Swollen Ankle with a Hole: Brodie Abscess
A 12-year-old boy presented with a 1-year history of  painful swelling of the left ankle. The pain was recurrent, exacerbated by mechanical loading, occasionally nocturnal, and responsive to nonsteroidal anti-inflammatory drugs. The patient was afebrile. Physical examination revealed a tender, nonfluctuating swelling of the left distal tibia, withou t flare or erythema; the range of motion was painfully limited. Inflammatory markers and complete blood count were normal. Tuberculin skin test resulted negative. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 28, 2021 Category: Pediatrics Authors: Benedetta Bossini, Prisca Da Lozzo, Ester Conversano, Flora Maria Murru, Sara Della Paolera, Andrea Taddio, Alberto Tommasini Tags: Insights and Images Source Type: research

Swollen Ankle With a Hole: Brodie ’s Abscess
A 12-year-old boy presented with a 1-year history of painful swelling of the left ankle. The pain was recurrent, exacerbated by mechanical loading, occasionally nocturnal, and responsive to NSAIDs. The patient was afebrile. Physical examination revealed a tender, non-fluctuating swelling of the left distal tibia, without flare or erythema; the range of motion was painfully limited. Inflammatory markers and complete blood count were normal. Tuberculin skin test resulted negative. Plain radiographs showed a longitudinal lytic lesion extending across the growth plate of the left distal tibial metaphysis, highly suggestive of ...
Source: The Journal of Pediatrics - May 28, 2021 Category: Pediatrics Authors: Benedetta Bossini, Prisca Da Lozzo, Ester Conversano, Flora Maria Murru, Sara Della Paolera, Andrea Taddio, Alberto Tommasini Tags: Insights and Images Source Type: research

Efficacy and Safety of IV Sildenafil in the Treatment of Newborn Infants with, or at Risk of, Persistent Pulmonary Hypertension of the Newborn (PPHN): A Multicenter, Randomized, Placebo-Controlled Trial
To investigate the efficacy and safety of sildenafil added to inhaled nitric oxide (iNO) for newborn infants with persistent pulmonary hypertension of newborn (PPHN) or hypoxic respiratory failure (HRF) at risk of PPHN. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 27, 2021 Category: Pediatrics Authors: Christine M. Pierce, Min H. Zhang, Baldvin Jonsson, Dinu Iorga, Narayan Cheruvu, Cecile C. Balagtas, Robin H. Steinhorn Tags: Original Article Source Type: research

Efficacy and Safety of IV Sildenafil in the Treatment of Newborn Infants With, or at Risk of Persistent Pulmonary Hypertension of the Newborn (PPHN): A Multicenter, Randomized, Placebo-Controlled Trial
Data sharing statement: Upon request, and subject to certain criteria, conditions, and exceptions (see https://www.pfizer.com/science/clinical-trials/trial-data-and-results for more information), Pfizer will provide access to individual de-identified participant data from Pfizer-sponsored global interventional clinical studies conducted for medicines, vaccines, and medical devices: (1) for indications that have been approved in the United States and/or European Union; or (2) in programs that have been terminated (i.e., development for all indications has been discontinued). Pfizer will also consider requests for the protoc...
Source: The Journal of Pediatrics - May 27, 2021 Category: Pediatrics Authors: Christine M. Pierce, Min H. Zhang, Baldvin Jonsson, Dinu Iorga, Narayan Cheruvu, Cecile C. Balagtas, Robin H. Steinhorn Tags: Original Articles Source Type: research

Median raphe cysts: why surgical excision should be performed in childhood
Bayne et  al reported the clinical presentation of the uncommon entity of a median raphe cyst of the perineum.1 They outlined the embryologic fusion as a major pathogenetic mechanism, the benign course of the abnormality, and proposed complete surgical excision to avoid recurrence.1 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 26, 2021 Category: Pediatrics Authors: Xenophon Sinopidis, Maria Athanasopoulou, Eleni Kourea, George Georgiou Tags: Letters to the Editor Source Type: research

Median raphe cysts-why surgical excision should be performed in childhood.
Bayne et al reported the clinical presentation of the uncommon entity of a median raphe cyst of the perineum.1 They outlined the embryologic fusion as a major pathogenetic mechanism, the benign course of the abnormality, and proposed complete surgical excision to avoid recurrence.1 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 26, 2021 Category: Pediatrics Authors: Xenophon Sinopidis, Maria Athanasopoulou, Eleni Kourea, George Georgiou Tags: Letters to the Editor Source Type: research

