Protecting Vulnerable Infants by Ensuring Safe Infant Formula Use
Although it is unquestionable that breastfeeding by an infant's mother is the best route to provide nutrition for infants, it is recognized that this is not always feasible or chosen for a variety of reasons. The debate regarding the role of human milk substitutes, their marketing, and the challenges of supporting breastfeeding have dominated recent discussions about infant formula use. Lost in much of this often-contentious discussion has been a consideration of how best to ensure that infants who are receiving infant formula receive a safe product and that it is provided in a manner that optimizes neonatal outcomes. (Sou...
Source: The Journal of Pediatrics - May 9, 2019 Category: Pediatrics Authors: Steven A. Abrams, Stephen R. Daniels Tags: Commentary Source Type: research

Strategies to Improve Physical Activity Surveillance among Youth in the United States
Physical activity has well documented benefits for youth, including improved academic achievement, musculoskeletal health, cardiovascular health, adiposity, blood pressure, and mental health.1-4 However, adherence to physical activity guidelines is low. Only a small portion of American children achieve the recommended 1  hour or more of moderate-to-vigorous physical activity daily.5 National, state, and local programs and policies to promote physical activity in children rely on regular and comprehensive surveillance of physical activity behaviors in youth to assess critical areas of need and evaluate impact of pr ogr...
Source: The Journal of Pediatrics - May 8, 2019 Category: Pediatrics Authors: Genevieve F. Dunton, David Berrigan, Deborah Rohm Young, Karin Allor Pfeiffer, Sarah M. Lee, Sandy J. Slater, Russell R. Pate Tags: Workshop/Symposium Summary Source Type: research

Association of Circulating Proinflammatory and Anti-inflammatory Protein Biomarkers in Extremely Preterm Born Children with Subsequent Brain Magnetic Resonance Imaging Volumes and Cognitive Function at Age 10 Years
To examine elevated neonatal inflammatory and neurotrophic proteins from children born extremely preterm in relation to later childhood brain Magnetic Resonance Imaging volumes and cognition. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 7, 2019 Category: Pediatrics Authors: Karl C.K. Kuban, Hernan Jara, T. Michael O'Shea, Timothy Heeren, Robert M. Joseph, Raina N. Fichorova, Khalid Alshamrani, Adam Aakil, Forrest Beaulieu, Mitchell Horn, Laurie M. Douglass, Jean A. Frazier, Deborah Hirtz, Julie Vanier Rollins, David Cochran, Tags: Original Articles Source Type: research

Thyroid Function in Monozygotic Twins with Intra-twin Birth Weight Differences: A Prospective Longitudinal Cohort Study
To analyze the long-term impact of birth weight (BW) on thyroid function in genetically identical twins with intra-twin BW differences from birth to adolescence. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 7, 2019 Category: Pediatrics Authors: Sandra Schulte, Bettina Gohlke, Felix Schreiner, Mathias Gruenewald, Rolf Fimmers, Birgit Stoffel-Wagner, Peter Bartmann, Joachim Woelfle Tags: Original Articles Source Type: research

Airway Histopathology of Adolescent Survivors of Bronchopulmonary  Dysplasia
Long-term survivors of bronchopulmonary dysplasia develop chronic obstructive lung disease. Herein we report in  vivo histopathology from bronchial biopsies of 3 adolescent survivors of severe bronchopulmonary dysplasia. Thickened basement membranes with lymphocytic infiltrates and signs of immature neoangiogenesis in the absence of T-helper lymphocytes or eosinophils suggest the presence of an ongoing activ e airway process. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 7, 2019 Category: Pediatrics Authors: Alfonso Galderisi, Fiorella Calabrese, Francesco Fortarezza, Steve Abman, Eugenio Baraldi Tags: Brief Reports Source Type: research

Predictors of the Performance of Early Antireflux Surgery in Esophageal Atresia
To identify predictors of and factors associated with the performance of antireflux surgery during the first year of life in children born with esophageal atresia. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 6, 2019 Category: Pediatrics Authors: Berengere Fran çois, Laurent Michaud, Rony Sfeir, Arnaud Bonnard, Veronique Rousseau, Sebastien Blanc, Thomas Gelas, Julia Boubnova, Catherine Jacquier, Sabine Irtan, Anne Breton, Virginie Fouquet, Audrey Guinot, Thierry Lamireau, Edouard Habounimana, An Tags: Original Articles Source Type: research

