Tele-Clinic Visits in Pediatric Patients with Marfan Syndrome Using Parentally Acquired Echocardiography
To test feasibility of tele-clinic visits using parentally acquired vital signs and focused echocardiographic images in patients with Marfan syndrome. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 12, 2021 Category: Pediatrics Authors: Angela Chen, Rajesh Punn, R. Thomas Collins, Jonathan H. Chen, Katie Jo Stauffer, Rena Wang, Samantha Alexander, Kirstie MacMillen Lechich, Daniel Jerome Murphy, Sukyung Chung, Elif Seda Selamet Tierney Tags: Original Articles Source Type: research

Tele-Clinic Visits in Pediatric Patients with Marfan Syndrome using Parentally-Acquired Echo
To test feasibility of tele-clinic visits using parentally-acquired vital signs and focused echocardiographic (echo) images in patients with Marfan syndrome. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 12, 2021 Category: Pediatrics Authors: Angela Chen, Rajesh Punn, R. Thomas Collins, Jonathan H. Chen, Katie Jo Stauffer, Rena Wang, Samantha Alexander, Kirstie MacMillen Lechich, Daniel Jerome Murphy, Sukyung Chung, Elif Seda Selamet Tierney Tags: Original Articles Source Type: research

Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Post-natal Indomethacin
To determine if antenatal variables affect the risk of spontaneous intestinal perforation (SIP) among preterm infants when prophylactic indomethacin is used. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 12, 2021 Category: Pediatrics Authors: Tamara I. Arnautovic, Jami L. Longo, Elizabeth J. Trail-Burns, Richard Tucker, Martin Keszler, Abbot R. Laptook Tags: Original Articles Source Type: research

Mortality, Risk Factors and Disparities Associated with Esophageal Variceal Bleeding in Children ’s Hospitals in the United States
To use a large administrative database to determine the mortality, risk factors, and co-morbidities of esophageal variceal bleeding in children. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 12, 2021 Category: Pediatrics Authors: Jean P. Molleston, William E. Bennett Tags: Original Articles Source Type: research

Reply
We want to address their disagreement with our determination to allow only children>10  years old to self-report. In their arguments, the authors ignore that our methods followed the Rome IV Committee guidelines for the use of the official questionnaire for the diagnosis of functional gastrointestinal disorders (Questionnaire on Pediatric Functional Gastrointestinal Disorders, QPGS-I V).1 This document recommended using the self-report questionnaire in children>10  years of age (as opposed to parental report for children (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 11, 2021 Category: Pediatrics Authors: Amanda C. Fifi, Carlos Velasco-Benitez, Miguel Saps Tags: Letters to the Editor Source Type: research

General Cognitive Abilities and Psychosocial Development in Children and Adolescents Having a Co-Twin with Down Syndrome
To examine the general cognitive and psychosocial development in children and adolescents having a co-twin with Down syndrome. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 11, 2021 Category: Pediatrics Authors: Gisa Aschersleben, Katarzyna Hoffmann, Wolfram Henn Tags: Original Articles Source Type: research

Isolated forehead swelling
A previously healthy 3-year-old girl presented to the dermatology department with a 3 week history of swelling of the right forehead. The lesion was a non-painful, non-fluctuant, non-pulsating, indurated mass of about 3x3 cm, increased in size over the past two weeks, and with overlying skin eventually turned purple (Figure 1, A). Ultrasound examination revealed a solid hyperechoic subcutaneous lesion with enhanced doppler signal, intact underlying osseous plate, and ipsilateral submandibular and cervical lymphadenopathy. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 11, 2021 Category: Pediatrics Authors: Daniela Nistico ’, Luisa Cortellazzo Wiel, Irene Berti, Lorenzo Calligaris, Marco Rabusin, Alessia Saccari, Egidio Barbi, Valentina Kiren Tags: Rediscovering the Physical Exam Source Type: research

Response to the Letter to the Editor on Celiac Disease in Children with Functional Constipation. A School Based Multicity Study.
We would like to address their disagreement with our determination to allow only children>10 years old to self-report. In their arguments, the authors ignore that our methods followed the Rome IV Committee guidelines for the use of the official questionnaire for the diagnosis of functional gastrointestinal disorders (Questionnaire on Pediatric Functional Gastrointestinal Disorders, QPGS-IV). (2) This document recommended using the self-report questionnaire in children>10 years of age (as opposed to parental report for children (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 11, 2021 Category: Pediatrics Authors: Amanda C. Fifi, Carlos Velasco-Benitez, Miguel Saps Tags: Letters to the Editor Source Type: research