Effects of N95 Mask Use on Pulmonary Function in Children
To assess whether the use of an N95 mask by children was associated with episodes of desaturation or respiratory distress. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 24, 2021 Category: Pediatrics Authors: Riccardo Lubrano, Silvia Bloise, Alessia Marcellino, Claudia Proietti Ciolli, Alessia Testa, Enrica De Luca, Anna Dilillo, Saverio Mallardo, Sara Isoldi, Vanessa Martucci, MariaTeresa Sanseviero, Emanuela Del Giudice, Concetta Malvaso, Claudio Iacovelli, Tags: Original Articles Source Type: research

Youth involved in the justice system: Emergency department screening and health promotion
Youth involved in the justice system have significant health comorbidities including high rates of mental health disorders, substance use disorders and chronic health problems.1,2 Moreover, justice-involved youth tend to live in disadvantaged, urban neighborhoods, and evidence poor educational attainment with high rates of suspension and drop-outs from school.3 As such, health care providers, advocates and researchers universally recognize the importance of connecting justice-involved youth to needed services for mental health, substance use and medical treatment. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 22, 2021 Category: Pediatrics Authors: Lauren Magee, Matthew C. Aalsma Tags: Editorials Source Type: research

50 Years Ago in The Journal of Pediatrics
Melish ME, Glasgow LA. Staphylococcal scalded skin syndrome: the expanded clinical syndrome. J Pediatr 1971;78:958-67. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Shashi Kant Dhir, Piyush Gupta Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Pincus T, Hughes GRV, Pincus D, Tina LU, Bellanti JA. Antibodies to dsDNA in childhood systemic lupus erythematosus. J Pediatr 1971;78:981-4. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Limor Ashkenazi, Philip J. Hashkes Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Kuhns LR, Poznanski AK. Endotracheal tube position in the infant. J Pediatr 1971;78:991-6. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Lauren E. Boudreau, James F. Padbury Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Roe TF, Hallatt JG, Donnell GN, Ng WG. Childbearing by a galactosemic woman. J Pediatr 1971;78:1026-30. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Runar Almaas, Ola Didrik Saugstad Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Drash A. Diabetes mellitus in childhood: a review. J Pediatr 1971;78:919-41. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Jennifer M. Ikl é, David M. Maahs Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Van den Berg BJ, Yerushalmy J. Studies on convulsive disorders in young children. II. Intermittent phenobarbital prophylaxis and recurrence of febrile convulsions. J Pediatr 1971;78:1004-12. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Aparna Polavarapu, Solomon L. Mosh é Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Greensher H, Mofenson C, Borofsky L, Sharma R. Lumbar puncture in the neonate: a simplified technique. J Pediatr 1971;78:1034-5. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: William Bonadio, Joseph Decristofaro Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Orr ER, Riley HD Jr. Sporotrichosis in childhood: report of ten cases. J Pediatr 1971;78:951-7. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: John Verrinder Veasey, Marco Aur élio P. Sáfadi Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
McCracken GH. Changing pattern of the antimicrobial susceptibilities of Escherichia coli in neonatal infections. J Pediatr 1971;78:942-7. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Stephanie Popofsky, Rebecca Pellett Madan Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Swanson SL, Santen RJ, Smith DW. Multiple lentigines syndrome: new findings of hypogonadotrophism, hyposmia, and unilateral renal agenesis. J Pediatr 1951;48:1037-9. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Sarah E. Sheppard, Ian D. Krantz Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Coleman M. Serotonin concentrations in whole blood of hyperactive children. J Pediatr 1971;78:985-90. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Jessica M. Jary, Terrill Bravender Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Chamberlain JL, Perry LW. Infantile periarteritis nodosa with coronary and brachial aneurysms: a case diagnosed during life. J  Pediatr 1971;78:1039-42. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Samuel S. Gidding Tags: Original Article Source Type: research

50 Years Ago in The Journal of Pediatrics
Fiser RH, Maetz HM, Treuting JJ, Decker WJ. Activated charcoal in barbiturate and glutethimide poisoning of the dog. J Pediatr 1971;78:1045-7. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Bryan Combs, Philip Toltzis Tags: Original Article Source Type: research

Race impacts concussion
Over the past decade The Journal of Pediatrics and other journals have published an abundance of studies on youth concussion, often with a focus on sports-related concussion. Pediatricians have thus become increasingly familiar with the diagnosis and management of concussion, and our children have no doubt benefitted from attention to what was a previous neglected injury. But, how well do we understand the mechanism of injury? Do all children suffer the same mechanism for concussion? (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Paul G. Fisher Tags: The Editors' Perspectives Source Type: research