Consumption of Mother's Own Milk by Infants Born Extremely Preterm Following Implementation of a Donor Human Milk Program: A Retrospective Cohort Study
To compare mothers' own milk (MOM) consumption by infants born extremely preterm before and after implementation of a donor human milk (DHM) program and determine healthcare provider's knowledge and practices regarding DHM. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 3, 2019 Category: Pediatrics Authors: Leslie A. Parker, Nicole Cacho, Clara Engelmann, Jaime Benedict, Susan Wymer, Weaver Michael, Josef Neu Tags: Original Articles Source Type: research

Childhood Metabolic Biomarkers Are Associated with Performance on Cognitive Tasks in Young Children
To evaluate the hypothesis that metabolic measures (fasting glucose, insulin, and Homeostatic Model of Assessment for Insulin Resistance [HOMA-IR] levels) are inversely associated with performance on cognitive tasks using data from young (4- to 6-year-old), typically developing, healthy children. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 3, 2019 Category: Pediatrics Authors: Allison L.B. Shapiro, Greta Wilkening, Jenny Aalborg, Brandy M. Ringham, Deborah H. Glueck, Jason R. Tregellas, Dana Dabelea Tags: Original Articles Source Type: research

Nicolau Syndrome: A Rare Complication following Intramuscular Injection
A 5-year-old boy presented to the emergency department with a 2-day history of fever, sore throat, abdominal pain, and vomiting. He was prescribed amoxicillin for suspected streptococcal pharyngitis, however, this was not tolerated due to severe vomiting. He was given an intramuscular (IM) injection of benzathine penicillin G in the right deltoid and subsequently developed arm pain and erythema (Figure  1). Due to worsening gangrenous changes and concern for compartment syndrome with loss of peripheral pulses, the patient underwent fasciotomy (Figure 2; available at www.jpeds.com). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 3, 2019 Category: Pediatrics Authors: Elizabeth Quincer, Preeti Jaggi Tags: Rediscovering the Physical Exam Source Type: research

Asymmetric Crying Facies Syndrome
A female infant, born vaginally at 40  weeks of gestation with a birthweight of 3260 g had an Apgar score of 10 at 1 and 5 minutes. She presented with an asymmetric facial expression when crying, with the right side of her mouth deviating inferior-laterally (Figure, A and Video [available at www.jpeds.com]). At rest, her facial expre ssion was symmetric and a thinner left lower lip was noted (Figure, B). A pediatric neurologist noted intact motor, reflex, and cranial nerve functions, and she was diagnosed with asymmetric crying facies, likely because of hypoplasia of the left depressor angularis oris muscle....
Source: The Journal of Pediatrics - May 3, 2019 Category: Pediatrics Authors: Kai-Yu Ho, Jing Nong Liang Tags: Rediscovering the Physical Exam Source Type: research

Test Accuracy of the Screening Tool for Early Predictors of Post-traumatic Stress Disorder for Post-injury Mental Health in a Managed-Medicaid Population
To determine the Screening Tool for Early Predictors of Post-Traumatic Stress Disorder (STEPP) test accuracy in identifying children with new mental health diagnoses and psychotropic medications prescribed within 12  months after unintentional injuries in a managed-Medicaid population. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 2, 2019 Category: Pediatrics Authors: Lindsay Buchanan, Kylie Bushroe, Lauren Malthaner, Tara McCarthy, Songzhu Zhao, Erinn Hade, Julie C. Leonard Tags: Original Articles Source Type: research

Promoting Parenting Supports and Engagement for Infants Born Preterm
There has been increasing recognition that there is a spectrum of developmental, communicative, coordination, regulatory, social −emotional, and adaptive behavior outcomes among survivors of prematurity.1-4 However, resources for supportive interventions have not been systematically available to families. Both neonatal developmental follow-up programs for those at greatest risk of disability and early-intervention programs for these vulnerable children have limited capacity to comprehensively address health, development, and behavior in the context of child functioning, parental well-being, and accessible community s...
Source: The Journal of Pediatrics - May 2, 2019 Category: Pediatrics Authors: Michael E. Msall Tags: Editorials Source Type: research