Considerations for future research on celiac disease in children with functional constipation
Recognition of the symptomatology associated with celiac disease will allow for earlier diagnosis and ultimately better patient outcomes. We read the report by Fifi et  al and appreciate the efforts they have made to attempt to improve the early diagnosis of celiac disease.1 (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 9, 2021 Category: Pediatrics Authors: Samar Al-Shamaa, Alexander Tan Tags: Letters to the Editor Source Type: research

Toward a Rational Approach to Patent Ductus Arteriosus Trials: Selecting the Population of Interest
We read with interest the randomized trial report published by Roze et  al (the Targeted by echocardiographic tReatment Of the duCtus Arteriosus in Preterm Infants by Ibuprofen or TRIOCAPI Trial).1 This investigative group should be applauded for conducting a multi-institutional randomized trial with over 100 patients in each of the 3 groups. We would also like to exp ress our most sincere condolences to the investigative team regarding the untimely death of the principal investigator, Veronique Gournay, whose pioneering vision for this study in addition to her innovative patent ductus arteriosus (PDA) research should...
Source: The Journal of Pediatrics - January 9, 2021 Category: Pediatrics Authors: Afif El-Khuffash, Danielle R. Rios, Patrick J. McNamara Tags: Editorial Source Type: research

Considerations for future research on celiac disease in children with functional constipation Key Words: self-report; diagnosis
Recognition of the symptomatology associated with celiac disease will allow for earlier diagnosis and ultimately better patient outcomes. We read the report by Fifi et al and appreciate the efforts they have made to attempt to improve the early diagnosis of celiac disease (1). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 9, 2021 Category: Pediatrics Authors: Samar Al-Shamaa, Alexander Tan Tags: Letters to the Editor Source Type: research

Towards a Rational Approach to Patent Ductus Arteriosus Trials: Selecting the Population of Interest
We read with interest the randomized trial report published by Roze et al (TRIOCAPI Trial)1. This investigative group should be applauded for conducting a multi-institutional randomized trial with over 100 patients in each of the three groups. We would also like to express our most sincere condolences to the investigative team regarding the untimely death of the principal investigator, Veronique Gournay, whose pioneering vision for this study in addition to her innovative patent ductus arteriosus (PDA) research should be recognized. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 9, 2021 Category: Pediatrics Authors: Afif EL-Khuffash, Danielle R. Rios, Patrick J. McNamara Tags: Editorials Source Type: research

Magnetic resonance biomarkers in very preterm infants: relationships to perinatal factors
T.O ’Shea is supported by the Office of the Director of the National Institutes of Health (5UH3OD023348-05) and the National Institute of Child Health and Human Development (5R01HD092374-04). D.T. is supported by Australian National Health and Medical Research Council (NHMRC) (Centre for Research Exce llence #1153176; Career Development Fellowship #1160003). L.D. is supported by the National Health and Medical Research Council of Australia (Centre of Research Excellence #1153176). The authors declare no conflicts of interest. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 6, 2021 Category: Pediatrics Authors: T. Michael O ’Shea, Deanne K. Thompson, Lex W. Doyle Tags: Editorials Source Type: research

Using Clinical History Factors to Identify Bacterial Infections in Young Febrile Infants
To develop a novel predictive model using primarily clinical history factors and compare performance to the widely-used Rochester Low Risk (RLR) model. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 6, 2021 Category: Pediatrics Authors: Jeffrey P. Yaeger, Jeremiah Jones, Ashkan Ertefaie, Mary T. Caserta, Edwin van Wijngaarden, Kevin Fiscella Tags: Original Articles Source Type: research

Detection of Tachyarrhythmias in a Large Cohort of Infants using Direct-to-Consumer Heart Rate Monitoring
Current estimates of the incidence of tachyarrhythmias in infants rely on clinical documentation and may not reflect the true rate in the general population. Our aim was to describe the epidemiology of tachyarrhythmia detected in a large cohort of infants using direct-to-consumer heart rate monitoring. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 5, 2021 Category: Pediatrics Authors: Scott Anjewierden, Jeffrey Humpherys, Martin J. LaPage, S. Yukiko Asaki, Peter F. Aziz Tags: Original Articles Source Type: research

