five years-of-age—regularly participate in out-of-home care, making ECE a 47.2 billion dollar industry with a workforce of over 1.5 million child care providers.1-3 ECE involves children from birth through kindergarten entry, a time when organized, group c are, including child care centers, family child care homes, preschool, and Head Start programs, represe...
Source: The Journal of Pediatrics - July 16, 2020 Category: Pediatrics Authors: Andrew Hashikawa, Jill Sells, Peter DeJonge, Abbey Alkon, Emily T. Martin, Timothy R. Shope Tags: Commentary Source Type: research

Death After Birth Asphyxia in the Cooling Era
P.W. receives research grant funding from the FRSQ Clinical Research Scholar Career Awards Junior 2 and a CIHR Project Grant. The study sponsors had no involvement in the study design; the collection, analysis, and interpretation of data; the writing of the report; or the decision to submit the paper for publication. The authors declare no conflicts of interest. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 16, 2020 Category: Pediatrics Authors: Fatema Al Amrani, Eric Racine, Michael Shevell, Pia Wintermark Tags: Brief Reports Source Type: research

Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with Coronavirus Disease 2019 (COVID-19) in New York City
To describe the clinical manifestations and outcomes of critically ill children with coronavirus disease-19 (COVID-19) in New York City. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 15, 2020 Category: Pediatrics Authors: Kim R. Derespina, Shubhi Kaushik, Anna Plichta, Edward E. Conway, Asher Bercow, Jaeun Choi, Ruth Eisenberg, Jennifer Gillen, Anita I. Sen, Claire M. Hennigan, Lillian M. Zerihun, Sule Doymaz, Michael A. Keenaghan, Stephanie Jarrin, Franscene Oulds, Manoj Tags: Original Articles Source Type: research

The Economic Impact of Donor Milk in the Neonatal Intensive Care Unit
To assess the cost-effectiveness of mother's own milk supplemented with donor milk  vs mother's own milk supplemented with formula for infants of very low birth weight in the neonatal intensive care unit (NICU). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 15, 2020 Category: Pediatrics Authors: Tricia J. Johnson, Andrew Berenz, Jennifer Wicks, Anita Esquerra-Zwiers, Kelly S. Sulo, Megan E. Gross, Jennifer Szotek, Paula Meier, Aloka L. Patel Tags: Original Articles Source Type: research

Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City
To describe the clinical manifestations and outcomes of critically ill children with coronavirus disease-19 (COVID-19) in New York City. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 15, 2020 Category: Pediatrics Authors: Kim R. Derespina, Shubhi Kaushik, Anna Plichta, Edward E. Conway, Asher Bercow, Jaeun Choi, Ruth Eisenberg, Jennifer Gillen, Anita I. Sen, Claire M. Hennigan, Lillian M. Zerihun, Sule Doymaz, Michael A. Keenaghan, Stephanie Jarrin, Franscene Oulds, Manoj Tags: Original Articles Source Type: research

Barriers to Pretransplant Immunization: A Qualitative Interview Study of Pediatric Solid Organ Transplant Stakeholders
To describe the experiences and beliefs of pediatric transplant stakeholders regarding factors that contribute to low pretransplant immunization rates. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 14, 2020 Category: Pediatrics Authors: Amy G. Feldman, Rebekah Marsh, Allison Kempe, Megan A. Morris Tags: Original Articles Source Type: research