The Autism Managing Eating Aversions and Limited Variety Plan vs Parent  Education: A Randomized Clinical Trial
To assess the feasibility and initial efficacy of a structured parent training program for children with autism spectrum disorder and moderate food selectivity. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 2, 2019 Category: Pediatrics Authors: William G. Sharp, T. Lindsey Burrell, Rashelle C. Berry, Kathryn H. Stubbs, Courtney E. McCracken, Scott E. Gillespie, Lawrence Scahill Tags: Original Articles Source Type: research

Sex- and Age-specific Increases in Suicide Attempts by Self-Poisoning in the United States among Youth and Young Adults from 2000 to 2018
To evaluate the incidence and outcomes from intentional suspected-suicide self-poisoning in children and young adults ages 10-24  years old from 2000 to 2018. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 1, 2019 Category: Pediatrics Authors: Henry A. Spiller, John P. Ackerman, Natalie E. Spiller, Marcel J. Casavant Tags: Original Article Source Type: research

Impact of Early Exposure to Cefuroxime on the Composition of the Gut Microbiota in Infants Following Cesarean Delivery
To assess in mothers giving birth by cesarean delivery if prophylactic antibiotics administered either before skin incision or immediately after cutting the umbilical cord influences gut microbiota colonization and antibiotic susceptibility of the gut bacteria in the newborn. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 30, 2019 Category: Pediatrics Authors: Shamrulazhar S. Kamal, Nana Hyldig, Łukasz Krych, Gorm Greisen, Karen A. Krogfelt, Gitte Zachariassen, Dennis S. Nielsen Tags: Original Articles Source Type: research

Intermediate-Term Efficacy and Tolerance of Statins in Children
To evaluate the intermediate-term efficacy and tolerance of statins in children and adolescents with familial hypercholesterolemia. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 30, 2019 Category: Pediatrics Authors: Nathalie Mamann, Julie Lemale, Alexandra Karsenty, B éatrice Dubern, Jean-Philippe Girardet, Patrick Tounian Tags: Original Articles Source Type: research

Neonatal Marfan Syndrome: A Rare, Severe, and Life-Threatening Genetic Disease
A 36  weeks of gestational age newborn was admitted to the neonatal intensive care unit because of fetal diagnosis of dilated myocardiopathy. At admission, phenotypic features were noticed; specifically, she had a dolichocephalic skull shape, “senile” facial appearance, narrow forehead with low hair implantation, low ear implantation, blepharophimosis, retrognathia, and ogival palate. In addition, arachnodactyly was noted on hands and feet and multiple joint contractures in flexion (Figure 1), narrow thorax, and umbilical hernia. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 30, 2019 Category: Pediatrics Authors: Anna Sol é-Ribalta, Xavier Rodríguez-Fanjul, Juna Manuel Carretero-Bellon, Carla Pascual-Sala, Loreto Martorell-Sampol, Sara Bobillo-Pérez, Ana María Morillo-Palomo Tags: Rediscovering the Physical Exam Source Type: research

Virtual Reality for Pediatric Needle Procedural Pain: Two Randomized Clinical Trials
To assess the efficacy and safety of a virtual reality distraction for needle pain in 2 common hospital settings: the emergency department (ED) and outpatient pathology (ie, outpatient laboratory). The control was standard of care (SOC) practice. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 29, 2019 Category: Pediatrics Authors: Evelyn Chan, Michael Hovenden, Emma Ramage, Norman Ling, Jeanette H. Pham, Ayesha Rahim, Connie Lam, Linly Liu, Samantha Foster, Ryan Sambell, Kasthoori Jeyachanthiran, Catherine Crock, Amanda Stock, Sandy M. Hopper, Simon Cohen, Andrew Davidson, Karin Pl Tags: Original Articles Source Type: research