Predicting Adverse Outcomes for Shiga Toxin –Producing Escherichia coli Infections in Emergency Departments
To assess the performance of a hemolytic uremic syndrome (HUS) severity score among children with Shiga toxin-producing Escherichia coli (STEC) infections and HUS by stratifying them according to their risk of adverse events. The score has not been previously evaluated in a North American acute care setting. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 4, 2021 Category: Pediatrics Authors: Chu Yang Lin, Jianling Xie, Stephen B. Freedman, Ryan S. McKee, David Schnadower, Phillip I. Tarr, Yaron Finkelstein, Neil M. Desai, Roni D. Lane, Kelly R. Bergmann, Ron L. Kaplan, Selena Hariharan, Andrea T. Cruz, Daniel M. Cohen, Andrew Dixon, Sriram Ra Tags: Original Articles Source Type: research

Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature  Infants
To compare in-hospital outcomes after umbilical cord milking vs delayed cord clamping among infants (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 4, 2021 Category: Pediatrics Authors: Neha Kumbhat, Barry Eggleston, Alexis S. Davis, Sara B. DeMauro, Krisa P. Van Meurs, Elizabeth E. Foglia, Satyan Lakshminrusimha, Michele C. Walsh, Kristi L. Watterberg, Myra H. Wyckoff, Abhik Das, Sara C. Handley, Generic Database Subcommittee of the Nat Tags: Original Articles Source Type: research

Umbilical Cord Milking versus Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants
To compare in-hospital outcomes after umbilical cord milking versus delayed cord clamping among infants (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 4, 2021 Category: Pediatrics Authors: Neha Kumbhat, Barry Eggleston, Alexis S. Davis, Sara B. DeMauro, Krisa P. Van Meurs, Elizabeth E. Foglia, Satyan Lakshminrusimha, Michele C. Walsh, Kristi L. Watterberg, Myra H. Wyckoff, Abhik Das, Sara C. Handley, the Generic Database Subcommittee of the Tags: Original Articles Source Type: research

Predicting Adverse Outcomes for Shiga Toxin-Producing E. coli Infections in Emergency Departments
To assess the performance of a hemolytic uremic syndrome (HUS) severity score among children with Shiga toxin-producing Escherichia coli (STEC) infections and HUS by stratifying them according to their risk of adverse events. The score has not been previously evaluated in a North American acute care setting. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 4, 2021 Category: Pediatrics Authors: Chu Yang Lin, Jianling Xie, Stephen B. Freedman, Ryan McKee, David Schnadower, Phillip I. Tarr, Yaron Finkelstein, Neil M. Desai, Roni D. Lane, Kelly R. Bergmann, Ron L. Kaplan, Selena Hariharan, Andrea T. Cruz, Daniel M. Cohen, Andrew Dixon, Sriram Ramgo Tags: Original Articles Source Type: research

Short-term and long-term educational outcomes of infants born moderately and late preterm
To assess the relationship of moderate and late preterm birth (32 –36 6/7 weeks) to long-term educational outcomes. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - January 4, 2021 Category: Pediatrics Authors: Carrie Townley Flores, Amy Gerstein, Ciaran S. Phibbs, Lee M. Sanders Tags: Original Articles Source Type: research

Trends in Pediatric Endoscopic Retrograde Cholangiopancreatography and Interventional Endoscopy
The application of endoscopic retrograde cholangiopancreatography (ERCP) for the pediatric population is expanding, drawing upon the experience of adult ERCP applications during the last 50  years.1-4 In the past, indications for and perceived utility of ERCP in pediatric patients were restrictive. The historical performance of pediatric ERCP procedures had been consigned to adult gastroenterology practitioners because of the paucity of pediatric gastroenterologists with interventio nal endoscopy training. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: David S. Vitale, Tom K. Lin Tags: Editorial Source Type: research

Pulmonary Sarcoidosis: An Unusual Presentation with Acute Abdominal  Pain
An 18-year-old boy with no prior medical history presented to the emergency department with an acute-onset, severe, upper abdominal, nonradiating pain with nausea and constipation. He also complained of excessive fatigue and muscle cramps. His general physical examination was unremarkable. The abdomen was soft, with mild tenderness in the epigastrium. Laboratory results showed elevated serum calcium of 15.5  mg/dL (reference, 8.4-10.2 mg/dL) and elevated serum creatinine of 1.9 mg/dL (reference, 0.8-1.5 mg/dL). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Durga Prasad, Abhai Verma, Rajneesh Kumar Srivastava Tags: Insights and Images Source Type: research