Making the grade with quality reports
The current volume of The Journal includes a study from Fogel et al at Penn State, which reports on the results of a quality improvement study at their institution. These workers aimed to improve adherence with current guidelines on lead screening in children in some of their affiliated practices. The study found that an educational intervention produced very little change in practitioner behavior, as assessed by medical record documentation of appropriate lead testing. However, introduction of a point of care (POC) testing device in one of the clinics resulted in striking and durable improvement in screening. (Source: The...
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Thomas R. Welch Tags: The Editors' Perspectives Source Type: research

Autism screening: The perfect vs the good
There is no question that we, with our current screening tools are imperfect at identifying many children with the heterogeneous Autism Spectrum Disorder (ASD) (Pediatrics 2020;145:e20193447. doi:10.1542/peds.2019-3447). Until we have more accurate and culturally appropriate methods, pediatricians and other providers of care to children must continue to rely on a variety of broadband developmental screening and autism-specific instruments, and do so at any early age when interventions can have the greatest impact. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Jane A. Oski Tags: The Editors' Perspectives Source Type: research

Table of Contents
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Source Type: research

Masthead
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Source Type: research

Information for Readers
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Source Type: research

Care for chronic musculoskeletal pain varies across age
An increasing prevalence of chronic musculoskeletal (MSK) pain conditions has been documented for children, adolescents, and young adults. Despite this increase, there has been scarce literature examining treatment modalities for MSK and, in particular, differences in treatments across ages. In this volume of The Journal, Feldman and Nahin reported treatment trends for children and young adults who had received care for MSK. The results indicated that non-opioid medication use was the most commonly prescribed intervention, relative to other interventions such as counseling and physical therapy, and that the primary mode of...
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Henry S. Roane Tags: The Editors' Perspectives Source Type: research

Changes in Self-reported Quality of Life as Survivors of Extremely Preterm Birth Enter Adulthood
Advances in perinatal care of mothers and newborn infants have led to large increases in survival after extremely preterm birth. Currently, with proactive perinatal care, almost one-third of infants born at 22 weeks of gestation survive.1 Interest continues to grow in long-term outcomes among survivors of extreme prematurity. Extreme prematurity is associated with high rates of perinatal brain injury, chronic lung disease, retinopathy, and systemic infections and contributes disproportionately to the burden of neurodevelopmental impairments, such as cognitive impairment, and accompanying functional impairments. (Source: Th...
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Genevieve Taylor, T Michael O ’Shea Tags: Editorials Source Type: research

Pachydermodactyly
An otherwise healthy 17-year-old male presented with a 5-year history of asymptomatic progressive swelling involving multiple fingers of both hands. There was no history of pruritus. Physical examination revealed nontender fusiform swelling of the soft tissue over the dorsal, medial and lateral aspects of the proximal interphalangeal joints of the fingers (except the thumbs) bilaterally (Figures 1 and 2). The range of motion of the fingers was unaffected. A clinical diagnosis of pachydermodactyly was made. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 21, 2021 Category: Pediatrics Authors: Alexander K.C. Leung, Joseph M. Lam Tags: Rediscovering the Physical Exam Source Type: research

Ethics of Organ Transplantation in Persons with Intellectual Disability
Historically, individuals with intellectual disability and end-stage organ disease were discriminated against by transplant professionals and often excluded from transplantation waitlists. Despite antidiscrimination legislation, some transplant programs continue to include intellectual disability as a relative, if not an absolute, contraindication to listing for an organ; this is true for both pediatric and adult individuals in end-stage organ disease. This commentary opposes the absolute exclusion of patients with intellectual disability and end-stage organ disease from transplantation waitlists provided that the candidat...
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Lainie Friedman Ross Tags: eflections on thics and dvocacy in hild ealth Source Type: research

Implementing Rapid Whole-Genome Sequencing in Critical Care: A Qualitative Study of Facilitators and Barriers to New Technology Adoption
To characterize the views of members of the multi-disciplinary team regarding the implementation of rapid whole-genome sequencing (rWGS) as a first-tier test for critically ill children in diverse children's hospital settings. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Linda S. Franck, Rebecca M. Kriz, Seema Rego, Karen Garman, Charlotte Hobbs, David Dimmock Tags: Original Articles Source Type: research

A New Hour-Specific Serum Bilirubin Nomogram for Neonates ≥35 Weeks of Gestation
To develop a statistically rigorous, hour-specific bilirubin nomogram for newborns based on a very large data set; and use it prospectively as a replacement for the 1999 Bhutani nomogram. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Timothy M. Bahr, Erick Henry, Robert D. Christensen, Stephen D. Minton, Vinod K. Bhutani Tags: Original Articles Source Type: research