Is There a Role for pH Impedance Monitoring in Identifying Eosinophilic Esophagitis in Children with Esophageal Atresia?
To evaluate clinical, endoscopic, and pH-impedance measures in a cohort of children with esophageal atresia and concomitant eosinophilic esophagitis (EoE) and compared it with disease-matched controls, to identify predictive factors for the development of EoE and esophageal stricture. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 26, 2019 Category: Pediatrics Authors: Marcella Pesce, Usha Krishnan, Efstratios Saliakellis, Robert Lopez, Keith J. Lindley, Nikhil Thapar, Osvaldo Borrelli Tags: Original Articles Source Type: research

Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic Shock: A Retrospective Cohort Study
To investigate the association between body habitus and mortality in critically ill children with sepsis or septic shock. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 26, 2019 Category: Pediatrics Authors: Patrick A. Ross, Margaret J. Klein, Tuan Nguyen, Dennis Leung, Robinder G. Khemani, Christopher J.L. Newth, Anoopindar K. Bhalla Tags: Original Articles Source Type: research

No Effect of Glucomannan on Body Weight Reduction in Children and Adolescents with Overweight and Obesity: A Randomized Controlled Trial
To assess the efficacy of water-soluble dietary fiber, glucomannan supplementation, on the body mass index (BMI) in children with overweight or obesity. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 26, 2019 Category: Pediatrics Authors: Bart łomiej Mateusz Zalewski, Hania Szajewska Tags: Original Articles Source Type: research

Black, White, and Hispanic Children's Health and Function 2-13  Months After Sibling Intensive Care Unit Death
To describe children's anxiety, depression, behaviors, and school performance at 2-13  months after sibling neonatal/pediatric intensive care unit (NICU/PICU) or emergency department (ED) death and compare these outcomes by child age, sex, race/ethnicity, whether the child saw their sibling in the NICU/PICU/ED, and attended the sibling's funeral. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 25, 2019 Category: Pediatrics Authors: JoAnne M. Youngblut, Dorothy Brooten, Teresa Del-Moral, G. Patricia Cantwell, Balagangadhar Totapally, Changwon Yoo Tags: Original Articles Source Type: research

A Mixed Lipid Emulsion Containing Fish Oil and Its Effect on Electrophysiological Brain Maturation in Infants of Extremely Low Birth Weight: A Secondary Analysis of a Randomized Clinical Trial
To assess whether parenteral nutrition for infants of extremely low birth weight using a mixed lipid emulsion that contains fish oil influences electrophysiological brain maturation. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 25, 2019 Category: Pediatrics Authors: Christoph Binder, Vito Giordano, Margarita Thanhaeuser, Alexandra Kreissl, Mercedes Huber-Dangl, Nicholas Longford, Nadja Haiden, Angelika Berger, Andreas Repa, Katrin Klebermass-Schrehof Tags: Original Articles Source Type: research

Gaze Palsy: An Important Diagnostic Clue
A 30-month-old boy presented with global developmental delay and generalized dystonia since infancy. He was born to nonconsanguineous parents at term. He had a history of bilirubin encephalopathy requiring exchange blood transfusion on day 2 of life; maximum documented serum bilirubin was 20  mg/dL. On examination, he was hypotonic with intermittent dystonia involving all 4 limbs. He had a specific gaze restriction (Video; available at www.jpeds.com) that clinched the clinical diagnosis. Neuroimaging revealed bilateral globus pallidus hyperintensities (Figure). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 24, 2019 Category: Pediatrics Authors: Priyanka Madaan, Chaitanya Reddy, Lokesh Saini Tags: Rediscovering the Physical Exam Source Type: research

50 Years Ago in The Journal of Pediatrics
Winick M. J Pediatr 1969;74:667-79 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Jacqueline M. Lauer, Christopher P. Duggan Source Type: research

50 Years Ago in The Journal of Pediatrics
Yow MD. J Pediatr 1969;74:848-52. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Carol J. Baker, Sarah S. Long Source Type: research

50 Years Ago in The Journal of Pediatrics
Dehner LP, Kissane JM. J Pediatr 1969;74:763-73 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Sarah S. Long Source Type: research