Association of Continuous Opioids and/or Midazolam during Early Mechanical Ventilation with Survival and Sensorimotor Outcomes at Age 2 Years in Premature Infants: Results from the French Prospective National EPIPAGE 2 Cohort
To evaluate the association of early continuous infusions of opioids and/or midazolam with survival and sensorimotor outcomes at age 2 years in ventilated very premature infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Marie-Am élie de Tristan, Laetitia Martin-Marchand, Jean-Michel Roué, Kanwaljeet J.S. Anand, Véronique Pierrat, Pierre Tourneux, Pierre Kuhn, Christophe Milesi, Valérie Benhammou, Pierre-Yves Ancel, Ricardo Carbajal, Xavier Durrmeyer Tags: Original Articles Source Type: research

Neighborhood Conditions and Recurrent Emergency Department Utilization by Children in the United States
To determine the associations of social and physical neighborhood conditions with recurrent emergency department (ED) utilization by children in the United States. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Lawrence Chang, Amanda M. Stewart, Michael C. Monuteaux, Eric W. Fleegler Tags: Original Articles Source Type: research

Quality Improvement and Antenatal Steroids
This excellent epidemiologic data report from the California Perinatal Quality Care Collaborative evaluates the effects of antenatal corticosteroids (ACS) for births from 2005-2016 – 28,252 infants(1). Use of ACS increased from 80.1% to 90.3% with the primary outcomes for in-hospital death and severe intraventricular hemorrhage (IVH) modeled for individual risk factors or with a predicted probability factor for each time interval of analysis. Overall, as use of ANS increased over the time interval, death decreased (12.8% to 9.1%) and severe IVH decreased (11.5% to 8.8%). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Alan H. Jobe Tags: Editorials Source Type: research

Pulmonary Sarcoidosis: An Unusual Presentation with Acute Abdominal Pain
An 18-year-old boy, with no prior medical history presented to the emergency with an acute onset, severe, upper abdominal, non-radiating pain with nausea and constipation. He also complained of excessive fatigue and muscle cramps. His general physical examination was unremarkable. The abdomen was soft with mild tenderness in the epigastrium. Laboratory results showed elevated serum calcium of 15.5 mg/dL (reference, 8.4-10.2 mg/dL) and elevated serum creatinine of 1.9 mg/dL (reference, 0.8-1.5 mg/dL). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Durga Prasad, Abhai Verma, Rajneesh Kumar Srivastava Tags: Insights and Images Source Type: research

“Pressed” Etizolam
Three boys, ages 6, 9, and 10 years old, presented to the emergency department (ED) with altered mental status after eating Pez candy. Their mother had left the boys under an aunt ’s supervision; at approximately 8:30 AM on the day of symptom onset. She returned home at 10:45 AM to find them ”drowsy and wobbly.” The aunt also had altered mental status, and she owned the candy-container. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Jennifer S. Love, John A. Thompson, B. Zane Horowitz Tags: Insights and Images Source Type: research

When measuring is more important than measurement: The importance of measuring diagnostic errors in health care
Diagnostic errors are unacceptably prevalent and harmful, [1,2] yet they have received little attention in the field of patient safety.[3] Reasons for this are the lack of widespread awareness of the problem, the myriad and complex factors leading to diagnostic error, and the lack of clearly defined and generalizable measurement strategies for assessment of the diagnostic process and its outcomes.[4] Furthermore, the diagnostic process reflects one of the core tasks of physicians, making diagnostic errors a sensitive topic to discuss, requiring an open, non-punitive safety culture.[5] (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: Laura Zwaan, Andrew P.J. Olson Tags: Editorials Source Type: research

Trends in pediatric ERCP and interventional endoscopy
The application of endoscopic retrograde cholangiopancreatography (ERCP) for the pediatric population is expanding, drawing upon the experience of adult ERCP applications during the last 50 years.1-4 In the past, indications for and perceived utility of ERCP in pediatric patients were restrictive. The historical performance of pediatric ERCP procedures had been consigned to adult gastroenterology practitioners due to the paucity of pediatric gastroenterologists with interventional endoscopy training. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 31, 2020 Category: Pediatrics Authors: David S. Vitale, Tom K. Lin Tags: Editorials Source Type: research

