Chemical characterization and antimicrobial activity of < em > Baccharis vulneraria < /em > Baker essential oil against strains of microorganisms that cause cutaneous infections
Nat Prod Res. 2023 May 19:1-5. doi: 10.1080/14786419.2023.2214840. Online ahead of print.ABSTRACTBaccharis vulneraria Baker is used popularly for the treatment of skin infections. So, this study aimed investigate the antimicrobial activity and chemical characterization of the essential oil (EO) against microorganisms that cause cutaneous infections. The EO was analyzed by GC-MS. The antimicrobial test was performed using the serial microdilution method, and the antimicrobial activity was determined by the minimum inhibitory concentration against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomon...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: K étlin Fernanda Rodrigues Daiane Heidrich Fernanda Fensterseifer Manoela Teixeira Roso Fernanda Bruxel Eduardo Miranda Ethur Luc élia Hoehne Elisete Maria de Freitas Source Type: research
Evaluating the application of an arabinoxylan-rich fraction from brewers' spent grain as a release modifier of drugs
This study evaluated the possible use of a fraction of brewers' spent grain rich in arabinoxylans (BSG-AX) as an excipient that modifies the release of class III drugs (Biopharmaceutics Classification System), by determining the release profile of metformin hydrochloride (MH), in a water medium. The cumulative percentage of MH release showed the best linear fit when modeled with the cumulative distribution function (CDF) of the Weibull distribution (R2 = 0.993 ± 0.001). According to the Korsmeyer-Peppas model, the first stage of MH release is regulated by a super case-II transport mechanism controlled by the expansion and...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Laura Garc ía-Curiel Jes ús Guadalupe Pérez-Flores Elizabeth Contreras-L ópez Emmanuel P érez-Escalante Rita Paz-Samaniego Source Type: research
Encapsulation of propolis extract in ovalbumin protein particles: characterization and in vitro digestion
The objective of this study was to microencapsulate propolis by spray drying. The best condition for microencapsulation was achieved with 4% ovalbumin at 120 °C, where there was the greatest encapsulation efficiency (88.20%) and spherical shape. However, the increase of ovalbumin concentration resulted lower yields (< 52%). As for the scanning electron microscopy (SEM), the increase of ovalbumin concentration caused an increase of the size with average diameter and formation of spherical microcapsules. The phenolic compounds were already released in the gastric fluid condition (stomach).PMID:37203338 | DOI:10.1080/1478...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Cristina Jansen-Alves Francine N Victoria Caroline D Borges Rui C Zambiazi Source Type: research
Aphid < em > Cerosipha forbesi < /em > control using < em > Piper macedoi < /em > Yunck essential oil in strawberry crop
Nat Prod Res. 2023 May 19:1-6. doi: 10.1080/14786419.2023.2214832. Online ahead of print.ABSTRACTStrawberry is a food rich in bioactive compounds with great antioxidant potential. However, due to the high incidence of pests that affect crop cultivation, phytosanitary management still lacks control methods for agroecological cultivation. Thus, the present research aimed to evaluate the chemical composition and the potential of the essential oil of the leaves of Piper macedoi in the control of Cerosipha forbesi in laboratory and semi-field conditions. The concentration of essential oil in the leaves of P. macedoi that showed...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Ana Terra Bravim Dos Santos Vanessa Sessa Dian Luciana Alves Parreira Maicon Pierre Louren ço Jos é Salazar Zanuncio Junior Ester Gon çalves de Jesus Mario Ferreira Concei ção Santos Luciano Menini Source Type: research
Chemical characterization and antimicrobial activity of < em > Baccharis vulneraria < /em > Baker essential oil against strains of microorganisms that cause cutaneous infections
Nat Prod Res. 2023 May 19:1-5. doi: 10.1080/14786419.2023.2214840. Online ahead of print.ABSTRACTBaccharis vulneraria Baker is used popularly for the treatment of skin infections. So, this study aimed investigate the antimicrobial activity and chemical characterization of the essential oil (EO) against microorganisms that cause cutaneous infections. The EO was analyzed by GC-MS. The antimicrobial test was performed using the serial microdilution method, and the antimicrobial activity was determined by the minimum inhibitory concentration against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomon...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: K étlin Fernanda Rodrigues Daiane Heidrich Fernanda Fensterseifer Manoela Teixeira Roso Fernanda Bruxel Eduardo Miranda Ethur Luc élia Hoehne Elisete Maria de Freitas Source Type: research
Evaluating the application of an arabinoxylan-rich fraction from brewers' spent grain as a release modifier of drugs