50 Years Ago in The Journal of Pediatrics
Blattner RJ. J Pediatr 1969;74:835-7 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Erin E. Neil Source Type: research

50 Years Ago in The Journal of Pediatrics
Seeds AE, Behrman RE. J Pediatr 1969;74:804-7 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Jannicke H. Andresen, Ola Didrik Saugstad Tags: 50 Years Ago Source Type: research

50 Years Ago in The Journal of Pediatrics
Cash R, Berger CK. J Pediatr 1969;74(5):717-29 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Bhavna Dhingra, Piyush Gupta Source Type: research

50 Years Ago in The Journal of Pediatrics
Tasker W, Chutorian AM. J Pediatr 1969;74:699-708 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Jenna Klotz, Carolina Tesi Rocha Source Type: research

50 Years Ago in The Journal of Pediatrics
Coleman SJ, Auld EB, Connor JD, Rosenman SB, Warren GH. J Pediatr 1969;74:781-4 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Philip Toltzis Source Type: research

Corrigendum
In the article “Normative Cerebrospinal Fluid Profiles in Febrile Infants” by Byington et al (J Pediatr 2011;158:130-4), one of the tables had an incorrect table. The title of Table I should read “Cerebrospinal fluid white blood cell counts in uninfected febrile infants 1 to 90 days old with atraumatic lum bar punctures.” (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Tags: Corrections Source Type: research

Corrigendum
In this article “Food Insecurity and Family Well-Being Outcomes among Households with Young Children”, by Johnson& Markowitz, (J Pediatr 2017;196:275-282) two errors were present in equation 2. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Tags: Corrections Source Type: research

Corrigendum
In the article “Statewide Initiative to Reduce Postnatal Growth Restriction Among Infants (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Tags: Corrections Source Type: research

Prevention and Therapeutic Innovation in the Management of Child Health
The topics of prevention and therapeutic innovation in the management of infant, child, and adolescent health have progressively acquired global importance for their direct effects on the lifelong health and well-being of populations. If appropriately implemented, they have the potential to positively impact various areas of the public health sector,1 generating beneficial outcomes, which include major economic implications for local healthcare systems. Responding to the emerging preventive and health promotion needs of infants, children, and adolesents has become a priority for pediatrics, and together with therapeutic in...
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Hilary Hoey, Terence Stephenson, Leyla Namazova-Baranova, Massimo Pettoello-Mantovani, Julije Mestrovic, Mehmet Vural, Ellen Crushell Tags: European Paediatric Association Source Type: research

Should Pediatric Chairs Be Expected to Write Letters of Recommendation for All Students Applying to Pediatric Residency Programs?
Letters of recommendation are an important component of fourth year medical students' applications to  residency programs. Aspiring pediatric residents commonly request letters of recommendation from the chair of their medical school's pediatric department. This request is made because of either a real or perceived notion that having a letter from the chair is required or highly recommended. Member s of the Association of Medical School Pediatric Department Chairs (AMSPDC) have raised the issue of whether it is appropriate for writing such a letter to be deemed compulsory by the dean of their medical school or by resi...
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Alice D. Ackerman, Lewis R. First Tags: Notes from the Association of Medical School Pediatric Department Chairs, Inc. Source Type: research

Corrigendum
In the Editor ’s Perspective “Have Zackery Lystedt concussion laws made an impact?” by Fisher (J Pediatr 2019;206:2-3), it was erroneously reported that Zackery Lystedt died from an intracranial hemorrhage. Although Zackery Lystedt did experience a severe brain injury playing football, he survived, and has continued to advocate for concussion management awareness. We apologize for this error. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Tags: Corrections Source Type: research

Neonatal Intensive Care Unit Medical Directors in Academic Institutions: Who Are They?
Newborn care has evolved rapidly through innovation, an ever-expanding body of scientific literature, and the development of multidisciplinary care teams dedicated solely to treating the fetus and newborn in highly advanced delivery rooms and intensive care units. In parallel with these medical advances, neonatal intensive care units (NICUs) have increasingly relied on complex systems to support clinical care, which requires significant oversight and management, usually by a physician medical director. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: James S. Barry, Michael D. Baca, Thomas F. Parker Tags: Notes from the Association of Medical School Pediatric Department Chairs, Inc. Source Type: research