Comparison of Aerodigestive and Nonaerodigestive Provider Responses to Clinical Case Vignettes
To evaluate differences in practice patterns between aerodigestive and nonaerodigestive providers in pediatric gastroenterology when diagnosing and treating common aerodigestive complaints. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 29, 2020 Category: Pediatrics Authors: Suzanna Hirsch, Joel A. Friedlander, Hayat Mousa, Valeria Cohran, Jose M. Garza, Rinarani Sanghavi, Lusine Ambartsumyan, Paul D. Mitchell, Rachel Rosen, the NASPGHAN Aerodigestive Interest Group Tags: Original Articles Source Type: research

Comparison of Aerodigestive and Non-Aerodigestive Provider Responses to Clinical Case Vignettes
To evaluate differences in practice patterns between aerodigestive and non-aerodigestive providers in pediatric gastroenterology when diagnosing and treating common aerodigestive complaints. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 29, 2020 Category: Pediatrics Authors: Suzanna Hirsch, Joel A. Friedlander, Hayat Mousa, Valeria Cohran, Jose M. Garza, Rinarani Sanghavi, Lusine Ambartsumyan, Paul D. Mitchell, Rachel Rosen, NASPGHAN Aerodigestive Interest Group Tags: Original Articles Source Type: research

The wandering calcified lung nodule
A 1.5-year-old previously healthy fully vaccinated boy presented to the pediatric emergency department with a 3-day history of fever and cough. A history of foreign body aspiration was denied. His parents were refugees from Eritrea. His father had completed therapy for proven tuberculosis 7 years ago. On presentation, the child ’s temperature, saturation, and heart-rate were, 102.6F, 93%, and 170/minute, respectively. He was alert but dyspneic with bilateral wheezing on auscultation. Laboratory tests demonstrated 25,000 u/l leukocytes with elevated C-reactive protein. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 29, 2020 Category: Pediatrics Authors: Michael Schnapper, Avigdor Mandelberg, Michaela Witzling, Racheli Sion Sarid, Ilan Dalal, Keren Armoni Domany Tags: Insights and Images Source Type: research

Treating Cyclic Vomiting Syndrome in the Emergency Department: Sooner Appears Better
Cyclic vomiting syndrome (CVS) is a complex disorder of gut-brain interaction characterized by repeated cyclic or sporadic episodes of extreme nausea, severe vomiting, and retching occurring as often as every 5  minutes. The formation of the Cyclic Vomiting Syndrome Association in 1993 spurred current progress in characterizing the phenotype, uncovering potential mechanistic pathways, and improving acute and preventative management. The North American Society of Pediatric Gastroenterology, Hepatology and Nutrition Consensus Statement in 2008 and the American Neurogastroenterology and Motility Adult Guidelines in 2019 ...
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: B U.K. Li Tags: Editorials Source Type: research

A Cluster Mediation Analysis Confirms the Validity of the “Fat but Fit” Paradigm in Children’s Cognitive Function and Academic Achievement
To evaluate the fat but fit conceptual model, testing whether this paradigm for body mass index (BMI) and maximum rate of oxygen consumption (VO2max) exists in schoolchildren and whether executive functions mediate the relationship between fat but fit categories and academic achievement. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: Vicente Martinez-Vizcaino, Celia Álvarez-Bueno, Mairena Sanchez-Lopez, Estela Jimenez-Lopez, Alba Soriano-Cano, Francisaco B. Ortega, Ivan Cavero-Redondo, Miriam Garrido-Miguel Tags: Original Articles Source Type: research

The Role of Pediatricians in Providing Greater-Quality Care for Children: An  Ongoing Debate
More than 40  years have passed since the first International Conference on Primary Health Care, held in Alma-Ata, Kazakhstan in 1978; 134 countries and 67 international organizations met and established the strategic prominence of primary healthcare, emphasizing its role in maternal and child healthcare.1 Twen ty years later, in 1998, the United Nations Convention on the Rights of the Child was signed by 140 nations and later ratified by a total of 196 nations.2 Although accepted with various reservations or interpretations by the parties, this international treaty is regarded as an event of major histori cal signifi...
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: Maria Aparicio Rodrigo, Angel Carrasco Sanz, Concepci ón Sánchez Pina, Carmen Villaizán Pérez, Mercedes Fernández Rodriguez, Gloria Orejón de Luna, Pilar Aizpurúa Galdeano, Massimo Pettoello-Mantovani Tags: European Paediatric Association Source Type: research