This study evaluated the possible use of a fraction of brewers' spent grain rich in arabinoxylans (BSG-AX) as an excipient that modifies the release of class III drugs (Biopharmaceutics Classification System), by determining the release profile of metformin hydrochloride (MH), in a water medium. The cumulative percentage of MH release showed the best linear fit when modeled with the cumulative distribution function (CDF) of the Weibull distribution (R2 = 0.993 ± 0.001). According to the Korsmeyer-Peppas model, the first stage of MH release is regulated by a super case-II transport mechanism controlled by the expansion and...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Laura Garc ía-Curiel Jes ús Guadalupe Pérez-Flores Elizabeth Contreras-L ópez Emmanuel P érez-Escalante Rita Paz-Samaniego Source Type: research
Encapsulation of propolis extract in ovalbumin protein particles: characterization and in vitro digestion
The objective of this study was to microencapsulate propolis by spray drying. The best condition for microencapsulation was achieved with 4% ovalbumin at 120 °C, where there was the greatest encapsulation efficiency (88.20%) and spherical shape. However, the increase of ovalbumin concentration resulted lower yields (< 52%). As for the scanning electron microscopy (SEM), the increase of ovalbumin concentration caused an increase of the size with average diameter and formation of spherical microcapsules. The phenolic compounds were already released in the gastric fluid condition (stomach).PMID:37203338 | DOI:10.1080/1478...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Cristina Jansen-Alves Francine N Victoria Caroline D Borges Rui C Zambiazi Source Type: research
Aphid < em > Cerosipha forbesi < /em > control using < em > Piper macedoi < /em > Yunck essential oil in strawberry crop
Nat Prod Res. 2023 May 19:1-6. doi: 10.1080/14786419.2023.2214832. Online ahead of print.ABSTRACTStrawberry is a food rich in bioactive compounds with great antioxidant potential. However, due to the high incidence of pests that affect crop cultivation, phytosanitary management still lacks control methods for agroecological cultivation. Thus, the present research aimed to evaluate the chemical composition and the potential of the essential oil of the leaves of Piper macedoi in the control of Cerosipha forbesi in laboratory and semi-field conditions. The concentration of essential oil in the leaves of P. macedoi that showed...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Ana Terra Bravim Dos Santos Vanessa Sessa Dian Luciana Alves Parreira Maicon Pierre Louren ço Jos é Salazar Zanuncio Junior Ester Gon çalves de Jesus Mario Ferreira Concei ção Santos Luciano Menini Source Type: research
Chemical characterization and antimicrobial activity of < em > Baccharis vulneraria < /em > Baker essential oil against strains of microorganisms that cause cutaneous infections
Nat Prod Res. 2023 May 19:1-5. doi: 10.1080/14786419.2023.2214840. Online ahead of print.ABSTRACTBaccharis vulneraria Baker is used popularly for the treatment of skin infections. So, this study aimed investigate the antimicrobial activity and chemical characterization of the essential oil (EO) against microorganisms that cause cutaneous infections. The EO was analyzed by GC-MS. The antimicrobial test was performed using the serial microdilution method, and the antimicrobial activity was determined by the minimum inhibitory concentration against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomon...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: K étlin Fernanda Rodrigues Daiane Heidrich Fernanda Fensterseifer Manoela Teixeira Roso Fernanda Bruxel Eduardo Miranda Ethur Luc élia Hoehne Elisete Maria de Freitas Source Type: research
Evaluating the application of an arabinoxylan-rich fraction from brewers' spent grain as a release modifier of drugs
This study evaluated the possible use of a fraction of brewers' spent grain rich in arabinoxylans (BSG-AX) as an excipient that modifies the release of class III drugs (Biopharmaceutics Classification System), by determining the release profile of metformin hydrochloride (MH), in a water medium. The cumulative percentage of MH release showed the best linear fit when modeled with the cumulative distribution function (CDF) of the Weibull distribution (R2 = 0.993 ± 0.001). According to the Korsmeyer-Peppas model, the first stage of MH release is regulated by a super case-II transport mechanism controlled by the expansion and...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Laura Garc ía-Curiel Jes ús Guadalupe Pérez-Flores Elizabeth Contreras-L ópez Emmanuel P érez-Escalante Rita Paz-Samaniego Source Type: research
Encapsulation of propolis extract in ovalbumin protein particles: characterization and in vitro digestion
The objective of this study was to microencapsulate propolis by spray drying. The best condition for microencapsulation was achieved with 4% ovalbumin at 120 °C, where there was the greatest encapsulation efficiency (88.20%) and spherical shape. However, the increase of ovalbumin concentration resulted lower yields (< 52%). As for the scanning electron microscopy (SEM), the increase of ovalbumin concentration caused an increase of the size with average diameter and formation of spherical microcapsules. The phenolic compounds were already released in the gastric fluid condition (stomach).PMID:37203338 | DOI:10.1080/1478...