Study of Acute Liver Failure in Children Using Next Generation Sequencing Technology
To use next generation sequencing (NGS) technology to identify undiagnosed, monogenic diseases in a cohort of children who suffered from acute liver failure (ALF) without an identifiable etiology. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Robert Hegarty, Philippa Gibson, Melissa Sambrotta, Sandra Strautnieks, Pierre Foskett, Sian Ellard, Julia Baptista, Suzanne Lillis, Sanjay Bansal, Roshni Vara, Anil Dhawan, Tassos Grammatikopoulos, Richard J. Thompson Tags: Original Articles Source Type: research

Randomized Placebo-Controlled Trial of Topical Mupirocin to Reduce Staphylococcus aureus Colonization in Infants in the Neonatal Intensive Care Unit
To evaluate the efficacy of topical mupirocin in reducing Staphylococcus aureus colonization in infants in the neonatal intensive care unit (NICU). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Melissa U. Nelson, Jana Shaw, Steven J. Gross Tags: Original Articles Source Type: research

Implementing Rapid Whole Genome Sequencing in Critical Care: A Qualitative Study of Facilitators and Barriers to New Technology Adoption
To characterize the views of members of the multi-disciplinary team regarding the implementation of Rapid Whole Genome Sequencing (rWGS) as a first-tier test for critically ill children in diverse children ’s hospital settings. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Linda S. Franck, Rebecca M. Kriz, Seema Rego, Karen Garman, Charlotte Hobbs, David Dimmock Tags: Original Articles Source Type: research

The Ethics of Organ Transplantation in Persons with Intellectual Disability by Lainie Friedman Ross, MD, PhD
Historically, individuals with intellectual disability and end-stage organ disease were discriminated against by transplant professionals and often excluded from transplantation waitlists. Despite anti-discrimination legislation some transplant programs continue to include intellectual disability as a relative, if not an absolute, contraindication to listing for an organ; this is true for both pediatric and adult individuals in end-stage organ disease. This commentary opposes the absolute exclusion of patients with ID and end-stage organ disease from transplantation waitlists provided that the candidates are expected to ga...
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Lainie F. Ross Source Type: research

A New Hour-Specific Serum Bilirubin Nomogram for Neonates ≥35 Weeks of Gestation
To develop a statistically rigorous, hour-specific bilirubin nomogram for newborns based on a very large data set; and use it prospectively as a replacement for the 1999 Bhutani nomogram. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Timothy M. Bahr, Erick Henry, Robert D. Christensen, Stephen D. Minton, Vinod K. Bhutani Tags: Original Articles Source Type: research

Eosinophilic Bloody Stool in a Neonate
A 5-day-old boy with a birth weight of 2,276 g, born to a gravida 1 para 2 mother at 37 weeks of gestation, was transferred to our hospital because of bloody stools and vomiting. He had bloody stools after taking a formula made from cow's milk since 2 days of age He had no fever and had normal vital signs and sucking ability, but he did not gain weight. On admission, blood tests showed peripheral blood eosinophilia (1,224 cells/mm3), mild elevation of C-reactive protein level (3.2 mg/L), without anemia, hypoglycemia, and electrolyte derangements. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: Manabu Miyamoto, Masaya Kato, Hiroshi Suzumura, Shigemi Yoshihara Tags: Insights and Images Source Type: research

Outcomes of Very Preterm Infants Conceived with Assisted Reproductive Technologies
To compare mortality and early respiratory outcomes of very preterm infants conceived via assisted reproductive technology (ART) versus spontaneously. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 20, 2021 Category: Pediatrics Authors: David C. Fineman, Roberta L. Keller, Emin Maltepe, Paolo F. Rinaudo, Martina A. Steurer Tags: Original Articles Source Type: research

Stevens-Johnson Syndrome in Children: Consider Monitoring for Bronchiolitis Obliterans
We reviewed patients with Stevens-Johnson syndrome (SJS) evaluated at Children's Hospital Colorado and investigated the occurrence of bronchiolitis obliterans (BO). Approximately 9% of patients with SJS developed BO. Pediatricians should consider monitoring patients with SJS for BO, especially those with recurrent SJS and patients treated with mechanical ventilation. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2021 Category: Pediatrics Authors: Lauren M. Carpenter, Jason P. Weinman, Yeva Aleksanyan, Alix K. Mizoue, Robin R. Deterding, Deborah R. Liptzin Tags: Brief Reports Source Type: research