Early Skin-to-skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial
To determine if early polyethylene bag use with skin-to-skin care compared with skin-to skin care alone reduce hypothermia among term infants in resource-limited settings. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: Colm P. Travers, Manimaran Ramani, Samuel J. Gentle, Amelia Schuyler, Catherine Brown, Madeline M. Dills, Claire B. Davis, Musaku Mwenechanya, Elwyn Chomba, Inmaculada Aban, Albert Manasyan, Namasivayam Ambalavanan, Waldemar A. Carlo Tags: Original Articles Source Type: research

The Role of Pediatricians in Providing Higher Quality Care for Children: An Ongoing Debate
Over 40 years have passed since at the first International Conference on Primary Health Care, held in Alma-Ata, Kazakhstan in 1978; 134 countries and 67 international organizations met and established the strategic prominence of primary health care, emphasizing its role in maternal and child health care1. Twenty years later, in 1998 the United Nations Convention on the Rights of the Child was signed by 140 nations and later ratified by a total of 196 nations2. Although accepted with various reservations or interpretations by the parties, this international treaty is regarded as an event of major historical significance for...
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: Aparicio Rodrigo Mar ía, Angel Carrasco Sanz, Concepción Sánchez Pina, Carmen Villaizán Pérez, Mercedes Fernández Fernández, Gloria Orejón de Luna, Pilar Aizpurua Galdeano, Massimo Pettoello-Mantovani Source Type: research

“Treating cyclic vomiting syndrome in the Emergency Department: Sooner appears better”
Cyclic vomiting syndrome (CVS) is a complex disorder of gut-brain interaction characterized by repeated cyclic or sporadic episodes of extreme nausea, severe vomiting and retching occurring as often as every five minutes. Formation of the Cyclic Vomiting Syndrome Association in 1993 spurred current progress in characterizing the phenotype, uncovering potential mechanistic pathways, and improving acute and preventative management. The North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) Consensus Statement in 2008 and the American Neurogastroenterology and Motility Adult Guidelines in 20...
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: B.U.K. Li Tags: Editorials Source Type: research

A cluster mediation analysis confirms the validity of the ‘fat but fit’ paradigm in children’s cognitive function and academic achievement
To evaluate the fat but fit conceptual model, testing whether this paradigm for BMI and VO2max exists in schoolchildren and whether executive functions mediate the relationship between fat but fit categories and academic achievement. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: V. Martinez-Vizcaino, C. Alvarez-Bueno, M. Sanchez-Lopez, E. Jimenez-Lopez, A. Soriano-Cano, F.B. Ortega, I. Cavero-Redondo, M. Garrido-Miguel Tags: Original Articles Source Type: research

Alternative Cerebral Fuels in the First Five Days in Healthy Term Infants: The Glucose in Well Babies (GLOW) Study
To determine plasma lactate and beta-hydroxybutyrate concentrations of healthy infants in the first 5 days and their relationships with glucose concentrations. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 26, 2020 Category: Pediatrics Authors: Deborah L. Harris, Philip J. Weston, Jane E. Harding Tags: Original Articles Source Type: research

The Impact of the Novel Coronavirus Disease 2019 on Therapy Service Delivery for Children with Disabilities
To assess the impact of the novel coronavirus disease 2019 (COVID-19) pandemic on the delivery of, and parent satisfaction with, therapy services for children with disabilities in early intervention, school, and outpatient settings. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 24, 2020 Category: Pediatrics Authors: Ashley Murphy, Linzy M. Pinkerton, Ellie Bruckner, Heather J. Risser Tags: Original Articles Source Type: research

The Impact of COVID-19 on Therapy Service Delivery for Children with Disabilities
To assess the impact of COVID-19 on the delivery of, and parent satisfaction with, therapy services for children with disabilities in early intervention, school, and outpatient settings. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 24, 2020 Category: Pediatrics Authors: Ashley Murphy, Linzy M. Pinkerton, Ellie Bruckner, Heather J. Risser Tags: Original Articles Source Type: research

Patient Characteristics and Treatment Outcomes of Symptomatic Catheter-Related Arterial Thrombosis in Infants: A Retrospective Cohort Study
To describe the clinical characteristics, outcomes, and adverse events of treatment for symptomatic infant catheter-related arterial thrombosis. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 24, 2020 Category: Pediatrics Authors: Clay T. Cohen, Viia Anderson, Sudhen B. Desai, Athis Arunachalam, Mubbasheer Ahmed, Rosa Diaz Tags: Original Articles Source Type: research