Source: Natural Product Research - May 19, 2023 Category: Biochemistry Authors: Cristina Jansen-Alves Francine N Victoria Caroline D Borges Rui C Zambiazi Source Type: research
Cytotoxicity sesquiterpenoids from the leaves of < em > Datura stramonium < /em > L
Nat Prod Res. 2023 May 17:1-8. doi: 10.1080/14786419.2023.2214292. Online ahead of print.ABSTRACTFour new sesquiterpenoids, dstramonins A-D (1-4), and one new natural product (5), together with three known compounds (6-8), were isolated from the leaves of Datura stramonium L. The structures of new compounds were elucidated by extensive spectroscopic analysis and comparison with the literature. The cytotoxicity of isolates against LN229 cells was assessed and compounds 2-4, and 7 displayed cytotoxic activity with IC50 values ranging from 8.03 to 13.83 μM.PMID:37198914 | DOI:10.1080/14786419.2023.2214292 (Source: Natural Product Research)
Source: Natural Product Research - May 18, 2023 Category: Biochemistry Authors: Juan Pan Yan Liu Ao-Fei Wang Jia-Tong Wu Rui Yang Wei Guan Adnan Mohammed Algradi Hai-Xue Kuang Bing-You Yang Source Type: research
Cytotoxicity sesquiterpenoids from the leaves of < em > Datura stramonium < /em > L
Nat Prod Res. 2023 May 17:1-8. doi: 10.1080/14786419.2023.2214292. Online ahead of print.ABSTRACTFour new sesquiterpenoids, dstramonins A-D (1-4), and one new natural product (5), together with three known compounds (6-8), were isolated from the leaves of Datura stramonium L. The structures of new compounds were elucidated by extensive spectroscopic analysis and comparison with the literature. The cytotoxicity of isolates against LN229 cells was assessed and compounds 2-4, and 7 displayed cytotoxic activity with IC50 values ranging from 8.03 to 13.83 μM.PMID:37198914 | DOI:10.1080/14786419.2023.2214292 (Source: Natural Product Research)
Source: Natural Product Research - May 18, 2023 Category: Biochemistry Authors: Juan Pan Yan Liu Ao-Fei Wang Jia-Tong Wu Rui Yang Wei Guan Adnan Mohammed Algradi Hai-Xue Kuang Bing-You Yang Source Type: research
Four dodecanoic acid derivatives from the cold-seep-derived fungus < em > Cladosporium cladosporioides < /em > 8-1
Nat Prod Res. 2023 May 17:1-6. doi: 10.1080/14786419.2023.2214291. Online ahead of print.ABSTRACTTwo new compounds, cladospolides I (1) and J (2), together with two new naturally occurring ones, methyl 11-hydroxy-4-oxododecanoate (3) and 11-hydroxy-4-oxododecanoic acid (4), were isolated from the culture extract of the cold-seep sediment-derived fungus Cladosporium cladosporioides 8-1. Their structures and configurations were established by analysis of 1D/2D NMR, MS, ECD, and specific optical rotation data. Compound 3 was possibly formed by methyl esterification of 4 during the purification process due to the utilization o...
Source: Natural Product Research - May 17, 2023 Category: Biochemistry Authors: Chang-Peng Li Yin-Ping Song Xiao-Rui Liang Nai-Yun Ji Source Type: research
Antioxidant isolation and characterization from the plant < em > Tradescantia spathacea < /em > Sw. of the Commelinaceae family
Nat Prod Res. 2023 May 17:1-8. doi: 10.1080/14786419.2023.2213806. Online ahead of print.ABSTRACTA novel bioactive flavan glycoside was isolated by solvent extraction method with the help of Soxhlet apparatus from the methanolic extract of Tradescantia spathacea Sw. Flavan glycoside having molecular formula C20H22O10, melting point 175-1780C, molecular weight by ESI-MS m/z (M + H]+ 423, optical rotation was[α]21D-45.1(c 0.20 methanol). Its structure was determined (-)-epicatechin 7-O-alpha-L-arabinopyranoside. Various color reactions, chemical degradation (like acid hydrolysis, permethylation, and enzymatic hydrolysis), U...
Source: Natural Product Research - May 17, 2023 Category: Biochemistry Authors: Kesar Singh R N Yadava Ritu Yadav Source Type: research