Late Diagnosis of Congenital Toxoplasmosis With Macrocephaly in Dizygotic Twins After Incidental Detection of Leukocoria: A Case Report
We describe a pair of twins diagnosed with congenital toxoplasmosis at 11 months of age following incidental detection of leukocoria in one twin. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2021 Category: Pediatrics Authors: Coralee Del Valle Mojica, Jose G. Montoya, Jennifer McGuire, Krisha L. Palma, Karuna V. Shekdar, Rima McLeod, Despina G. Contopoulos-Ioannidis Tags: Brief Reports Source Type: research

Normative Echocardiographic Values for Right and Left Ventricular Function in Extremely Premature Neonates
To identify the measures of biventricular function and surrogates of pulmonary vascular resistance that can be expected in relatively stable extremely premature neonates, and evaluate maturational changes in myocardial performance in this patient population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2021 Category: Pediatrics Authors: Amir H. Ashrafi, Wyman Lai, Sharib Gaffar, Pierangelo Renella Tags: Original Articles Source Type: research

Chronic Hepatitis Is Common and Often Untreated Among Children With Hepatitis B Infection in the United States and Canada
To determine the outcomes of chronic hepatitis B virus (HBV) infection in a large, prospectively studied cohort of children in the USA and Canada. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2021 Category: Pediatrics Authors: Simon C. Ling, Hsing-Hua S. Lin, Karen F. Murray, Philip Rosenthal, Douglas Mogul, Norberto Rodriguez-Baez, Sarah Jane Schwarzenberg, Jeffrey Teckman, Kathleen B. Schwarz, Hepatitis B Research Network (HBRN) Tags: Original Articles Source Type: research

Stevens Johnson Syndrome in Children: Consider Monitoring for Bronchiolitis Obliterans
We reviewed patients with Stevens Johnson Syndrome (SJS) evaluated at Children ’s Hospital Colorado and investigated the occurrence of bronchiolitis obliterans (BO). Approximately 9% of patients with SJS developed BO. Pediatricians should consider monitoring patients with SJS for BO, especially those with recurrent SJS and patients treated with mechanical ventilation. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 19, 2021 Category: Pediatrics Authors: Lauren M. Carpenter, Jason P. Weinman, Yeva Aleksanyan, Alix K. Mizoue, Robin R. Deterding, Deborah R. Liptzin Tags: Brief Reports Source Type: research

Correlation of Coronary Artery Abnormalities with Fever Pattern in Patients with Kawasaki Disease
To investigate the incidence of coronary artery abnormalities (CAAs) by fever pattern after intravenous immunoglobulin (IVIG) therapy in patients with Kawasaki disease. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2021 Category: Pediatrics Authors: Atsushi Tanaka, Masataka Inoue, Takayuki Hoshina, Hiroshi Koga Tags: Original Articles Source Type: research

Multicenter validation of the neonatal sequential organ failure assessment score for prognosis in the neonatal intensive care unit
Infants in the neonatal intensive care unit are at risk of life-threatening organ dysfunction, but few objective tools with utility exist. In a multicenter cohort of 20,152 infants, we show the neonatal sequential organ failure assessment (nSOFA) score had good-to-excellent discrimination of mortality across centers, birthweights, and timepoints after admission. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2021 Category: Pediatrics Authors: James L. Wynn, Anoop Mayampurath, Kyle Carey, Susan Slattery, Bree Andrews, L. Nelson Sanchez-Pinto Tags: Brief Reports Source Type: research

What Will it Take to Achieve Routine Screening for Abuse?
The field of child abuse pediatrics has moved largely toward standardized approaches and away from the emphasis on a clinician ’s expert gestalt. To decrease missed abuse, and to guard against intrinsic bias, one is now more likely to see a recommendation to obtain skeletal survey in all infants with torso, ear, or neck bruising, for example, than the classic admonition to consider abuse in a family with poor eye contact. 1-4 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2021 Category: Pediatrics Authors: Daniel M. Lindberg Tags: Editorials Source Type: research

The Correlation of Coronary Artery Abnormalities With Fever Pattern in Patients With Kawasaki Disease
To investigate the incidence of coronary artery abnormalities (CAAs) by fever pattern after intravenous immunoglobulin (IVIG) therapy in patients with Kawasaki disease. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2021 Category: Pediatrics Authors: Atsushi Tanaka, Masataka Inoue, Takayuki Hoshina, Hiroshi Koga Tags: Original Articles Source Type: research

Physiology of Low Blood Pressure During the First Day After Birth Among Extremely Preterm Neonates
To investigate the circulatory physiology of hypotension during the first day after birth among stable extremely preterm neonates. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 18, 2021 Category: Pediatrics Authors: Jose Carlos Aldana-Aguirre, Poorva Deshpande, Amish Jain, Dany E. Weisz Tags: Original Articles Source Type: research