AAP recommends isotonic maintenance intravenous fluid
Feld LG, Neuspiel DR, Foster BA, Leu MG, Garber MD, Austin K, et al. Clinical Practice Guideline: Maintenance Intravenous Fluids in Children. Pediatrics 2018;142.pii: e20183083. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Jeffery L. Segar Tags: Current Best Evidence Source Type: research

AR101 prevents peanut allergy reactions in highly peanut-allergic children
Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, et al. AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med 2018;379:1991-2001. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Pablo Rodr íguez del Río Tags: Current Best Evidence Source Type: research

Afebrile infants presenting to the emergency department with only a history of fever have a significant risk of serious bacterial infection
Ramgopal S, Janofsky S, Zuckerbraun NS, Ramilo O, Mahajan P, Kuppermann N, et al. Risk of Serious Bacterial Infection in Infants Aged ≤60 Days Presenting to Emergency Departments with a History of Fever Only. J Pediatr 2019;204:191-5. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Santiago Mintegi Tags: Current Best Evidence Source Type: research

Primary-care-based child maltreatment interventions have not demonstrated efficacy
Viswanathan M, Fraser JG, Pan H, Morgenlander M, McKeeman JL, Forman-Hoffman VL, et al. Primary Care Interventions to Prevent Child Maltreatment: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA 2018;320:2129-40. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Kavita Vankineni Tags: Current Best Evidence Source Type: research

Lactobacillus administration does not affect acute gastroenteritis
Schnadower D, Tarr PI, Casper TC, Gorelick MH, Dean JM, O'Connell KJ, et al. Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children. N Engl J Med 2018;379:2002-14. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Alfredo Guarino Tags: Current Best Evidence Source Type: research

School screening for cardiovascular risk
Universal screening for cardiovascular risk factors in children could improve the early diagnosis of hypertension, dyslipidemia, and diabetes. The current childhood obesity epidemic underscores the relevance of screening for these comorbidities. Siegel et al report the findings of an initial feasibility pilot study of a small group of children aged 12-14 performed in a middle-school setting. The authors showed that screening for hypertension, dyslipidemia, and diabetes was feasible in this setting. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Julia Steinberger Tags: The Editors' Perspectives Source Type: research

Waiting for ELVIS
In this study, infants with post-hemorrhagic ventricular dilation were randomized to a low vs high threshold for intervention, beginning in 2006 and completing in 2016. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Raye-Ann deRegnier Tags: The Editors' Perspectives Source Type: research

Cerebral NIRS —How low is low?
Cerebral near-infrared spectroscopy (NIRS), a noninvasive means of monitoring cerebral oxygenation, is inferred to reflect the balance between tissue oxygen delivery and consumption. Although some studies have demonstrated an association between cerebral NIRS and intellectual outcome in special populations, such as those with hypoplastic left heart syndrome (J Thorac Cardiovasc Surg 2016;151:1358-66), questions remain regarding broader applicability. Although frequently used during anesthesia for congenital heart surgery, use in a broader surgical population is not established, including in adult patients (Anesth Analg 201...
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Denise M. Goodman Tags: The Editors' Perspectives Source Type: research

Preeclampsia and cardiovascular risk in offspring
There is emerging evidence suggesting that offspring of preeclamptic pregnancies may be at increased risk of cardiovascular disease (CVD) in adult life. In this volume of The Journal, Andraweera et al present the results of a meta-analysis of 36 studies with cumulative data in over 53 000 individuals regarding the effect of maternal preeclampsia on CVD risk factors in the offspring. Systolic and diastolic blood pressure were 4-5mmHg higher and body mass index (BMI) was 0.36 kg/m2 higher in preeclamptic offspring compared with controls. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Authors: Julia Steinberger Tags: The Editors' Perspectives Source Type: research

Table of Contents
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Source Type: research

Masthead
(Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 23, 2019 Category: Pediatrics Source Type: research