The KT Jeang Retrovirology prize 2017: Michael Emerman
(Source: Retrovirology)
Source: Retrovirology - June 21, 2017 Category: Virology Source Type: research
HIV drug resistance against strand transfer integrase inhibitors
Integrase strand transfer inhibitors (INSTIs) are the newest class of antiretroviral drugs to be approved for treatment and act by inhibiting the essential HIV protein integrase from inserting the viral DNA ge... (Source: Retrovirology)
Source: Retrovirology - June 5, 2017 Category: Virology Authors: Kaitlin Anstett, Bluma Brenner, Thibault Mesplede and Mark A. Wainberg Source Type: research
Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee
Simian immunodeficiency virus of chimpanzees (SIVcpz), the progenitor of human immunodeficiency virus type 1 (HIV-1), is associated with increased mortality and AIDS-like immunopathology in wild-living chimpan... (Source: Retrovirology)
Source: Retrovirology - June 2, 2017 Category: Virology Authors: Hannah J. Barbian, Raven Jackson-Jewett, Corrine S. Brown, Frederic Bibollet-Ruche, Gerald H. Learn, Timothy Decker, Edward F. Kreider, Yingying Li, Thomas N. Denny, Paul M. Sharp, George M. Shaw, Jeffrey Lifson, Edward P. Acosta, Michael S. Saag, Kathari Source Type: research
Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or les... (Source: Retrovirology)
Source: Retrovirology - May 31, 2017 Category: Virology Authors: Franziska K. Geis, Melanie Galla, Dirk Hoffmann, Johannes Kuehle, Daniela Zychlinski, Tobias Maetzig, Juliane W. Schott, Adrian Schwarzer, Christine Goffinet, Stephen P. Goff and Axel Schambach Source Type: research
Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup
Parent-offspring (PO) regression is a central tool to determine the heritability of phenotypic traits; i.e., the relative extent to which those traits are controlled by genetic factors. The applicability of PO... (Source: Retrovirology)
Source: Retrovirology - May 23, 2017 Category: Virology Authors: Nadine Bachmann, Teja Turk, Claus Kadelka, Alex Marzel, Mohaned Shilaih, J ürg Böni, Vincent Aubert, Thomas Klimkait, Gabriel E. Leventhal, Huldrych F. Günthard and Roger Kouyos Source Type: research