Three Infants with Pathogenic Variants in the ABCA3 Gene: Presentation, Treatment, and Clinical Course
ABCA3 deficiency is a rare cause of neonatal respiratory failure. Biallelic complete loss of function variants lead to neonatal demise without lung transplantation, but children with partial function variants have variable outcomes. The favorable clinical course of 3 such infants presenting with respiratory distress at birth is described. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 23, 2020 Category: Pediatrics Authors: Xin Si, Lea C. Steffes, Jennifer C. Schymick, Florette K. Hazard, Michael C. Tracy, David N. Cornfield Tags: Brief Reports Source Type: research

Delayed Administration of Antibiotics beyond the First Hour of Recognition is Associated with Increased Mortality Rates in Children with Sepsis/Severe Sepsis and Septic Shock
To compare the risk of mortality and other clinical outcomes in children with sepsis/severe sepsis/septic shock who received antibiotics within the first hour of recognition ( ‘early antibiotics’ group) with those who received antibiotics after the first hour (‘delayed antibiotics’ group). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 23, 2020 Category: Pediatrics Authors: Jhuma Sankar, Mohil Garg, Jagat Jeevan Ghimire, M Jeeva Sankar, Rakesh Lodha, S.K. Kabra Tags: Original Articles Source Type: research

Three Infants with Pathogenic Variants in the ABCA3 Gene: Presentation, Treatment and Clinical Course
ABCA3 deficiency is a rare cause of neonatal respiratory failure. Bi-allelic complete loss of function variants lead to neonatal demise without lung transplantation, but children with partial function variants have variable outcomes. The favorable clinical course of three such infants presenting with respiratory distress at birth is described. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 23, 2020 Category: Pediatrics Authors: Si, X., Steffes, L.C., Schymick, J.C., Hazard, F.K., Tracy, M.C., Cornfield, D.N. Tags: Brief Reports Source Type: research

Association between Baseline Cortisol Serum Concentrations and the Effect of Prophylactic Hydrocortisone in Extremely Preterm Infants
To define a nomogram of serum cortisol values before 24 hours of postnatal life for extremely preterm infants and determine whether baseline cortisol values affect the benefit/risk ratio of prophylactic hydrocortisone to improve survival without bronchopulmonary dysplasia (BPD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 23, 2020 Category: Pediatrics Authors: Chloe Renolleau, Artemis Toumazi, Aur élie Bourmaud, Jean-François Benoist, Didier Chevenne, Damir Mohamed, Corinne Alberti, Valérie Biran, Olivier Baud, PREMILOC Trial study group Tags: Original Articles Source Type: research

Long-Term Survival and Causes of Death in Children with Trisomy 21 After Congenital Heart Surgery
To evaluate long-term transplant-free survival and causes of death in the Trisomy 21 (T21) population after surgery for congenital heart disease (CHD) in comparison with euploidic patients. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 23, 2020 Category: Pediatrics Authors: Jennifer K. Peterson, Lazaros K. Kochilas, Jessica Knight, Courtney McCracken, Amanda S. Thomas, James H. Moller, Shaun P. Setty Tags: Original Articles Source Type: research

Meal-Induced Symptoms in Children with Dyspepsia –Relationships to Sex and the Presence of Gastroparesis
To test the hypothesis that in children with dyspepsia, prospective symptom severity following ingestion of a meal would correlate with percent gastric retention, and those ultimately diagnosed with gastroparesis would report worse symptoms. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 22, 2020 Category: Pediatrics Authors: Liz Febo-Rodriguez, Bruno P. Chumpitazi, Salma Musaad, Andrew C. Sher, Robert J. Shulman Tags: Original Articles Source Type: research

Standardized Feeding Approach Mitigates Weight Loss in Infants with Congenital Heart Disease
To evaluate the effect of a standardized feeding approach using a clinical nutrition pathway on weight-for-age Z score (WAZ) over hospital length of stay (HLOS) for infants with congenital heart disease (CHD). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - December 22, 2020 Category: Pediatrics Authors: Amy Jo Lisanti, Melanie Savoca, J. William Gaynor, Maria R. Mascarenhas, Chitra Ravishankar, Erin Sullivan, Karyn Pieciak, Andrew Costarino, Jodi Chen, Andrea Kennedy, Robert Olsen, Jungwon Min, Antara Mondal, Jing Huang, Sharon Y. Irving Tags: Original Articles Source Type: research